PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus NDN AUP1 17353931 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TCTN2 AUP1 26638075 biogrid,intact exp GP G G G GP GP G GP GP G G G GP G G GP GP G GP G GP G G G GP GP GP GP G ACSF3 AUP1 21857022 biogrid exp GP GP G GP P G P P P P P P GP P P P G P P P P GP P P GP RNF139 AUP1 23223569 biogrid exp G GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP G GP GP G GP GP G SURF4 AUP1 22119785 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2G2 AUP1 23223569,21857022,21127063,22119785,17353931 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G MDC1 AUP1 22990118 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CKAP5 AUP1 22119785 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PRKDC AUP1 22119785 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PTP4A1 AUP1 26186194 biogrid exp G GP G G G G G G G G G G G G G GP G GP G G G G G G GP G GP G G STT3B AUP1 21857022 biogrid exp GP GP G G G GP G GP GP G G G GP G G G GP G GP G GP G G GP G G GP GP G UBL4A AUP1 23246001 biogrid exp GP GP G G G GP G G GP G GP G G G G G GP G GP G GP G G G G G GP P G LPCAT1 AUP1 21857022 biogrid exp GP GP G G GP GP G P GP G GP P GP GP G GP GP GP GP G GP GP GP P GP GP GP P G PCMTD2 AUP1 26186194 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPN2 AUP1 21857022 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TMEM248 AUP1 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G G GP GP GP G GP G GP G G G G GP G SPTLC1 AUP1 21857022 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CLN3 AUP1 23464991,20562859 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G OS9 AUP1 21857022 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G VCP AUP1 21857022 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G APOB AUP1 26186194 biogrid exp G G G G G G G G G G G GP G G G G G G GP G G G OPRD1 AUP1 23840749 biogrid exp P P P P P P P P G P P P SEL1L AUP1 21857022,18711132,22119785 biogrid,dip exp GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G RNF114 AUP1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DDOST AUP1 21857022 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G NTRK1 AUP1 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P OPRM1 AUP1 23840749 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G GP G FAM175B AUP1 26186194 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RNF11 AUP1 15231748 biogrid,i2d,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DIP2B AUP1 22119785 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SYVN1 AUP1 21857022,22119785 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KPTN AUP1 17353931 biogrid exp P GP G P GP G GP GP G GP GP GP GP GP GP P P G P GP GP GP GP GP GP GP G SLC38A1 AUP1 25561175 intact exp GP GP G G G GP G G GP G GP GP G GP G GP GP G GP G GP G G G GP G GP P G TUBA1C AUP1 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KCND3 AUP1 17725712 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G P GP GP G GP GP G GP G ITGA1 AUP1 12042322 hprd,biogrid exp GP GP P P P P P P P G P P P P P GP P P GP G GP P CAPRIN2 AUP1 22119785 biogrid exp GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G G G G GP GP G GP GP G UBE2J1 AUP1 21857022,20435896 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G MAGEA6 AUP1 17353931 intact exp G FNTB AUP1 26186194 biogrid exp P GP P GP GP G GP GP P P G GP GP GP P G P GP P GP P GP GP GP TMEM216 AUP1 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ILK AUP1 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FBXO6 AUP1 22268729 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G ATG12 AUP1 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TCTN3 AUP1 26638075 biogrid,intact exp G GP G G G GP G GP GP G G G G G G GP GP G GP G GP GP G GP GP G GP G G TUBG1 AUP1 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPRK1 AUP1 23840749 biogrid,intact exp P P G GP G P G P P P P GP GP GP G GP P P P P FBXW11 AUP1 25515538 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TMEM17 AUP1 26638075 biogrid,intact exp P GP G P GP G P P G GP P P G G P GP P GP G P GP GP P P P P GP UBE2E3 AUP1 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G HMGCR AUP1 23223569 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BRF2 AUP1 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBC AUP1 21857022 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FAF2 AUP1 21857022, 21836163 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ITGA5 AUP1 12042322, 21836163 hprd,biogrid exp, pred G G G G G G G G G G GP G G G G G G G G GP G G G G G G G G AMFR AUP1 23223569, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ITGAM AUP1 12042322, 21836163 hprd,biogrid exp, pred G G G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G ITGA2B AUP1 12042322, 25402006 hprd,biogrid exp, pred G G G G GP G G G G G G G G G G G G G G G G G G G G G AUP1 AUP1 17353931, 23023127 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ITGA2 AUP1 12042322, 21836163 hprd,biogrid exp, pred GP GP P GP G GP GP G GP GP GP G G GP GP GP GP G G GP GP P GP GP GP P G ITGAV AUP1 12042322, 21836163 hprd,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP G G G G GP GP GP G GP GP G G G GP GP GP G HSD3B7 AUP1 ortho G P P P P GP GP P G P P GP P P P P YWHAE AUP1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AUP1 NUMBL ortho G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G G GP G RGL2 AUP1 23023127 pred GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G G GP G GP GP G GP GP G RNF181 AUP1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBL5 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2Q1 AUP1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2B AUP1 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G TNRC6C AUP1 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G NFATC2IP AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IFI16 AUP1 23023127 pred G G G G GP GP G G GP G GP G G GP G G GP GP G G G G G G G GP G G G CBLB AUP1 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G SAMD9 AUP1 23023127 pred GP GP G GP P G GP GP P GP GP GP G GP P GP P P P P P GP GP GP P SYK AUP1 21836163 pred GP G G G GP GP G GP G GP G GP GP G GP GP GP G G G G G GP GP GP GP G CIDEA AUP1 23023127 pred G G G G G G G G NCF2 AUP1 23023127 pred G G GP G G G GP GP G G G G G G G G GP G G TAB2 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2A AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAD23A AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ITGB3 AUP1 25402006 pred GP G G G GP GP G GP G G GP G GP G G G GP G G G G G G G G G GP G ASCC2 AUP1 23023127 pred GP GP G G P GP GP GP GP GP GP G GP P GP P G GP GP GP GP GP GP GP GP G UBAP2L AUP1 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBTD1 AUP1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G G GP GP GP G P G GP G G G GP G MIDN AUP1 23023127 pred GP GP G G GP GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G UHRF2 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UTRN AUP1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HERPUD2 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TMUB2 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NSMCE1 AUP1 23023127 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G HUWE1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NXF2, NXF2B AUP1 23023127 pred UBXN10 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP GP GP GP G GP GP GP GP GP G GP GP G UBXN8 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NSFL1C AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TMUB1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G ZSCAN9 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G TDRD3 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP PLEKHH3 AUP1 23023127 pred G GP G GP P P GP G P G G GP G G P GP G G GP GP GP G VCX AUP1 23023127 pred P P INPPL1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ASPSCR1 AUP1 23023127 pred GP GP G P GP G GP P G GP GP GP GP G GP GP P GP G GP GP GP GP GP G GP GP CUEDC1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP P G UBQLNL AUP1 23023127 pred P P P P P P P P G P P P P GP AXIN1 AUP1 23023127 pred GP GP G GP GP G P GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM56 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G P GP GP GP GP G DVL2 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CIB1 AUP1 23023127 pred GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G GP GP GP GP GP G GP GP G NFKB1 AUP1 23023127 pred GP G G G GP G G G GP G G G GP GP G GP G G G G GP GP GP G GP GP G GP G UBXN11 AUP1 23023127 pred G GP G G G GP G GP P G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G FRMD7 AUP1 23023127 pred P P P P P P P P P P P P P P P P P P P FRMD8 AUP1 23023127 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G TCEB2 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VPS4A AUP1 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CIDEC AUP1 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOLLIP AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G ARAF AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCE1 AUP1 23023127 pred GP P G P GP G GP GP G GP P GP P G GP GP GP GP G P GP GP GP GP GP GP P G RGS14 AUP1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G BCL10 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBAC1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G C19orf53 AUP1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HERPUD1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EFHB AUP1 23023127 pred G UBL7 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G OASL AUP1 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G PTPN13 AUP1 23023127 pred GP GP G P GP G G GP G GP GP GP G GP GP GP GP G P GP GP GP GP GP GP G UBC AUP1 23023127 pred CETN3 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G MID1 AUP1 23023127 pred G G G GP G GP GP G GP G G G G GP GP G GP G GP G G GP GP G GP GP G SQSTM1 AUP1 23023127 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP GP GP GP GP GP GP G UFM1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RP1L1 AUP1 23023127 pred G TNFRSF1A AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G URI1 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MSN AUP1 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP GP G G GP G GP G NXF1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TSSC4 AUP1 23023127 pred GP P P G GP G P G GP GP G GP P GP G GP P P GP GP G GP GP G DVL3 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SDF4 AUP1 23023127 pred GP GP G G G GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G UBTD2 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G DEK AUP1 23023127 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EDF1 AUP1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G BAG6 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NUB1 AUP1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBQLN3 AUP1 23023127 pred G G G G G G GP G LONP1 AUP1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RASIP1 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO2 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MYD88 AUP1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TFG AUP1 23023127 pred G GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP G GP G GP GP G RAF1 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FAU AUP1 23023127 pred GP G G G GP GP G GP GP G G GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G COL2A1 AUP1 25402006 pred G G G P P P G G P GP G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9Y3C5 Q9Y679 - 15231748 - X 2 Q9Y679 pull down 21911578 association C 306 Q81KA0 Q9Y679 two hybrid pooling approach 20711500 physical association X 2 Q99608 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9HAW0 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 Q969T4 Q9Y679 two hybrid 19549727 physical association X 2 P43360 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y679 P35372 anti tag coimmunoprecipitation 23840749 physical association X 2 Q9Y679 P35372 two hybrid 23840749 physical association X 2 Q9Y679 P35372 two hybrid 23840749 physical association X 2 Q9Y679 P35372 pull down 23840749 physical association X 2 Q9Y679 anti tag coimmunoprecipitation 25561175 association C 53 Q9Y679 anti tag coimmunoprecipitation 20562859 physical association C 38 Q13418 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 P60604 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 P41145 Q9Y679 anti tag coimmunoprecipitation 23840749 physical association X 2 Q9Y3C5 Q9Y679 two hybrid 15231748 physical association X 2 Q9Y679 Q81K85 two hybrid pooling approach 20711500 physical association X 2 Q9Y679 P32300 anti tag coimmunoprecipitation 23840749 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality ATG12 AUP1 17353931,17353931 0006,0004 HT APOB AUP1 26186194 0004 HT TUBG1 AUP1 26496610,26496610 0007,0004 HT MAGEA6 AUP1 17353931 0006 HT FNTB AUP1 26186194 0004 HT UBE2G2 AUP1 23223569,22119785,21127063,21857022,17353931,17353931 0004,0004,0096,0004,0006,0004 LC,HT CLN3 AUP1 20562859,23464991,20562859 0007,0004,0004 HT,LC ILK AUP1 17353931,17353931 0006,0004 HT FAM175B AUP1 26186194 0004 HT TCTN3 AUP1 26638075,26638075 1314,1313 HT SYVN1 AUP1 21857022,22119785 0004,0004 LC TMEM17 AUP1 26638075,26638075 1314,1313 HT PTP4A1 AUP1 26186194 0004 HT FAF2 AUP1 21857022,26389662 0004,0004 LC TCTN2 AUP1 26638075,26638075 1314,1313 HT NDN AUP1 17353931,17353931 0006,0004 HT TUBA1C AUP1 26496610,26496610 0007,0004 HT BRF2 AUP1 17353931 0006 HT PCMTD2 AUP1 26186194 0004 HT TMEM248 AUP1 26496610,26496610 0007,0004 HT TMEM216 AUP1 26638075,26638075 1314,1313 HT SEL1L AUP1 18711132,22119785,21857022,18711132 0007,0004,0004,0004 LC UBE2J1 AUP1 21857022,20435896 0004,0004 LC RNF114 AUP1 26186194 0004 HT KPTN AUP1 17353931 0004 HT AUP1 HEL-S-28 17353931 0004 HT ATG12 AUP1 17353931,17353931 0006,0004 HT APOB AUP1 26186194 0004 HT TUBG1 AUP1 26496610,26496610 0007,0004 HT MAGEA6 AUP1 17353931 0006 HT FNTB AUP1 26186194 0004 HT UBE2G2 AUP1 17353931,17353931 0006,0004 HT CLN3 AUP1 20562859,20562859 0007,0004 HT ILK AUP1 17353931,17353931 0006,0004 HT FAM175B AUP1 26186194 0004 HT TCTN3 AUP1 26638075,26638075 1314,1313 HT TMEM17 AUP1 26638075,26638075 1314,1313 HT PTP4A1 AUP1 26186194 0004 HT TCTN2 AUP1 26638075,26638075 1314,1313 HT NDN AUP1 17353931,17353931 0006,0004 HT TUBA1C AUP1 26496610,26496610 0007,0004 HT BRF2 AUP1 17353931 0006 HT PCMTD2 AUP1 26186194 0004 HT TMEM248 AUP1 26496610,26496610 0007,0004 HT TMEM216 AUP1 26638075,26638075 1314,1313 HT RNF114 AUP1 26186194 0004 HT KPTN AUP1 17353931 0004 HT AUP1 HEL-S-28 17353931 0004 HT UBE2G2 AUP1 23223569,22119785,21127063,21857022 0004,0004,0096,0004 LC CLN3 AUP1 23464991 0004 LC SYVN1 AUP1 21857022,22119785 0004,0004 LC FAF2 AUP1 21857022,26389662 0004,0004 LC SEL1L AUP1 18711132,22119785,21857022,18711132 0007,0004,0004,0004 LC UBE2J1 AUP1 21857022,20435896 0004,0004 LC B7Z8B0 AUP1 12042322 0018 LC ITGAV AUP1 12042322 0018 LC ITGA2B AUP1 12042322,12042322,12042322 0096,0018,0004 LC ITGA5 AUP1 12042322 0018 LC ITGAM AUP1 12042322 0018 LC ITGA2 AUP1 12042322 0018 LC OPRM1 AUP1 23840749,23840749,23840749,23840749 0096,0007,0018,0004 LC ITGA1 AUP1 12042322 0018 LC MDC1 AUP1 22990118,22990118 0018,0004 LC UBE2E3 AUP1 19549727 0018 HT RNF11 AUP1 15231748 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y679 Q9NRD1 AUP1 FBXO6 0.126 22268729 Q9Y679 Q9H2H9 AUP1 SLC38A1 0.126 25561175 Q9Y679 Q9Y664 AUP1 KPTN 0.126 17353931 Q9Y679 O15260 AUP1 SURF4 0.126 22119785 Q9Y679 O15269 AUP1 SPTLC1 0.21 21857022 Q9Y679 O94817 AUP1 ATG12 0.332 17353931 Q9Y679 P04114 AUP1 APOB 0.126 26186194 Q9Y679 P04844 AUP1 RPN2 0.21 21857022 Q9Y679 P06756 AUP1 ITGAV 0.309 12042322 Q9Y679 P08648 AUP1 ITGA5 0.309 12042322 Q9Y679 P0CG48 AUP1 UBC 0.376 21857022 Q9Y679 P11215 AUP1 ITGAM 0.309 12042322 Q9Y679 P17301 AUP1 ITGA2 0.309 12042322 Q9Y679 P39656 AUP1 DDOST 0.21 21857022 Q9Y679 P43360 AUP1 MAGEA6 0.126 17353931 Q9Y679 P49356 AUP1 FNTB 0.126 26186194 Q9Y679 P55072 AUP1 VCP 0.21 21857022 Q9Y679 P56199 AUP1 ITGA1 0.309 12042322 Q9Y679 P78527 AUP1 PRKDC 0.126 22119785 Q9Y679 Q13438 AUP1 OS9 0.21 21857022 Q9Y679 Q14008 AUP1 CKAP5 0.126 22119785 Q9Y679 Q15018 AUP1 FAM175B 0.126 26186194 Q9Y679 Q4G176 AUP1 ACSF3 0.21 21857022 Q9Y679 Q6IMN6 AUP1 CAPRIN2 0.126 22119785 Q9Y679 Q81KA0 AUP1 Q81KA0 0.126 20711500 Q9Y679 Q8NF37 AUP1 LPCAT1 0.21 21857022 Q9Y679 Q8TCJ2 AUP1 STT3B 0.21 21857022 Q9Y679 Q93096 AUP1 PTP4A1 0.126 26186194 Q9Y679 Q99608 AUP1 NDN 0.332 17353931 Q9Y679 Q9HAW0 AUP1 BRF2 0.126 17353931 Q9Y679 Q9NV79 AUP1 PCMTD2 0.126 26186194 Q9Y679 Q9P265 AUP1 DIP2B 0.126 22119785 Q9Y679 Q9Y385 AUP1 UBE2J1 0.376 20435896,21857022 Q9Y679 Q9Y508 AUP1 RNF114 0.126 26186194 Q9Y679 Q77M19 AUP1 P 0.126 21911578 Q9Y679 Q81K85 AUP1 GLGA 0.126 20711500 Q9Y679 Q86TM6 AUP1 SYVN1 0.396 21857022,22119785 Q9Y679 Q86X19 AUP1 TMEM17 0.126 26638075 Q9Y679 P11441 AUP1 UBL4A 0.126 23246001 Q9Y679 P04035 AUP1 HMGCR 0.21 23223569 Q9Y679 P04544 AUP1 1C 0.126 22593156 Q9Y679 P04629 AUP1 NTRK1 0.126 25921289 Q9Y679 P06460 AUP1 P06460 0.126 22810586 Q9Y679 Q9P0N5 AUP1 TMEM216 0.236 26638075 Q9Y679 Q9NWD8 AUP1 TMEM248 0.236 26496610 Q9Y679 Q8N8J0 AUP1 PI4KAP1 0.236 unassigned1304 Q9Y679 Q9Y3C5 AUP1 RNF11 0.332 15231748 Q9Y679 Q96GX1 AUP1 TCTN2 0.236 26638075 Q9Y679 Q9BQE3 AUP1 TUBA1C 0.236 26496610 Q9Y679 Q14676 AUP1 MDC1 0.286 22990118 Q9Y679 P23258 AUP1 TUBG1 0.236 26496610 Q9Y679 Q6NUS6 AUP1 TCTN3 0.236 26638075 Q9Y679 O08581 AUP1 KCNK1 0.236 26496610 Q9Y679 P36895 AUP1 BMPR1A 0.236 26496610 Q9Y679 P41145 AUP1 OPRK1 0.236 23840749 Q9Y679 Q8BH74 AUP1 NUP107 0.236 26496610 Q9Y679 P35372 AUP1 OPRM1 0.636 23840749 Q9Y679 P08514 AUP1 ITGA2B 0.623 12042322 Q9Y679 P60604 AUP1 UBE2G2 0.808 21127063,21857022,unassigned1304,17353931,23223569,22119785 Q9Y679 Q13286 AUP1 CLN3 0.332 20562859,23464991 Q9Y679 Q8WU17 AUP1 RNF139 0.21 23223569 Q9Y679 Q969T4 AUP1 UBE2E3 0.183 19549727 Q9Y679 Q96CS3 AUP1 FAF2 0.309 26389662,21857022 Q9Y679 P32300 AUP1 OPRD1 0.126 23840749 Q9Y679 Q9UBV2 AUP1 SEL1L 0.569 21857022,22119785,18711132 Q9Y679 Q9UK17 AUP1 KCND3 0.21 17725712 Q9Y679 Q9UKB1 AUP1 FBXW11 0.126 25515538 Q9Y679 Q9UKV5 AUP1 AMFR 0.21 23223569 Q9Y679 P41143 AUP1 OPRD1 0.126 23840749 Q9Y679 I6T1Z2 AUP1 NS1 {ECO:0000313|EMBL:AFM71862.1} 0.126 unassigned1333 Q9Y679 Q13418 AUP1 ILK 0.236 17353931

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 KCNK1 AUP1 MI:0362 inference MI:0461 interaction database UBD AUP1 MI:0045 experimental interaction detection MI:0461 interaction database SURF4 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database SPTLC1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database MYC AUP1 MI:0045 experimental interaction detection MI:0461 interaction database HMGCR AUP1 MI:0045 experimental interaction detection MI:0461 interaction database APOB AUP1 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database RPN2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ITGAV AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ITGA2B AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ITGA5 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database UBC AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ITGAM AUP1 MI:0045 experimental interaction detection MI:0461 interaction database UBL4A AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ITGA2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TAF1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TUBG1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database OPRM1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database BMPR1A AUP1 MI:0362 inference MI:0461 interaction database DDOST AUP1 MI:0045 experimental interaction detection MI:0461 interaction database OPRD1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database OPRK1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database HNF4A AUP1 MI:0045 experimental interaction detection MI:0461 interaction database MAGEA6 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database FNTB AUP1 MI:0045 experimental interaction detection MI:0461 interaction database VCP AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ITGA1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database NUP107 AUP1 MI:0362 inference MI:0461 interaction database UBE2G2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database MAX AUP1 MI:0045 experimental interaction detection MI:0461 interaction database PRKDC AUP1 MI:0045 experimental interaction detection MI:0461 interaction database CLN3 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ILK AUP1 MI:0045 experimental interaction detection MI:0461 interaction database OS9 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database CKAP5 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database MDC1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database FAM175B AUP1 MI:0045 experimental interaction detection MI:0461 interaction database ACSF3 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database CAPRIN2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TCTN3 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database SYVN1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TMEM17 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database LPCAT1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database STT3B AUP1 MI:0045 experimental interaction detection MI:0461 interaction database RNF139 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database PTP4A1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database FAF2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TCTN2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database NDN AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TUBA1C AUP1 MI:0045 experimental interaction detection MI:0461 interaction database SLC38A1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database BRF2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO6 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database PCMTD2 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TMEM248 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database TMEM216 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database DIP2B AUP1 MI:0045 experimental interaction detection MI:0461 interaction database SEL1L AUP1 MI:0045 experimental interaction detection MI:0461 interaction database KCND3 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database FBXW11 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database AMFR AUP1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2J1 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database RNF11 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database RNF114 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database KPTN AUP1 MI:0045 experimental interaction detection MI:0461 interaction database AUP1 NUMBL MI:0362 inference MI:0461 interaction database