PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus FBXO15 HINT3 26186194 biogrid exp G G G G G G G G G G G G G G ABCB1 FBXO15 23465077 biogrid exp G G G G G G G G G G G G G G FBXO15 SRPK1 23602568 intact exp G G G G G G G G G G G G G G UBA7 FBXO15 23465077 biogrid exp CPA6 FBXO15 26186194 biogrid exp G OS9 FBXO15 26186194 biogrid exp G G G G G G G G G G G G G G FBXO15 CRLS1 24703837 biogrid exp, ortho G G G G G G G G G G G G G G SKP1 FBXO15 10531037, 25402006, 23023127 hprd exp, ortho, pred G G G G G G G G G G G G G G NR0B1 FBXO15 ortho G G G G FBXO15 TFCP2L1 ortho G G G G G G G G G G G G G G ESRRB FBXO15 ortho G POU5F1 FBXO15 ortho CUL1 FBXO15 25402006 ortho, pred G G G G G G G G G G G G G G FBXO15 BAIAP2 23023127 pred G G G G G G G G G G G G SOX2 FBXO15 21836163 pred G G G G G G G G G KLF4 FBXO15 21836163 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8NCQ5 Q96SB4 protein kinase assay 23602568 phosphorylation reaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ABCB1 FBXO15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23465077 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_272790|BIOGRID_272789 prey|bait bait|prey SKP1 FBXO15 MI:0493(in vivo)|MI:0018(two hybrid) 10531037,12665572 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|- MI:0468(hprd)|MI:0468(hprd) HPRD_40576|HPRD_31752 -|- -|- NRF1 FBXO15 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_296873 bait prey FBXO15 CRLS1 MI:0415(enzymatic study)|MI:0415(enzymatic study) 24703837 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_310228|BIOGRID_310229 bait|bait prey|prey FBXO15 SRPK1 MI:0676(tandem affinity purification) 23602568 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0217(phosphorylation reaction) (intact) UniProt_129141 neutral component neutral component UBA7 FBXO15 MI:0004(affinity chromatography technology) 23465077 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_272791 prey bait

PPI - HINT Gene A Gene B PMID Method Quality OS9 FBXO15 26186194 0004 HT CPA6 FBXO15 26186194 0004 HT FBXO15 HINT3 26186194 0004 HT OS9 FBXO15 26186194 0004 HT CPA6 FBXO15 26186194 0004 HT FBXO15 HINT3 26186194 0004 HT FBXO15 SRPK1 23602568 0424 LC FBXO15 CRLS1 24703837,24703837 0415,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8NCQ5 P08183 FBXO15 ABCB1 0.376 23465077 Q8NCQ5 P41226 FBXO15 UBA7 0.21 23465077 Q8NCQ5 Q13438 FBXO15 OS9 0.126 26186194 Q8NCQ5 Q8N4T0 FBXO15 CPA6 0.126 26186194 Q9NQE9 Q8NCQ5 HINT3 FBXO15 0.126 26186194 Q9UJA2 Q8NCQ5 CRLS1 FBXO15 0.523 24703837 Q96SB4 Q8NCQ5 SRPK1 FBXO15 0.033 23602568

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SIAH2 FBXO15 MI:0362 inference MI:1106 pathways database FBXO21 FBXO15 MI:0362 inference MI:1106 pathways database ESRRB FBXO15 MI:0362 inference MI:0461 interaction database ABCB1 FBXO15 MI:0045 experimental interaction detection MI:0461 interaction database UBB FBXO15 MI:0362 inference MI:1106 pathways database UBC FBXO15 MI:0362 inference MI:1106 pathways database TRIM21 FBXO15 MI:0362 inference MI:1106 pathways database CCNF FBXO15 MI:0362 inference MI:1106 pathways database UBA7 FBXO15 MI:0045 experimental interaction detection MI:0461 interaction database UBE2A FBXO15 MI:0362 inference MI:1106 pathways database NR0B1 FBXO15 MI:0362 inference MI:0461 interaction database FBXW4 FBXO15 MI:0362 inference MI:1106 pathways database RBX1 FBXO15 MI:0362 inference MI:1106 pathways database RPS27A FBXO15 MI:0362 inference MI:1106 pathways database UBA52 FBXO15 MI:0362 inference MI:1106 pathways database SKP1 FBXO15 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database POU5F1 FBXO15 MI:0362 inference MI:0461 interaction database POU5F1B FBXO15 MI:0362 inference MI:0461 interaction database TFCP2 FBXO15 MI:0362 inference MI:0461 interaction database CHAF1A FBXO15 MI:0362 inference MI:0461 interaction database SKP2 FBXO15 MI:0362 inference MI:1106 pathways database OS9 FBXO15 MI:0045 experimental interaction detection MI:0461 interaction database CUL1 FBXO15 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database TRIP12 FBXO15 MI:0362 inference MI:1106 pathways database LONRF1 FBXO15 MI:0362 inference MI:1106 pathways database HECTD2 FBXO15 MI:0362 inference MI:1106 pathways database FBXO31 FBXO15 MI:0362 inference MI:1106 pathways database FBXW9 FBXO15 MI:0362 inference MI:1106 pathways database FBXW10 FBXO15 MI:0362 inference MI:1106 pathways database RNF213 FBXO15 MI:0362 inference MI:1106 pathways database FBXL22 FBXO15 MI:0362 inference MI:1106 pathways database FBXL19 FBXO15 MI:0362 inference MI:1106 pathways database FBXW12 FBXO15 MI:0362 inference MI:1106 pathways database RNF19B FBXO15 MI:0362 inference MI:1106 pathways database RNF144B FBXO15 MI:0362 inference MI:1106 pathways database RBBP6 FBXO15 MI:0362 inference MI:1106 pathways database HUWE1 FBXO15 MI:0362 inference MI:1106 pathways database TRIM69 FBXO15 MI:0362 inference MI:1106 pathways database SIAH1 FBXO15 MI:0362 inference MI:1106 pathways database HERC6 FBXO15 MI:0362 inference MI:1106 pathways database UBR2 FBXO15 MI:0362 inference MI:1106 pathways database FBXL14 FBXO15 MI:0362 inference MI:1106 pathways database FBXW8 FBXO15 MI:0362 inference MI:1106 pathways database FBXL16 FBXO15 MI:0362 inference MI:1106 pathways database CPA6 FBXO15 MI:0045 experimental interaction detection MI:0461 interaction database FBXO15 ZNRF1 MI:0362 inference MI:1106 pathways database FBXO15 FBXL13 MI:0362 inference MI:1106 pathways database FBXO15 FBXO22 MI:0362 inference MI:1106 pathways database FBXO15 ZNRF2 MI:0362 inference MI:1106 pathways database FBXO15 FBXO27 MI:0362 inference MI:1106 pathways database FBXO15 FBXO30 MI:0362 inference MI:1106 pathways database FBXO15 RNF217 MI:0362 inference MI:1106 pathways database FBXO15 DTX3L MI:0362 inference MI:1106 pathways database FBXO15 FBXO41 MI:0362 inference MI:1106 pathways database FBXO15 LMO7 MI:0362 inference MI:1106 pathways database FBXO15 MYLIP MI:0362 inference MI:1106 pathways database FBXO15 FBXW7 MI:0362 inference MI:1106 pathways database FBXO15 FBXO32 MI:0362 inference MI:1106 pathways database FBXO15 FBXW5 MI:0362 inference MI:1106 pathways database FBXO15 MIB2 MI:0362 inference MI:1106 pathways database FBXO15 SPSB1 MI:0362 inference MI:1106 pathways database FBXO15 FBXL8 MI:0362 inference MI:1106 pathways database FBXO15 FBXO17 MI:0362 inference MI:1106 pathways database FBXO15 FBXL20 MI:0362 inference MI:1106 pathways database FBXO15 FBXL18 MI:0362 inference MI:1106 pathways database FBXO15 NEDD4L MI:0362 inference MI:1106 pathways database FBXO15 SRPK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO15 RBCK1 MI:0362 inference MI:1106 pathways database FBXO15 FBXL15 MI:0362 inference MI:1106 pathways database FBXO15 FBXO44 MI:0362 inference MI:1106 pathways database FBXO15 UNKL MI:0362 inference MI:1106 pathways database FBXO15 SMURF2 MI:0362 inference MI:1106 pathways database FBXO15 TRIM36 MI:0362 inference MI:1106 pathways database FBXO15 HINT3 MI:0045 experimental interaction detection MI:0461 interaction database FBXO15 FBXO6 MI:0362 inference MI:1106 pathways database FBXO15 RNF19A MI:0362 inference MI:1106 pathways database FBXO15 RLIM MI:0362 inference MI:1106 pathways database FBXO15 FBXL12 MI:0362 inference MI:1106 pathways database FBXO15 TFCP2L1 MI:0362 inference MI:0461 interaction database FBXO15 UBP1 MI:0362 inference MI:0461 interaction database FBXO15 FBXO40 MI:0362 inference MI:1106 pathways database FBXO15 HERC5 MI:0362 inference MI:1106 pathways database FBXO15 CRLS1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO15 FBXL7 MI:0362 inference MI:1106 pathways database FBXO15 FBXO2 MI:0362 inference MI:1106 pathways database FBXO15 FBXO10 MI:0362 inference MI:1106 pathways database FBXO15 FBXO9 MI:0362 inference MI:1106 pathways database FBXO15 FBXL5 MI:0362 inference MI:1106 pathways database FBXO15 FBXL4 MI:0362 inference MI:1106 pathways database FBXO15 FBXW11 MI:0362 inference MI:1106 pathways database FBXO15 FBXO4 MI:0362 inference MI:1106 pathways database FBXO15 FBXL21 MI:0362 inference MI:1106 pathways database FBXO15 FBXL3 MI:0362 inference MI:1106 pathways database FBXO15 FBXW2 MI:0362 inference MI:1106 pathways database FBXO15 BTRC MI:0362 inference MI:1106 pathways database FBXO15 FBXO7 MI:0362 inference MI:1106 pathways database FBXO15 RNF115 MI:0362 inference MI:1106 pathways database FBXO15 RNF114 MI:0362 inference MI:1106 pathways database FBXO15 WSB1 MI:0362 inference MI:1106 pathways database