Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 6651728 rs1556036 C T rs1556036 1.06E-04 Multiple complex diseases HPOID:0000118 NA G UTR-3 GWASdb_trait 1 6651728 rs1556036 C T rs1556036 4.54E-05 Heart Rate HPOID:0005150|HPOID:0001645|HPOID:0001644|HPOID:0011704|HPOID:0005110 DOID:10273 G UTR-3 GWASdb_trait 1 6657355 rs4587589 C T rs4587589 1.07E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs201171 1 6651093 6651093 UTR3 0.433451 0.363059990765404 GWAS of prostate cancer rs1556036 1 6651728 6651728 UTR3 0.232155 0.634221958351348 GWAS of prostate cancer rs12028517 1 6661732 6661732 intronic 0.184921 0.7330137666869749 GWAS of prostate cancer rs6674407 1 6662913 6662913 UTR5 0.172945 0.762091989323507

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000162413.16 KLHL21 616262