PTM - CPLM Gene Name UniProt ID Type Position Code Ddi2 A2ADY9 Ubiquitination 67 K Ddi2 A2ADY9 Ubiquitination 77 K Ddi2 A2ADY9 Ubiquitination 153 K Ddi2 A2ADY9 Ubiquitination 170 K Ddi2 A2ADY9 Ubiquitination 205 K Ddi2 A2ADY9 Ubiquitination 283 K Ddi2 A2ADY9 Ubiquitination 289 K Ddi2 A2ADY9 Ubiquitination 338 K Ddi2 A2ADY9 Ubiquitination 389 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Ddi2 A2ADY9 115 T Mus musculus(Mouse) Ddi2 A2ADY9 120 S Mus musculus(Mouse) Ddi2 A2ADY9 121 S Mus musculus(Mouse) Ddi2 A2ADY9 127 S Mus musculus(Mouse) Ddi2 A2ADY9 128 S Mus musculus(Mouse) Ddi2 A2ADY9 194 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA A2ADY9 T115-p Phosphorylation QQRQLPRtQAQHssP A2ADY9 S120-p Phosphorylation PRtQAQHssPGEMAS A2ADY9 S121-p Phosphorylation RtQAQHssPGEMASs A2ADY9 S128-p Phosphorylation sPGEMASsPQGLDNP A2ADY9 S150-p Phosphorylation LANPHELsLLkERNP A2ADY9 S194-p Phosphorylation QERIRLFsADPFDLE A2ADY9 K67-ub Ubiquitination SLASYGLkDGDVVIL A2ADY9 K77-ub Ubiquitination DVVILRQkENADPRP A2ADY9 K153-ub Ubiquitination PHELsLLkERNPPLA A2ADY9 K170-ub Ubiquitination LLSGDLEkFSRVLVE A2ADY9 K205-ub Ubiquitination FDLEAQAkIEEDIRQ A2ADY9 K283-ub Ubiquitination RRWAGIAkGVGTQkI A2ADY9 K289-ub Ubiquitination AkGVGTQkIIGRVHL A2ADY9 K338-ub Ubiquitination QCSIDLKkNVLVIGT A2ADY9 K389-ub Ubiquitination ELAEAIQkSAEDAER

PTM - dbPTM UniProt ID Position Code Type Resources References A2ADY9 120 S Phosphorylation Swiss-Prot 1010711 17242355 A2ADY9 121 S Phosphorylation Swiss-Prot 1010711 17242355 A2ADY9 128 S Phosphorylation Swiss-Prot 1010711 17242355 A2ADY9 120 S Phosphorylation PhosphoELM.10011 17242355 A2ADY9 121 S Phosphorylation PhosphoELM.10011 17242355 A2ADY9 128 S Phosphorylation PhosphoELM.10011 17242355 A2ADY9 125 M Oxidation SysPTM 1.1 17242355 A2ADY9 120 S Phosphorylation SysPTM 1.1 17242355 A2ADY9 121 S Phosphorylation SysPTM 1.1 17242355 A2ADY9 128 S Phosphorylation SysPTM 1.1 18846507;17242355

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type A2ADY9 128 S 17242355 HTP Phosphorylation A2ADY9 120 S 17242355 HTP Phosphorylation A2ADY9 121 S 17242355 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs A2ADY9 121 Phosphoserine 17242355;21183079 A2ADY9 128 Phosphoserine 17242355;21183079 A2ADY9 194 Phosphoserine 21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Ddi2 IPI00608021 S 120 RTQAQHpSSPGEMA phosphorylation Ddi2 IPI00608021 S 121 TQAQHSpSPGEMAS phosphorylation Ddi2 IPI00608021 S 128 PGEMASpSPQGLDN phosphorylation Ddi2 IPI00608021 S 194 ERIRLFpSADPFDL phosphorylation Ddi2 IPI00608021 T 115 QRQLPRpTQAQHSS phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Ddi2 Mus musculus (Mouse) 153; 389; 170; 289; 338; 205; 77; 67; 283 "153,HELSLLKERNPPL; 389,LAEAIQKSAEDAE; 170,LSGDLEKFSRVLV; 289,KGVGTQKIIGRVH; 338,CSIDLKKNVLVIG; 205,DLEAQAKIEEDIR; 77,VVILRQKENADPR; 67,LASYGLKDGDVVI; 283,RWAGIAKGVGTQK" 153:22790023; 389:22790023; 170:22790023; 289:22790023; 338:22790023; 205:22790023; 77:22790023; 67:22790023; 283:22790023