iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117166

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01027332

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008456.1	ENSTGUT00000008848.1	ENSTGUP00000008755.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.90e-102	340.6	446	784

Active Site

Position(s)	Description	Evidence
752	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           k+dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G l+g+a++++  ld+
   Q: 446  KADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSQCHWFSSFKC-----DNYSEFRLVGALMGLAVYNSITLDI 529
           789***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgkk..............lsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+ +              ++l+dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++Lkp+G++ipV
   Q: 530  RFPPCCYKKLLSPPivpcdhntlvgicgVTLDDLFQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGVIKSYNLKPNGDKIPV 616
           ************9555566666666666**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn N++eYv+l+v++ l+++i +q++af+ Gf++v+    l l+++ee+e+l+cG++e+d+++l++ t+y+ gy++++ +i++Fw+v+ 
   Q: 617  TNRNRKEYVQLYVDFLLNRSIYKQFAAFYYGFHSVCASYALLLLRPEEVEILVCGSPELDMSALQRSTQYE-GYQKTDMTIRYFWDVVL 704
           **********************************************************************5.5**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +fs + +k++L+F+Tgs+r+P+gG+a+l+   f i++ ++s+++lP ++TCfn+L+LP+Y++k++lk+kL++ i++++gF+l+
   Q: 705  GFSLDLQKKLLHFATGSDRVPVGGMADLN---FKISRsETSTNWLPVAHTCFNQLCLPPYKNKKELKQKLIIGISNAEGFGLE 784
           *****************************...6666648888**************************************985 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

ELSQGSAAAP SAQEGGEEEE EEEEGEKEKE KEKEKEKEGE KLPPIPSASA AAVGGLEEGA 60
KNQFSTFSNF ITTINQKKEG IGNRNSPTQL VIPNIKNGKD LPPLCLDVRQ KQRMSVDALP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCTGAGCC AGGGCAGCGC CGCGGCCCCG TCAGCCCAGG AGGGCGGCGA GGAGGAGGAA 60
GAAGAGGAAG AAGGGGAGAA GGAAAAAGAA AAGGAAAAAG AAAAGGAAAA GGAGGGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	85.15	0.00e+00	1304.00
IUUC-Apl-003589	Anas platyrhynchos	95.90	0.00e+00	1439.00
IUUC-Aca-004350	Anolis carolinensis	82.61	0.00e+00	1244.00
IUUC-Ago-007908	Ashbya gossypii	35.39	4.00e-79	289.00
IUUC-Acl-008288	Aspergillus clavatus	34.87	2.00e-92	333.00
IUUC-Afl-008402	Aspergillus flavus	33.67	3.00e-85	309.00
IUUC-Afu-008762	Aspergillus fumigatus	33.17	3.00e-88	320.00
IUUC-Ani-009176	Aspergillus nidulans	34.55	1.00e-86	314.00
IUUC-Ang-009791	Aspergillus niger	34.58	3.00e-87	316.00
IUUC-Aor-009921	Aspergillus oryzae	33.50	1.00e-84	307.00
IUUC-Ate-010295	Aspergillus terreus	34.98	1.00e-95	344.00
IUUC-Ame-010660	Astyanax mexicanus	82.27	5.00e-152	529.00
IUUC-Bgr-011981	Blumeria graminis	37.62	3.00e-88	320.00
IUUC-Bta-012945	Bos taurus	83.92	0.00e+00	1274.00
IUUC-Bci-013697	Botrytis cinerea	37.23	3.00e-77	283.00
IUUC-Cja-019263	Callithrix jacchus	82.80	0.00e+00	1253.00
IUUC-Cfa-020486	Canis familiaris	88.06	0.00e+00	1191.00
IUUC-Cpo-021755	Cavia porcellus	84.37	0.00e+00	1298.00
IUUC-Csa-023814	Chlorocebus sabaeus	83.17	0.00e+00	1192.00
IUUC-Cho-024980	Choloepus hoffmanni	69.19	0.00e+00	1007.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.10	1.00e-91	331.00
IUUC-Dre-028551	Danio rerio	74.56	0.00e+00	1127.00
IUUC-Dno-029497	Dasypus novemcinctus	84.03	0.00e+00	1165.00
IUUC-Dor-030867	Dipodomys ordii	72.70	0.00e+00	1052.00
IUUC-Dse-031239	Dothistroma septosporum	28.78	1.00e-86	314.00
IUUC-Ete-032902	Echinops telfairi	71.76	0.00e+00	1068.00
IUUC-Eca-033678	Equus caballus	84.52	0.00e+00	1276.00
IUUC-Eeu-035262	Erinaceus europaeus	71.14	0.00e+00	967.00
IUUC-Fca-035590	Felis catus	85.34	0.00e+00	1308.00
IUUC-Fal-037123	Ficedula albicollis	94.65	0.00e+00	1429.00
IUUC-Fox-037941	Fusarium oxysporum	40.70	9.00e-97	348.00
IUUC-Fso-038388	Fusarium solani	40.87	7.00e-99	355.00
IUUC-Gmo-039553	Gadus morhua	66.77	0.00e+00	854.00
IUUC-Ggr-040110	Gaeumannomyces graminis	39.68	5.00e-93	335.00
IUUC-Gga-040406	Gallus gallus	94.59	0.00e+00	1453.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.80	0.00e+00	1093.00
IUUC-Ggo-045504	Gorilla gorilla	82.86	0.00e+00	1262.00
IUUC-Hsa-045786	Homo sapiens	83.31	0.00e+00	1267.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	80.12	0.00e+00	1134.00
IUUC-Kpa-049152	Komagataella pastoris	33.27	1.00e-72	267.00
IUUC-Lch-049824	Latimeria chalumnae	80.61	0.00e+00	1114.00
IUUC-Loc-052173	Lepisosteus oculatus	78.09	0.00e+00	1175.00
IUUC-Laf-054017	Loxodonta africana	86.73	0.00e+00	1235.00
IUUC-Mcc-055713	Macaca mulatta	83.33	0.00e+00	1244.00
IUUC-Meu-056212	Macropus eugenii	67.28	2.00e-110	392.00
IUUC-Mor-057045	Magnaporthe oryzae	37.27	6.00e-85	309.00
IUUC-Mla-059187	Melampsora laricipopulina	43.95	4.00e-87	314.00
IUUC-Mga-059884	Meleagris gallopavo	86.10	0.00e+00	1264.00
IUUC-Mmr-061344	Microcebus murinus	84.36	0.00e+00	1269.00
IUUC-Mdo-062653	Monodelphis domestica	83.58	0.00e+00	1262.00
IUUC-Mmu-063775	Mus musculus	82.66	0.00e+00	1194.00
IUUC-Mpu-066069	Mustela putorius furo	87.14	0.00e+00	1206.00
IUUC-Mlu-067925	Myotis lucifugus	84.66	0.00e+00	1265.00
IUUC-Nfi-068439	Neosartorya fischeri	33.33	2.00e-88	320.00
IUUC-Ncr-068903	Neurospora crassa	38.15	6.00e-90	325.00
IUUC-Nle-070046	Nomascus leucogenys	83.00	0.00e+00	1274.00
IUUC-Opr-071085	Ochotona princeps	74.50	7.00e-130	457.00
IUUC-Ont-072126	Oreochromis niloticus	73.49	0.00e+00	1156.00
IUUC-Oan-072933	Ornithorhynchus anatinus	86.55	0.00e+00	1147.00
IUUC-Ocu-073800	Oryctolagus cuniculus	87.29	0.00e+00	1197.00
IUUC-Ola-086988	Oryzias latipes	75.84	0.00e+00	1106.00
IUUC-Oga-088117	Otolemur garnettii	87.41	0.00e+00	1042.00
IUUC-Oar-089371	Ovis aries	84.38	0.00e+00	1251.00
IUUC-Ptr-090551	Pan troglodytes	82.20	0.00e+00	1218.00
IUUC-Pan-092067	Papio anubis	83.78	0.00e+00	1250.00
IUUC-Psi-092963	Pelodiscus sinensis	87.21	0.00e+00	1279.00
IUUC-Pfo-096562	Poecilia formosa	70.59	0.00e+00	1105.00
IUUC-Pab-098680	Pongo abelii	83.31	0.00e+00	1269.00
IUUC-Pca-100986	Procavia capensis	70.17	0.00e+00	850.00
IUUC-Pva-102219	Pteropus vampyrus	70.43	0.00e+00	951.00
IUUC-Pgr-103315	Puccinia graminis	35.90	1.00e-91	330.00
IUUC-Ptt-103736	Puccinia triticina	41.33	3.00e-91	329.00
IUUC-Rno-105270	Rattus norvegicus	81.60	0.00e+00	1196.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.84	1.00e-68	254.00
IUUC-Sha-106819	Sarcophilus harrisii	85.48	0.00e+00	1309.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.69	2.00e-81	296.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	36.65	3.00e-79	290.00
IUUC-Sar-113134	Sorex araneus	76.44	0.00e+00	1110.00
IUUC-Ssc-115441	Sus scrofa	84.75	0.00e+00	1267.00
IUUC-Tsy-118898	Tarsius syrichta	72.85	0.00e+00	997.00
IUUC-Tre-122108	Trichoderma reesei	37.70	3.00e-85	310.00
IUUC-Tvi-122644	Trichoderma virens	38.76	9.00e-91	328.00
IUUC-Tme-127004	Tuber melanosporum	36.39	4.00e-98	353.00
IUUC-Tbe-127292	Tupaia belangeri	68.49	0.00e+00	944.00
IUUC-Ttr-128352	Tursiops truncatus	81.10	0.00e+00	1211.00
IUUC-Vda-129969	Verticillium dahliae	39.34	9.00e-88	318.00
IUUC-Vpa-130218	Vicugna pacos	82.19	0.00e+00	901.00
IUUC-Xtr-132594	Xenopus tropicalis	77.39	0.00e+00	1150.00
IUUC-Xma-134157	Xiphophorus maculatus	74.50	0.00e+00	1023.00
IUUC-Yli-134470	Yarrowia lipolytica	34.88	3.00e-75	276.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence