iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aor-010085

Ensembl Protein ID

BAE65301

UniProt Accession

Q2TZG4; PFS2_ASPOR

Genbank Protein ID

BAE65301.1

Protein Name

Polyadenylation factor subunit 2

Genbank Nucleotide ID

AP007171

Gene Name

pfs2; AO090011000862

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AO090011000862	BAE65301	BAE65301

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-34	115.5	230	263
UBD/Beta-Prp	2.30e-55	187.2	95	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           +v ++++ ++ +llvsGs D+++k WD+rt ++l
   Q: 230  DVKSCDWhPTkGLLVSGSKDHQVKFWDPRTARCL 263
           5999****989********************997 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           g+ k++it+v ++p+++ l+tg+ +g   +w+ t  ++     + + + +a+vt++ +s++ ++l++g++ + ik w ++ +    +  +h d v++l++s
   Q: 95   GKSKKPITVVRWTPEGRRLLTGGHTGEFMLWNGTAFNFetvmDAHYDQLQAGVTSLAWSHSHDWLISGGQKGDIKYWRPNFNNVETIDDAHHDAVRDLAWS 195
           67799****************************9999944422333334567*************************66544444444588********** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfds.ngkelvsgsldgt 203
           ps+ k++s+s+d t++++d  +++    +l+gh+  v +  +hp++ llvsGs+D +v++Wd +t+++l+tl + h++ v+ + f++ n++ l++ s+d+t
   Q: 196  PSDTKFLSASDDTTLKIFDFTSRTADT-VLTGHNWDVKSCDWHPTKGLLVSGSKDHQVKFWDPRTARCLTTLHS-HKNTVTATRFSRvNQNLLATSSRDQT 294
           **************************9.*********************************************9.*********99846688999****** PP
   S: 204  vklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
            +++dl+  + + +l+gh+++v+s+  +  ++ ++ +gs+Dgs++ +
   Q: 295  ARVFDLRMMRDICILRGHEKPVSSLTWHpIHSSLISTGSEDGSLYHY 341
           *******9999*****************77888888888****9877 PP

Organism

Aspergillus oryzae

Functional Description
(View)

Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

Protein Sequence
(Fasta)

MAFYDDSGAD SQPFGRPQKP YEGGIVGPRR PRLVTDYGSS LVQWMRTRRP RYKGGHRMET 60
ERPSASYIVD MLPPLARIHS PVDTIPVRHL HQSIGKSKKP ITVVRWTPEG RRLLTGGHTG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCATTTT ACGACGACTC TGGGGCCGAC TCCCAGCCAT TTGGAAGACC TCAAAAACCC 60
TATGAGGGTG GAATTGTGGG ACCACGGCGA CCACGTACGT TTATTTCATT GATTTGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0000790--C:nuclear chromatin
GO:0007059--P:chromosome segregation
GO:0031124--P:mRNA 3'-end processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	39.70	2.00e-87	315.00
IUUC-Aml-001363	Ailuropoda melanoleuca	40.50	3.00e-91	328.00
IUUC-Atr-003030	Amborella trichopoda	41.18	4.00e-92	330.00
IUUC-Apl-003409	Anas platyrhynchos	40.15	1.00e-89	323.00
IUUC-Aca-004694	Anolis carolinensis	40.35	4.00e-91	328.00
IUUC-Aly-006063	Arabidopsis lyrata	38.00	5.00e-91	327.00
IUUC-Ath-006583	Arabidopsis thaliana	42.40	2.00e-89	321.00
IUUC-Ago-007805	Ashbya gossypii	43.21	1.00e-86	311.00
IUUC-Acl-008075	Aspergillus clavatus	85.23	0.00e+00	978.00
IUUC-Afl-008582	Aspergillus flavus	99.82	0.00e+00	1033.00
IUUC-Afu-008817	Aspergillus fumigatus	83.17	0.00e+00	788.00
IUUC-Ani-009391	Aspergillus nidulans	84.96	0.00e+00	818.00
IUUC-Ang-009750	Aspergillus niger	94.67	0.00e+00	672.00
IUUC-Ate-010397	Aspergillus terreus	89.59	0.00e+00	996.00
IUUC-Ame-010741	Astyanax mexicanus	41.67	2.00e-56	212.00
IUUC-Bgr-012169	Blumeria graminis	66.04	4.00e-147	513.00
IUUC-Bta-013265	Bos taurus	40.50	4.00e-91	328.00
IUUC-Bci-013762	Botrytis cinerea	64.76	5.00e-170	588.00
IUUC-Bdi-014849	Brachypodium distachyon	41.44	2.00e-93	334.00
IUUC-Bol-015325	Brassica oleracea	40.59	2.00e-92	331.00
IUUC-Bra-017064	Brassica rapa	41.56	1.00e-93	335.00
IUUC-Cel-018378	Caenorhabditis elegans	40.36	1.00e-86	312.00
IUUC-Cja-019547	Callithrix jacchus	40.50	2.00e-91	328.00
IUUC-Cfa-020031	Canis familiaris	40.50	3.00e-91	328.00
IUUC-Cpo-021554	Cavia porcellus	40.45	6.00e-91	327.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	34.72	2.00e-52	198.00
IUUC-Csa-023146	Chlorocebus sabaeus	40.25	6.00e-91	327.00
IUUC-Cho-024679	Choloepus hoffmanni	40.83	2.00e-83	302.00
IUUC-Cin-025415	Ciona intestinalis	38.60	4.00e-81	294.00
IUUC-Csv-026003	Ciona savignyi	37.59	2.00e-78	284.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	65.57	3.00e-159	553.00
IUUC-Cne-026983	Cryptococcus neoformans	40.00	2.00e-81	295.00
IUUC-Cme-027147	Cyanidioschyzon merolae	40.91	8.00e-86	308.00
IUUC-Dre-028545	Danio rerio	38.72	3.00e-89	322.00
IUUC-Dno-029677	Dasypus novemcinctus	40.50	2.00e-91	329.00
IUUC-Dse-031371	Dothistroma septosporum	55.15	2.00e-131	460.00
IUUC-Dme-031663	Drosophila melanogaster	39.48	3.00e-89	320.00
IUUC-Ete-032511	Echinops telfairi	33.25	6.00e-67	248.00
IUUC-Eca-034152	Equus caballus	40.50	3.00e-91	328.00
IUUC-Eeu-034560	Erinaceus europaeus	27.46	2.00e-21	96.30
IUUC-Fca-035820	Felis catus	40.50	2.00e-91	328.00
IUUC-Fox-037958	Fusarium oxysporum	63.70	6.00e-165	572.00
IUUC-Fso-038162	Fusarium solani	64.83	1.00e-163	567.00
IUUC-Gmo-039708	Gadus morhua	39.70	5.00e-90	323.00
IUUC-Ggr-040031	Gaeumannomyces graminis	64.16	1.00e-158	550.00
IUUC-Gga-040963	Gallus gallus	40.35	3.00e-91	328.00
IUUC-Gac-041541	Gasterosteus aculeatus	38.42	3.00e-86	311.00
IUUC-Gma-044352	Glycine max	41.11	4.00e-95	340.00
IUUC-Ggo-045564	Gorilla gorilla	40.50	3.00e-91	328.00
IUUC-Hsa-045833	Homo sapiens	40.50	3.00e-91	328.00
IUUC-Hvu-047848	Hordeum vulgare	39.66	5.00e-67	246.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	40.50	4.00e-91	328.00
IUUC-Kpa-049308	Komagataella pastoris	43.55	5.00e-102	362.00
IUUC-Lch-050525	Latimeria chalumnae	40.74	1.00e-91	329.00
IUUC-Lpe-051364	Leersia perrieri	34.67	3.00e-74	270.00
IUUC-Loc-052696	Lepisosteus oculatus	40.25	2.00e-90	325.00
IUUC-Lma-052951	Leptosphaeria maculans	62.01	7.00e-149	518.00
IUUC-Laf-053653	Loxodonta africana	40.50	7.00e-91	327.00
IUUC-Mcc-055797	Macaca mulatta	40.50	2.00e-91	328.00
IUUC-Meu-056331	Macropus eugenii	44.89	2.00e-73	269.00
IUUC-Mor-057168	Magnaporthe oryzae	63.70	3.00e-162	563.00
IUUC-Mpo-057510	Magnaporthe poae	60.84	2.00e-96	343.00
IUUC-Mtr-058032	Medicago truncatula	39.37	3.00e-92	330.00
IUUC-Mla-058852	Melampsora laricipopulina	42.93	2.00e-98	350.00
IUUC-Mga-059311	Meleagris gallopavo	40.50	3.00e-91	328.00
IUUC-Mvi-060544	Microbotryum violaceum	44.27	9.00e-95	338.00
IUUC-Mmr-061143	Microcebus murinus	40.50	3.00e-91	328.00
IUUC-Mdo-061977	Monodelphis domestica	40.50	3.00e-91	328.00
IUUC-Mmu-063922	Mus musculus	40.50	3.00e-91	328.00
IUUC-Mac-064961	Musa acuminata	40.19	8.00e-95	339.00
IUUC-Mpu-066079	Mustela putorius furo	42.21	3.00e-85	308.00
IUUC-Mlu-067247	Myotis lucifugus	40.50	2.00e-91	328.00
IUUC-Nfi-068255	Neosartorya fischeri	88.26	0.00e+00	849.00
IUUC-Ncr-068909	Neurospora crassa	66.06	1.00e-165	574.00
IUUC-Nle-068994	Nomascus leucogenys	40.50	2.00e-91	328.00
IUUC-Opr-071079	Ochotona princeps	40.50	2.00e-91	329.00
IUUC-Ont-071971	Oreochromis niloticus	40.25	2.00e-90	325.00
IUUC-Oan-073135	Ornithorhynchus anatinus	42.09	3.00e-90	325.00
IUUC-Ocu-073982	Oryctolagus cuniculus	40.50	4.00e-91	328.00
IUUC-Oba-075297	Oryza barthii	33.68	1.00e-76	278.00
IUUC-Obr-076641	Oryza brachyantha	37.24	7.00e-91	326.00
IUUC-Ogl-077539	Oryza glaberrima	40.00	4.00e-67	246.00
IUUC-Ogu-078807	Oryza glumaepatula	33.68	1.00e-76	278.00
IUUC-Oin-079229	Oryza indica	39.95	8.00e-91	326.00
IUUC-Olo-080371	Oryza longistaminata	35.73	3.00e-76	277.00
IUUC-Ome-081149	Oryza meridionalis	35.73	1.00e-75	275.00
IUUC-Oni-082970	Oryza nivara	35.73	2.00e-76	278.00
IUUC-Opu-083415	Oryza punctata	35.14	4.00e-75	273.00
IUUC-Oru-085236	Oryza rufipogon	35.73	1.00e-76	279.00
IUUC-Ola-087421	Oryzias latipes	38.63	3.00e-89	320.00
IUUC-Olu-087821	Ostreococcus lucimarinus	37.11	3.00e-78	283.00
IUUC-Oga-088132	Otolemur garnettii	40.50	3.00e-91	328.00
IUUC-Oar-089513	Ovis aries	40.50	3.00e-91	328.00
IUUC-Ptr-090717	Pan troglodytes	40.50	3.00e-91	328.00
IUUC-Pan-092108	Papio anubis	40.50	2.00e-91	328.00
IUUC-Psi-093892	Pelodiscus sinensis	40.50	7.00e-91	327.00
IUUC-Pma-094561	Petromyzon marinus	40.05	1.00e-91	329.00
IUUC-Pno-094943	Phaeosphaeria nodorum	58.46	3.00e-154	536.00
IUUC-Ppa-095359	Physcomitrella patens	42.72	2.00e-97	347.00
IUUC-Pfo-096516	Poecilia formosa	39.28	3.00e-88	318.00
IUUC-Pab-097759	Pongo abelii	40.50	2.00e-91	329.00
IUUC-Pop-099553	Populus trichocarpa	40.59	5.00e-94	336.00
IUUC-Ppe-101957	Prunus persica	41.85	4.00e-95	340.00
IUUC-Pva-102918	Pteropus vampyrus	40.50	5.00e-91	327.00
IUUC-Pgr-103594	Puccinia graminis	43.87	2.00e-100	357.00
IUUC-Ptt-103879	Puccinia triticina	46.27	1.00e-88	318.00
IUUC-Pte-104419	Pyrenophora teres	61.00	5.00e-162	562.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	62.04	5.00e-150	522.00
IUUC-Rno-105838	Rattus norvegicus	40.50	2.00e-91	329.00
IUUC-Sce-106331	Saccharomyces cerevisiae	43.14	5.00e-84	302.00
IUUC-Sha-107435	Sarcophilus harrisii	40.25	9.00e-92	330.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	45.37	2.00e-105	374.00
IUUC-Spo-108163	Schizosaccharomyces pombe	46.86	7.00e-109	385.00
IUUC-Smo-109602	Selaginella moellendorffii	43.25	4.00e-94	336.00
IUUC-Sit-109729	Setaria italica	40.20	3.00e-90	324.00
IUUC-Sly-111679	Solanum lycopersicum	39.30	4.00e-94	337.00
IUUC-Sar-113157	Sorex araneus	40.50	6.00e-91	327.00
IUUC-Sbi-114853	Sorghum bicolor	39.12	2.00e-89	321.00
IUUC-Sre-115085	Sporisorium reilianum	41.27	5.00e-84	303.00
IUUC-Ssc-116286	Sus scrofa	40.15	4.00e-89	321.00
IUUC-Tgu-117219	Taeniopygia guttata	40.50	3.00e-91	328.00
IUUC-Tru-117550	Takifugu rubripes	38.95	3.00e-89	320.00
IUUC-Tsy-119294	Tarsius syrichta	40.50	2.00e-91	328.00
IUUC-Tni-120561	Tetraodon nigroviridis	40.25	7.00e-90	323.00
IUUC-Tca-121347	Theobroma cacao	41.10	2.00e-93	335.00
IUUC-Tre-122018	Trichoderma reesei	64.88	3.00e-160	556.00
IUUC-Tvi-122413	Trichoderma virens	64.16	1.00e-158	551.00
IUUC-Tae-123904	Triticum aestivum	40.69	6.00e-93	333.00
IUUC-Tme-127077	Tuber melanosporum	53.96	2.00e-129	454.00
IUUC-Tbe-127744	Tupaia belangeri	30.27	1.00e-43	170.00
IUUC-Ttr-128777	Tursiops truncatus	34.05	1.00e-65	243.00
IUUC-Uma-129568	Ustilago maydis	43.63	1.00e-82	298.00
IUUC-Vda-129834	Verticillium dahliae	61.85	1.00e-156	544.00
IUUC-Vvi-131360	Vitis vinifera	41.35	8.00e-94	336.00
IUUC-Xtr-132630	Xenopus tropicalis	41.00	6.00e-92	331.00
IUUC-Xma-133665	Xiphophorus maculatus	39.61	4.00e-90	324.00
IUUC-Yli-134556	Yarrowia lipolytica	39.78	5.00e-92	329.00
IUUC-Zma-135787	Zea mays	39.70	7.00e-91	326.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence