iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025302

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01001977

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000003638.3	ENSCINT00000025058.2	ENSCINP00000024812.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-53	182.5	58	585

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gN+C++  v+Q+L++ip +r+ +l+    +   +ln+e++++++ +l+++l+ lf+ + +s+k+  +p + +++l+++ +  s
   Q: 58   VGLKNVGNSCWFSVVVQSLFHIPIFRNIILKfgptEIDPSLNAEEKTKRNLRLMQELRCLFALMITSNKSFLDPIKCVNILQEAFQTKS 146
           6******************************9999788888999999****************************************** PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde................................aeekkkkknksli 142
           + +qqD++Ef+++lld le+++ +   +++++e++ +k++ ++                                 ++    ++++ l 
   Q: 147  SDSQQDVSEFTHMLLDWLEDAFRH--IQETTQENDRRKERNNEFnitsaddigvisdlrgpqkplcnpvqelfygtSKTVGVNRHEFLY 233
           **********************44..233333322222222222556666789998666666666666666666654444455555555 PP
   S: 143  sdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLi 231
            + F++ l+ ++      +++++e +f  l+l v+g++     +l+++Le  t++         +ce+ ++     ++++++klP++L+
   Q: 234  FEKFGIYLEYSLFFHGYLTSTKQEHTFGILPLCVEGHK-----NLHESLEYATAK--------AHCETSQN----GQEVWFTKLPPILT 305
           66666666677777777777777777777777777777.....677777655543........34555544....558*********** PP
   S: 232  lhLkRfsfseeqksrekinkkvefpleLdlspfcts.....peekqke......................................... 274
           ++L+Rf+f+++ +++eki++++ fp  + ++++++s     +                                               
   Q: 306  FQLSRFQFNQAIGKPEKIHNRLIFPSLFYMDRYMESnaqktR-----Arreeikqlreelselklnlnqlsnftaneksyhvaellsic 389
           ************************************444440.....355566666666666666666666666666666666666666 PP
   S: 275  ......................................................................................... 274
                                                                                                    
   Q: 390  aeyatskssssnmdgnascgrrlrkfllivsilsvkkfgfcrifthdsakteslskslirpnkfgkpklryitnnvfifkrlfatdnlk 478
           66666666667777777777777777777777777777777777777777777778888888888888888888888888888888888 PP
   S: 275  .................................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.. 327
                                            +  Y+L+av+vH+G++  GHY+ay+k+  +++Wl+f+D  Vte + ++  +++   
   Q: 479  yccssitfhadirekieeiqmtidkmfddpnerCFPYSLHAVLVHQGQALAGHYWAYIKDyVNRRWLKFNDVAVTEETYDQLTSDSIgg 567
           888888888888888888888888888888888***************************44555************99999997779* PP
   S: 328  ..........staYvlfY 335
                     ++aY+l+Y
   Q: 568  vhsyrfygnsASAYCLIY 585
           ****************99 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MEPGTSSSVE HLEGDDLARA LAESIADIQS RQPISGDASH RHKKDPHNLL RISKNWPVGL 60
KNVGNSCWFS VVVQSLFHIP IFRNIILKFG PTEIDPSLNA EEKTKRNLRL MQELRCLFAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCCAGCAA AACCTTAGGC TCTGTAGAAC GAAATGTAAA ATAAAAGGTT ATAGATCCAT 60
AAAACCACTA TATTTGTAAT TAAACCACTT TTGAAAAAGT AATACTGTTC CTTCTGAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	37.73	3.00e-96	345.00
IUUC-Apl-004030	Anas platyrhynchos	37.63	4.00e-97	348.00
IUUC-Aca-004741	Anolis carolinensis	35.84	1.00e-92	333.00
IUUC-Ago-007865	Ashbya gossypii	46.77	4.00e-08	53.10
IUUC-Acl-008164	Aspergillus clavatus	35.23	8.00e-10	58.50
IUUC-Afl-008717	Aspergillus flavus	30.00	1.00e-09	58.20
IUUC-Afu-008871	Aspergillus fumigatus	36.36	4.00e-10	59.30
IUUC-Ani-009503	Aspergillus nidulans	31.82	5.00e-10	58.90
IUUC-Ang-009577	Aspergillus niger	23.10	3.00e-15	76.30
IUUC-Aor-009928	Aspergillus oryzae	28.89	3.00e-09	56.20
IUUC-Ate-010275	Aspergillus terreus	34.02	5.00e-10	58.90
IUUC-Ame-010624	Astyanax mexicanus	37.18	1.00e-53	203.00
IUUC-Bgr-011993	Blumeria graminis	40.54	6.00e-09	55.80
IUUC-Bta-013166	Bos taurus	37.17	2.00e-95	343.00
IUUC-Cel-018346	Caenorhabditis elegans	26.36	8.00e-20	91.70
IUUC-Cja-019150	Callithrix jacchus	37.33	3.00e-95	342.00
IUUC-Cfa-020649	Canis familiaris	37.82	1.00e-96	347.00
IUUC-Cpo-021807	Cavia porcellus	37.17	2.00e-95	343.00
IUUC-Csa-023388	Chlorocebus sabaeus	37.25	2.00e-94	339.00
IUUC-Cho-024717	Choloepus hoffmanni	38.83	4.00e-32	132.00
IUUC-Csv-025911	Ciona savignyi	62.48	5.00e-178	616.00
IUUC-Cgl-026575	Colletotrichum gloeosporioides	52.50	6.00e-08	52.00
IUUC-Cme-027167	Cyanidioschyzon merolae	28.79	2.00e-14	73.90
IUUC-Dre-028016	Danio rerio	37.00	2.00e-93	335.00
IUUC-Dno-029495	Dasypus novemcinctus	36.97	2.00e-94	339.00
IUUC-Dor-030955	Dipodomys ordii	33.92	3.00e-77	282.00
IUUC-Ete-032828	Echinops telfairi	35.09	9.00e-64	237.00
IUUC-Eca-034300	Equus caballus	34.85	5.00e-84	304.00
IUUC-Eeu-034458	Erinaceus europaeus	35.66	3.00e-86	311.00
IUUC-Fca-035876	Felis catus	37.17	5.00e-97	347.00
IUUC-Fal-036762	Ficedula albicollis	38.73	1.00e-97	348.00
IUUC-Gmo-039490	Gadus morhua	38.12	7.00e-96	344.00
IUUC-Gga-040817	Gallus gallus	37.63	7.00e-97	347.00
IUUC-Gac-042473	Gasterosteus aculeatus	37.29	5.00e-92	331.00
IUUC-Ggo-044939	Gorilla gorilla	37.33	4.00e-95	342.00
IUUC-Hsa-046204	Homo sapiens	37.33	3.00e-95	342.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	32.30	4.00e-26	111.00
IUUC-Kpa-049349	Komagataella pastoris	30.36	2.00e-08	53.50
IUUC-Lch-049572	Latimeria chalumnae	37.35	5.00e-92	331.00
IUUC-Loc-052070	Lepisosteus oculatus	37.24	2.00e-92	333.00
IUUC-Lma-053078	Leptosphaeria maculans	39.06	1.00e-08	54.30
IUUC-Laf-054426	Loxodonta africana	37.33	3.00e-95	342.00
IUUC-Mcc-055858	Macaca mulatta	37.33	4.00e-95	341.00
IUUC-Meu-056416	Macropus eugenii	27.97	2.00e-28	120.00
IUUC-Mga-059808	Meleagris gallopavo	37.71	7.00e-97	347.00
IUUC-Mmr-060987	Microcebus murinus	37.65	9.00e-95	340.00
IUUC-Mdo-061955	Monodelphis domestica	36.11	3.00e-89	323.00
IUUC-Mmu-064245	Mus musculus	37.50	4.00e-96	344.00
IUUC-Mpu-066304	Mustela putorius furo	37.12	7.00e-96	344.00
IUUC-Mlu-067139	Myotis lucifugus	37.33	1.00e-95	343.00
IUUC-Nfi-068458	Neosartorya fischeri	36.36	9.00e-10	58.50
IUUC-Ncr-068739	Neurospora crassa	24.22	3.00e-08	53.10
IUUC-Nle-069075	Nomascus leucogenys	37.33	3.00e-95	342.00
IUUC-Opr-070888	Ochotona princeps	39.26	1.00e-51	197.00
IUUC-Ont-072150	Oreochromis niloticus	37.88	5.00e-93	334.00
IUUC-Oan-073054	Ornithorhynchus anatinus	36.13	2.00e-87	316.00
IUUC-Ocu-074102	Oryctolagus cuniculus	37.42	3.00e-95	342.00
IUUC-Ola-086529	Oryzias latipes	35.25	5.00e-83	301.00
IUUC-Oga-088939	Otolemur garnettii	37.06	3.00e-95	342.00
IUUC-Oar-090266	Ovis aries	37.08	7.00e-95	340.00
IUUC-Ptr-090546	Pan troglodytes	37.33	4.00e-95	341.00
IUUC-Pan-092311	Papio anubis	37.33	5.00e-95	341.00
IUUC-Psi-093422	Pelodiscus sinensis	34.80	3.00e-95	342.00
IUUC-Pno-095093	Phaeosphaeria nodorum	46.03	5.00e-10	58.90
IUUC-Pfo-096726	Poecilia formosa	36.88	2.00e-90	325.00
IUUC-Pab-097608	Pongo abelii	37.33	4.00e-95	341.00
IUUC-Pca-100718	Procavia capensis	37.10	2.00e-55	209.00
IUUC-Pva-102226	Pteropus vampyrus	32.09	1.00e-69	257.00
IUUC-Pte-104300	Pyrenophora teres	39.68	2.00e-09	57.80
IUUC-Pyt-104434	Pyrenophora triticirepentis	39.68	2.00e-09	57.40
IUUC-Rno-105727	Rattus norvegicus	37.40	1.00e-94	340.00
IUUC-Sce-106441	Saccharomyces cerevisiae	35.48	2.00e-08	53.90
IUUC-Sha-107051	Sarcophilus harrisii	36.79	2.00e-96	345.00
IUUC-Sja-107936	Schizosaccharomyces japonicus	20.44	6.00e-09	55.50
IUUC-Sar-113097	Sorex araneus	32.34	1.00e-73	270.00
IUUC-Sre-115145	Sporisorium reilianum	24.23	2.00e-12	67.00
IUUC-Ssc-115877	Sus scrofa	37.48	5.00e-95	341.00
IUUC-Tgu-117473	Taeniopygia guttata	37.37	4.00e-97	348.00
IUUC-Tru-118135	Takifugu rubripes	37.56	5.00e-88	318.00
IUUC-Tsy-119471	Tarsius syrichta	33.84	5.00e-79	288.00
IUUC-Tni-120139	Tetraodon nigroviridis	40.98	6.00e-67	248.00
IUUC-Tre-122145	Trichoderma reesei	21.28	2.00e-10	60.80
IUUC-Tme-126928	Tuber melanosporum	27.27	4.00e-12	65.90
IUUC-Tbe-127549	Tupaia belangeri	35.35	7.00e-80	291.00
IUUC-Ttr-128887	Tursiops truncatus	32.75	2.00e-74	272.00
IUUC-Uma-129338	Ustilago maydis	23.18	2.00e-13	70.90
IUUC-Vda-129742	Verticillium dahliae	43.06	6.00e-09	55.80
IUUC-Vpa-130500	Vicugna pacos	37.71	7.00e-58	218.00
IUUC-Xtr-132896	Xenopus tropicalis	37.87	9.00e-97	347.00
IUUC-Xma-133349	Xiphophorus maculatus	36.88	4.00e-90	324.00
IUUC-Yli-134560	Yarrowia lipolytica	24.40	8.00e-18	85.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence