iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009436

Ensembl Protein ID

CADANIAP00007534

UniProt Accession

Q5AY89; C8V1Y1; DDI1_EMENI

Genbank Protein ID

EAA58559.1; CBF71367.1

Protein Name

DNA damage-inducible protein 1

Genbank Nucleotide ID

AACD01000112; BN001301

Gene Name

ANIA_06741; ddi1; AN6741

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00007534	CADANIAT00007534	CADANIAP00007534

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.50e-07	28.7	399	429
ULD/UDP/UBQ/UBQ_Other	2.50e-10	39.2	11	71

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraannnleaAv 35
             +++++e GF+reea +aL+aan++l+ A+
   Q: 399  ASIAKITELGFTREEATRALEAANGDLDGAI 429
           5799************************998 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekksg 75
            v p++t+  LK  +e++++ipp +qrL+y  ++L +d ktL ++g+ +g+ + + ++ +g
   Q: 11   IVGPDMTIELLKSIVESETSIPPSSQRLVYNQQLLgDDSKTLEQVGIGEGDMLGVHVTLRG 71
           489***********************************************98888777665 PP

Organism

Aspergillus nidulans

Functional Description
(View)

Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity).

Protein Sequence
(Fasta)

MSCSSIQAHY IVGPDMTIEL LKSIVESETS IPPSSQRLVY NQQLLGDDSK TLEQVGIGEG 60
DMLGVHVTLR GGAPSVQGQA RPTGIGGTSG ASHSQQIQQR RQQQINPDPE MIRLHILGDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTGTT CCTCTATACA GGCGCATTAC AGTAAACGTG ATACGACCGG ACCAGGCGGA 60
CCTGGACCTC ATCCCCCTAG TTGTCGGCCC GGACATGACA ATCGAGCTCC TCAAAAGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR033322--DDI1
IPR019103--Peptidase_aspartic_DDI1-type
IPR021109--Peptidase_aspartic_dom
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF09668--Asp_protease
PF00627--UBA
PF00240--ubiquitin

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004190--F:aspartic-type endopeptidase activity
GO:0015031--P:protein transport

KEGG

ani:AN6741.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000989	Aegilops tauschii	38.23	2.00e-67	248.00
IUUC-Aml-001440	Ailuropoda melanoleuca	41.79	3.00e-63	234.00
IUUC-Atr-002722	Amborella trichopoda	38.10	2.00e-64	237.00
IUUC-Apl-003902	Anas platyrhynchos	42.81	1.00e-51	194.00
IUUC-Aca-004811	Anolis carolinensis	50.43	1.00e-57	214.00
IUUC-Aly-006104	Arabidopsis lyrata	54.84	1.00e-17	81.30
IUUC-Ath-007673	Arabidopsis thaliana	37.32	1.00e-71	261.00
IUUC-Ago-007981	Ashbya gossypii	39.16	4.00e-55	207.00
IUUC-Acl-008073	Aspergillus clavatus	77.51	3.00e-164	569.00
IUUC-Afl-008728	Aspergillus flavus	77.96	3.00e-176	609.00
IUUC-Afu-008934	Aspergillus fumigatus	77.27	3.00e-165	572.00
IUUC-Ang-009596	Aspergillus niger	82.32	3.00e-127	446.00
IUUC-Aor-009968	Aspergillus oryzae	78.20	2.00e-176	609.00
IUUC-Ate-010376	Aspergillus terreus	75.59	3.00e-161	559.00
IUUC-Ame-011570	Astyanax mexicanus	41.81	3.00e-64	236.00
IUUC-Bgr-012020	Blumeria graminis	48.25	6.00e-101	359.00
IUUC-Bta-012334	Bos taurus	42.07	1.00e-63	234.00
IUUC-Bci-013907	Botrytis cinerea	50.84	2.00e-102	364.00
IUUC-Bdi-014595	Brachypodium distachyon	38.28	6.00e-71	259.00
IUUC-Bol-015258	Brassica oleracea	37.32	1.00e-68	251.00
IUUC-Bra-016740	Brassica rapa	37.56	1.00e-68	251.00
IUUC-Cel-018415	Caenorhabditis elegans	39.29	1.00e-30	125.00
IUUC-Cja-018968	Callithrix jacchus	40.45	2.00e-61	228.00
IUUC-Cfa-020530	Canis familiaris	41.50	2.00e-62	231.00
IUUC-Cpo-022103	Cavia porcellus	51.32	2.00e-49	187.00
IUUC-Cre-022841	Chlamydomonas reinhardtii	38.07	1.00e-50	192.00
IUUC-Csa-023591	Chlorocebus sabaeus	41.21	3.00e-62	231.00
IUUC-Cho-024777	Choloepus hoffmanni	32.02	5.00e-35	140.00
IUUC-Cin-025396	Ciona intestinalis	36.95	6.00e-28	115.00
IUUC-Csv-026270	Ciona savignyi	36.90	2.00e-65	241.00
IUUC-Cgl-026570	Colletotrichum gloeosporioides	52.56	7.00e-87	312.00
IUUC-Cne-026974	Cryptococcus neoformans	40.55	2.00e-80	291.00
IUUC-Cme-027324	Cyanidioschyzon merolae	44.24	5.00e-36	143.00
IUUC-Dre-028030	Danio rerio	40.51	8.00e-62	229.00
IUUC-Dno-029264	Dasypus novemcinctus	41.38	7.00e-63	232.00
IUUC-Dor-030621	Dipodomys ordii	46.03	2.00e-11	61.60
IUUC-Dse-031180	Dothistroma septosporum	35.29	3.00e-25	107.00
IUUC-Dme-032067	Drosophila melanogaster	32.23	3.00e-57	214.00
IUUC-Ete-032664	Echinops telfairi	40.79	1.00e-48	184.00
IUUC-Eca-034133	Equus caballus	38.63	4.00e-44	170.00
IUUC-Eeu-035148	Erinaceus europaeus	44.02	2.00e-49	187.00
IUUC-Fca-035376	Felis catus	41.79	2.00e-62	231.00
IUUC-Fal-037210	Ficedula albicollis	25.00	2.00e-07	48.10
IUUC-Fox-037786	Fusarium oxysporum	46.53	2.00e-95	340.00
IUUC-Gmo-039324	Gadus morhua	41.57	3.00e-61	227.00
IUUC-Ggr-039750	Gaeumannomyces graminis	48.69	3.00e-92	330.00
IUUC-Gga-040917	Gallus gallus	56.07	7.00e-30	121.00
IUUC-Gac-041785	Gasterosteus aculeatus	52.61	3.00e-63	233.00
IUUC-Gma-043134	Glycine max	36.15	1.00e-64	238.00
IUUC-Ggo-044472	Gorilla gorilla	41.03	4.00e-47	180.00
IUUC-Hsa-046783	Homo sapiens	41.50	9.00e-63	232.00
IUUC-Hvu-047222	Hordeum vulgare	41.49	6.00e-66	242.00
IUUC-Itr-048836	Ictidomys tridecemlineatus	43.30	1.00e-58	218.00
IUUC-Kpa-049208	Komagataella pastoris	35.39	5.00e-58	216.00
IUUC-Lch-049953	Latimeria chalumnae	40.68	3.00e-58	218.00
IUUC-Lpe-050925	Leersia perrieri	35.21	2.00e-61	228.00
IUUC-Loc-052009	Lepisosteus oculatus	37.50	5.00e-63	233.00
IUUC-Lma-053305	Leptosphaeria maculans	55.91	5.00e-78	283.00
IUUC-Laf-054229	Loxodonta africana	41.21	6.00e-62	229.00
IUUC-Mcc-054796	Macaca mulatta	41.50	1.00e-62	233.00
IUUC-Meu-055944	Macropus eugenii	34.97	6.00e-44	169.00
IUUC-Mpo-057402	Magnaporthe poae	48.61	8.00e-95	338.00
IUUC-Mla-058983	Melampsora laricipopulina	36.49	8.00e-22	95.10
IUUC-Mga-059910	Meleagris gallopavo	41.95	8.00e-57	212.00
IUUC-Mvi-060225	Microbotryum violaceum	52.72	3.00e-72	263.00
IUUC-Mmr-061679	Microcebus murinus	42.39	3.00e-54	203.00
IUUC-Mdo-062992	Monodelphis domestica	41.33	4.00e-63	233.00
IUUC-Mmu-063187	Mus musculus	41.21	2.00e-62	230.00
IUUC-Mac-064640	Musa acuminata	36.62	5.00e-67	246.00
IUUC-Mpu-066770	Mustela putorius furo	43.38	2.00e-53	201.00
IUUC-Mlu-067295	Myotis lucifugus	42.12	6.00e-43	166.00
IUUC-Nfi-068555	Neosartorya fischeri	77.03	2.00e-165	573.00
IUUC-Ncr-068839	Neurospora crassa	53.98	2.00e-98	351.00
IUUC-Nle-069089	Nomascus leucogenys	41.50	1.00e-62	233.00
IUUC-Opr-070199	Ochotona princeps	40.29	6.00e-55	206.00
IUUC-Ont-072300	Oreochromis niloticus	40.85	2.00e-65	241.00
IUUC-Oan-073421	Ornithorhynchus anatinus	43.73	8.00e-58	215.00
IUUC-Ocu-074510	Oryctolagus cuniculus	40.79	1.00e-53	201.00
IUUC-Oba-075183	Oryza barthii	39.21	6.00e-72	262.00
IUUC-Obr-076044	Oryza brachyantha	37.84	1.00e-66	245.00
IUUC-Ogl-077284	Oryza glaberrima	37.53	3.00e-68	250.00
IUUC-Ogu-078171	Oryza glumaepatula	37.53	4.00e-68	249.00
IUUC-Oin-079871	Oryza indica	37.53	5.00e-68	249.00
IUUC-Olo-080579	Oryza longistaminata	37.30	4.00e-68	250.00
IUUC-Ome-081972	Oryza meridionalis	37.30	1.00e-68	251.00
IUUC-Oni-083027	Oryza nivara	37.53	3.00e-68	250.00
IUUC-Opu-083491	Oryza punctata	37.30	6.00e-68	249.00
IUUC-Oru-084589	Oryza rufipogon	37.53	3.00e-68	250.00
IUUC-Osa-085703	Oryza sativa	37.53	3.00e-68	250.00
IUUC-Ola-086911	Oryzias latipes	34.52	9.00e-28	115.00
IUUC-Olu-087654	Ostreococcus lucimarinus	35.71	9.00e-56	209.00
IUUC-Oga-089146	Otolemur garnettii	41.86	7.00e-47	179.00
IUUC-Oar-089924	Ovis aries	41.41	1.00e-63	234.00
IUUC-Ptr-090938	Pan troglodytes	41.50	8.00e-63	232.00
IUUC-Pan-091767	Papio anubis	40.85	1.00e-62	231.00
IUUC-Psi-093426	Pelodiscus sinensis	38.92	4.00e-60	223.00
IUUC-Pno-094977	Phaeosphaeria nodorum	43.12	8.00e-90	322.00
IUUC-Ppa-095744	Physcomitrella patens	36.15	2.00e-59	221.00
IUUC-Pfo-097404	Poecilia formosa	39.12	4.00e-57	213.00
IUUC-Pab-098128	Pongo abelii	41.50	9.00e-63	232.00
IUUC-Pop-099792	Populus trichocarpa	36.43	7.00e-63	232.00
IUUC-Pca-100554	Procavia capensis	40.00	3.00e-45	173.00
IUUC-Ppe-101690	Prunus persica	35.71	1.00e-65	241.00
IUUC-Pva-102638	Pteropus vampyrus	32.85	5.00e-38	149.00
IUUC-Pgr-103310	Puccinia graminis	67.39	3.00e-13	66.20
IUUC-Ptt-103798	Puccinia triticina	56.64	5.00e-71	259.00
IUUC-Pte-104408	Pyrenophora teres	48.15	2.00e-84	304.00
IUUC-Pyt-104420	Pyrenophora triticirepentis	43.58	4.00e-85	306.00
IUUC-Rno-105333	Rattus norvegicus	41.21	1.00e-60	226.00
IUUC-Sce-106167	Saccharomyces cerevisiae	32.49	5.00e-55	206.00
IUUC-Sha-107599	Sarcophilus harrisii	42.55	4.00e-59	219.00
IUUC-Sja-107968	Schizosaccharomyces japonicus	46.19	2.00e-57	214.00
IUUC-Spo-108130	Schizosaccharomyces pombe	43.52	1.00e-74	271.00
IUUC-Ssl-108671	Sclerotinia sclerotiorum	50.70	1.00e-104	371.00
IUUC-Sit-109819	Setaria italica	37.18	4.00e-70	256.00
IUUC-Sly-110983	Solanum lycopersicum	36.66	2.00e-63	234.00
IUUC-Stu-112218	Solanum tuberosum	35.33	2.00e-65	241.00
IUUC-Sar-113702	Sorex araneus	23.77	1.00e-05	41.20
IUUC-Sbi-114118	Sorghum bicolor	38.08	5.00e-68	249.00
IUUC-Sre-115084	Sporisorium reilianum	44.24	7.00e-63	233.00
IUUC-Ssc-115545	Sus scrofa	41.79	1.00e-63	234.00
IUUC-Tgu-117353	Taeniopygia guttata	40.28	6.00e-58	216.00
IUUC-Tru-117838	Takifugu rubripes	39.94	4.00e-64	236.00
IUUC-Tsy-118783	Tarsius syrichta	52.12	5.00e-40	156.00
IUUC-Tni-120287	Tetraodon nigroviridis	39.13	4.00e-65	239.00
IUUC-Tca-121513	Theobroma cacao	36.81	3.00e-61	226.00
IUUC-Tvi-122402	Trichoderma virens	45.08	6.00e-30	122.00
IUUC-Tae-125534	Triticum aestivum	37.01	1.00e-68	251.00
IUUC-Tur-126159	Triticum urartu	36.38	2.00e-61	227.00
IUUC-Tme-127088	Tuber melanosporum	48.81	4.00e-105	373.00
IUUC-Tbe-127948	Tupaia belangeri	40.11	2.00e-51	194.00
IUUC-Ttr-128560	Tursiops truncatus	41.79	2.00e-63	234.00
IUUC-Uma-129478	Ustilago maydis	52.32	7.00e-59	219.00
IUUC-Vda-129758	Verticillium dahliae	47.99	3.00e-81	293.00
IUUC-Vpa-130132	Vicugna pacos	57.72	2.00e-46	178.00
IUUC-Vvi-131006	Vitis vinifera	34.51	2.00e-60	224.00
IUUC-Xtr-132758	Xenopus tropicalis	50.00	1.00e-56	211.00
IUUC-Xma-133125	Xiphophorus maculatus	39.84	6.00e-56	209.00
IUUC-Yli-134530	Yarrowia lipolytica	34.43	2.00e-58	217.00
IUUC-Zma-135856	Zea mays	36.95	2.00e-67	248.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence