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Tag Content
UUCD2 ID IUUC-Mcc-055075
UUCD1 version UUC-MaM-00393
Ensembl Protein ID ENSMMUP00000024720.2
UniProt Accession F6ZQL6; F6ZQL6_MACMU
Genbank Protein ID AFE80478.1; AFE80479.1; AFE80480.1; AFE80481.1; AFE80482.1; AFE80483.1; AFE80484.1; AFE80485.1; AFE80486.1
Protein Name E3 ubiquitin-protein ligase synoviolin isoform b
Genbank Nucleotide ID JSUE03012064; JU336726; JU336727; JU336728; JU336729; JU336730; JU336731; JU336732; JU336733
Gene Name SYVN1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000018781.3 ENSMMUT00000026406.3 ENSMMUP00000024720.2
ENSMMUG00000018781.3 ENSMMUT00000026404.3 ENSMMUP00000024718.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 4.70e-09 37.7 291 330
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e++ +g + lpC+H+fh++Cl  w       +++++CP+Cr
   Q: 291  CIICREEMVTGAKRLPCNHIFHTSCLRSW------FQRQQTCPTCR 330
           ********99999****************......**********8 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MFRTAVMMAA SLALTGAVVA HAYYLKHQFY PTVVYLTKSS PSMAVLYIQA FVLVFLLGKV 60
MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS PRFVALFTLL LFLKCFHWLA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055075|E3,RING|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GACCCCCGAA GTTCCGGTTC GCAGGGGGTG GGGAGTGTTG TTAACCGGAG CGGCCGCCGC 60
AGTCGCGCGG ATTGAGCGGG CTCGCGGCGT TGCGTTCCTG GTGAGTGGGG CGAAGTCTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055075|E3,RING|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR032832--E3_lig_synoviolin/Hrd1
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0044322--C:endoplasmic reticulum quality control compartment
GO:0000836--C:Hrd1p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0016021--C:integral component of membrane
GO:0005654--C:nucleoplasm
GO:0005790--C:smooth endoplasmic reticulum
GO:0016874--F:ligase activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0051082--F:unfolded protein binding
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:1902236--P:negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0000209--P:protein polyubiquitination
GO:0050821--P:protein stabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG mcc:716698
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000344 Aegilops tauschii 37.28 4.00e-52 198.00
IUUC-Aml-001539 Ailuropoda melanoleuca 99.70 0.00e+00 707.00
IUUC-Atr-002892 Amborella trichopoda 44.48 9.00e-78 284.00
IUUC-Apl-004003 Anas platyrhynchos 95.76 1.00e-65 241.00
IUUC-Aca-004799 Anolis carolinensis 97.81 0.00e+00 662.00
IUUC-Aly-006352 Arabidopsis lyrata 44.41 3.00e-75 275.00
IUUC-Ath-006773 Arabidopsis thaliana 44.41 6.00e-75 275.00
IUUC-Ago-007894 Ashbya gossypii 25.16 2.00e-18 87.40
IUUC-Acl-008041 Aspergillus clavatus 30.53 1.00e-55 211.00
IUUC-Afl-008427 Aspergillus flavus 31.28 1.00e-50 194.00
IUUC-Afu-009023 Aspergillus fumigatus 31.11 2.00e-56 214.00
IUUC-Ani-009133 Aspergillus nidulans 31.50 1.00e-58 221.00
IUUC-Ang-009612 Aspergillus niger 34.49 7.00e-56 212.00
IUUC-Aor-010045 Aspergillus oryzae 30.94 7.00e-57 215.00
IUUC-Ate-010533 Aspergillus terreus 31.83 1.00e-56 214.00
IUUC-Ame-011083 Astyanax mexicanus 93.38 0.00e+00 631.00
IUUC-Bgr-012122 Blumeria graminis 28.54 2.00e-48 187.00
IUUC-Bta-013375 Bos taurus 100.00 0.00e+00 704.00
IUUC-Bci-013675 Botrytis cinerea 37.25 2.00e-23 104.00
IUUC-Bdi-015070 Brachypodium distachyon 42.69 6.00e-69 254.00
IUUC-Bol-015674 Brassica oleracea 43.50 6.00e-75 275.00
IUUC-Bra-017516 Brassica rapa 43.20 5.00e-73 268.00
IUUC-Cel-018422 Caenorhabditis elegans 57.70 1.00e-117 417.00
IUUC-Cja-019779 Callithrix jacchus 97.35 0.00e+00 672.00
IUUC-Cfa-020189 Canis familiaris 100.00 0.00e+00 704.00
IUUC-Cpo-022209 Cavia porcellus 99.70 0.00e+00 704.00
IUUC-Cre-022743 Chlamydomonas reinhardtii 39.24 2.00e-64 239.00
IUUC-Csa-023571 Chlorocebus sabaeus 100.00 0.00e+00 702.00
IUUC-Cho-024889 Choloepus hoffmanni 88.43 4.00e-178 618.00
IUUC-Csv-026160 Ciona savignyi 60.23 3.00e-122 431.00
IUUC-Cne-027002 Cryptococcus neoformans 40.90 3.00e-76 280.00
IUUC-Cme-027285 Cyanidioschyzon merolae 35.77 1.00e-50 194.00
IUUC-Dre-027999 Danio rerio 93.06 0.00e+00 637.00
IUUC-Dno-029250 Dasypus novemcinctus 99.70 0.00e+00 707.00
IUUC-Dor-030718 Dipodomys ordii 95.27 0.00e+00 670.00
IUUC-Dse-031498 Dothistroma septosporum 34.76 2.00e-27 117.00
IUUC-Dme-031969 Drosophila melanogaster 66.06 4.00e-143 501.00
IUUC-Ete-032592 Echinops telfairi 98.46 7.00e-32 130.00
IUUC-Eca-033258 Equus caballus 100.00 0.00e+00 707.00
IUUC-Fca-035980 Felis catus 99.70 0.00e+00 703.00
IUUC-Fal-037554 Ficedula albicollis 68.86 1.00e-99 356.00
IUUC-Fox-037902 Fusarium oxysporum 31.22 3.00e-52 200.00
IUUC-Fso-038418 Fusarium solani 30.71 2.00e-48 187.00
IUUC-Gmo-039288 Gadus morhua 90.55 0.00e+00 628.00
IUUC-Ggr-040076 Gaeumannomyces graminis 31.68 7.00e-51 195.00
IUUC-Gga-040347 Gallus gallus 92.31 2.00e-75 273.00
IUUC-Gac-042347 Gasterosteus aculeatus 92.43 0.00e+00 628.00
IUUC-Gma-044123 Glycine max 44.02 1.00e-74 273.00
IUUC-Ggo-044858 Gorilla gorilla 100.00 0.00e+00 706.00
IUUC-Hsa-046412 Homo sapiens 100.00 0.00e+00 707.00
IUUC-Hvu-047279 Hordeum vulgare 42.99 1.00e-69 256.00
IUUC-Itr-048924 Ictidomys tridecemlineatus 100.00 0.00e+00 702.00
IUUC-Kpa-049117 Komagataella pastoris 29.19 6.00e-31 128.00
IUUC-Lch-049533 Latimeria chalumnae 49.14 3.00e-73 269.00
IUUC-Lpe-051229 Leersia perrieri 32.38 2.00e-34 139.00
IUUC-Loc-052843 Lepisosteus oculatus 93.06 1.00e-121 429.00
IUUC-Lma-052997 Leptosphaeria maculans 33.07 2.00e-60 227.00
IUUC-Laf-053482 Loxodonta africana 100.00 0.00e+00 701.00
IUUC-Meu-056683 Macropus eugenii 97.72 3.00e-151 528.00
IUUC-Mor-057082 Magnaporthe oryzae 31.34 5.00e-55 209.00
IUUC-Mpo-057573 Magnaporthe poae 30.98 2.00e-50 194.00
IUUC-Mtr-058601 Medicago truncatula 44.71 1.00e-79 290.00
IUUC-Mla-059168 Melampsora laricipopulina 40.95 8.00e-79 288.00
IUUC-Mga-059510 Meleagris gallopavo 98.80 5.00e-47 180.00
IUUC-Mvi-060515 Microbotryum violaceum 39.57 4.00e-66 246.00
IUUC-Mmr-060922 Microcebus murinus 100.00 0.00e+00 704.00
IUUC-Mdo-062491 Monodelphis domestica 98.52 0.00e+00 679.00
IUUC-Mmu-063770 Mus musculus 100.00 0.00e+00 703.00
IUUC-Mac-064789 Musa acuminata 43.50 7.00e-79 288.00
IUUC-Mpu-066107 Mustela putorius furo 99.41 0.00e+00 709.00
IUUC-Mlu-067918 Myotis lucifugus 97.75 0.00e+00 639.00
IUUC-Nfi-068389 Neosartorya fischeri 30.85 7.00e-56 212.00
IUUC-Ncr-068742 Neurospora crassa 32.42 5.00e-49 189.00
IUUC-Nle-069139 Nomascus leucogenys 100.00 0.00e+00 707.00
IUUC-Opr-070898 Ochotona princeps 99.52 2.00e-125 442.00
IUUC-Ont-071991 Oreochromis niloticus 91.08 0.00e+00 642.00
IUUC-Ocu-074065 Oryctolagus cuniculus 99.11 0.00e+00 699.00
IUUC-Oba-075221 Oryza barthii 41.49 9.00e-68 251.00
IUUC-Obr-076914 Oryza brachyantha 42.90 4.00e-64 238.00
IUUC-Ogu-078124 Oryza glumaepatula 41.49 9.00e-68 251.00
IUUC-Oin-080013 Oryza indica 39.82 3.00e-64 239.00
IUUC-Olo-080247 Oryza longistaminata 39.88 1.00e-60 226.00
IUUC-Ome-081769 Oryza meridionalis 42.09 2.00e-70 259.00
IUUC-Oni-082946 Oryza nivara 41.49 9.00e-68 251.00
IUUC-Opu-083268 Oryza punctata 36.13 6.00e-51 195.00
IUUC-Oru-085114 Oryza rufipogon 41.49 9.00e-68 251.00
IUUC-Osa-085829 Oryza sativa 42.09 2.00e-70 259.00
IUUC-Ola-087449 Oryzias latipes 92.70 0.00e+00 629.00
IUUC-Olu-087894 Ostreococcus lucimarinus 42.04 1.00e-73 270.00
IUUC-Oga-089036 Otolemur garnettii 100.00 0.00e+00 702.00
IUUC-Oar-089715 Ovis aries 100.00 0.00e+00 707.00
IUUC-Ptr-091000 Pan troglodytes 100.00 0.00e+00 701.00
IUUC-Pan-092187 Papio anubis 100.00 0.00e+00 707.00
IUUC-Psi-093377 Pelodiscus sinensis 97.04 0.00e+00 628.00
IUUC-Pma-094759 Petromyzon marinus 92.25 1.00e-79 290.00
IUUC-Pno-094883 Phaeosphaeria nodorum 32.62 9.00e-58 218.00
IUUC-Ppa-095684 Physcomitrella patens 44.51 3.00e-71 262.00
IUUC-Pfo-096861 Poecilia formosa 90.21 0.00e+00 635.00
IUUC-Pab-098030 Pongo abelii 100.00 0.00e+00 707.00
IUUC-Pop-099245 Populus trichocarpa 44.14 4.00e-80 292.00
IUUC-Pca-100191 Procavia capensis 96.49 0.00e+00 680.00
IUUC-Ppe-101829 Prunus persica 43.50 2.00e-79 290.00
IUUC-Pva-102689 Pteropus vampyrus 99.70 0.00e+00 708.00
IUUC-Pgr-103286 Puccinia graminis 37.82 2.00e-73 270.00
IUUC-Ptt-103919 Puccinia triticina 38.27 5.00e-72 265.00
IUUC-Pte-104372 Pyrenophora teres 33.50 1.00e-63 238.00
IUUC-Pyt-104456 Pyrenophora triticirepentis 33.25 1.00e-61 231.00
IUUC-Rno-105723 Rattus norvegicus 100.00 0.00e+00 701.00
IUUC-Sce-106348 Saccharomyces cerevisiae 26.25 2.00e-24 107.00
IUUC-Sha-107300 Sarcophilus harrisii 97.01 4.00e-154 538.00
IUUC-Sja-107685 Schizosaccharomyces japonicus 27.79 5.00e-39 155.00
IUUC-Spo-108308 Schizosaccharomyces pombe 29.77 7.00e-39 155.00
IUUC-Ssl-108558 Sclerotinia sclerotiorum 37.25 1.00e-23 105.00
IUUC-Smo-109123 Selaginella moellendorffii 46.69 5.00e-76 278.00
IUUC-Sit-110276 Setaria italica 43.28 7.00e-71 261.00
IUUC-Sly-111819 Solanum lycopersicum 44.82 3.00e-72 265.00
IUUC-Stu-112048 Solanum tuberosum 44.76 1.00e-75 277.00
IUUC-Sbi-114027 Sorghum bicolor 42.39 9.00e-78 284.00
IUUC-Sre-115212 Sporisorium reilianum 36.76 3.00e-63 236.00
IUUC-Ssc-116323 Sus scrofa 99.70 0.00e+00 699.00
IUUC-Tgu-117156 Taeniopygia guttata 94.81 1.00e-39 153.00
IUUC-Tru-118045 Takifugu rubripes 89.85 0.00e+00 636.00
IUUC-Tsy-118823 Tarsius syrichta 86.52 3.00e-160 557.00
IUUC-Tni-120106 Tetraodon nigroviridis 90.51 6.00e-130 457.00
IUUC-Tca-121462 Theobroma cacao 45.51 2.00e-79 289.00
IUUC-Tre-122204 Trichoderma reesei 38.73 9.00e-27 115.00
IUUC-Tvi-122550 Trichoderma virens 30.77 2.00e-50 194.00
IUUC-Tae-125239 Triticum aestivum 43.28 5.00e-72 265.00
IUUC-Tur-126538 Triticum urartu 38.54 3.00e-50 193.00
IUUC-Tme-127197 Tuber melanosporum 40.73 1.00e-67 251.00
IUUC-Tbe-127385 Tupaia belangeri 90.39 0.00e+00 635.00
IUUC-Ttr-128795 Tursiops truncatus 100.00 0.00e+00 706.00
IUUC-Uma-129401 Ustilago maydis 35.31 2.00e-52 201.00
IUUC-Vda-129968 Verticillium dahliae 29.35 8.00e-42 165.00
IUUC-Vvi-130944 Vitis vinifera 46.22 2.00e-79 289.00
IUUC-Xtr-131884 Xenopus tropicalis 94.05 0.00e+00 653.00
IUUC-Xma-133488 Xiphophorus maculatus 90.50 0.00e+00 640.00
IUUC-Yli-134552 Yarrowia lipolytica 25.35 2.00e-35 143.00
IUUC-Zma-135530 Zea mays 43.45 4.00e-67 249.00
Created Date 25-Jun-2017

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