iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048996

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01119513

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000024501.1	ENSSTOT00000028012.1	ENSSTOP00000021965.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.30e-17	62.1	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE DTDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINSED 60
EKGGKSRSKS ESLMGTLKRR LSVKQKPKGK GSTPPGGLAE EDTFSSSSAP VVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TTAGTCTTAA AACCTTCCGG AAGTCTTTTA ATTTGAATAA AAGTAAAGAA 60
GACACTGATT TCATGGTAGT ACAACAGCCA TCCCTAGCCA GTGACTTTGG AAAAGATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	94.95	0.00e+00	947.00
IUUC-Atr-002940	Amborella trichopoda	28.18	6.80e-02	31.20
IUUC-Apl-004035	Anas platyrhynchos	88.60	0.00e+00	885.00
IUUC-Aca-004782	Anolis carolinensis	85.82	0.00e+00	846.00
IUUC-Afl-008492	Aspergillus flavus	25.62	1.40e-01	30.80
IUUC-Ame-011790	Astyanax mexicanus	70.58	0.00e+00	644.00
IUUC-Bta-012579	Bos taurus	95.22	5.00e-109	387.00
IUUC-Bol-015843	Brassica oleracea	28.77	2.90e-02	32.70
IUUC-Cel-018643	Caenorhabditis elegans	33.59	9.00e-12	62.80
IUUC-Cja-019528	Callithrix jacchus	93.83	0.00e+00	979.00
IUUC-Cfa-020678	Canis familiaris	94.58	0.00e+00	968.00
IUUC-Cpo-021947	Cavia porcellus	95.33	0.00e+00	1004.00
IUUC-Csa-023935	Chlorocebus sabaeus	93.83	0.00e+00	958.00
IUUC-Cho-024477	Choloepus hoffmanni	90.84	0.00e+00	954.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	6.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	25.00	3.40e-01	30.00
IUUC-Dre-027636	Danio rerio	69.78	0.00e+00	642.00
IUUC-Dno-029048	Dasypus novemcinctus	91.78	0.00e+00	942.00
IUUC-Dor-030401	Dipodomys ordii	92.16	0.00e+00	919.00
IUUC-Dme-031876	Drosophila melanogaster	46.34	1.00e-37	152.00
IUUC-Ete-033116	Echinops telfairi	50.53	8.00e-61	226.00
IUUC-Eca-033825	Equus caballus	94.58	0.00e+00	927.00
IUUC-Fca-036253	Felis catus	93.08	0.00e+00	870.00
IUUC-Fal-037614	Ficedula albicollis	88.97	0.00e+00	888.00
IUUC-Fox-037898	Fusarium oxysporum	28.57	1.70e-02	32.70
IUUC-Gmo-038928	Gadus morhua	68.63	0.00e+00	660.00
IUUC-Gga-040177	Gallus gallus	88.04	0.00e+00	879.00
IUUC-Gac-042263	Gasterosteus aculeatus	70.11	0.00e+00	698.00
IUUC-Ggo-045288	Gorilla gorilla	93.27	0.00e+00	958.00
IUUC-Hsa-046409	Homo sapiens	93.64	0.00e+00	959.00
IUUC-Lch-050354	Latimeria chalumnae	83.58	0.00e+00	868.00
IUUC-Loc-052319	Lepisosteus oculatus	80.60	0.00e+00	816.00
IUUC-Laf-054070	Loxodonta africana	90.65	0.00e+00	902.00
IUUC-Mcc-055045	Macaca mulatta	93.46	0.00e+00	955.00
IUUC-Meu-055917	Macropus eugenii	88.79	0.00e+00	942.00
IUUC-Mga-059273	Meleagris gallopavo	88.41	0.00e+00	879.00
IUUC-Mmr-061597	Microcebus murinus	93.83	0.00e+00	962.00
IUUC-Mdo-062492	Monodelphis domestica	64.14	1.00e-110	392.00
IUUC-Mmu-063374	Mus musculus	83.46	0.00e+00	828.00
IUUC-Mpu-065967	Mustela putorius furo	90.47	0.00e+00	909.00
IUUC-Mlu-067532	Myotis lucifugus	92.34	0.00e+00	922.00
IUUC-Nle-069373	Nomascus leucogenys	93.83	0.00e+00	959.00
IUUC-Opr-070873	Ochotona princeps	91.40	0.00e+00	957.00
IUUC-Ont-072498	Oreochromis niloticus	71.82	0.00e+00	724.00
IUUC-Oan-072943	Ornithorhynchus anatinus	70.85	1.00e-96	345.00
IUUC-Ocu-073870	Oryctolagus cuniculus	94.02	0.00e+00	955.00
IUUC-Ola-086866	Oryzias latipes	90.23	5.00e-105	373.00
IUUC-Oga-089057	Otolemur garnettii	91.40	0.00e+00	910.00
IUUC-Oar-089841	Ovis aries	61.57	1.00e-165	575.00
IUUC-Ptr-091054	Pan troglodytes	93.64	0.00e+00	957.00
IUUC-Pma-094253	Petromyzon marinus	43.08	1.00e-96	347.00
IUUC-Pfo-097179	Poecilia formosa	64.64	2.00e-174	605.00
IUUC-Pab-097702	Pongo abelii	93.83	0.00e+00	959.00
IUUC-Pca-100671	Procavia capensis	85.27	2.00e-129	456.00
IUUC-Rno-106044	Rattus norvegicus	81.34	0.00e+00	823.00
IUUC-Sha-107139	Sarcophilus harrisii	88.35	0.00e+00	867.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.20e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	43.59	1.30e-01	30.80
IUUC-Ssc-115343	Sus scrofa	91.96	0.00e+00	941.00
IUUC-Tgu-117061	Taeniopygia guttata	88.41	0.00e+00	884.00
IUUC-Tni-119829	Tetraodon nigroviridis	68.08	0.00e+00	641.00
IUUC-Tae-123723	Triticum aestivum	27.50	3.90e-02	33.50
IUUC-Ttr-129148	Tursiops truncatus	91.96	0.00e+00	890.00
IUUC-Vpa-130780	Vicugna pacos	89.35	0.00e+00	858.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.10e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	81.50	0.00e+00	842.00
IUUC-Xma-133904	Xiphophorus maculatus	68.51	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence