iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027479

Ensembl Protein ID

ENSDARP00000092078.3

UniProt Accession

F1Q9E0; F1Q9E0_DANRE

Genbank Protein ID

ENSDARP00000092078

Protein Name

Ubiquitin-like protein ATG12

Genbank Nucleotide ID

CU459065

Gene Name

atg12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000069545.4	ENSDART00000101304.4	ENSDARP00000092078.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UBL/ATG12	72.32	1.00e-43	172.00	IUUC-Hsa-046903

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Functional Description
(View)

Ubiquitin-like protein involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

MSDNAESPTE NPKDEHSLQH AVTDHSESSD EKKKIDVLLK AVGDTPIMKT KKWSVERRRT 60
IQSLAQFISR FLKLEPSEQL FIYVNQSFAP SPDQEVGVLF ECFGSDGKLV LHYCKSQAWG 120

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Nucleotide Sequence
(Fasta)

GAAAGTGAGC TCAGCGTGCG CCTGCTCTGT TCGTTGTGCT GCTTGTGTGT GTCAGTCTGA 60
GGATGTCTGA CAACGCAGAA TCTCCTACAG AAAACCCGAA AGATGAACAT TCGCTTCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR007242--Atg12
IPR029071--Ubiquitin-rel_dom

Pfam

PF04110--APG12

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0034045--C:pre-autophagosomal structure membrane
GO:0019776--F:Atg8 ligase activity
GO:0000045--P:autophagosome assembly
GO:0006501--P:C-terminal protein lipidation
GO:0000422--P:mitophagy
GO:0044804--P:nucleophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001177	Aegilops tauschii	37.63	3.00e-15	73.20
IUUC-Aml-002116	Ailuropoda melanoleuca	84.95	6.00e-44	169.00
IUUC-Atr-002615	Amborella trichopoda	41.05	2.00e-16	77.00
IUUC-Apl-003753	Anas platyrhynchos	92.50	2.00e-19	87.00
IUUC-Aca-005231	Anolis carolinensis	83.87	5.00e-39	153.00
IUUC-Aly-006172	Arabidopsis lyrata	40.00	6.00e-16	75.10
IUUC-Ath-006953	Arabidopsis thaliana	42.11	1.00e-16	77.80
IUUC-Ago-007970	Ashbya gossypii	50.00	6.00e-06	43.90
IUUC-Acl-008072	Aspergillus clavatus	29.36	2.00e-11	60.80
IUUC-Afl-008725	Aspergillus flavus	31.25	2.00e-12	65.50
IUUC-Afu-008967	Aspergillus fumigatus	29.36	2.00e-11	62.00
IUUC-Ani-009248	Aspergillus nidulans	28.57	4.00e-11	60.80
IUUC-Ang-009684	Aspergillus niger	27.43	1.00e-11	62.80
IUUC-Aor-009947	Aspergillus oryzae	31.25	2.00e-12	65.50
IUUC-Ame-011656	Astyanax mexicanus	79.51	1.00e-51	194.00
IUUC-Bgr-012174	Blumeria graminis	33.33	1.00e-12	65.50
IUUC-Bta-012483	Bos taurus	84.78	7.00e-44	168.00
IUUC-Bci-013755	Botrytis cinerea	29.47	2.00e-08	50.80
IUUC-Bdi-014156	Brachypodium distachyon	35.79	1.00e-14	71.20
IUUC-Bol-015683	Brassica oleracea	40.00	2.00e-16	77.00
IUUC-Bra-016802	Brassica rapa	42.05	1.00e-15	74.30
IUUC-Cel-018242	Caenorhabditis elegans	30.77	6.00e-11	59.30
IUUC-Cja-019514	Callithrix jacchus	79.41	8.00e-44	169.00
IUUC-Cfa-020748	Canis familiaris	84.95	7.00e-44	169.00
IUUC-Cpo-021965	Cavia porcellus	84.95	9.00e-44	169.00
IUUC-Cre-023009	Chlamydomonas reinhardtii	32.26	8.00e-12	61.20
IUUC-Csa-023494	Chlorocebus sabaeus	83.87	5.00e-44	169.00
IUUC-Cho-024631	Choloepus hoffmanni	84.78	2.00e-43	167.00
IUUC-Cin-025609	Ciona intestinalis	54.64	2.00e-30	123.00
IUUC-Cgl-026722	Colletotrichum gloeosporioides	34.51	1.00e-12	65.90
IUUC-Dno-029693	Dasypus novemcinctus	70.65	2.00e-32	131.00
IUUC-Dse-031440	Dothistroma septosporum	33.03	3.00e-12	64.30
IUUC-Dme-031892	Drosophila melanogaster	45.95	6.00e-29	118.00
IUUC-Ete-032550	Echinops telfairi	85.88	8.00e-41	158.00
IUUC-Eca-033553	Equus caballus	83.87	3.00e-44	170.00
IUUC-Fca-036524	Felis catus	84.95	1.00e-42	165.00
IUUC-Fal-036942	Ficedula albicollis	83.72	1.00e-41	160.00
IUUC-Fox-037753	Fusarium oxysporum	31.82	2.00e-10	58.50
IUUC-Gmo-039498	Gadus morhua	76.67	9.00e-50	188.00
IUUC-Ggr-039852	Gaeumannomyces graminis	32.58	1.00e-09	56.60
IUUC-Gga-041263	Gallus gallus	70.00	7.00e-45	172.00
IUUC-Gac-042346	Gasterosteus aculeatus	79.17	3.00e-46	176.00
IUUC-Gma-042896	Glycine max	42.11	3.00e-16	76.30
IUUC-Ggo-045601	Gorilla gorilla	83.87	1.00e-43	168.00
IUUC-Hsa-046903	Homo sapiens	83.87	3.00e-44	170.00
IUUC-Hvu-047239	Hordeum vulgare	38.71	3.00e-15	73.20
IUUC-Itr-048445	Ictidomys tridecemlineatus	84.95	5.00e-44	169.00
IUUC-Kpa-049355	Komagataella pastoris	26.95	3.00e-07	47.80
IUUC-Lch-050619	Latimeria chalumnae	83.15	3.00e-43	167.00
IUUC-Loc-052102	Lepisosteus oculatus	83.64	7.00e-24	101.00
IUUC-Lma-053299	Leptosphaeria maculans	27.94	4.00e-06	43.50
IUUC-Laf-054205	Loxodonta africana	80.39	1.00e-44	172.00
IUUC-Meu-056804	Macropus eugenii	85.87	4.00e-44	170.00
IUUC-Mor-057052	Magnaporthe oryzae	31.11	2.00e-09	55.10
IUUC-Mtr-057961	Medicago truncatula	41.05	2.00e-16	76.60
IUUC-Mla-059045	Melampsora laricipopulina	40.23	1.00e-18	84.70
IUUC-Mvi-060360	Microbotryum violaceum	39.08	8.00e-18	82.40
IUUC-Mmr-061654	Microcebus murinus	70.80	2.00e-44	170.00
IUUC-Mdo-062649	Monodelphis domestica	70.73	3.00e-45	173.00
IUUC-Mmu-064105	Mus musculus	84.78	7.00e-44	169.00
IUUC-Mac-065532	Musa acuminata	38.95	1.00e-16	77.80
IUUC-Mpu-066269	Mustela putorius furo	69.67	8.00e-45	172.00
IUUC-Mlu-067631	Myotis lucifugus	72.32	4.00e-44	170.00
IUUC-Nfi-068468	Neosartorya fischeri	29.36	9.00e-12	62.00
IUUC-Ncr-068750	Neurospora crassa	27.47	9.00e-10	56.20
IUUC-Nle-069483	Nomascus leucogenys	83.87	8.00e-44	169.00
IUUC-Opr-070936	Ochotona princeps	84.78	3.00e-43	167.00
IUUC-Obr-076322	Oryza brachyantha	32.26	4.00e-13	65.90
IUUC-Ogl-077226	Oryza glaberrima	31.71	3.00e-11	59.70
IUUC-Oin-079220	Oryza indica	46.51	1.00e-08	51.60
IUUC-Olo-080688	Oryza longistaminata	31.71	3.00e-11	59.70
IUUC-Ome-081265	Oryza meridionalis	31.71	3.00e-11	59.70
IUUC-Oru-084342	Oryza rufipogon	33.33	4.00e-12	64.70
IUUC-Osa-086212	Oryza sativa	31.71	3.00e-11	59.70
IUUC-Ola-087277	Oryzias latipes	78.45	7.00e-50	188.00
IUUC-Olu-087780	Ostreococcus lucimarinus	32.63	2.00e-11	60.10
IUUC-Oga-088175	Otolemur garnettii	83.87	3.00e-44	170.00
IUUC-Oar-089477	Ovis aries	84.78	3.00e-43	167.00
IUUC-Ptr-091129	Pan troglodytes	83.87	2.00e-43	168.00
IUUC-Psi-093351	Pelodiscus sinensis	81.63	8.00e-45	172.00
IUUC-Pno-094948	Phaeosphaeria nodorum	25.00	2.00e-04	37.70
IUUC-Ppa-095788	Physcomitrella patens	40.00	5.00e-17	79.00
IUUC-Pfo-096993	Poecilia formosa	79.17	2.00e-52	197.00
IUUC-Pab-098502	Pongo abelii	83.87	2.00e-43	168.00
IUUC-Pop-098819	Populus trichocarpa	39.36	1.00e-15	74.30
IUUC-Pca-100144	Procavia capensis	60.78	8.00e-29	119.00
IUUC-Ppe-101560	Prunus persica	41.67	2.00e-14	69.70
IUUC-Pva-102810	Pteropus vampyrus	62.50	5.00e-31	126.00
IUUC-Pgr-103531	Puccinia graminis	37.78	6.00e-19	85.50
IUUC-Ptt-103753	Puccinia triticina	39.08	9.00e-19	85.10
IUUC-Pyt-104733	Pyrenophora triticirepentis	25.66	3.00e-09	54.30
IUUC-Rno-106072	Rattus norvegicus	70.54	1.00e-43	168.00
IUUC-Sce-106275	Saccharomyces cerevisiae	31.18	2.00e-09	55.50
IUUC-Sha-107554	Sarcophilus harrisii	75.68	4.00e-45	173.00
IUUC-Sja-107682	Schizosaccharomyces japonicus	27.37	1.00e-12	65.50
IUUC-Spo-108275	Schizosaccharomyces pombe	31.73	7.00e-16	76.30
IUUC-Smo-109151	Selaginella moellendorffii	27.91	1.00e-09	54.30
IUUC-Sit-110270	Setaria italica	36.56	3.00e-15	73.20
IUUC-Sly-111862	Solanum lycopersicum	41.11	2.00e-15	73.90
IUUC-Stu-112663	Solanum tuberosum	52.38	5.00e-09	52.80
IUUC-Sbi-114148	Sorghum bicolor	36.56	3.00e-15	73.20
IUUC-Sre-115216	Sporisorium reilianum	38.89	2.00e-20	90.90
IUUC-Ssc-116051	Sus scrofa	83.87	3.00e-44	170.00
IUUC-Tgu-117008	Taeniopygia guttata	76.47	3.00e-18	82.80
IUUC-Tru-118466	Takifugu rubripes	86.05	1.00e-42	163.00
IUUC-Tsy-119334	Tarsius syrichta	61.79	1.00e-37	149.00
IUUC-Tni-119792	Tetraodon nigroviridis	86.05	1.00e-42	164.00
IUUC-Tca-121861	Theobroma cacao	39.80	8.00e-16	75.50
IUUC-Tvi-122499	Trichoderma virens	32.95	1.00e-10	58.50
IUUC-Tae-123431	Triticum aestivum	37.63	3.00e-15	73.20
IUUC-Tme-126934	Tuber melanosporum	31.03	4.00e-12	63.90
IUUC-Ttr-129001	Tursiops truncatus	79.57	3.00e-38	150.00
IUUC-Uma-129324	Ustilago maydis	38.89	4.00e-20	90.10
IUUC-Vda-129846	Verticillium dahliae	30.68	5.00e-09	53.50
IUUC-Vpa-130202	Vicugna pacos	95.00	4.00e-20	90.90
IUUC-Vvi-131474	Vitis vinifera	35.90	7.00e-09	52.80
IUUC-Xtr-132782	Xenopus tropicalis	67.80	1.00e-43	168.00
IUUC-Xma-134140	Xiphophorus maculatus	79.17	5.00e-53	199.00
IUUC-Yli-134517	Yarrowia lipolytica	32.50	2.00e-08	52.40
IUUC-Zma-134764	Zea mays	36.56	2.00e-15	73.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence