iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	14747994

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.0047	15.4	110	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 101  glldrlpeeilveilkll...dkeellraa...............rvcrrwq.elasqkalw 143
           ++++ lp+ei+++i+++l   +kee+l+ +               +vcr+w+ ++   k ++
   Q: 110  SVKMVLPWEIQHRIIHYLdipEKEEKLNKTangkktttginmnylLVCRNWYaMCLP-KLYY 170
           56899*************7664444444435999******************66665.5554 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity).

Protein Sequence
(Fasta)

MANKSRPKKI KAPYRKYVAG EGFSSTRNDN KAKEFTITIP EDAELIETPQ GSYYYDETND 60
TIVKLTRLSN EKKDKKGRKQ SPSSSSTSSS KGEKNGKVIE SEEARMHSVS VKMVLPWEIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAACA AATCACGACC CAAGAAAATC AAGGCTCCTT ACAGGAAGTA CGTGGCGGGA 60
GAGGGTTTCT CCTCTACAAG AAATGATAAT AAGGCTAAAG AATTCACTAT CACTATACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR032675--L_dom-like

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0030674--F:protein binding, bridging
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

sce:YDR306C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007902	Ashbya gossypii	57.77	2.00e-118	416.00
IUUC-Acl-008311	Aspergillus clavatus	29.47	1.00e-21	95.50
IUUC-Afl-008416	Aspergillus flavus	33.62	6.00e-21	93.20
IUUC-Afu-008917	Aspergillus fumigatus	29.53	9.00e-25	105.00
IUUC-Ani-009234	Aspergillus nidulans	37.42	2.00e-18	84.30
IUUC-Ang-009634	Aspergillus niger	35.64	1.00e-21	95.50
IUUC-Aor-010218	Aspergillus oryzae	33.62	4.00e-21	93.60
IUUC-Ame-011703	Astyanax mexicanus	47.50	3.00e-03	36.20
IUUC-Bgr-012291	Blumeria graminis	32.60	5.00e-39	152.00
IUUC-Bci-013917	Botrytis cinerea	29.19	8.00e-38	149.00
IUUC-Bdi-014492	Brachypodium distachyon	22.62	4.50e-02	30.80
IUUC-Bra-017048	Brassica rapa	37.93	4.60e-01	26.90
IUUC-Cel-018628	Caenorhabditis elegans	27.91	6.00e-03	33.10
IUUC-Cja-019888	Callithrix jacchus	36.73	5.10e-01	23.10
IUUC-Cre-022760	Chlamydomonas reinhardtii	42.11	9.00e-02	30.80
IUUC-Dse-031296	Dothistroma septosporum	31.07	1.00e-35	142.00
IUUC-Dme-031632	Drosophila melanogaster	23.43	2.40e-02	31.20
IUUC-Fox-037672	Fusarium oxysporum	28.57	7.20e-02	30.80
IUUC-Gga-040805	Gallus gallus	22.97	1.30e+00	26.20
IUUC-Kpa-049333	Komagataella pastoris	52.13	3.00e-90	323.00
IUUC-Lma-053240	Leptosphaeria maculans	29.70	4.00e-27	113.00
IUUC-Mpo-057412	Magnaporthe poae	25.96	4.90e-02	31.60
IUUC-Mla-059126	Melampsora laricipopulina	23.79	1.00e-02	32.70
IUUC-Nfi-068587	Neosartorya fischeri	28.21	7.00e-24	102.00
IUUC-Opr-071134	Ochotona princeps	30.67	6.00e-02	29.60
IUUC-Ont-071882	Oreochromis niloticus	24.71	2.00e-03	35.40
IUUC-Oba-075013	Oryza barthii	30.00	4.30e-02	29.60
IUUC-Ogl-077714	Oryza glaberrima	30.00	7.10e-02	29.30
IUUC-Ogu-078212	Oryza glumaepatula	30.00	1.60e-01	28.10
IUUC-Oin-079754	Oryza indica	30.00	7.00e-02	29.30
IUUC-Oni-082763	Oryza nivara	43.33	2.70e-01	27.30
IUUC-Oru-084209	Oryza rufipogon	43.33	2.70e-01	27.30
IUUC-Pno-095041	Phaeosphaeria nodorum	26.63	2.00e-14	70.90
IUUC-Ppa-095993	Physcomitrella patens	24.68	1.40e-02	33.50
IUUC-Ptt-103897	Puccinia triticina	43.48	3.70e-01	27.70
IUUC-Pte-104019	Pyrenophora teres	28.01	2.00e-24	104.00
IUUC-Pyt-104814	Pyrenophora triticirepentis	26.79	1.00e-14	71.60
IUUC-Sha-107451	Sarcophilus harrisii	30.00	3.10e-02	32.00
IUUC-Sja-108006	Schizosaccharomyces japonicus	32.61	3.00e-48	183.00
IUUC-Spo-108098	Schizosaccharomyces pombe	31.87	1.00e-52	197.00
IUUC-Ssl-108660	Sclerotinia sclerotiorum	28.93	7.00e-45	172.00
IUUC-Sly-111001	Solanum lycopersicum	34.48	9.00e-01	26.20
IUUC-Tgu-116516	Taeniopygia guttata	42.86	2.30e-02	31.60
IUUC-Tme-127211	Tuber melanosporum	35.39	3.00e-50	190.00
IUUC-Uma-129392	Ustilago maydis	34.55	1.20e-02	32.70
IUUC-Vda-129739	Verticillium dahliae	23.08	1.20e-02	32.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence