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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Sce-106309
UUCD1 version UUC-SaC-00059
Ensembl Protein ID YDR313C
UniProt Accession Q06651; D6VSU2; Q6Q5S5; PIB1_YEAST
Genbank Protein ID AAB64749.1; AAS56068.1; DAA12152.1
Protein Name E3 ubiquitin-protein ligase PIB1; Phosphatidylinositol 3-phosphate-binding protein 1; RING-type E3 ubiquitin transferase PIB1
Genbank Nucleotide ID U28374; AY557742; BK006938
Gene Name PIB1; YDR313C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YDR313C YDR313C YDR313C
Annotation
mRNA Expression
GEOFFGED
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
CPLMdbPAFBioGRID
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 19912579
Classification
Family E-value Score Start End
E3 activity/RING/RING 1.60e-05 23.8 225 268
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkw............p 30
           C+iC+e +   ++ +  l C  vfh +C+++w             
   Q: 225  CPICFENMepgEK-VGRLECLCVFHYKCIKNWfhkraqmtaaqkG 268
           ********55433.66688*************5444443333332 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Functions as an E3 ubiquitin-protein ligase. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
 Functions as an E3 ubiquitin-protein ligase. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
Protein Sequence
(Fasta)
MVIKEDCINN LARWQADEEA HSCFQCKTNF SFLVRRHHCR CCGRIFCSSC TENFVNYNKK 60
RVHALQKKNS DVESPPYRTC NECYDNLLHL NLLVSSTNRD VRLSQTSVPP NALALSAPDS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106309|E3,RING|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTTATTA AAGAGGACTG TATCAATAAT CTTGCCAGGT GGCAGGCAGA CGAGGAAGCT 60
CACAGCTGTT TTCAATGCAA GACGAACTTT TCGTTTCTCG TAAGAAGACA CCATTGTAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106309|E3,RING|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0926--Vacuole
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50178--ZF_FYVE
PS50089--ZF_RING_2
Pfam

PF01363--FYVE
PF13639--zf-RING_2
SMART

SM00064--FYVE
SM00184--RING
Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005770--C:late endosome
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
KEGG sce:YDR313C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001622 Ailuropoda melanoleuca 58.14 1.00e-11 64.30
IUUC-Atr-003065 Amborella trichopoda 32.47 3.00e-07 48.90
IUUC-Apl-004173 Anas platyrhynchos 55.81 3.00e-12 65.50
IUUC-Aly-006441 Arabidopsis lyrata 28.89 7.00e-07 47.80
IUUC-Ago-007798 Ashbya gossypii 41.58 3.00e-59 219.00
IUUC-Acl-008261 Aspergillus clavatus 32.23 2.00e-13 68.20
IUUC-Afl-008724 Aspergillus flavus 45.83 1.00e-10 58.90
IUUC-Afu-008835 Aspergillus fumigatus 32.77 2.00e-12 65.50
IUUC-Ang-009666 Aspergillus niger 32.77 7.00e-12 63.50
IUUC-Ate-010331 Aspergillus terreus 30.25 1.00e-12 65.50
IUUC-Ame-010798 Astyanax mexicanus 42.25 2.00e-11 61.20
IUUC-Bgr-012049 Blumeria graminis 52.08 2.00e-09 55.50
IUUC-Bta-012394 Bos taurus 58.14 9.00e-12 64.30
IUUC-Bol-015203 Brassica oleracea 36.00 2.00e-08 53.50
IUUC-Cel-018347 Caenorhabditis elegans 50.00 2.00e-09 53.50
IUUC-Cja-019711 Callithrix jacchus 60.47 2.00e-12 66.60
IUUC-Cfa-020392 Canis familiaris 53.49 4.00e-11 62.40
IUUC-Cpo-021456 Cavia porcellus 52.08 2.00e-11 63.20
IUUC-Csa-023192 Chlorocebus sabaeus 58.14 5.00e-12 65.50
IUUC-Cin-025162 Ciona intestinalis 48.84 3.00e-10 56.60
IUUC-Csv-026373 Ciona savignyi 48.84 1.00e-10 57.80
IUUC-Cgl-026728 Colletotrichum gloeosporioides 51.06 9.00e-11 59.70
IUUC-Cme-027313 Cyanidioschyzon merolae 54.29 1.00e-07 48.50
IUUC-Dre-027779 Danio rerio 43.66 1.00e-11 63.90
IUUC-Dno-029277 Dasypus novemcinctus 42.67 5.00e-12 65.90
IUUC-Dse-031322 Dothistroma septosporum 46.15 6.00e-12 63.50
IUUC-Eca-033806 Equus caballus 60.00 1.00e-10 60.80
IUUC-Fca-035563 Felis catus 60.47 7.00e-12 64.70
IUUC-Fal-036657 Ficedula albicollis 55.81 6.00e-12 65.50
IUUC-Fox-038020 Fusarium oxysporum 35.96 4.00e-11 60.80
IUUC-Fso-038176 Fusarium solani 29.32 2.00e-08 52.40
IUUC-Gmo-038911 Gadus morhua 42.25 5.00e-12 65.50
IUUC-Ggr-039766 Gaeumannomyces graminis 50.00 3.00e-10 58.20
IUUC-Gga-041069 Gallus gallus 53.49 1.00e-11 63.90
IUUC-Gac-042183 Gasterosteus aculeatus 40.85 4.00e-11 62.40
IUUC-Gma-044193 Glycine max 43.10 2.00e-07 47.80
IUUC-Ggo-045276 Gorilla gorilla 60.47 2.00e-12 66.60
IUUC-Hsa-046982 Homo sapiens 60.47 2.00e-12 66.60
IUUC-Hvu-047529 Hordeum vulgare 25.33 6.00e-05 41.60
IUUC-Itr-048929 Ictidomys tridecemlineatus 60.47 5.00e-12 65.50
IUUC-Kpa-049401 Komagataella pastoris 31.78 1.00e-29 120.00
IUUC-Lch-049451 Latimeria chalumnae 54.76 3.00e-11 63.20
IUUC-Lpe-051482 Leersia perrieri 33.33 8.00e-07 47.80
IUUC-Loc-052441 Lepisosteus oculatus 43.06 3.00e-12 66.20
IUUC-Lma-053072 Leptosphaeria maculans 44.00 3.00e-10 58.20
IUUC-Laf-053370 Loxodonta africana 60.47 2.00e-12 66.60
IUUC-Mcc-054975 Macaca mulatta 58.14 4.00e-12 65.50
IUUC-Meu-056668 Macropus eugenii 53.49 3.00e-11 62.80
IUUC-Mor-056945 Magnaporthe oryzae 38.46 4.00e-10 58.20
IUUC-Mpo-057355 Magnaporthe poae 50.00 2.00e-10 58.50
IUUC-Mtr-057727 Medicago truncatula 44.00 3.00e-09 52.00
IUUC-Mvi-060501 Microbotryum violaceum 26.24 3.00e-22 99.00
IUUC-Mmr-061339 Microcebus murinus 60.47 2.00e-12 66.60
IUUC-Mdo-063054 Monodelphis domestica 55.81 2.00e-11 63.20
IUUC-Mlu-067157 Myotis lucifugus 57.50 6.00e-10 58.50
IUUC-Nfi-068593 Neosartorya fischeri 32.77 3.00e-12 64.70
IUUC-Ncr-068662 Neurospora crassa 50.00 3.00e-10 58.50
IUUC-Nle-069695 Nomascus leucogenys 60.47 2.00e-12 66.60
IUUC-Ont-072336 Oreochromis niloticus 54.76 1.00e-11 64.30
IUUC-Oan-073536 Ornithorhynchus anatinus 55.81 2.00e-11 63.50
IUUC-Obr-076325 Oryza brachyantha 33.33 3.00e-08 50.80
IUUC-Ogl-077843 Oryza glaberrima 31.48 1.00e-06 45.40
IUUC-Ogu-078817 Oryza glumaepatula 34.78 1.00e-05 43.50
IUUC-Oin-079102 Oryza indica 31.48 1.00e-06 45.40
IUUC-Ome-081686 Oryza meridionalis 34.78 1.00e-05 43.50
IUUC-Opu-084137 Oryza punctata 34.78 1.00e-05 43.50
IUUC-Oru-085013 Oryza rufipogon 34.78 1.00e-05 43.50
IUUC-Osa-085597 Oryza sativa 34.78 1.00e-05 43.50
IUUC-Ola-086470 Oryzias latipes 48.84 1.00e-09 57.80
IUUC-Oga-088658 Otolemur garnettii 60.47 2.00e-12 67.00
IUUC-Oar-089316 Ovis aries 55.81 2.00e-11 63.20
IUUC-Ptr-091653 Pan troglodytes 60.47 2.00e-12 66.60
IUUC-Pan-092033 Papio anubis 58.14 5.00e-12 65.50
IUUC-Psi-093520 Pelodiscus sinensis 51.16 5.00e-11 60.50
IUUC-Pfo-096903 Poecilia formosa 57.14 1.00e-11 63.90
IUUC-Pab-098777 Pongo abelii 60.47 2.00e-12 66.60
IUUC-Pop-099121 Populus trichocarpa 31.17 2.00e-07 50.10
IUUC-Ppe-101345 Prunus persica 27.12 3.00e-08 52.40
IUUC-Pva-102241 Pteropus vampyrus 57.50 2.00e-10 60.10
IUUC-Pte-104063 Pyrenophora teres 46.00 7.00e-11 60.10
IUUC-Pyt-104423 Pyrenophora triticirepentis 29.08 2.00e-08 52.00
IUUC-Rno-104949 Rattus norvegicus 60.00 4.00e-10 58.90
IUUC-Sha-106591 Sarcophilus harrisii 53.49 3.00e-11 62.80
IUUC-Sja-107832 Schizosaccharomyces japonicus 27.24 1.00e-22 97.40
IUUC-Spo-108288 Schizosaccharomyces pombe 24.09 4.00e-20 89.40
IUUC-Ssl-108602 Sclerotinia sclerotiorum 60.00 1.00e-09 55.50
IUUC-Smo-109212 Selaginella moellendorffii 36.76 4.00e-08 50.40
IUUC-Sit-109917 Setaria italica 33.33 6.00e-07 47.80
IUUC-Sly-110961 Solanum lycopersicum 31.17 9.00e-06 44.30
IUUC-Stu-112166 Solanum tuberosum 25.98 5.00e-09 55.10
IUUC-Sre-115192 Sporisorium reilianum 29.25 4.00e-28 118.00
IUUC-Ssc-115324 Sus scrofa 44.00 3.00e-12 65.90
IUUC-Tgu-116887 Taeniopygia guttata 55.81 5.00e-12 65.50
IUUC-Tru-118394 Takifugu rubripes 50.00 1.00e-10 60.50
IUUC-Tsy-119577 Tarsius syrichta 60.47 3.00e-12 66.20
IUUC-Tni-119998 Tetraodon nigroviridis 39.19 3.00e-11 62.80
IUUC-Tre-122233 Trichoderma reesei 34.23 4.00e-07 47.80
IUUC-Tvi-122664 Trichoderma virens 28.67 3.00e-22 97.80
IUUC-Tme-127002 Tuber melanosporum 39.71 2.00e-10 58.50
IUUC-Ttr-128386 Tursiops truncatus 58.14 1.00e-11 64.30
IUUC-Uma-129459 Ustilago maydis 29.41 2.00e-27 115.00
IUUC-Vda-129847 Verticillium dahliae 33.90 1.00e-08 52.80
IUUC-Xma-133201 Xiphophorus maculatus 57.14 2.00e-11 63.50
IUUC-Yli-134502 Yarrowia lipolytica 29.15 2.00e-25 106.00
Created Date 25-Jun-2017

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