iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-089155

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03154396

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013860.2	ENSOGAT00000013870.2	ENSOGAP00000012420.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_UBP	3.70e-25	88.0	1127	1187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_UBP

   S: 2    kcsvcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhplvlslstlsvycYacddyvhr 62
            c++c++ +++W+cL+c++v+CGRy +gH+l+Hy ++ hplvls+ +lsv+cY+c++yvh+
   Q: 1127 PCEDCGSLQENWVCLSCYQVYCGRYINGHMLQHYGDSGHPLVLSYVDLSVWCYDCQSYVHH 1187
           6**********************************************************97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

QNRSRDEVYP TMTSTGQDST TTRQRRSRHS PQVPPPDFSV TSKRSIKKGA APHSSPNLAE 60
VKKKGKMKKL GQATEQDLIL GLRGMDLNLE AKPLSGTGLV LDEQLNEFHC LWDDSFPEGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAACCGCA GCAGGGACGA AGTCTACCCA ACCATGACCT CCACCGGCCA GGATTCCACC 60
ACAACCAGAC AGCGAAGGAG TAGGCACAGC CCTCAGGTGC CCCCACCCGA TTTCAGTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	42.68	2.00e-72	267.00
IUUC-Aml-002087	Ailuropoda melanoleuca	78.48	0.00e+00	1824.00
IUUC-Atr-002745	Amborella trichopoda	39.22	5.00e-81	295.00
IUUC-Aca-004303	Anolis carolinensis	49.96	0.00e+00	1117.00
IUUC-Aly-006432	Arabidopsis lyrata	44.51	5.00e-79	288.00
IUUC-Ath-007355	Arabidopsis thaliana	44.81	2.00e-82	300.00
IUUC-Ago-007972	Ashbya gossypii	40.49	5.00e-80	291.00
IUUC-Acl-008187	Aspergillus clavatus	44.19	9.00e-82	298.00
IUUC-Afl-008399	Aspergillus flavus	47.03	5.00e-48	185.00
IUUC-Afu-008954	Aspergillus fumigatus	39.95	8.00e-72	264.00
IUUC-Ani-009142	Aspergillus nidulans	41.64	1.00e-75	278.00
IUUC-Ang-009522	Aspergillus niger	34.49	5.00e-47	182.00
IUUC-Aor-010069	Aspergillus oryzae	42.78	4.00e-75	275.00
IUUC-Ate-010291	Aspergillus terreus	41.42	8.00e-83	301.00
IUUC-Ame-010780	Astyanax mexicanus	50.75	0.00e+00	773.00
IUUC-Bta-013052	Bos taurus	80.49	0.00e+00	1428.00
IUUC-Bci-013789	Botrytis cinerea	40.40	1.00e-73	271.00
IUUC-Bdi-014007	Brachypodium distachyon	42.38	1.00e-81	297.00
IUUC-Bol-015468	Brassica oleracea	42.28	7.00e-81	295.00
IUUC-Bra-016680	Brassica rapa	42.53	1.00e-81	297.00
IUUC-Cel-018220	Caenorhabditis elegans	38.17	4.00e-146	512.00
IUUC-Cja-019473	Callithrix jacchus	79.88	0.00e+00	1830.00
IUUC-Cfa-020263	Canis familiaris	77.82	0.00e+00	1775.00
IUUC-Cpo-021691	Cavia porcellus	77.97	0.00e+00	1775.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	55.45	2.00e-53	202.00
IUUC-Csa-024223	Chlorocebus sabaeus	84.95	0.00e+00	1957.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	39.02	4.00e-74	272.00
IUUC-Cne-026978	Cryptococcus neoformans	44.86	3.00e-84	306.00
IUUC-Dre-028820	Danio rerio	56.48	0.00e+00	890.00
IUUC-Dno-029160	Dasypus novemcinctus	68.41	0.00e+00	1536.00
IUUC-Dor-030859	Dipodomys ordii	69.80	0.00e+00	1639.00
IUUC-Dse-031186	Dothistroma septosporum	41.19	5.00e-76	279.00
IUUC-Dme-031963	Drosophila melanogaster	45.27	0.00e+00	674.00
IUUC-Ete-032279	Echinops telfairi	66.90	1.00e-150	527.00
IUUC-Eca-033842	Equus caballus	81.57	0.00e+00	1879.00
IUUC-Eeu-034487	Erinaceus europaeus	77.04	1.00e-153	537.00
IUUC-Fca-036430	Felis catus	77.74	0.00e+00	1744.00
IUUC-Fox-038067	Fusarium oxysporum	40.98	5.00e-76	278.00
IUUC-Fso-038263	Fusarium solani	39.57	2.00e-77	283.00
IUUC-Ggr-040062	Gaeumannomyces graminis	40.53	1.00e-71	264.00
IUUC-Gma-043738	Glycine max	45.71	4.00e-84	305.00
IUUC-Ggo-045022	Gorilla gorilla	85.11	0.00e+00	1968.00
IUUC-Hsa-046904	Homo sapiens	84.78	0.00e+00	1959.00
IUUC-Hvu-047285	Hordeum vulgare	44.92	5.00e-80	291.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	78.70	0.00e+00	1844.00
IUUC-Kpa-049281	Komagataella pastoris	40.74	1.00e-80	294.00
IUUC-Lch-050330	Latimeria chalumnae	46.33	0.00e+00	942.00
IUUC-Lpe-051214	Leersia perrieri	43.30	2.00e-83	303.00
IUUC-Lma-053263	Leptosphaeria maculans	43.98	5.00e-84	305.00
IUUC-Laf-053386	Loxodonta africana	73.07	0.00e+00	1677.00
IUUC-Mcc-055530	Macaca mulatta	85.20	0.00e+00	1951.00
IUUC-Meu-056442	Macropus eugenii	67.44	0.00e+00	938.00
IUUC-Mor-057095	Magnaporthe oryzae	38.51	1.00e-81	297.00
IUUC-Mpo-057389	Magnaporthe poae	43.02	2.00e-72	266.00
IUUC-Mtr-058463	Medicago truncatula	43.73	2.00e-84	306.00
IUUC-Mla-059143	Melampsora laricipopulina	42.86	3.00e-77	283.00
IUUC-Mmr-060637	Microcebus murinus	88.93	0.00e+00	2098.00
IUUC-Mdo-062198	Monodelphis domestica	66.34	0.00e+00	1029.00
IUUC-Mmu-063346	Mus musculus	72.48	0.00e+00	1672.00
IUUC-Mac-064630	Musa acuminata	45.29	6.00e-80	291.00
IUUC-Mpu-065884	Mustela putorius furo	78.36	0.00e+00	1816.00
IUUC-Mlu-068117	Myotis lucifugus	76.32	0.00e+00	1741.00
IUUC-Nfi-068404	Neosartorya fischeri	43.67	7.00e-82	298.00
IUUC-Ncr-068672	Neurospora crassa	42.28	6.00e-79	288.00
IUUC-Nle-069868	Nomascus leucogenys	92.15	0.00e+00	744.00
IUUC-Opr-071074	Ochotona princeps	69.02	0.00e+00	1110.00
IUUC-Ont-072246	Oreochromis niloticus	45.85	0.00e+00	926.00
IUUC-Oan-072911	Ornithorhynchus anatinus	60.07	1.00e-101	364.00
IUUC-Ocu-074627	Oryctolagus cuniculus	77.43	0.00e+00	1859.00
IUUC-Oba-075489	Oryza barthii	45.54	1.00e-81	297.00
IUUC-Obr-076150	Oryza brachyantha	42.78	3.00e-82	299.00
IUUC-Ogl-077437	Oryza glaberrima	43.18	2.00e-82	300.00
IUUC-Ogu-078370	Oryza glumaepatula	43.18	6.00e-83	301.00
IUUC-Oin-079210	Oryza indica	43.45	4.00e-83	302.00
IUUC-Olo-080971	Oryza longistaminata	47.14	2.00e-72	266.00
IUUC-Oni-082031	Oryza nivara	43.45	6.00e-83	301.00
IUUC-Opu-083471	Oryza punctata	45.12	7.00e-82	298.00
IUUC-Oru-084755	Oryza rufipogon	43.18	7.00e-83	301.00
IUUC-Osa-085447	Oryza sativa	43.18	8.00e-83	301.00
IUUC-Oar-089620	Ovis aries	72.75	0.00e+00	1644.00
IUUC-Ptr-090812	Pan troglodytes	90.87	0.00e+00	1281.00
IUUC-Pan-092340	Papio anubis	85.28	0.00e+00	1956.00
IUUC-Pma-094386	Petromyzon marinus	53.55	0.00e+00	813.00
IUUC-Pno-095131	Phaeosphaeria nodorum	48.06	1.00e-71	263.00
IUUC-Ppa-095550	Physcomitrella patens	46.70	6.00e-89	322.00
IUUC-Pfo-096110	Poecilia formosa	52.70	0.00e+00	711.00
IUUC-Pab-098422	Pongo abelii	84.10	0.00e+00	1925.00
IUUC-Pop-099174	Populus trichocarpa	41.67	6.00e-77	281.00
IUUC-Pca-100833	Procavia capensis	70.45	0.00e+00	1536.00
IUUC-Ppe-101644	Prunus persica	44.01	5.00e-84	305.00
IUUC-Pva-102410	Pteropus vampyrus	71.61	0.00e+00	1590.00
IUUC-Ptt-103841	Puccinia triticina	39.00	8.00e-76	278.00
IUUC-Pte-104383	Pyrenophora teres	43.05	5.00e-80	292.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.32	3.00e-80	292.00
IUUC-Rno-105131	Rattus norvegicus	72.29	0.00e+00	1667.00
IUUC-Sce-106274	Saccharomyces cerevisiae	36.25	8.00e-76	278.00
IUUC-Sha-106661	Sarcophilus harrisii	55.23	0.00e+00	797.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	41.81	1.00e-84	307.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.75	7.00e-85	308.00
IUUC-Smo-109615	Selaginella moellendorffii	44.10	5.00e-83	301.00
IUUC-Sit-110160	Setaria italica	42.70	2.00e-77	283.00
IUUC-Sly-111164	Solanum lycopersicum	39.56	8.00e-78	284.00
IUUC-Stu-112685	Solanum tuberosum	37.44	8.00e-70	258.00
IUUC-Sar-113692	Sorex araneus	66.11	0.00e+00	751.00
IUUC-Sbi-114301	Sorghum bicolor	43.18	6.00e-77	281.00
IUUC-Sre-115013	Sporisorium reilianum	40.87	1.00e-77	284.00
IUUC-Ssc-115724	Sus scrofa	75.25	0.00e+00	1631.00
IUUC-Tgu-116605	Taeniopygia guttata	48.71	0.00e+00	676.00
IUUC-Tru-117614	Takifugu rubripes	57.01	0.00e+00	845.00
IUUC-Tsy-118807	Tarsius syrichta	75.50	0.00e+00	1013.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.39	0.00e+00	787.00
IUUC-Tca-121312	Theobroma cacao	44.32	4.00e-81	295.00
IUUC-Tre-121930	Trichoderma reesei	41.09	2.00e-78	286.00
IUUC-Tvi-122373	Trichoderma virens	41.60	3.00e-79	289.00
IUUC-Tae-123064	Triticum aestivum	43.28	4.00e-79	288.00
IUUC-Tme-127027	Tuber melanosporum	41.58	6.00e-67	248.00
IUUC-Tbe-127675	Tupaia belangeri	61.42	3.00e-119	423.00
IUUC-Ttr-128411	Tursiops truncatus	74.75	0.00e+00	1724.00
IUUC-Uma-129408	Ustilago maydis	45.45	2.00e-71	263.00
IUUC-Vda-129994	Verticillium dahliae	38.38	1.00e-71	264.00
IUUC-Vpa-130525	Vicugna pacos	79.26	2.00e-62	233.00
IUUC-Vvi-131038	Vitis vinifera	41.78	5.00e-82	298.00
IUUC-Xtr-132618	Xenopus tropicalis	57.18	0.00e+00	935.00
IUUC-Xma-133730	Xiphophorus maculatus	49.24	0.00e+00	691.00
IUUC-Yli-134680	Yarrowia lipolytica	36.28	8.00e-83	301.00
IUUC-Zma-135110	Zea mays	42.86	9.00e-79	287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence