iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108112

UUCD1 version

UUC-ScP-00034

Ensembl Protein ID

SPCC338.16.1:pep

UniProt Accession

O74991; POF3_SCHPO

Genbank Protein ID

BAA84529.1; CAA19347.1

Protein Name

F-box/TPR repeat protein pof3

Genbank Nucleotide ID

AB032411; CU329672

Gene Name

pof3; SPCC338.16

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPCC338.16	SPCC338.16.1	SPCC338.16.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	20230746; 16997270; 11809834

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.0002	19.5	134	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 101  glldrlpeeilveilklldkeellraarvcrrwqelas.qk 140
           +l+  lp e+l+ il+ l+ ++++++ +vc++w+ +++ ++
   Q: 134  DLFRILPREVLLCILQQLNFKSIVQCMQVCKHWRDCIKkEP 174
           567789****************************7666144 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Has a role in substrate recognition in the Skp1-Cullin-1/Cdc53-F-box (SCF) ubiquitin ligase complex. Required for the maintenance of telomere length and transcriptional silencing at the telomere. Also required for chromosome segregation.

Protein Sequence
(Fasta)

MNNYQVKAIK EKTQQYLSKR KFEDALTFIT KTIEQEPNPT IDLFELRAQV YEKSGQYSQA 60
ELDAKRMIHL NARNARGYLR LGKLLQLDGF DKKADQLYTQ GLRMVHKMDP LRPVLKKVSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTAACTTA CTCCATAAAG CTTGCGACTA CGAAAGCATA ATATATACCT CAAAAAGGAT 60
ATCGAGGTTC TTAAAATACG GTTCATTGGA AGCTATATGG GAGGTTTATG TTTATGTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0496--Mitochondrion
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0833--Ubl conjugation pathway

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR001810--F-box_dom
IPR032675--L_dom-like
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat

PROSITE

PS50181--FBOX
PS50293--TPR_REGION

Pfam

PF00646--F-box

SMART

SM00256--FBOX
SM00028--TPR

Gene Ontology

GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0030674--F:protein binding, bridging
GO:1903464--P:negative regulation of mitotic cell cycle DNA replication
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006355--P:regulation of transcription, DNA-templated
GO:0000723--P:telomere maintenance
GO:0006351--P:transcription, DNA-templated

KEGG

spo:SPCC338.16

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007793	Ashbya gossypii	23.08	5.00e-10	57.80
IUUC-Acl-008351	Aspergillus clavatus	31.25	3.00e-20	91.30
IUUC-Afl-008600	Aspergillus flavus	33.10	9.00e-12	62.80
IUUC-Ani-009209	Aspergillus nidulans	27.68	2.00e-18	85.50
IUUC-Ang-009799	Aspergillus niger	32.68	4.00e-16	77.80
IUUC-Aor-010149	Aspergillus oryzae	42.00	6.00e-04	37.00
IUUC-Ate-010543	Aspergillus terreus	31.71	1.00e-17	82.80
IUUC-Bgr-012086	Blumeria graminis	24.92	4.00e-12	64.30
IUUC-Bci-013665	Botrytis cinerea	29.46	8.00e-17	80.10
IUUC-Cja-019100	Callithrix jacchus	30.59	7.00e-05	42.40
IUUC-Csv-026124	Ciona savignyi	29.21	2.00e-04	37.40
IUUC-Cgl-026584	Colletotrichum gloeosporioides	26.53	2.00e-08	52.40
IUUC-Dse-031168	Dothistroma septosporum	25.97	2.00e-11	62.40
IUUC-Fox-037939	Fusarium oxysporum	26.53	2.00e-07	48.90
IUUC-Fso-038167	Fusarium solani	32.06	6.00e-11	60.50
IUUC-Ggr-039955	Gaeumannomyces graminis	29.60	3.00e-07	48.10
IUUC-Gma-044203	Glycine max	47.22	3.00e-04	37.40
IUUC-Kpa-049108	Komagataella pastoris	24.62	4.00e-07	48.10
IUUC-Lma-053184	Leptosphaeria maculans	30.00	9.00e-19	86.30
IUUC-Mor-057081	Magnaporthe oryzae	27.40	1.00e-03	36.20
IUUC-Mpo-057619	Magnaporthe poae	28.24	3.00e-06	45.10
IUUC-Mla-058833	Melampsora laricipopulina	28.57	2.00e-10	58.50
IUUC-Mvi-060502	Microbotryum violaceum	22.83	8.00e-08	50.10
IUUC-Mac-065661	Musa acuminata	35.29	5.00e-03	33.90
IUUC-Nfi-068490	Neosartorya fischeri	29.38	1.00e-18	86.30
IUUC-Ola-086847	Oryzias latipes	32.93	1.00e-04	40.00
IUUC-Psi-093680	Pelodiscus sinensis	33.33	8.00e-04	38.50
IUUC-Pno-095042	Phaeosphaeria nodorum	28.98	3.00e-19	87.40
IUUC-Ppa-095293	Physcomitrella patens	30.77	1.20e-02	32.70
IUUC-Pop-100065	Populus trichocarpa	34.67	1.00e-04	38.90
IUUC-Pgr-103685	Puccinia graminis	35.90	4.00e-03	34.30
IUUC-Ptt-103858	Puccinia triticina	28.75	1.10e-02	33.50
IUUC-Pte-104379	Pyrenophora teres	31.40	6.00e-19	87.00
IUUC-Pyt-104626	Pyrenophora triticirepentis	31.40	3.00e-20	91.30
IUUC-Sja-107999	Schizosaccharomyces japonicus	44.02	6.00e-137	478.00
IUUC-Ssl-108627	Sclerotinia sclerotiorum	27.98	2.00e-16	78.60
IUUC-Ssc-115530	Sus scrofa	30.59	9.00e-05	41.20
IUUC-Tru-118283	Takifugu rubripes	33.33	4.00e-05	42.00
IUUC-Tca-121064	Theobroma cacao	54.55	5.00e-05	40.00
IUUC-Tre-122056	Trichoderma reesei	25.48	2.00e-05	42.70
IUUC-Tvi-122653	Trichoderma virens	25.32	3.00e-03	35.40
IUUC-Tme-126968	Tuber melanosporum	27.88	2.00e-10	57.80
IUUC-Vvi-131582	Vitis vinifera	27.45	3.00e-04	38.10
IUUC-Yli-134623	Yarrowia lipolytica	26.24	1.00e-09	55.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence