iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096562

Ensembl Protein ID

ENSPFOP00000017618.2

UniProt Accession

A0A087YHW5; A0A087YHW5_POEFO

Genbank Protein ID

ENSPFOP00000017618

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01012239

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000017442.2	ENSPFOT00000029413.1	ENSPFOP00000024527.1
ENSPFOG00000017442.2	ENSPFOT00000017640.2	ENSPFOP00000017618.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.90e-97	326.2	426	762

Active Site

Position(s)	Description	Evidence
730	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           dlkk+l+v+fvgE+gld+gG+t+e++ ll+++++++d+g+f + ++++++++ + +s     ++ + F+++G+l+g+a++++  ld+++
   Q: 426  DLKKKLRVTFVGEAGLDMGGLTKEWFLLLVRQIFHTDYGMFSFMKDSRCHWFSSWKS-----DNYSEFQMVGTLMGLAVYNSIALDIHF 509
           89*************************************************988777.....789************************ PP
   S: 93   sksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
           +  +y++ll+                 +l+dl++v+p+l++ l e++++ e ++ee  + ltf+v +e++g +k+++Lkp G++ipVt+
   Q: 510  PLYCYRKLLTPptvpsdpnafvgtaTATLDDLQQVMPDLAHGLAELLSY-EGNVEED-FYLTFQVFQEEMGVVKSYNLKPAGDKIPVTK 596
           ********9996565555555555559*********************9.6788885.******************************* PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleef 256
           +N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+++l+k ++y+ gy++ + ++++Fw+v+ +f
   Q: 597  QNRKEYVQLYIDFLLNKSIYKQFAAFYHGFHSVCASDALMLLRPEEVEMLVCGSPELDMSALQKAAQYE-GYSKMDATVRFFWDVVLAF 684
           ********************************************************************5.5****************** PP
   S: 257  sseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
             e +k++L+F+Tgs+r+P+gG+a+l+   f i k d   d+lP s+TCfn+++LP+Y + ++lk+kL++Ai++++gF+l+
   Q: 685  PLELQKKLLHFATGSDRVPVGGMADLN---FKICKiDVPADWLPVSHTCFNQICLPPYRTRKELKHKLTIAISNAEGFGLE 762
           ***************************...5555546788**************************************985 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MDGEHSALSG VERERERLPP IYTSSPPVLG RGPKQPFPSL GTFISTLSQR RDAGGRGFAI 60
GIGGPLTGPL GIRHTVRELP PICSDVRQKQ RLSIDTLPQE VKAPFPCDPV IPLRTKTTKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTTTGCTC TTTTATTTTG AATCCTGTTC TCCCCTCTCT CTGCTGGTGA CGCTGGGTCT 60
CCAGGCGCCT CCTCCTCTTC ATCCTCCTCC TCCTCCCTCC AAACATGGCG CCGGCTCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	72.22	0.00e+00	1135.00
IUUC-Apl-003589	Anas platyrhynchos	73.43	0.00e+00	1130.00
IUUC-Aca-004350	Anolis carolinensis	70.30	0.00e+00	1071.00
IUUC-Ago-007908	Ashbya gossypii	34.52	2.00e-82	300.00
IUUC-Acl-008288	Aspergillus clavatus	34.21	5.00e-93	336.00
IUUC-Afl-008402	Aspergillus flavus	34.00	4.00e-88	319.00
IUUC-Afu-008762	Aspergillus fumigatus	33.33	1.00e-91	331.00
IUUC-Ani-009176	Aspergillus nidulans	34.55	7.00e-90	325.00
IUUC-Ang-009791	Aspergillus niger	34.21	2.00e-89	323.00
IUUC-Aor-009921	Aspergillus oryzae	33.83	1.00e-87	317.00
IUUC-Ate-010295	Aspergillus terreus	34.98	2.00e-96	347.00
IUUC-Ame-010660	Astyanax mexicanus	82.27	2.00e-152	531.00
IUUC-Bgr-011981	Blumeria graminis	32.31	7.00e-86	312.00
IUUC-Bta-012945	Bos taurus	71.18	0.00e+00	1103.00
IUUC-Bci-013697	Botrytis cinerea	37.39	2.00e-78	287.00
IUUC-Cja-019263	Callithrix jacchus	70.73	0.00e+00	1090.00
IUUC-Cfa-020486	Canis familiaris	76.55	0.00e+00	1072.00
IUUC-Cpo-021755	Cavia porcellus	75.81	0.00e+00	1120.00
IUUC-Csa-023814	Chlorocebus sabaeus	70.94	0.00e+00	1030.00
IUUC-Cho-024980	Choloepus hoffmanni	59.18	0.00e+00	871.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	38.68	2.00e-89	324.00
IUUC-Dre-028551	Danio rerio	78.03	0.00e+00	1189.00
IUUC-Dno-029497	Dasypus novemcinctus	73.48	0.00e+00	1045.00
IUUC-Dor-030867	Dipodomys ordii	62.53	0.00e+00	931.00
IUUC-Dse-031239	Dothistroma septosporum	28.70	3.00e-85	310.00
IUUC-Ete-032902	Echinops telfairi	63.99	0.00e+00	923.00
IUUC-Eca-033678	Equus caballus	71.93	0.00e+00	1118.00
IUUC-Eeu-035262	Erinaceus europaeus	62.83	0.00e+00	882.00
IUUC-Fca-035590	Felis catus	72.24	0.00e+00	1135.00
IUUC-Fal-037123	Ficedula albicollis	68.82	0.00e+00	1063.00
IUUC-Fox-037941	Fusarium oxysporum	37.50	1.00e-94	342.00
IUUC-Fso-038388	Fusarium solani	38.90	3.00e-98	353.00
IUUC-Gmo-039553	Gadus morhua	73.32	0.00e+00	928.00
IUUC-Ggr-040110	Gaeumannomyces graminis	38.58	3.00e-92	334.00
IUUC-Gga-040406	Gallus gallus	72.23	0.00e+00	1154.00
IUUC-Gac-042141	Gasterosteus aculeatus	91.74	0.00e+00	1307.00
IUUC-Ggo-045504	Gorilla gorilla	69.95	0.00e+00	1095.00
IUUC-Hsa-045786	Homo sapiens	70.32	0.00e+00	1100.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	70.06	0.00e+00	1012.00
IUUC-Kpa-049152	Komagataella pastoris	30.69	2.00e-72	267.00
IUUC-Lch-049824	Latimeria chalumnae	73.24	0.00e+00	1003.00
IUUC-Loc-052173	Lepisosteus oculatus	75.30	0.00e+00	1151.00
IUUC-Laf-054017	Loxodonta africana	75.84	0.00e+00	1114.00
IUUC-Mcc-055713	Macaca mulatta	73.99	0.00e+00	1087.00
IUUC-Meu-056212	Macropus eugenii	60.19	1.00e-97	350.00
IUUC-Mor-057045	Magnaporthe oryzae	37.79	9.00e-86	312.00
IUUC-Mla-059187	Melampsora laricipopulina	40.00	1.00e-79	290.00
IUUC-Mga-059884	Meleagris gallopavo	66.85	0.00e+00	1010.00
IUUC-Mmr-061344	Microcebus murinus	73.84	0.00e+00	1110.00
IUUC-Mdo-062653	Monodelphis domestica	70.03	0.00e+00	1090.00
IUUC-Mmu-063775	Mus musculus	73.73	0.00e+00	1036.00
IUUC-Mpu-066069	Mustela putorius furo	75.23	0.00e+00	1081.00
IUUC-Mlu-067925	Myotis lucifugus	75.29	0.00e+00	1110.00
IUUC-Nfi-068439	Neosartorya fischeri	33.50	9.00e-91	328.00
IUUC-Ncr-068903	Neurospora crassa	37.18	6.00e-90	326.00
IUUC-Nle-070046	Nomascus leucogenys	74.13	0.00e+00	1107.00
IUUC-Opr-071085	Ochotona princeps	62.75	5.00e-109	388.00
IUUC-Ont-072126	Oreochromis niloticus	91.87	0.00e+00	1456.00
IUUC-Oan-072933	Ornithorhynchus anatinus	75.31	0.00e+00	1033.00
IUUC-Ocu-073800	Oryctolagus cuniculus	75.08	0.00e+00	1068.00
IUUC-Ola-086988	Oryzias latipes	91.85	0.00e+00	1324.00
IUUC-Oga-088117	Otolemur garnettii	76.55	0.00e+00	942.00
IUUC-Oar-089371	Ovis aries	71.56	0.00e+00	1087.00
IUUC-Ptr-090551	Pan troglodytes	73.99	0.00e+00	1087.00
IUUC-Pan-092067	Papio anubis	74.27	0.00e+00	1091.00
IUUC-Psi-092963	Pelodiscus sinensis	70.59	0.00e+00	1069.00
IUUC-Pab-098680	Pongo abelii	70.32	0.00e+00	1098.00
IUUC-Pca-100986	Procavia capensis	60.77	0.00e+00	729.00
IUUC-Pva-102219	Pteropus vampyrus	68.01	0.00e+00	842.00
IUUC-Pgr-103315	Puccinia graminis	34.34	2.00e-87	317.00
IUUC-Ptt-103736	Puccinia triticina	38.94	1.00e-88	322.00
IUUC-Rno-105270	Rattus norvegicus	73.84	0.00e+00	1042.00
IUUC-Sce-106306	Saccharomyces cerevisiae	33.86	1.00e-72	268.00
IUUC-Sha-106819	Sarcophilus harrisii	72.89	0.00e+00	1139.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.81	2.00e-86	313.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	37.14	1.00e-79	292.00
IUUC-Sar-113134	Sorex araneus	64.71	0.00e+00	966.00
IUUC-Ssc-115441	Sus scrofa	72.15	0.00e+00	1104.00
IUUC-Tgu-117166	Taeniopygia guttata	70.76	0.00e+00	1073.00
IUUC-Tsy-118898	Tarsius syrichta	65.29	0.00e+00	871.00
IUUC-Tre-122108	Trichoderma reesei	35.67	6.00e-85	309.00
IUUC-Tvi-122644	Trichoderma virens	36.14	9.00e-90	325.00
IUUC-Tme-127004	Tuber melanosporum	35.08	1.00e-102	369.00
IUUC-Tbe-127292	Tupaia belangeri	61.77	0.00e+00	858.00
IUUC-Ttr-128352	Tursiops truncatus	69.21	0.00e+00	1060.00
IUUC-Vda-129969	Verticillium dahliae	38.90	5.00e-88	320.00
IUUC-Vpa-130218	Vicugna pacos	68.69	0.00e+00	772.00
IUUC-Xtr-132594	Xenopus tropicalis	67.37	0.00e+00	1030.00
IUUC-Xma-134157	Xiphophorus maculatus	98.46	0.00e+00	1326.00
IUUC-Yli-134470	Yarrowia lipolytica	32.15	5.00e-78	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence