iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020746

Ensembl Protein ID

ENSCAFP00000008903.3

UniProt Accession

E2QV84; E2QV84_CANLF

Genbank Protein ID

ENSCAFP00000008903

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014184

Gene Name

VPS36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005932.3	ENSCAFT00000009588.3	ENSCAFP00000008903.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/PH/GLUE	3.10e-74	247.8	1	138

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/PH/GLUE

   S: 1    mdrfvytealLeinetlvirqrsvkiydgdekikfdaGellLtthRLiWirdqkneevtlaipLsavvfieeeaaaigksakivvhlhp 89
           mdrfv+t++lLeinetlvi+qr+v+iydg+ekikfdaG+llL+thRLiW rdqkn+e+++ai+Ls++vfiee+aa+igksakivvhlhp
   Q: 1    MDRFVWTSGLLEINETLVIQQRGVRIYDGEEKIKFDAGTLLLSTHRLIW-RDQKNHECCMAILLSQIVFIEEQAAGIGKSAKIVVHLHP 88
           9************************************************.*************************************** PP
   S: 90   arsdkePGpldsskasyiklsfkekgdiefyskLseeltaRaWeelevse 139
           ++s+kePGp++ssk+syiklsfke+g+iefy++Lsee+t+R+We+++vs+
   Q: 89   PPSNKEPGPFQSSKNSYIKLSFKEHGQIEFYRRLSEEMTQRRWENMPVSQ 138
           ************************************************97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDRFVWTSGL LEINETLVIQ QRGVRIYDGE EKIKFDAGTL LLSTHRLIWR DQKNHECCMA 60
ILLSQIVFIE EQAAGIGKSA KIVVHLHPPP SNKEPGPFQS SKNSYIKLSF KEHGQIEFYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAAATGTG TGCAAACTCT TTAAAGCAGT AATTCTATTT TGGGAAGACA CTCTAAGAAA 60
ATAATCCTTA AAGGCCCAAA AATATATCAG TTGTACAAGT ACTACTATAG GTGTTCCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007286--EAP30
IPR021648--GLUE_dom
IPR011993--PH_dom-like
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS51495--GLUE

Pfam

PF04157--EAP30
PF11605--Vps36_ESCRT-II

Gene Ontology

GO:0005829--C:cytosol
GO:0000814--C:ESCRT II complex
GO:0070062--C:extracellular exosome
GO:0031902--C:late endosome membrane
GO:0005764--C:lysosome
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0043130--F:ubiquitin binding
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000963	Aegilops tauschii	41.36	6.00e-34	137.00
IUUC-Aml-002313	Ailuropoda melanoleuca	98.19	0.00e+00	754.00
IUUC-Atr-003096	Amborella trichopoda	36.05	2.00e-15	76.30
IUUC-Apl-003218	Anas platyrhynchos	88.45	0.00e+00	680.00
IUUC-Aca-004580	Anolis carolinensis	90.41	0.00e+00	700.00
IUUC-Aly-006398	Arabidopsis lyrata	37.32	9.00e-57	214.00
IUUC-Ath-006907	Arabidopsis thaliana	37.90	2.00e-56	213.00
IUUC-Ago-007840	Ashbya gossypii	22.71	5.00e-04	39.70
IUUC-Acl-008117	Aspergillus clavatus	32.30	4.00e-37	149.00
IUUC-Afl-008595	Aspergillus flavus	32.64	5.00e-37	149.00
IUUC-Afu-008918	Aspergillus fumigatus	31.69	1.00e-36	147.00
IUUC-Ani-009206	Aspergillus nidulans	33.54	5.00e-37	149.00
IUUC-Ang-009784	Aspergillus niger	32.72	5.00e-34	139.00
IUUC-Aor-010126	Aspergillus oryzae	32.64	5.00e-37	149.00
IUUC-Ate-010303	Aspergillus terreus	33.23	3.00e-35	143.00
IUUC-Ame-011190	Astyanax mexicanus	84.82	0.00e+00	662.00
IUUC-Bgr-011979	Blumeria graminis	31.96	4.00e-34	139.00
IUUC-Bta-012661	Bos taurus	98.45	0.00e+00	753.00
IUUC-Bci-013982	Botrytis cinerea	33.24	3.00e-34	140.00
IUUC-Bdi-014753	Brachypodium distachyon	40.21	2.00e-50	193.00
IUUC-Bol-015465	Brassica oleracea	42.25	8.00e-49	187.00
IUUC-Bra-016794	Brassica rapa	42.69	6.00e-50	191.00
IUUC-Cel-018514	Caenorhabditis elegans	42.12	2.00e-82	299.00
IUUC-Cja-019285	Callithrix jacchus	97.46	0.00e+00	680.00
IUUC-Cpo-022005	Cavia porcellus	96.61	0.00e+00	681.00
IUUC-Cre-022686	Chlamydomonas reinhardtii	36.02	6.00e-34	139.00
IUUC-Csa-023520	Chlorocebus sabaeus	98.70	0.00e+00	758.00
IUUC-Cho-024957	Choloepus hoffmanni	93.01	0.00e+00	708.00
IUUC-Cin-025575	Ciona intestinalis	47.62	5.00e-08	48.90
IUUC-Csv-025942	Ciona savignyi	53.11	3.00e-108	385.00
IUUC-Cgl-026558	Colletotrichum gloeosporioides	32.44	7.00e-32	132.00
IUUC-Cne-026915	Cryptococcus neoformans	28.30	2.00e-24	107.00
IUUC-Cme-027099	Cyanidioschyzon merolae	25.11	5.00e-12	65.90
IUUC-Dre-027753	Danio rerio	84.55	0.00e+00	660.00
IUUC-Dno-029922	Dasypus novemcinctus	95.85	0.00e+00	738.00
IUUC-Dor-030643	Dipodomys ordii	89.90	0.00e+00	679.00
IUUC-Dse-031368	Dothistroma septosporum	32.39	1.00e-30	127.00
IUUC-Dme-031977	Drosophila melanogaster	45.61	2.00e-94	339.00
IUUC-Ete-033135	Echinops telfairi	73.94	7.00e-139	486.00
IUUC-Eca-033937	Equus caballus	97.46	0.00e+00	685.00
IUUC-Eeu-034483	Erinaceus europaeus	93.01	0.00e+00	736.00
IUUC-Fca-035496	Felis catus	97.74	0.00e+00	682.00
IUUC-Fal-036743	Ficedula albicollis	89.90	0.00e+00	700.00
IUUC-Fox-037685	Fusarium oxysporum	35.24	7.00e-28	119.00
IUUC-Fso-038421	Fusarium solani	31.53	1.00e-29	124.00
IUUC-Gmo-039456	Gadus morhua	79.37	3.00e-175	607.00
IUUC-Ggr-039763	Gaeumannomyces graminis	31.67	6.00e-37	149.00
IUUC-Gga-040556	Gallus gallus	89.12	0.00e+00	689.00
IUUC-Gac-041481	Gasterosteus aculeatus	80.73	4.00e-159	554.00
IUUC-Gma-044185	Glycine max	43.85	3.00e-52	199.00
IUUC-Ggo-044849	Gorilla gorilla	98.96	0.00e+00	759.00
IUUC-Hsa-046228	Homo sapiens	98.96	0.00e+00	759.00
IUUC-Hvu-047858	Hordeum vulgare	37.50	7.00e-14	70.90
IUUC-Itr-048068	Ictidomys tridecemlineatus	94.33	0.00e+00	720.00
IUUC-Kpa-049240	Komagataella pastoris	24.77	4.00e-06	46.20
IUUC-Lch-050293	Latimeria chalumnae	87.74	1.00e-125	442.00
IUUC-Lpe-051363	Leersia perrieri	45.08	2.00e-51	196.00
IUUC-Loc-052866	Lepisosteus oculatus	84.20	0.00e+00	635.00
IUUC-Lma-053139	Leptosphaeria maculans	29.41	1.00e-32	134.00
IUUC-Laf-053881	Loxodonta africana	90.93	0.00e+00	692.00
IUUC-Mcc-055158	Macaca mulatta	98.45	0.00e+00	757.00
IUUC-Meu-056126	Macropus eugenii	74.58	1.00e-135	475.00
IUUC-Mor-057092	Magnaporthe oryzae	31.55	7.00e-34	139.00
IUUC-Mpo-057629	Magnaporthe poae	32.21	6.00e-29	121.00
IUUC-Mtr-058039	Medicago truncatula	44.44	9.00e-53	201.00
IUUC-Mla-058913	Melampsora laricipopulina	31.19	7.00e-25	108.00
IUUC-Mga-059956	Meleagris gallopavo	89.12	0.00e+00	692.00
IUUC-Mvi-060570	Microbotryum violaceum	24.21	2.00e-18	87.40
IUUC-Mmr-061769	Microcebus murinus	97.46	0.00e+00	681.00
IUUC-Mdo-062751	Monodelphis domestica	91.62	0.00e+00	709.00
IUUC-Mmu-063115	Mus musculus	95.60	0.00e+00	743.00
IUUC-Mac-064979	Musa acuminata	35.58	3.00e-52	199.00
IUUC-Mpu-066904	Mustela putorius furo	97.89	2.00e-137	481.00
IUUC-Mlu-067474	Myotis lucifugus	97.15	0.00e+00	742.00
IUUC-Nfi-068588	Neosartorya fischeri	32.30	1.00e-33	138.00
IUUC-Ncr-068855	Neurospora crassa	30.00	1.00e-28	121.00
IUUC-Nle-069660	Nomascus leucogenys	98.19	0.00e+00	753.00
IUUC-Opr-070695	Ochotona princeps	96.11	0.00e+00	738.00
IUUC-Ont-071837	Oreochromis niloticus	83.77	2.00e-174	605.00
IUUC-Oan-072903	Ornithorhynchus anatinus	93.26	0.00e+00	660.00
IUUC-Ocu-074833	Oryctolagus cuniculus	96.89	0.00e+00	750.00
IUUC-Oba-075899	Oryza barthii	45.42	2.00e-51	196.00
IUUC-Obr-076125	Oryza brachyantha	36.24	1.00e-54	206.00
IUUC-Ogl-077538	Oryza glaberrima	50.00	4.00e-32	132.00
IUUC-Ogu-078272	Oryza glumaepatula	45.08	2.00e-51	196.00
IUUC-Oin-079158	Oryza indica	44.35	6.00e-51	194.00
IUUC-Olo-080496	Oryza longistaminata	44.17	1.00e-47	182.00
IUUC-Ome-081440	Oryza meridionalis	44.77	3.00e-49	188.00
IUUC-Oni-083069	Oryza nivara	44.35	6.00e-51	194.00
IUUC-Opu-083838	Oryza punctata	45.53	7.00e-50	190.00
IUUC-Oru-084377	Oryza rufipogon	45.08	2.00e-51	196.00
IUUC-Osa-085976	Oryza sativa	45.08	2.00e-51	196.00
IUUC-Ola-086431	Oryzias latipes	84.82	3.00e-176	610.00
IUUC-Olu-087789	Ostreococcus lucimarinus	39.30	2.00e-39	155.00
IUUC-Oga-089152	Otolemur garnettii	96.63	0.00e+00	741.00
IUUC-Oar-089198	Ovis aries	98.31	0.00e+00	687.00
IUUC-Ptr-091123	Pan troglodytes	98.96	0.00e+00	759.00
IUUC-Pan-092866	Papio anubis	95.09	0.00e+00	728.00
IUUC-Psi-093384	Pelodiscus sinensis	94.04	0.00e+00	725.00
IUUC-Pno-094773	Phaeosphaeria nodorum	31.61	1.00e-27	117.00
IUUC-Ppa-095753	Physcomitrella patens	36.20	4.00e-56	212.00
IUUC-Pfo-096028	Poecilia formosa	83.77	3.00e-176	610.00
IUUC-Pop-098915	Populus trichocarpa	44.86	7.00e-52	197.00
IUUC-Pca-100422	Procavia capensis	93.79	0.00e+00	655.00
IUUC-Ppe-101564	Prunus persica	44.90	3.00e-53	202.00
IUUC-Pva-103019	Pteropus vampyrus	92.49	0.00e+00	701.00
IUUC-Pgr-103670	Puccinia graminis	28.46	2.00e-21	97.80
IUUC-Ptt-103958	Puccinia triticina	27.20	2.00e-20	93.60
IUUC-Pte-104343	Pyrenophora teres	31.90	1.00e-38	154.00
IUUC-Pyt-104554	Pyrenophora triticirepentis	31.68	2.00e-40	160.00
IUUC-Rno-105775	Rattus norvegicus	95.34	0.00e+00	737.00
IUUC-Sha-106468	Sarcophilus harrisii	93.50	0.00e+00	655.00
IUUC-Sja-107850	Schizosaccharomyces japonicus	23.91	7.00e-17	81.60
IUUC-Spo-108225	Schizosaccharomyces pombe	23.37	3.00e-17	83.20
IUUC-Ssl-108412	Sclerotinia sclerotiorum	32.54	9.00e-32	131.00
IUUC-Smo-109001	Selaginella moellendorffii	35.33	6.00e-54	204.00
IUUC-Sit-110126	Setaria italica	34.59	1.00e-49	190.00
IUUC-Sly-110884	Solanum lycopersicum	37.03	2.00e-51	196.00
IUUC-Stu-112573	Solanum tuberosum	35.88	1.00e-51	197.00
IUUC-Sar-113114	Sorex araneus	93.28	3.00e-69	254.00
IUUC-Sbi-114331	Sorghum bicolor	30.41	1.00e-38	154.00
IUUC-Sre-115135	Sporisorium reilianum	23.35	1.00e-10	61.60
IUUC-Ssc-116158	Sus scrofa	98.96	0.00e+00	759.00
IUUC-Tgu-116962	Taeniopygia guttata	89.64	0.00e+00	668.00
IUUC-Tru-117567	Takifugu rubripes	83.51	1.00e-175	608.00
IUUC-Tsy-119357	Tarsius syrichta	81.09	1.00e-165	575.00
IUUC-Tni-120047	Tetraodon nigroviridis	83.09	2.00e-155	541.00
IUUC-Tca-121097	Theobroma cacao	44.86	2.00e-53	203.00
IUUC-Tre-122075	Trichoderma reesei	30.41	3.00e-34	140.00
IUUC-Tvi-122623	Trichoderma virens	32.84	1.00e-40	161.00
IUUC-Tae-123728	Triticum aestivum	43.03	3.00e-50	192.00
IUUC-Tur-125988	Triticum urartu	41.84	8.00e-40	157.00
IUUC-Tme-126936	Tuber melanosporum	31.43	7.00e-35	142.00
IUUC-Tbe-127481	Tupaia belangeri	67.51	5.00e-127	447.00
IUUC-Ttr-128160	Tursiops truncatus	97.15	0.00e+00	735.00
IUUC-Uma-129428	Ustilago maydis	24.83	2.00e-17	84.30
IUUC-Vda-129877	Verticillium dahliae	32.39	3.00e-30	126.00
IUUC-Vpa-130358	Vicugna pacos	98.02	0.00e+00	681.00
IUUC-Vvi-131406	Vitis vinifera	36.44	2.00e-55	209.00
IUUC-Xtr-132548	Xenopus tropicalis	85.01	0.00e+00	650.00
IUUC-Xma-133352	Xiphophorus maculatus	84.03	2.00e-176	611.00
IUUC-Yli-134466	Yarrowia lipolytica	31.22	3.00e-21	96.30
IUUC-Zma-135081	Zea mays	34.99	1.00e-50	193.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence