iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055527

Ensembl Protein ID

ENSMMUP00000007041.2

UniProt Accession

F7GJG7; F7GJG7_MACMU

Genbank Protein ID

AFH30864.1; EHH25373.1

Protein Name

GRB2-related adapter protein

Genbank Nucleotide ID

JSUE03016214; JH290358

Gene Name

GRAP; EGK_21404

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005327.3	ENSMMUT00000007495.3	ENSMMUP00000007041.2
ENSMMUG00000005327.3	ENSMMUT00000071268.1	ENSMMUP00000050024.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-28	99.7	4	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +ly+++a+++deL ++kGd+++++ + e d++W k+  el+g +G++P+n+++
   Q: 4    VALYSFQATESDELAFNKGDTLKIL-NMEDDQNWYKA--ELRGVEGFIPKNYIH 54
           58***********************.99*******99..9************96 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MESVALYSFQ ATESDELAFN KGDTLKILNM EDDQNWYKAE LRGVEGFIPK NYIHVKPHPW 60
YSGRISRQLA EEILMKRNHL GAFLIRESES SPGEFSVSVN YGDQVQHFKV LREASGKYFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCATCACAA GAAGCACCAG GGTTTAGGAA AAGATGGAGG GTCATTGGCA AATTGGTGAA 60
GGGGGGCCAG CATCTGGTGC CATGAGATTC AGTGCCTGAG CCAGCAGGAC AGCTTCGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

mcc:702473

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001277	Ailuropoda melanoleuca	94.47	3.00e-121	426.00
IUUC-Apl-003499	Anas platyrhynchos	64.84	8.00e-76	276.00
IUUC-Aca-004922	Anolis carolinensis	66.82	3.00e-86	310.00
IUUC-Ago-007965	Ashbya gossypii	48.15	1.00e-12	67.00
IUUC-Bta-012909	Bos taurus	90.32	2.00e-116	410.00
IUUC-Cja-018796	Callithrix jacchus	97.24	1.00e-125	441.00
IUUC-Cfa-021023	Canis familiaris	92.17	2.00e-118	418.00
IUUC-Cpo-021502	Cavia porcellus	95.39	2.00e-123	434.00
IUUC-Csa-024099	Chlorocebus sabaeus	98.62	2.00e-126	444.00
IUUC-Dno-029057	Dasypus novemcinctus	88.62	2.00e-85	307.00
IUUC-Eca-033722	Equus caballus	80.00	2.00e-100	358.00
IUUC-Eeu-035125	Erinaceus europaeus	78.63	5.00e-44	169.00
IUUC-Fca-036087	Felis catus	94.47	2.00e-121	427.00
IUUC-Fal-037633	Ficedula albicollis	77.67	2.00e-96	344.00
IUUC-Gga-041204	Gallus gallus	76.96	3.00e-97	347.00
IUUC-Ggo-044579	Gorilla gorilla	99.08	1.00e-127	448.00
IUUC-Hsa-045927	Homo sapiens	99.08	1.00e-127	448.00
IUUC-Loc-052457	Lepisosteus oculatus	61.11	1.00e-75	275.00
IUUC-Laf-053794	Loxodonta africana	94.01	6.00e-121	426.00
IUUC-Meu-056608	Macropus eugenii	83.25	1.00e-86	311.00
IUUC-Mmr-060743	Microcebus murinus	84.79	8.00e-105	372.00
IUUC-Mdo-063025	Monodelphis domestica	85.71	1.00e-111	395.00
IUUC-Mmu-064395	Mus musculus	91.71	3.00e-118	417.00
IUUC-Mpu-066088	Mustela putorius furo	92.63	6.00e-119	420.00
IUUC-Mlu-067003	Myotis lucifugus	92.63	3.00e-118	417.00
IUUC-Opr-071051	Ochotona princeps	69.12	2.00e-81	294.00
IUUC-Ont-071576	Oreochromis niloticus	61.57	1.00e-78	285.00
IUUC-Oan-073107	Ornithorhynchus anatinus	68.00	5.00e-84	303.00
IUUC-Ocu-074963	Oryctolagus cuniculus	93.12	1.00e-110	392.00
IUUC-Ola-086725	Oryzias latipes	58.04	1.00e-71	262.00
IUUC-Oga-088158	Otolemur garnettii	93.09	2.00e-120	424.00
IUUC-Oar-090223	Ovis aries	87.56	7.00e-112	396.00
IUUC-Pan-092422	Papio anubis	99.54	4.00e-128	449.00
IUUC-Psi-093655	Pelodiscus sinensis	80.09	1.00e-103	368.00
IUUC-Pca-100573	Procavia capensis	92.27	3.00e-98	350.00
IUUC-Pva-102471	Pteropus vampyrus	95.29	8.00e-108	382.00
IUUC-Rno-105932	Rattus norvegicus	90.32	5.00e-117	413.00
IUUC-Sha-107209	Sarcophilus harrisii	84.79	7.00e-102	362.00
IUUC-Tru-118065	Takifugu rubripes	59.26	3.00e-74	270.00
IUUC-Tni-120563	Tetraodon nigroviridis	56.02	3.00e-68	251.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence