iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-43	143.4	573	612
UBD/Beta-Prp	4.90e-81	270.6	532	713

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gHt+ v  ++f +  + l+s++ Dg ik+WD ++g +lk+
   Q: 573  GHTNAVQRCSFiNKqKQLISCGADGLIKIWDCSSGECLKT 612
           89**********77799********************986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           hk  + +v f + ++llat+s d+t+k+w+++t +++++l+gh+++v+ ++f++++k l++++ D++ik+wd s+g+c+ tl gh++++++ls + +gd +
   Q: 532  HKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMI 632
           666666799999***************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..............kt 168
           vs+++d + + w+  t+q++ee        ++++++  + + + + ++  l + +lD  +rl+++              + 
   Q: 633  VSADADGVFQFWKDCTEQEIEEeqekaklqVEQEQSLQNYMSKGDWTNAFLLAMTLDHPMRLFNVlkralgesrsrqdtEE 713
           *********************99****998777777778888889999999999*********994443333333333333 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA.

Protein Sequence
(Fasta)

MDLKTSYKGI SLNPIYAGSS AVATVSENGK ILATPVLDEI NIIDLTPGSR KILHKISNED 60
EQEITALKLT PDGQYLTYVS QAQLLKIFHL KTGKVVRSMK ISSPSYILDA DSTSTLLAVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCTGA AAACCTCATA TAAAGGTATA TCGTTAAACC CTATTTATGC AGGAAGCAGT 60
GCTGTTGCCA CTGTTTCAGA AAATGGTAAA ATACTAGCTA CTCCGGTGCT TGACGAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR013934--SSU_processome_Utp13
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08625--Utp13
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0031167--P:rRNA methylation

KEGG

sce:YLR222C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000765	Aegilops tauschii	27.67	4.00e-85	307.00
IUUC-Aml-002376	Ailuropoda melanoleuca	29.88	2.00e-104	371.00
IUUC-Atr-002486	Amborella trichopoda	29.82	6.00e-98	350.00
IUUC-Apl-003519	Anas platyrhynchos	30.41	7.00e-86	309.00
IUUC-Aca-004363	Anolis carolinensis	28.41	1.00e-41	161.00
IUUC-Aly-006152	Arabidopsis lyrata	29.95	2.00e-100	358.00
IUUC-Ath-006966	Arabidopsis thaliana	29.72	4.00e-99	353.00
IUUC-Ago-007746	Ashbya gossypii	63.66	0.00e+00	1098.00
IUUC-Acl-008009	Aspergillus clavatus	31.84	7.00e-120	423.00
IUUC-Afl-008681	Aspergillus flavus	30.71	7.00e-102	363.00
IUUC-Afu-008798	Aspergillus fumigatus	31.26	3.00e-110	391.00
IUUC-Ani-009278	Aspergillus nidulans	30.94	1.00e-114	405.00
IUUC-Ang-009640	Aspergillus niger	33.11	1.00e-120	425.00
IUUC-Aor-010160	Aspergillus oryzae	30.61	9.00e-102	362.00
IUUC-Ate-010320	Aspergillus terreus	31.01	4.00e-116	410.00
IUUC-Bgr-012054	Blumeria graminis	31.17	2.00e-111	394.00
IUUC-Bta-012611	Bos taurus	30.56	1.00e-97	348.00
IUUC-Bci-013797	Botrytis cinerea	33.63	2.00e-126	444.00
IUUC-Bdi-014384	Brachypodium distachyon	29.81	1.00e-101	362.00
IUUC-Bol-015097	Brassica oleracea	30.27	9.00e-94	336.00
IUUC-Bra-017798	Brassica rapa	30.27	2.00e-94	338.00
IUUC-Cel-018664	Caenorhabditis elegans	25.93	2.00e-75	275.00
IUUC-Cja-019092	Callithrix jacchus	29.69	9.00e-104	369.00
IUUC-Cfa-021040	Canis familiaris	30.23	4.00e-102	363.00
IUUC-Cpo-022529	Cavia porcellus	31.00	8.00e-99	352.00
IUUC-Cre-022986	Chlamydomonas reinhardtii	47.41	1.00e-36	142.00
IUUC-Csa-024205	Chlorocebus sabaeus	30.18	2.00e-101	361.00
IUUC-Cin-025560	Ciona intestinalis	28.93	1.00e-91	328.00
IUUC-Cgl-026481	Colletotrichum gloeosporioides	34.64	7.00e-140	489.00
IUUC-Cne-027082	Cryptococcus neoformans	29.69	3.00e-91	327.00
IUUC-Cme-027159	Cyanidioschyzon merolae	21.30	7.00e-26	111.00
IUUC-Dre-028138	Danio rerio	31.13	1.00e-85	309.00
IUUC-Dno-029914	Dasypus novemcinctus	26.63	4.00e-53	201.00
IUUC-Dor-030685	Dipodomys ordii	29.62	3.00e-61	228.00
IUUC-Dse-031429	Dothistroma septosporum	32.15	3.00e-123	434.00
IUUC-Dme-031995	Drosophila melanogaster	24.77	1.00e-63	236.00
IUUC-Ete-033086	Echinops telfairi	33.49	9.00e-69	253.00
IUUC-Eca-034354	Equus caballus	30.80	9.00e-98	349.00
IUUC-Eeu-034832	Erinaceus europaeus	32.48	8.00e-68	249.00
IUUC-Fca-036136	Felis catus	30.47	5.00e-102	363.00
IUUC-Fal-036859	Ficedula albicollis	30.59	1.00e-102	365.00
IUUC-Fox-037863	Fusarium oxysporum	33.75	4.00e-121	426.00
IUUC-Fso-038389	Fusarium solani	33.41	2.00e-130	458.00
IUUC-Gmo-038711	Gadus morhua	26.98	6.00e-79	286.00
IUUC-Ggr-039820	Gaeumannomyces graminis	32.51	2.00e-123	434.00
IUUC-Gga-040263	Gallus gallus	32.07	4.00e-105	373.00
IUUC-Gac-041291	Gasterosteus aculeatus	29.87	6.00e-102	363.00
IUUC-Gma-044328	Glycine max	31.07	2.00e-107	382.00
IUUC-Ggo-044693	Gorilla gorilla	30.18	1.00e-101	362.00
IUUC-Hsa-046048	Homo sapiens	30.18	9.00e-102	362.00
IUUC-Hvu-047608	Hordeum vulgare	29.27	3.00e-102	364.00
IUUC-Itr-048391	Ictidomys tridecemlineatus	30.13	9.00e-106	375.00
IUUC-Kpa-049209	Komagataella pastoris	51.21	0.00e+00	786.00
IUUC-Lch-050085	Latimeria chalumnae	29.48	2.00e-95	341.00
IUUC-Lpe-050945	Leersia perrieri	30.64	2.00e-100	358.00
IUUC-Loc-052679	Lepisosteus oculatus	31.47	8.00e-117	412.00
IUUC-Laf-053685	Loxodonta africana	29.68	7.00e-92	329.00
IUUC-Mcc-055861	Macaca mulatta	30.31	1.00e-101	362.00
IUUC-Meu-056820	Macropus eugenii	28.26	9.00e-70	256.00
IUUC-Mor-057234	Magnaporthe oryzae	32.93	5.00e-122	429.00
IUUC-Mpo-057456	Magnaporthe poae	33.14	1.00e-93	335.00
IUUC-Mtr-058122	Medicago truncatula	31.30	1.00e-107	382.00
IUUC-Mla-058980	Melampsora laricipopulina	28.64	3.00e-76	277.00
IUUC-Mga-060080	Meleagris gallopavo	31.91	4.00e-103	367.00
IUUC-Mvi-060338	Microbotryum violaceum	31.28	1.00e-111	395.00
IUUC-Mmr-060762	Microcebus murinus	30.34	1.00e-98	352.00
IUUC-Mdo-061975	Monodelphis domestica	30.55	1.00e-94	339.00
IUUC-Mmu-064038	Mus musculus	31.04	1.00e-101	362.00
IUUC-Mac-065189	Musa acuminata	29.66	1.00e-106	379.00
IUUC-Mpu-066526	Mustela putorius furo	30.14	3.00e-100	357.00
IUUC-Mlu-067716	Myotis lucifugus	30.38	7.00e-109	386.00
IUUC-Nfi-068474	Neosartorya fischeri	31.61	3.00e-112	397.00
IUUC-Ncr-068826	Neurospora crassa	31.44	6.00e-117	413.00
IUUC-Nle-069832	Nomascus leucogenys	30.06	2.00e-103	368.00
IUUC-Opr-071183	Ochotona princeps	29.99	3.00e-100	357.00
IUUC-Ont-072371	Oreochromis niloticus	29.50	4.00e-97	347.00
IUUC-Oan-073491	Ornithorhynchus anatinus	26.66	1.00e-70	259.00
IUUC-Oba-075963	Oryza barthii	30.47	8.00e-102	362.00
IUUC-Obr-076173	Oryza brachyantha	30.84	1.00e-101	362.00
IUUC-Ogl-077692	Oryza glaberrima	30.26	3.00e-101	360.00
IUUC-Ogu-078965	Oryza glumaepatula	30.47	8.00e-102	362.00
IUUC-Oin-079708	Oryza indica	30.34	2.00e-101	361.00
IUUC-Olo-080679	Oryza longistaminata	30.26	8.00e-100	356.00
IUUC-Oni-082960	Oryza nivara	30.34	2.00e-101	361.00
IUUC-Opu-083282	Oryza punctata	31.13	2.00e-101	362.00
IUUC-Oru-085224	Oryza rufipogon	30.47	4.00e-102	363.00
IUUC-Osa-085320	Oryza sativa	30.47	4.00e-102	363.00
IUUC-Ola-086370	Oryzias latipes	33.88	5.00e-34	137.00
IUUC-Olu-087814	Ostreococcus lucimarinus	28.45	4.00e-80	290.00
IUUC-Oga-088458	Otolemur garnettii	30.06	1.00e-108	385.00
IUUC-Oar-090032	Ovis aries	28.12	3.00e-66	244.00
IUUC-Ptr-090749	Pan troglodytes	30.05	2.00e-102	364.00
IUUC-Pan-091691	Papio anubis	29.57	2.00e-93	335.00
IUUC-Psi-093200	Pelodiscus sinensis	31.02	8.00e-104	369.00
IUUC-Pma-094165	Petromyzon marinus	27.94	4.00e-54	204.00
IUUC-Pno-095048	Phaeosphaeria nodorum	33.20	4.00e-100	357.00
IUUC-Ppa-095336	Physcomitrella patens	30.63	2.00e-110	391.00
IUUC-Pfo-096132	Poecilia formosa	28.20	6.00e-91	327.00
IUUC-Pab-097855	Pongo abelii	30.06	2.00e-102	364.00
IUUC-Pop-099434	Populus trichocarpa	28.59	3.00e-97	347.00
IUUC-Pca-100232	Procavia capensis	36.73	1.00e-38	153.00
IUUC-Ppe-101665	Prunus persica	28.72	3.00e-101	361.00
IUUC-Pva-102178	Pteropus vampyrus	31.04	1.00e-101	362.00
IUUC-Pgr-103288	Puccinia graminis	25.86	1.00e-62	233.00
IUUC-Ptt-103808	Puccinia triticina	27.68	3.00e-65	241.00
IUUC-Pte-104205	Pyrenophora teres	33.85	1.00e-121	429.00
IUUC-Pyt-104658	Pyrenophora triticirepentis	32.48	3.00e-113	400.00
IUUC-Rno-105617	Rattus norvegicus	31.04	5.00e-100	357.00
IUUC-Sha-107378	Sarcophilus harrisii	30.64	1.00e-95	342.00
IUUC-Sja-107718	Schizosaccharomyces japonicus	36.32	7.00e-139	485.00
IUUC-Spo-108361	Schizosaccharomyces pombe	35.70	3.00e-130	457.00
IUUC-Ssl-108592	Sclerotinia sclerotiorum	33.48	5.00e-132	463.00
IUUC-Smo-109632	Selaginella moellendorffii	31.38	9.00e-110	389.00
IUUC-Sit-110258	Setaria italica	31.39	9.00e-106	375.00
IUUC-Sly-111521	Solanum lycopersicum	29.59	2.00e-100	358.00
IUUC-Sbi-114768	Sorghum bicolor	30.67	4.00e-104	370.00
IUUC-Sre-115159	Sporisorium reilianum	27.94	3.00e-80	291.00
IUUC-Ssc-116342	Sus scrofa	23.96	6.00e-42	163.00
IUUC-Tgu-117320	Taeniopygia guttata	30.28	3.00e-98	350.00
IUUC-Tru-118024	Takifugu rubripes	29.80	1.00e-96	345.00
IUUC-Tni-119971	Tetraodon nigroviridis	29.21	1.00e-94	338.00
IUUC-Tca-121248	Theobroma cacao	32.30	2.00e-106	378.00
IUUC-Tre-122079	Trichoderma reesei	33.19	2.00e-120	424.00
IUUC-Tvi-122554	Trichoderma virens	33.19	2.00e-121	428.00
IUUC-Tae-123690	Triticum aestivum	30.46	1.00e-102	365.00
IUUC-Tur-126436	Triticum urartu	29.26	5.00e-83	300.00
IUUC-Tme-126942	Tuber melanosporum	34.28	2.00e-122	431.00
IUUC-Ttr-128964	Tursiops truncatus	29.44	6.00e-103	366.00
IUUC-Uma-129473	Ustilago maydis	29.01	1.00e-85	309.00
IUUC-Vda-129749	Verticillium dahliae	33.90	6.00e-125	439.00
IUUC-Vvi-131511	Vitis vinifera	30.21	7.00e-105	373.00
IUUC-Xtr-132816	Xenopus tropicalis	27.27	1.00e-71	262.00
IUUC-Xma-133672	Xiphophorus maculatus	28.69	6.00e-94	336.00
IUUC-Yli-134602	Yarrowia lipolytica	40.32	2.00e-169	587.00
IUUC-Zma-135559	Zea mays	30.42	1.00e-101	362.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence