iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000139218.17	ENST00000369367.7	ENSP00000358374.3
ENSG00000139218.17	ENST00000550893.2	ENSP00000477742.1
ENSG00000139218.17	ENST00000547018.5	ENSP00000446746.1
ENSG00000139218.17	ENST00000551391.1	ENSP00000478596.1
ENSG00000139218.17	ENST00000266589.10	ENSP00000266589.6
ENSG00000139218.17	ENST00000395454.6	ENSP00000378840.2
ENSG00000139218.17	ENST00000395453.2	ENSP00000378839.1

Annotation

Cancer Mutation
ICGC	COSMIC	CGAP	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
THPA	HPM
DNA & RNA Element
AREsite	circBase	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	miRNAMap
SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
GWASdb	OMIM
Post-translational Modifications (PTMs)
CPLM	BioGRID
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-06	30.2	57	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ +  k+  +  +C+Hvf+ +C+ kw      + + ++CP++r
   Q: 57   CPICLNCLleKEVGFPESCNHVFCMTCILKW------AETLASCPIDR 98
           ******776444344467*************......********986 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MIVSIFSNKE TLFQREMKKK TVCTLNMGDK KYEDMEGEEN GDNTISTGLL YSEADRCPIC 60
LNCLLEKEVG FPESCNHVFC MTCILKWAET LASCPIDRKP FQAVFKFSAL EGYVKVQ 117

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGTGCCA GAAAAGCGAC GTCCTCAGGG CGGGAGCAGG GGACGCCGCA ACGTAGTCTG 60
CGAGAATGCA GGAAGGCGGC AGTGAAGCGG TCGGTCGGCG GGGCCGCGGC AAAGTGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002853	Amborella trichopoda	38.33	2.00e-07	49.30
IUUC-Aly-006143	Arabidopsis lyrata	36.07	1.00e-06	46.60
IUUC-Ath-007240	Arabidopsis thaliana	36.07	2.00e-06	46.20
IUUC-Bol-015219	Brassica oleracea	32.18	5.00e-07	48.10
IUUC-Cpo-021419	Cavia porcellus	84.26	3.00e-50	194.00
IUUC-Csa-023947	Chlorocebus sabaeus	96.04	9.00e-57	216.00
IUUC-Cho-024396	Choloepus hoffmanni	86.00	1.00e-46	182.00
IUUC-Dno-029714	Dasypus novemcinctus	78.85	2.00e-42	168.00
IUUC-Lpe-050939	Leersia perrieri	34.48	2.00e-06	46.20
IUUC-Mlu-067644	Myotis lucifugus	86.14	3.00e-49	191.00
IUUC-Oan-073333	Ornithorhynchus anatinus	59.41	6.00e-33	133.00
IUUC-Oba-075008	Oryza barthii	32.14	4.00e-05	42.00
IUUC-Obr-076867	Oryza brachyantha	34.48	5.00e-06	45.10
IUUC-Ogl-077681	Oryza glaberrima	33.93	9.00e-06	44.30
IUUC-Ogu-078356	Oryza glumaepatula	33.93	9.00e-06	44.30
IUUC-Oin-079949	Oryza indica	33.93	9.00e-06	44.30
IUUC-Ome-081618	Oryza meridionalis	33.93	9.00e-06	43.90
IUUC-Oni-082491	Oryza nivara	33.93	9.00e-06	44.30
IUUC-Opu-083979	Oryza punctata	33.93	1.00e-05	43.50
IUUC-Osa-085324	Oryza sativa	33.93	9.00e-06	44.30
IUUC-Sit-110148	Setaria italica	34.48	6.00e-06	44.70
IUUC-Sly-111635	Solanum lycopersicum	34.43	7.00e-08	50.80
IUUC-Stu-111988	Solanum tuberosum	34.43	1.00e-07	50.10
IUUC-Sbi-114796	Sorghum bicolor	33.93	3.00e-05	42.40
IUUC-Tca-121633	Theobroma cacao	28.70	1.00e-07	50.10
IUUC-Vvi-130847	Vitis vinifera	32.31	7.00e-07	47.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence