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Tag Content
UUCD2 ID IUUC-Dre-028343
UUCD1 version UUC-DaR-00290
Ensembl Protein ID ENSDARP00000103408.3
UniProt Accession F1Q745; F1Q745_DANRE
Genbank Protein ID ENSDARP00000103408
Protein Name Ubiquitin protein ligase E3 component n-recognin 2
Genbank Nucleotide ID AL935294
Gene Name ubr2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000070164.5 ENSDART00000114040.3 ENSDARP00000103408.3
ENSDARG00000070164.5 ENSDART00000102748.5 ENSDARP00000093524.5
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 6.90e-09 37.0 1116 1221
E3 activity/N-recognin/N-domain 9.20e-37 126.0 231 306
E3 activity/N-recognin/UBR-box 8.90e-30 103.9 102 172
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf......kd......................................gplvlpCgHvfhadClqkw.............. 29
           C++C+e+       k                                       g+++++CgH++h +C+q++              
   Q: 1116 CILCQEEQeirsdgKAmvlaafvqrstvmsknrkrpphnpdkydplfmhpdlsfGTHTGSCGHIMHSHCWQRYfeavqakeqrrqqr 1202
           8899776655544400334444444444444445555555555555555555556899***************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + +++++++ef+CPlC
   Q: 1203 lrvHTSYDVENGEFLCPLC 1221
           ******************* PP
   

   E3 activity/N-recognin/N-domain
   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea  fat++d++GR++v++Gd++ ce+ak++i++n++++++ pL+V+v
   Q: 231  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAVSFATTVDRDGRKSVRFGDFQFCEQAKSVIVRNTSRQTK-PLRVQV 306
           9*********************************************************************.****98 PP
   

   E3 activity/N-recognin/UBR-box
   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfkvge +y+Cr+C+ d+t+vlC++Cf  +vHk+H+y++++sggggfCdCGdteAw++g++C+k++
   Q: 102  QLCGHVFKVGEPTYSCRECAADPTCVLCMQCFLGSVHKEHRYRMTTSGGGGFCDCGDTEAWKKGPYCQKHE 172
           68*******************************************************************96 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
EVKMAAAETD RDAPSALCSE FLNFSAKDTA AKWLQVSNLP KEVYQHLACY VPKIYCLGPN 60
LNPQNEDLLA QLLLQGPLEW YLCGEEPSVG LSKLEQNNQP SQLCGHVFKV GEPTYSCREC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028343|E3,RING;E3,N-domain;E3,UBR-box|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGTAAAGA TGGCGGCGGC CGAGACCGAT CGTGATGCAC CGTCCGCTCT GTGTAGCGAA 60
TTCCTCAATT TCTCCGCTAA GGACACCGCT GCGGTAGGCG ACAGTTTTAT GAACACTACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028343|E3,RING;E3,N-domain;E3,UBR-box|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR
PROSITE

PS51157--ZF_UBR
Pfam

PF02617--ClpS
PF02207--zf-UBR
SMART

SM00396--ZnF_UBR1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000949 Aegilops tauschii 26.94 6.00e-23 104.00
IUUC-Aml-001876 Ailuropoda melanoleuca 66.85 0.00e+00 2108.00
IUUC-Atr-002501 Amborella trichopoda 31.35 6.00e-31 131.00
IUUC-Apl-003828 Anas platyrhynchos 74.67 0.00e+00 2553.00
IUUC-Aca-005189 Anolis carolinensis 72.91 0.00e+00 2556.00
IUUC-Aly-005901 Arabidopsis lyrata 28.66 7.00e-30 127.00
IUUC-Ath-007148 Arabidopsis thaliana 28.06 2.00e-28 122.00
IUUC-Ago-007946 Ashbya gossypii 23.27 1.00e-32 136.00
IUUC-Acl-008055 Aspergillus clavatus 25.08 6.00e-39 157.00
IUUC-Afl-008479 Aspergillus flavus 24.05 7.00e-51 197.00
IUUC-Afu-008929 Aspergillus fumigatus 23.45 2.00e-56 216.00
IUUC-Ani-009334 Aspergillus nidulans 24.01 1.00e-51 199.00
IUUC-Ang-009550 Aspergillus niger 23.78 2.00e-50 195.00
IUUC-Aor-010124 Aspergillus oryzae 24.02 5.00e-51 197.00
IUUC-Ate-010550 Aspergillus terreus 23.76 2.00e-51 199.00
IUUC-Ame-011917 Astyanax mexicanus 88.62 0.00e+00 3006.00
IUUC-Bgr-011999 Blumeria graminis 21.96 6.00e-44 174.00
IUUC-Bta-012768 Bos taurus 72.53 0.00e+00 2516.00
IUUC-Bci-013834 Botrytis cinerea 22.73 1.00e-46 183.00
IUUC-Bdi-014635 Brachypodium distachyon 25.29 8.00e-31 130.00
IUUC-Bol-015669 Brassica oleracea 29.59 6.00e-32 134.00
IUUC-Bra-017776 Brassica rapa 29.29 6.00e-32 134.00
IUUC-Cel-018476 Caenorhabditis elegans 32.16 1.00e-84 309.00
IUUC-Cja-019797 Callithrix jacchus 71.72 0.00e+00 1957.00
IUUC-Cfa-020950 Canis familiaris 72.87 0.00e+00 2515.00
IUUC-Cpo-022385 Cavia porcellus 72.36 0.00e+00 2513.00
IUUC-Csa-024082 Chlorocebus sabaeus 72.42 0.00e+00 2520.00
IUUC-Cho-025029 Choloepus hoffmanni 74.21 0.00e+00 1226.00
IUUC-Cin-025148 Ciona intestinalis 34.54 2.00e-136 480.00
IUUC-Csv-026296 Ciona savignyi 30.86 7.00e-19 88.20
IUUC-Cgl-026605 Colletotrichum gloeosporioides 24.96 1.00e-49 192.00
IUUC-Cne-026823 Cryptococcus neoformans 22.95 2.00e-45 179.00
IUUC-Dno-029427 Dasypus novemcinctus 45.45 0.00e+00 1507.00
IUUC-Dor-030207 Dipodomys ordii 63.38 0.00e+00 1251.00
IUUC-Dse-031531 Dothistroma septosporum 25.17 4.00e-59 224.00
IUUC-Dme-031910 Drosophila melanogaster 34.73 0.00e+00 702.00
IUUC-Ete-033162 Echinops telfairi 71.00 0.00e+00 1155.00
IUUC-Eca-033454 Equus caballus 71.92 0.00e+00 2487.00
IUUC-Eeu-034783 Erinaceus europaeus 59.96 0.00e+00 1140.00
IUUC-Fca-036588 Felis catus 72.68 0.00e+00 2513.00
IUUC-Fal-036919 Ficedula albicollis 73.25 0.00e+00 2487.00
IUUC-Fox-037984 Fusarium oxysporum 26.08 2.00e-45 179.00
IUUC-Fso-038463 Fusarium solani 24.75 1.00e-46 183.00
IUUC-Gmo-039698 Gadus morhua 77.20 0.00e+00 1791.00
IUUC-Ggr-040070 Gaeumannomyces graminis 23.31 1.00e-46 183.00
IUUC-Gga-041123 Gallus gallus 74.15 0.00e+00 2578.00
IUUC-Gac-042622 Gasterosteus aculeatus 73.33 0.00e+00 2438.00
IUUC-Gma-043622 Glycine max 28.99 1.00e-29 127.00
IUUC-Ggo-045583 Gorilla gorilla 71.49 0.00e+00 2499.00
IUUC-Hsa-046343 Homo sapiens 72.99 0.00e+00 2535.00
IUUC-Hvu-047707 Hordeum vulgare 29.11 4.00e-23 104.00
IUUC-Itr-048410 Ictidomys tridecemlineatus 46.61 0.00e+00 1513.00
IUUC-Kpa-049088 Komagataella pastoris 23.30 5.00e-45 177.00
IUUC-Lch-049649 Latimeria chalumnae 70.08 0.00e+00 2378.00
IUUC-Lpe-051516 Leersia perrieri 25.35 9.00e-32 134.00
IUUC-Loc-052818 Lepisosteus oculatus 79.23 0.00e+00 2783.00
IUUC-Lma-053059 Leptosphaeria maculans 23.48 5.00e-53 204.00
IUUC-Laf-054142 Loxodonta africana 72.90 0.00e+00 2515.00
IUUC-Mcc-055677 Macaca mulatta 72.24 0.00e+00 2509.00
IUUC-Meu-056204 Macropus eugenii 52.83 3.00e-157 550.00
IUUC-Mor-057051 Magnaporthe oryzae 22.42 3.00e-51 198.00
IUUC-Mpo-057372 Magnaporthe poae 24.80 7.00e-48 187.00
IUUC-Mtr-058538 Medicago truncatula 30.06 8.00e-31 130.00
IUUC-Mla-058963 Melampsora laricipopulina 25.25 4.00e-57 218.00
IUUC-Mga-059698 Meleagris gallopavo 74.70 0.00e+00 2575.00
IUUC-Mvi-060535 Microbotryum violaceum 25.73 2.00e-49 192.00
IUUC-Mmr-060901 Microcebus murinus 71.05 0.00e+00 2459.00
IUUC-Mdo-062014 Monodelphis domestica 73.60 0.00e+00 2565.00
IUUC-Mmu-063699 Mus musculus 72.13 0.00e+00 2504.00
IUUC-Mac-064773 Musa acuminata 30.36 1.00e-29 126.00
IUUC-Mpu-066153 Mustela putorius furo 72.64 0.00e+00 2513.00
IUUC-Mlu-068151 Myotis lucifugus 71.62 0.00e+00 2471.00
IUUC-Nfi-068403 Neosartorya fischeri 23.40 6.00e-56 214.00
IUUC-Ncr-068864 Neurospora crassa 22.93 3.00e-43 172.00
IUUC-Nle-069529 Nomascus leucogenys 72.53 0.00e+00 2523.00
IUUC-Opr-071107 Ochotona princeps 64.49 0.00e+00 969.00
IUUC-Ont-072189 Oreochromis niloticus 74.08 0.00e+00 2402.00
IUUC-Oan-072893 Ornithorhynchus anatinus 74.53 0.00e+00 2580.00
IUUC-Ocu-074082 Oryctolagus cuniculus 72.71 0.00e+00 2497.00
IUUC-Oba-075295 Oryza barthii 25.27 2.00e-24 109.00
IUUC-Ogl-077571 Oryza glaberrima 25.79 2.00e-31 132.00
IUUC-Ogu-078497 Oryza glumaepatula 25.16 1.00e-24 109.00
IUUC-Oin-079343 Oryza indica 25.12 3.00e-23 105.00
IUUC-Olo-081056 Oryza longistaminata 25.27 1.00e-24 109.00
IUUC-Ome-081738 Oryza meridionalis 24.13 8.00e-16 80.90
IUUC-Oni-083099 Oryza nivara 25.12 1.00e-23 106.00
IUUC-Opu-083202 Oryza punctata 29.79 3.00e-28 122.00
IUUC-Oru-084471 Oryza rufipogon 25.39 5.00e-24 108.00
IUUC-Osa-085336 Oryza sativa 27.32 2.00e-23 105.00
IUUC-Ola-087460 Oryzias latipes 70.64 0.00e+00 2353.00
IUUC-Olu-087832 Ostreococcus lucimarinus 24.59 1.30e-01 32.30
IUUC-Oga-088432 Otolemur garnettii 72.70 0.00e+00 2537.00
IUUC-Oar-090206 Ovis aries 71.52 0.00e+00 2494.00
IUUC-Ptr-091180 Pan troglodytes 71.73 0.00e+00 2502.00
IUUC-Pan-092375 Papio anubis 72.30 0.00e+00 2516.00
IUUC-Psi-093049 Pelodiscus sinensis 74.37 0.00e+00 2556.00
IUUC-Pma-094152 Petromyzon marinus 47.27 0.00e+00 630.00
IUUC-Pno-094877 Phaeosphaeria nodorum 21.87 1.00e-41 166.00
IUUC-Ppa-095715 Physcomitrella patens 30.56 2.00e-26 116.00
IUUC-Pfo-096524 Poecilia formosa 70.89 0.00e+00 2272.00
IUUC-Pab-097989 Pongo abelii 71.14 0.00e+00 2451.00
IUUC-Pca-100207 Procavia capensis 69.27 0.00e+00 982.00
IUUC-Ppe-101802 Prunus persica 30.80 6.00e-29 124.00
IUUC-Pva-102724 Pteropus vampyrus 46.86 0.00e+00 1092.00
IUUC-Pgr-103372 Puccinia graminis 23.88 3.00e-51 198.00
IUUC-Ptt-103878 Puccinia triticina 24.10 3.00e-49 192.00
IUUC-Pte-104174 Pyrenophora teres 22.95 1.00e-52 202.00
IUUC-Pyt-104431 Pyrenophora triticirepentis 22.91 1.00e-52 202.00
IUUC-Rno-105567 Rattus norvegicus 71.23 0.00e+00 2438.00
IUUC-Sce-106272 Saccharomyces cerevisiae 21.24 2.00e-27 119.00
IUUC-Sha-106980 Sarcophilus harrisii 74.20 0.00e+00 2499.00
IUUC-Sja-107980 Schizosaccharomyces japonicus 23.69 7.00e-48 187.00
IUUC-Spo-108183 Schizosaccharomyces pombe 25.53 2.00e-54 208.00
IUUC-Smo-108719 Selaginella moellendorffii 33.33 4.00e-30 128.00
IUUC-Sit-110716 Setaria italica 25.19 4.00e-31 131.00
IUUC-Sly-111286 Solanum lycopersicum 30.42 2.00e-31 132.00
IUUC-Sar-113332 Sorex araneus 67.51 0.00e+00 1682.00
IUUC-Sbi-114577 Sorghum bicolor 28.89 1.00e-30 129.00
IUUC-Sre-115045 Sporisorium reilianum 24.63 9.00e-48 187.00
IUUC-Ssc-115525 Sus scrofa 73.82 0.00e+00 1980.00
IUUC-Tgu-116943 Taeniopygia guttata 73.94 0.00e+00 2563.00
IUUC-Tru-117673 Takifugu rubripes 72.62 0.00e+00 2420.00
IUUC-Tsy-119032 Tarsius syrichta 73.93 0.00e+00 1481.00
IUUC-Tni-119987 Tetraodon nigroviridis 73.05 0.00e+00 2382.00
IUUC-Tca-121077 Theobroma cacao 27.84 3.00e-30 128.00
IUUC-Tre-122137 Trichoderma reesei 25.35 3.00e-65 245.00
IUUC-Tvi-122272 Trichoderma virens 24.17 1.00e-61 232.00
IUUC-Tae-125358 Triticum aestivum 29.11 1.00e-22 103.00
IUUC-Tur-126562 Triticum urartu 29.04 6.00e-27 117.00
IUUC-Tme-127156 Tuber melanosporum 22.36 4.00e-46 181.00
IUUC-Tbe-128103 Tupaia belangeri 65.47 0.00e+00 905.00
IUUC-Ttr-128253 Tursiops truncatus 75.15 0.00e+00 1696.00
IUUC-Uma-129344 Ustilago maydis 24.66 3.00e-51 198.00
IUUC-Vda-129778 Verticillium dahliae 26.31 2.00e-51 199.00
IUUC-Vpa-130540 Vicugna pacos 68.95 0.00e+00 2249.00
IUUC-Vvi-131290 Vitis vinifera 31.56 4.00e-30 127.00
IUUC-Xtr-132690 Xenopus tropicalis 72.51 0.00e+00 2513.00
IUUC-Xma-133748 Xiphophorus maculatus 71.15 0.00e+00 2202.00
IUUC-Yli-134662 Yarrowia lipolytica 24.42 2.00e-34 142.00
IUUC-Zma-135553 Zea mays 23.94 1.00e-16 84.00
Created Date 25-Jun-2017

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