iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	19196655

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.051	14.5	4	40

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 102  lldrlpeeilveilklldkeellraarvcrrwqelas 138
           ++++lp++++ eil ++++++l r++++c+ w++l +
   Q: 4    IQEQLPNDLVEEILCRVPATSLRRLRSTCKAWNRLFK 40
           6789*****************************8776 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Negative regulator of EIN2 protein stability.

Protein Sequence
(Fasta)

MKTIQEQLPN DLVEEILCRV PATSLRRLRS TCKAWNRLFK GDRILASKHF EKSAKQFRSL 60
SLRNDYRIFP ISFNLHGNSP SLELKSELID PHSKNSAAPF EISRVIHCEG LLLCSSQLDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAAATTCA ATGCTCAATA TGATCTCATG GGAACGAAAC AGGGGAAATT TGATTGCCAC 60
AAATATATGG GCTTTTAAAG TGGGCCTTGT TAGATTCTTA TCAGGTCCAT GTCACTCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006527--F-box-assoc_dom_typ1
IPR017451--F-box-assoc_interact_dom
IPR001810--F-box_dom
IPR011043--Gal_Oxase/kelch_b-propeller

PROSITE

PS50181--FBOX

Pfam

PF00646--F-box
PF07734--FBA_1

SMART

SM00256--FBOX

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

ath:AT3G18910

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000580	Aegilops tauschii	22.22	8.00e-04	37.70
IUUC-Atr-002546	Amborella trichopoda	25.93	1.00e-07	50.10
IUUC-Bta-012582	Bos taurus	22.37	3.30e-02	32.00
IUUC-Cfa-020892	Canis familiaris	29.35	1.20e-02	32.70
IUUC-Ete-033050	Echinops telfairi	37.50	1.30e-02	32.70
IUUC-Gga-040543	Gallus gallus	53.85	1.30e-01	31.20
IUUC-Itr-048148	Ictidomys tridecemlineatus	23.03	4.00e-03	35.00
IUUC-Mla-058968	Melampsora laricipopulina	26.00	8.90e-02	30.80
IUUC-Mmr-061649	Microcebus murinus	24.81	5.00e-03	34.30
IUUC-Mpu-066666	Mustela putorius furo	29.90	4.70e-02	32.70
IUUC-Ogu-078184	Oryza glumaepatula	24.21	3.00e-07	51.20
IUUC-Oar-089846	Ovis aries	30.00	8.00e-04	34.30
IUUC-Pno-094803	Phaeosphaeria nodorum	20.80	3.00e-03	35.40
IUUC-Pte-104263	Pyrenophora teres	24.46	3.00e-03	35.00
IUUC-Pyt-104608	Pyrenophora triticirepentis	24.31	2.00e-03	35.40
IUUC-Rno-105954	Rattus norvegicus	23.68	2.10e-02	32.30
IUUC-Ssc-115447	Sus scrofa	23.03	8.00e-03	33.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence