iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cme-027348

Ensembl Protein ID

CMR057CT

UniProt Accession

M1VAY1; M1VAY1_CYAM1

Genbank Protein ID

BAM82334.1

Protein Name

Ubiquitin-specific protease

Genbank Nucleotide ID

AP006500

Gene Name

CYME_CMR057C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CMR057C	CMR057CT	CMR057CT

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-57	192.9	54	642

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkk..................................av 68
           Gl+NlgNtC++NSvLQcL+ +p+l++++ + k++++ +      +g+++ +l+ ++  lw ++++                                    
   Q: 54   GLENLGNTCFFNSVLQCLARLPSLQSYFQSTKSNAIVR-----FEGAVTLALRLFLMTLWRHERQraqkrifadsstgtesdiaagssapnhtndsaalER 149
           9*****************************55555554.....4688888888888888844444466778888888888888888888888888888899 PP
   S: 69   sprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeed.kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sree 167
           ++r+l++ ++++ ++f+g +qqDa+E+l  ll ++++e ++       +++  +  s+++   + k+ ++ +s++ d+F+ ++++++ +++ + +  +r+e
   Q: 150  ATRRLFEEIGEKCPRFKGWAQQDAHELLLALLWTIDDEEQE-------RLRAGKsMSKTP--DSAKTVEQARSFVRDIFECRVEDRLEMPSSGGKPqVRHE 241
           9999***********************************44.......222222022233..3578999999*****************99987776**** PP
   S: 168  pfldlslpvpgkeetkke................................................................................... 185
           + l lslp+ + +++                                                                                      
   Q: 242  ECLALSLPILRLRQSGDArvrggrneeqragtrdmcasgcsvdgkdapkagadarrqnldgtdlsetewnqsrslmqannrsysededydesdcrlacvss 342
           *********97775544478999****************************************************************************** PP
   S: 186  ..............................................................slqdcLesftkeeelegenkyycekck............ 212
                                                                          l +c+++++++e +e  +  +++k +            
   Q: 343  lfddvelddepacrdsasracsatrasstgigvhggllaltcepmhsknsvhgssqmsevctRLGECIAEWARTEVIELVQSTQTSKECattghdaeknss 443
           ******************************************************************************98887766655588888888888 PP
   S: 213  .....................................................................kkqeaekklklkklPevLilhLkRfsfseeqk 244
                                                                                +  +a+k ++l++ P++L+lh+kRf+ + + +
   Q: 444  eklasnkeqstsctssalpdintangvrcesippgsqtgagavstsngfhsgdsaaaghasetvsdweaAPLKARKWMRLENAPRCLVLHMKRFT-QLDVG 543
           8888888888888888888888888888888888777777777777777777776666665555555544444*********************5.55567 PP
   S: 245  srekinkkvefpleLdlspfctspeekqke.....kkkYeLiavvvHsGslssGHYvayvkn.....ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
             +ki+++++fp++L+l +  +++  +  +     +++YeL++vv H G+l+ GHYvayv+      ++++W++++D ++++++ +evl+   ++aY+lfY
   Q: 544  YVTKIDDHISFPETLSLGELSETEALAPMVaadlaRVRYELCGVVEHNGTLHFGHYVAYVRArrvatSNQQWFYCSDRHIRSCTLDEVLQ---AQAYLLFY 641
           778***************88877444433366777***************************888877888*******************...******** PP
   S: 336  k 336
            
   Q: 642  F 642
           6 PP

Organism

Cyanidioschyzon merolae

Protein Sequence
(Fasta)

MSRGRPRRGG KKGHARKKAR AENRHGRGTV CETPPSPAAE PPSDSEQELC IPAGLENLGN 60
TCFFNSVLQC LARLPSLQSY FQSTKSNAIV RFEGAVTLAL RLFLMTLWRH ERQRAQKRIF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGCGGG GCAGGCCTCG GCGTGGTGGA AAAAAGGGGC ACGCGCGGAA GAAAGCACGC 60
GCTGAAAACC GGCACGGTAG GGGCACGGTT TGTGAAACGC CTCCTTCACC GGCGGCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cme:CYME_CMR057C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	36.76	1.00e-18	86.30
IUUC-Aml-001931	Ailuropoda melanoleuca	39.19	4.00e-23	100.00
IUUC-Atr-003015	Amborella trichopoda	37.01	1.00e-19	89.70
IUUC-Apl-003512	Anas platyrhynchos	36.65	9.00e-23	99.80
IUUC-Aca-004314	Anolis carolinensis	39.74	1.00e-23	102.00
IUUC-Aly-005494	Arabidopsis lyrata	39.55	2.00e-23	102.00
IUUC-Ath-007211	Arabidopsis thaliana	35.51	2.00e-21	95.90
IUUC-Ame-011659	Astyanax mexicanus	38.62	9.00e-22	96.70
IUUC-Bta-013362	Bos taurus	38.51	8.00e-23	100.00
IUUC-Bdi-014465	Brachypodium distachyon	36.03	9.00e-21	93.60
IUUC-Bol-015191	Brassica oleracea	36.30	7.00e-21	93.60
IUUC-Cja-019177	Callithrix jacchus	39.46	2.00e-23	102.00
IUUC-Cfa-020051	Canis familiaris	39.19	2.00e-23	102.00
IUUC-Cpo-021886	Cavia porcellus	38.51	8.00e-23	100.00
IUUC-Csa-024103	Chlorocebus sabaeus	39.46	3.00e-23	101.00
IUUC-Cho-024315	Choloepus hoffmanni	30.77	9.00e-14	69.70
IUUC-Dno-029409	Dasypus novemcinctus	39.19	9.00e-24	103.00
IUUC-Dor-030443	Dipodomys ordii	37.84	8.00e-23	100.00
IUUC-Ete-032807	Echinops telfairi	38.51	6.00e-23	100.00
IUUC-Eca-033479	Equus caballus	38.51	4.00e-23	100.00
IUUC-Eeu-034835	Erinaceus europaeus	37.84	1.00e-22	99.40
IUUC-Fca-036320	Felis catus	39.19	2.00e-23	102.00
IUUC-Fal-037029	Ficedula albicollis	37.58	1.00e-21	95.90
IUUC-Gga-040823	Gallus gallus	35.19	1.00e-21	95.50
IUUC-Gac-042343	Gasterosteus aculeatus	36.81	1.00e-19	89.40
IUUC-Gma-044402	Glycine max	34.81	7.00e-21	93.60
IUUC-Ggo-045598	Gorilla gorilla	39.46	3.00e-23	101.00
IUUC-Hsa-046598	Homo sapiens	39.46	3.00e-23	101.00
IUUC-Hvu-047146	Hordeum vulgare	36.30	2.00e-21	95.50
IUUC-Itr-047951	Ictidomys tridecemlineatus	38.51	4.00e-23	101.00
IUUC-Lpe-050703	Leersia perrieri	35.29	1.00e-21	96.70
IUUC-Loc-051814	Lepisosteus oculatus	37.67	2.00e-20	92.00
IUUC-Mcc-054661	Macaca mulatta	39.46	3.00e-23	101.00
IUUC-Mtr-057945	Medicago truncatula	37.78	1.00e-22	100.00
IUUC-Mla-059026	Melampsora laricipopulina	34.13	4.00e-14	70.90
IUUC-Mga-059833	Meleagris gallopavo	35.19	1.00e-21	95.50
IUUC-Mmu-063582	Mus musculus	37.84	4.00e-23	100.00
IUUC-Mpu-066339	Mustela putorius furo	38.51	4.00e-23	101.00
IUUC-Mlu-067511	Myotis lucifugus	39.86	2.00e-23	102.00
IUUC-Nle-069252	Nomascus leucogenys	39.46	3.00e-23	101.00
IUUC-Opr-070969	Ochotona princeps	38.51	1.00e-22	99.40
IUUC-Oan-073656	Ornithorhynchus anatinus	34.23	8.00e-20	90.10
IUUC-Ocu-074704	Oryctolagus cuniculus	38.51	3.00e-23	101.00
IUUC-Oba-075094	Oryza barthii	36.03	8.00e-22	97.10
IUUC-Obr-076743	Oryza brachyantha	34.56	6.00e-21	94.40
IUUC-Ogu-078851	Oryza glumaepatula	36.03	8.00e-22	97.10
IUUC-Oin-079402	Oryza indica	36.03	8.00e-22	97.10
IUUC-Olo-080431	Oryza longistaminata	36.03	2.00e-21	95.50
IUUC-Ome-081580	Oryza meridionalis	36.03	7.00e-22	97.10
IUUC-Oni-082644	Oryza nivara	36.03	8.00e-22	97.10
IUUC-Opu-083452	Oryza punctata	36.57	1.00e-21	96.70
IUUC-Oru-084546	Oryza rufipogon	36.03	8.00e-22	97.10
IUUC-Osa-085858	Oryza sativa	36.03	7.00e-22	97.40
IUUC-Ola-087238	Oryzias latipes	36.91	2.00e-18	85.10
IUUC-Oga-088713	Otolemur garnettii	37.84	6.00e-23	100.00
IUUC-Oar-089887	Ovis aries	38.51	1.00e-22	99.80
IUUC-Ptr-091670	Pan troglodytes	39.46	3.00e-23	101.00
IUUC-Pan-092293	Papio anubis	39.46	3.00e-23	101.00
IUUC-Psi-093256	Pelodiscus sinensis	36.77	9.00e-22	96.70
IUUC-Ppa-095584	Physcomitrella patens	41.09	3.00e-24	105.00
IUUC-Pfo-097202	Poecilia formosa	36.24	3.00e-19	88.20
IUUC-Pab-098773	Pongo abelii	39.46	2.00e-23	101.00
IUUC-Pop-099136	Populus trichocarpa	39.71	5.00e-24	103.00
IUUC-Pca-101069	Procavia capensis	38.78	4.00e-23	100.00
IUUC-Ppe-101794	Prunus persica	37.88	1.00e-22	99.40
IUUC-Pva-103092	Pteropus vampyrus	38.51	8.00e-23	100.00
IUUC-Rno-105237	Rattus norvegicus	37.84	4.00e-23	100.00
IUUC-Sha-106889	Sarcophilus harrisii	36.42	8.00e-22	96.70
IUUC-Spo-108149	Schizosaccharomyces pombe	35.10	6.00e-18	84.00
IUUC-Sit-110283	Setaria italica	36.03	9.00e-22	97.10
IUUC-Sly-111491	Solanum lycopersicum	37.40	1.00e-22	99.80
IUUC-Stu-112820	Solanum tuberosum	37.31	1.00e-22	100.00
IUUC-Sbi-113785	Sorghum bicolor	35.29	5.00e-20	90.90
IUUC-Ssc-116091	Sus scrofa	38.51	3.00e-23	101.00
IUUC-Tgu-116907	Taeniopygia guttata	35.54	5.00e-22	97.40
IUUC-Tru-117835	Takifugu rubripes	34.93	9.00e-19	86.70
IUUC-Tni-119716	Tetraodon nigroviridis	34.27	8.00e-19	86.30
IUUC-Tca-121701	Theobroma cacao	37.68	6.00e-23	100.00
IUUC-Tae-125785	Triticum aestivum	37.50	8.00e-19	87.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence