iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033493

Ensembl Protein ID

ENSECAP00000012148.1

UniProt Accession

F7C7X4; F7C7X4_HORSE

Protein Name

Inhibitor of growth protein

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014401.1	ENSECAT00000015144.1	ENSECAP00000012148.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-09	37.3	172	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 172  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 219
           69*.*******99..*********99***********...999997.******87 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

IENLPCELQR NFQLMRELDQ RTEDKKAEID ILAAEYISTV KTLSPDQRVE HLQKIQSAYS 60
KCKEYSDDKV QLAMQTYEMV DKHIRRLDAD LARFEADLKD KMEGSDFESS GGRGLKRGQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATCGAGAA CCTTCCCTGC GAACTTCAGA GGAACTTCCA GCTGATGCGA GAGCTGGACC 60
AGAGGACAGA AGGTGGGCTC AGGGGGCCGG CACGGTGGGC TGCGGCCCGG CTCTGGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	94.27	9.00e-111	392.00
IUUC-Atr-002906	Amborella trichopoda	34.32	2.00e-32	132.00
IUUC-Apl-003516	Anas platyrhynchos	85.78	2.00e-97	347.00
IUUC-Aca-005009	Anolis carolinensis	84.51	1.00e-102	365.00
IUUC-Ame-011879	Astyanax mexicanus	72.81	3.00e-96	344.00
IUUC-Bta-012590	Bos taurus	92.51	1.00e-114	405.00
IUUC-Cja-019518	Callithrix jacchus	83.47	2.00e-114	404.00
IUUC-Cfa-020620	Canis familiaris	98.68	1.00e-125	441.00
IUUC-Cpo-022085	Cavia porcellus	94.27	2.00e-112	397.00
IUUC-Csa-023421	Chlorocebus sabaeus	94.27	2.00e-111	394.00
IUUC-Dre-027588	Danio rerio	75.98	3.00e-96	344.00
IUUC-Fca-035635	Felis catus	100.00	7.00e-57	213.00
IUUC-Fal-036998	Ficedula albicollis	87.22	1.00e-111	395.00
IUUC-Fox-037925	Fusarium oxysporum	59.62	2.00e-19	90.50
IUUC-Gmo-039035	Gadus morhua	76.32	3.00e-95	340.00
IUUC-Gga-040578	Gallus gallus	88.99	2.00e-112	397.00
IUUC-Gac-042172	Gasterosteus aculeatus	73.68	1.00e-96	345.00
IUUC-Hsa-045965	Homo sapiens	94.27	2.00e-111	394.00
IUUC-Loc-052725	Lepisosteus oculatus	81.06	1.00e-95	342.00
IUUC-Mcc-055455	Macaca mulatta	94.27	4.00e-111	393.00
IUUC-Mtr-058089	Medicago truncatula	32.77	2.00e-32	132.00
IUUC-Mga-059312	Meleagris gallopavo	86.14	6.00e-97	346.00
IUUC-Mmr-061351	Microcebus murinus	93.81	4.00e-110	390.00
IUUC-Mdo-062282	Monodelphis domestica	91.63	5.00e-108	383.00
IUUC-Mmu-063201	Mus musculus	93.39	6.00e-114	402.00
IUUC-Mpu-066302	Mustela putorius furo	95.59	4.00e-113	400.00
IUUC-Mlu-068192	Myotis lucifugus	94.27	8.00e-113	399.00
IUUC-Ont-072055	Oreochromis niloticus	76.32	6.00e-94	336.00
IUUC-Oan-073652	Ornithorhynchus anatinus	92.95	5.00e-112	396.00
IUUC-Ocu-073871	Oryctolagus cuniculus	93.86	2.00e-113	400.00
IUUC-Ola-087103	Oryzias latipes	75.11	2.00e-88	318.00
IUUC-Olu-087851	Ostreococcus lucimarinus	42.11	4.00e-20	90.90
IUUC-Oga-088066	Otolemur garnettii	86.10	2.00e-96	344.00
IUUC-Ptr-091665	Pan troglodytes	94.27	2.00e-111	394.00
IUUC-Pan-091875	Papio anubis	94.27	2.00e-111	394.00
IUUC-Psi-093904	Pelodiscus sinensis	88.73	1.00e-104	371.00
IUUC-Pfo-096981	Poecilia formosa	76.75	3.00e-94	337.00
IUUC-Pva-102282	Pteropus vampyrus	93.33	7.00e-119	419.00
IUUC-Rno-105646	Rattus norvegicus	92.95	3.00e-113	400.00
IUUC-Sha-107031	Sarcophilus harrisii	91.63	6.00e-108	382.00
IUUC-Smo-109441	Selaginella moellendorffii	36.64	4.00e-39	154.00
IUUC-Tgu-116837	Taeniopygia guttata	86.78	6.00e-111	392.00
IUUC-Tru-117974	Takifugu rubripes	70.74	2.00e-90	324.00
IUUC-Tni-120024	Tetraodon nigroviridis	75.44	4.00e-82	297.00
IUUC-Tca-121597	Theobroma cacao	36.86	1.00e-31	129.00
IUUC-Vvi-131487	Vitis vinifera	37.61	1.00e-34	139.00
IUUC-Xtr-132189	Xenopus tropicalis	80.80	3.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence