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Tag Content
UUCD2 ID IUUC-Tgu-116901
UUCD1 version UUC-TaG-00545
Ensembl Protein ID ENSTGUP00000010629.1
UniProt Accession H0ZJ61; H0ZJ61_TAEGU
Genbank Protein ID ENSTGUP00000010629
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABQF01013025
Gene Name UBE3A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTGUG00000010281.1 ENSTGUT00000010741.1 ENSTGUP00000010629.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.90e-108 362.6 556 882
Active Site
Position(s) Description Evidence
851 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f+y+e+ k  ++ np+s+    e +  F+++G++lg+a++++ +ld+
   Q: 556  PADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWF-NPSSF----ETEGQFTLIGIVLGLAIYNNCILDV 639
           689******************************************998888876.88888....789********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl++ +p ly+sl  ++e+ e ++e+  + +tf+  +++++g+   ++Lk++G++ip+tneN++e+v+l++
   Q: 640  HFPMVVYRKLMGKKGTFRDLADSHPVLYQSLRDLLEY-EGSVEDD-MMITFQiSHTDLFGNPMMHDLKENGDKIPITNENRKEFVNLYA 726
           *************************************.6677775.999999445566******************************* PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           +y+l++++++q++afr+Gf+ v +++ l  lF++ee+ellicG++++d+++l+++t+y+ggyt+ds  i+ Fwe++++f++e+++ fLq
   Q: 727  DYILNKSVEKQFKAFRRGFHMVTNESpLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSLIIREFWEIVHSFTDEQKRLFLQ 815
           ***********************99934558********************************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+Tg++r+P+gG+ +lk   ++i k++ d +rlP+s+TCfn+L LPeYsske+lke+Ll Ai+++kgF++
   Q: 816  FTTGTDRAPVGGLGKLK---MIIAKNGPDtERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 882
           *****************...8888866666**************************************97 PP
   
Organism Taeniopygia guttata
Protein Sequence
(Fasta)
CHRMATACKR SPGEPHSENI ETSRMKRAAA KHLIERYYHQ LTEGCGNEAC TNEFCASCPT 60
FLRMDNNAAA IKALELYKIN AKLCDPHPSK KGTSSAYLEN NSKGAHNNSC TDRKMNKKEM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tgu-116901|E3,HECT|Taeniopygia guttata
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGCCTGCGC CGCGCCGACA TCCGCGCTGT CCCAAGATGG AGGCGCGGGG CTCGCGCTGA 60
GCGCGGCCCG GCCGGCACAG CAGCAGCAAC AGCAGCAGGA GCAGCAGCCG CGCCCGCCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tgu-116901|E3,HECT|Taeniopygia guttata
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR032353--AZUL
IPR000569--HECT_dom
IPR017134--UBE3A
PROSITE

PS50237--HECT
Pfam

PF16558--AZUL
PF00632--HECT
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0030521--P:androgen receptor signaling pathway
GO:0001541--P:ovarian follicle development
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0060736--P:prostate gland growth
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042752--P:regulation of circadian rhythm
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035037--P:sperm entry
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002214 Ailuropoda melanoleuca 94.87 0.00e+00 1576.00
IUUC-Atr-003144 Amborella trichopoda 45.80 4.00e-97 347.00
IUUC-Apl-003742 Anas platyrhynchos 99.89 0.00e+00 1704.00
IUUC-Aca-004873 Anolis carolinensis 97.17 0.00e+00 1686.00
IUUC-Ame-011166 Astyanax mexicanus 86.51 0.00e+00 1468.00
IUUC-Bta-013286 Bos taurus 93.75 0.00e+00 1557.00
IUUC-Cja-019707 Callithrix jacchus 91.65 0.00e+00 1589.00
IUUC-Cfa-020154 Canis familiaris 93.82 0.00e+00 1587.00
IUUC-Cpo-021292 Cavia porcellus 93.24 0.00e+00 1553.00
IUUC-Cre-022790 Chlamydomonas reinhardtii 49.37 5.00e-82 296.00
IUUC-Csa-023378 Chlorocebus sabaeus 91.59 0.00e+00 1595.00
IUUC-Cho-025059 Choloepus hoffmanni 90.92 0.00e+00 1492.00
IUUC-Cin-025643 Ciona intestinalis 44.20 0.00e+00 707.00
IUUC-Csv-026282 Ciona savignyi 44.53 0.00e+00 667.00
IUUC-Cme-027151 Cyanidioschyzon merolae 44.24 8.00e-102 365.00
IUUC-Dre-027901 Danio rerio 85.58 0.00e+00 1446.00
IUUC-Dno-029320 Dasypus novemcinctus 94.32 0.00e+00 1612.00
IUUC-Dor-030756 Dipodomys ordii 89.80 0.00e+00 708.00
IUUC-Dme-032035 Drosophila melanogaster 42.98 5.00e-166 578.00
IUUC-Eca-033843 Equus caballus 94.29 0.00e+00 1533.00
IUUC-Eeu-035109 Erinaceus europaeus 92.31 0.00e+00 1513.00
IUUC-Fca-036344 Felis catus 93.98 0.00e+00 1605.00
IUUC-Fal-036747 Ficedula albicollis 100.00 0.00e+00 1697.00
IUUC-Gmo-038840 Gadus morhua 63.99 0.00e+00 1112.00
IUUC-Gga-040399 Gallus gallus 99.77 0.00e+00 1694.00
IUUC-Gac-041933 Gasterosteus aculeatus 85.97 0.00e+00 1419.00
IUUC-Ggo-044804 Gorilla gorilla 91.32 0.00e+00 1585.00
IUUC-Hsa-045727 Homo sapiens 91.32 0.00e+00 1585.00
IUUC-Itr-048289 Ictidomys tridecemlineatus 90.68 0.00e+00 1472.00
IUUC-Lch-050197 Latimeria chalumnae 91.76 0.00e+00 1576.00
IUUC-Loc-052743 Lepisosteus oculatus 90.63 0.00e+00 1563.00
IUUC-Lma-053245 Leptosphaeria maculans 35.11 7.00e-58 219.00
IUUC-Laf-053615 Loxodonta africana 92.53 0.00e+00 1593.00
IUUC-Mcc-054934 Macaca mulatta 91.62 0.00e+00 1582.00
IUUC-Meu-056061 Macropus eugenii 96.56 0.00e+00 1366.00
IUUC-Mga-059271 Meleagris gallopavo 97.73 0.00e+00 1647.00
IUUC-Mmr-061288 Microcebus murinus 93.69 0.00e+00 1586.00
IUUC-Mdo-062975 Monodelphis domestica 96.71 0.00e+00 1658.00
IUUC-Mmu-063674 Mus musculus 90.00 0.00e+00 1551.00
IUUC-Mpu-066568 Mustela putorius furo 94.55 0.00e+00 1619.00
IUUC-Mlu-067522 Myotis lucifugus 86.28 0.00e+00 1484.00
IUUC-Nle-069505 Nomascus leucogenys 91.32 0.00e+00 1585.00
IUUC-Opr-070570 Ochotona princeps 87.57 0.00e+00 1428.00
IUUC-Ont-071527 Oreochromis niloticus 86.56 0.00e+00 1484.00
IUUC-Oan-073446 Ornithorhynchus anatinus 90.20 0.00e+00 1075.00
IUUC-Ocu-074922 Oryctolagus cuniculus 93.21 0.00e+00 1602.00
IUUC-Ola-086996 Oryzias latipes 84.22 0.00e+00 1483.00
IUUC-Oga-088261 Otolemur garnettii 94.29 0.00e+00 1565.00
IUUC-Oar-090024 Ovis aries 93.75 0.00e+00 1557.00
IUUC-Ptr-090455 Pan troglodytes 91.32 0.00e+00 1585.00
IUUC-Pan-092509 Papio anubis 88.99 0.00e+00 1416.00
IUUC-Psi-092974 Pelodiscus sinensis 96.94 0.00e+00 1654.00
IUUC-Pma-094643 Petromyzon marinus 71.40 0.00e+00 1256.00
IUUC-Pno-094886 Phaeosphaeria nodorum 35.84 3.00e-59 223.00
IUUC-Ppa-095354 Physcomitrella patens 46.61 2.00e-111 396.00
IUUC-Pfo-096905 Poecilia formosa 85.11 0.00e+00 1478.00
IUUC-Pab-097840 Pongo abelii 91.39 0.00e+00 1526.00
IUUC-Pca-100869 Procavia capensis 93.95 0.00e+00 1576.00
IUUC-Pva-103040 Pteropus vampyrus 95.83 0.00e+00 660.00
IUUC-Rno-105453 Rattus norvegicus 89.55 0.00e+00 1543.00
IUUC-Sha-107651 Sarcophilus harrisii 96.71 0.00e+00 1659.00
IUUC-Smo-108858 Selaginella moellendorffii 49.88 2.00e-115 409.00
IUUC-Sar-113293 Sorex araneus 94.30 0.00e+00 1565.00
IUUC-Ssc-115979 Sus scrofa 94.41 0.00e+00 1565.00
IUUC-Tru-118368 Takifugu rubripes 86.44 0.00e+00 1481.00
IUUC-Tsy-119516 Tarsius syrichta 90.33 0.00e+00 1457.00
IUUC-Tni-120143 Tetraodon nigroviridis 86.44 0.00e+00 1479.00
IUUC-Tbe-127484 Tupaia belangeri 88.73 0.00e+00 1068.00
IUUC-Ttr-129078 Tursiops truncatus 94.06 0.00e+00 1536.00
IUUC-Vpa-130312 Vicugna pacos 86.43 0.00e+00 1315.00
IUUC-Xtr-132881 Xenopus tropicalis 90.50 0.00e+00 1597.00
Created Date 25-Jun-2017

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