iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061914

Ensembl Protein ID

ENSMODP00000020529.3

UniProt Accession

F7ASA8; F7ASA8_MONDO

Protein Name

Uncharacterized protein

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016435.3	ENSMODT00000020893.3	ENSMODP00000020529.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	78.35	5.00e-176	614.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDISKENSVS GPSNKTAILL GEGPKRVPIT QQISSQSRLP GSSGQAQRVL CSSNPLLVSS 60
QAQKNISSHK TSHAHQSQKL QQAPVIHPTS RPPSSTQNTE QSQPPVSASI PGKGETPRQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGGGCTG GACCTTTCTG CTCTCAGTCC CTCTCAGGAA TCCCCACTCC CTACCAGCCG 60
GAGATAGGCT CGGCTTCCGG CCTCCTGGGG TTCAGTCTTC GGCCCGGACC CCTCACAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

mdo:100027920

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	65.82	1.00e-105	375.00
IUUC-Aml-001426	Ailuropoda melanoleuca	79.34	6.00e-179	620.00
IUUC-Atr-002453	Amborella trichopoda	66.91	4.00e-109	387.00
IUUC-Apl-003626	Anas platyrhynchos	73.18	2.00e-157	548.00
IUUC-Aca-004602	Anolis carolinensis	69.63	4.00e-155	540.00
IUUC-Aly-005878	Arabidopsis lyrata	65.09	7.00e-107	379.00
IUUC-Ath-007117	Arabidopsis thaliana	65.58	2.00e-107	381.00
IUUC-Acl-008199	Aspergillus clavatus	57.46	3.00e-87	315.00
IUUC-Afl-008419	Aspergillus flavus	58.69	8.00e-87	313.00
IUUC-Afu-008751	Aspergillus fumigatus	57.46	5.00e-87	314.00
IUUC-Ani-009181	Aspergillus nidulans	50.76	3.00e-92	331.00
IUUC-Ang-009787	Aspergillus niger	53.72	1.00e-88	319.00
IUUC-Aor-009980	Aspergillus oryzae	58.69	8.00e-87	313.00
IUUC-Ate-010286	Aspergillus terreus	53.25	4.00e-88	318.00
IUUC-Ame-010849	Astyanax mexicanus	60.16	4.00e-129	454.00
IUUC-Bgr-012110	Blumeria graminis	51.14	2.00e-88	319.00
IUUC-Bta-013474	Bos taurus	79.12	9.00e-180	622.00
IUUC-Bci-013756	Botrytis cinerea	55.33	1.00e-94	339.00
IUUC-Bdi-014257	Brachypodium distachyon	66.18	6.00e-106	376.00
IUUC-Bol-016310	Brassica oleracea	64.87	1.00e-104	372.00
IUUC-Bra-017438	Brassica rapa	65.07	1.00e-105	375.00
IUUC-Cel-018157	Caenorhabditis elegans	60.21	3.00e-102	364.00
IUUC-Cja-019282	Callithrix jacchus	77.06	3.00e-170	591.00
IUUC-Cfa-020162	Canis familiaris	78.57	2.00e-178	618.00
IUUC-Cpo-021764	Cavia porcellus	76.41	1.00e-166	579.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	68.56	3.00e-109	387.00
IUUC-Csa-023694	Chlorocebus sabaeus	78.35	6.00e-164	570.00
IUUC-Cho-024350	Choloepus hoffmanni	92.86	5.00e-107	379.00
IUUC-Cin-025542	Ciona intestinalis	74.52	2.00e-118	418.00
IUUC-Csv-025873	Ciona savignyi	67.92	1.00e-120	425.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	56.20	1.00e-80	293.00
IUUC-Cne-026928	Cryptococcus neoformans	61.87	2.00e-96	346.00
IUUC-Cme-027336	Cyanidioschyzon merolae	71.02	1.00e-120	426.00
IUUC-Dre-028198	Danio rerio	58.96	1.00e-131	462.00
IUUC-Dno-029928	Dasypus novemcinctus	80.41	1.00e-175	608.00
IUUC-Dor-030238	Dipodomys ordii	70.36	7.00e-153	533.00
IUUC-Dse-031266	Dothistroma septosporum	54.61	4.00e-93	334.00
IUUC-Dme-032007	Drosophila melanogaster	62.45	1.00e-101	363.00
IUUC-Ete-032911	Echinops telfairi	61.10	1.00e-116	413.00
IUUC-Eca-033749	Equus caballus	79.12	4.00e-178	617.00
IUUC-Eeu-035170	Erinaceus europaeus	76.09	3.00e-168	584.00
IUUC-Fca-035498	Felis catus	80.16	5.00e-176	610.00
IUUC-Fal-037397	Ficedula albicollis	68.49	2.00e-151	528.00
IUUC-Fox-037747	Fusarium oxysporum	51.80	3.00e-92	332.00
IUUC-Fso-038429	Fusarium solani	53.23	9.00e-90	323.00
IUUC-Gmo-039378	Gadus morhua	58.14	8.00e-127	446.00
IUUC-Ggr-039939	Gaeumannomyces graminis	62.36	8.00e-96	343.00
IUUC-Gga-040187	Gallus gallus	70.57	5.00e-154	537.00
IUUC-Gac-042223	Gasterosteus aculeatus	60.68	1.00e-132	466.00
IUUC-Gma-042870	Glycine max	67.29	2.00e-100	358.00
IUUC-Ggo-045617	Gorilla gorilla	78.61	8.00e-178	616.00
IUUC-Hsa-046968	Homo sapiens	78.35	2.00e-177	614.00
IUUC-Hvu-047072	Hordeum vulgare	55.94	8.00e-82	296.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	67.27	3.00e-142	498.00
IUUC-Kpa-049093	Komagataella pastoris	57.09	1.00e-79	289.00
IUUC-Lch-050346	Latimeria chalumnae	68.83	5.00e-149	520.00
IUUC-Lpe-051466	Leersia perrieri	69.20	1.00e-107	382.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	2.00e-90	325.00
IUUC-Laf-053422	Loxodonta africana	79.12	1.00e-178	619.00
IUUC-Mcc-055245	Macaca mulatta	78.35	8.00e-164	569.00
IUUC-Mor-056952	Magnaporthe oryzae	58.94	1.00e-91	329.00
IUUC-Mpo-057605	Magnaporthe poae	60.52	4.00e-96	344.00
IUUC-Mtr-057726	Medicago truncatula	67.42	9.00e-107	379.00
IUUC-Mla-059174	Melampsora laricipopulina	63.08	2.00e-100	359.00
IUUC-Mga-059562	Meleagris gallopavo	61.40	1.00e-120	426.00
IUUC-Mvi-060305	Microbotryum violaceum	61.22	8.00e-94	337.00
IUUC-Mmr-061588	Microcebus murinus	77.78	6.00e-175	606.00
IUUC-Mmu-063288	Mus musculus	75.71	5.00e-166	577.00
IUUC-Mac-064969	Musa acuminata	68.56	1.00e-107	382.00
IUUC-Mpu-066855	Mustela putorius furo	78.87	1.00e-177	615.00
IUUC-Mlu-068046	Myotis lucifugus	78.61	2.00e-176	611.00
IUUC-Nfi-068527	Neosartorya fischeri	57.84	4.00e-87	315.00
IUUC-Ncr-068678	Neurospora crassa	59.85	3.00e-92	332.00
IUUC-Nle-069848	Nomascus leucogenys	77.58	6.00e-176	610.00
IUUC-Opr-070589	Ochotona princeps	73.47	4.00e-160	557.00
IUUC-Ont-071733	Oreochromis niloticus	61.11	4.00e-125	441.00
IUUC-Oan-073399	Ornithorhynchus anatinus	92.58	7.00e-160	556.00
IUUC-Ocu-074063	Oryctolagus cuniculus	77.00	3.00e-173	600.00
IUUC-Oba-075264	Oryza barthii	68.82	2.00e-106	378.00
IUUC-Obr-076048	Oryza brachyantha	67.92	2.00e-106	378.00
IUUC-Ogl-077637	Oryza glaberrima	68.82	3.00e-106	377.00
IUUC-Ogu-078830	Oryza glumaepatula	68.82	2.00e-106	378.00
IUUC-Oin-079150	Oryza indica	68.82	1.00e-106	379.00
IUUC-Olo-080398	Oryza longistaminata	54.61	1.00e-84	305.00
IUUC-Ome-081544	Oryza meridionalis	57.36	7.00e-92	330.00
IUUC-Oni-082250	Oryza nivara	68.82	1.00e-106	379.00
IUUC-Opu-083638	Oryza punctata	68.30	2.00e-106	378.00
IUUC-Oru-084981	Oryza rufipogon	68.82	9.00e-107	379.00
IUUC-Osa-085961	Oryza sativa	68.82	9.00e-107	379.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.73	3.00e-110	391.00
IUUC-Oga-088891	Otolemur garnettii	79.33	1.00e-178	618.00
IUUC-Oar-090021	Ovis aries	79.12	4.00e-174	603.00
IUUC-Ptr-091458	Pan troglodytes	78.61	1.00e-177	615.00
IUUC-Pan-092546	Papio anubis	78.35	1.00e-163	569.00
IUUC-Psi-093280	Pelodiscus sinensis	76.42	1.00e-168	585.00
IUUC-Pma-094298	Petromyzon marinus	80.15	2.00e-124	437.00
IUUC-Pno-094847	Phaeosphaeria nodorum	51.36	1.00e-90	326.00
IUUC-Ppa-095855	Physcomitrella patens	64.00	2.00e-107	382.00
IUUC-Pfo-096428	Poecilia formosa	61.79	2.00e-127	448.00
IUUC-Pab-098696	Pongo abelii	78.66	7.00e-174	603.00
IUUC-Pop-099405	Populus trichocarpa	63.54	8.00e-107	379.00
IUUC-Pca-100740	Procavia capensis	75.77	2.00e-170	591.00
IUUC-Ppe-101854	Prunus persica	67.67	1.00e-107	382.00
IUUC-Pva-103212	Pteropus vampyrus	77.06	3.00e-174	604.00
IUUC-Pgr-103474	Puccinia graminis	63.26	8.00e-100	357.00
IUUC-Ptt-103933	Puccinia triticina	48.85	6.00e-62	231.00
IUUC-Pte-104089	Pyrenophora teres	59.32	3.00e-90	325.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	59.32	4.00e-90	325.00
IUUC-Rno-105057	Rattus norvegicus	76.67	5.00e-168	583.00
IUUC-Sha-107137	Sarcophilus harrisii	93.52	0.00e+00	743.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	62.69	4.00e-101	360.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.85	4.00e-103	367.00
IUUC-Smo-109288	Selaginella moellendorffii	66.91	2.00e-108	384.00
IUUC-Sit-110246	Setaria italica	63.03	7.00e-106	376.00
IUUC-Sly-111379	Solanum lycopersicum	65.69	4.00e-107	380.00
IUUC-Stu-112777	Solanum tuberosum	67.05	1.00e-106	379.00
IUUC-Sbi-114325	Sorghum bicolor	64.41	9.00e-106	376.00
IUUC-Sre-115203	Sporisorium reilianum	59.40	2.00e-82	299.00
IUUC-Ssc-115361	Sus scrofa	77.32	4.00e-174	603.00
IUUC-Tgu-116967	Taeniopygia guttata	72.04	6.00e-149	520.00
IUUC-Tru-117570	Takifugu rubripes	62.67	4.00e-134	471.00
IUUC-Tsy-119280	Tarsius syrichta	59.23	2.00e-114	405.00
IUUC-Tni-120721	Tetraodon nigroviridis	63.40	5.00e-134	470.00
IUUC-Tca-121494	Theobroma cacao	63.38	2.00e-106	378.00
IUUC-Tre-121869	Trichoderma reesei	53.25	1.00e-93	336.00
IUUC-Tvi-122510	Trichoderma virens	61.36	8.00e-93	333.00
IUUC-Tae-123071	Triticum aestivum	65.82	1.00e-105	375.00
IUUC-Tur-126240	Triticum urartu	65.82	3.00e-105	374.00
IUUC-Tme-126921	Tuber melanosporum	62.69	8.00e-97	347.00
IUUC-Tbe-127872	Tupaia belangeri	74.53	3.00e-155	541.00
IUUC-Ttr-129134	Tursiops truncatus	77.55	8.00e-175	606.00
IUUC-Uma-129412	Ustilago maydis	59.02	9.00e-80	290.00
IUUC-Vda-130003	Verticillium dahliae	47.59	1.00e-91	329.00
IUUC-Vvi-131272	Vitis vinifera	67.29	3.00e-107	380.00
IUUC-Xtr-132019	Xenopus tropicalis	68.60	3.00e-152	531.00
IUUC-Xma-134203	Xiphophorus maculatus	62.57	2.00e-134	472.00
IUUC-Yli-134503	Yarrowia lipolytica	55.38	8.00e-89	320.00
IUUC-Zma-135232	Zea mays	63.38	2.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence