iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053449

UUCD1 version

UUC-LoA-00100

Ensembl Protein ID

ENSLAFP00000002461.3

UniProt Accession

G3SRF4; G3SRF4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000002953.3	ENSLAFT00000002953.3	ENSLAFP00000002461.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.75	0.00e+00	1045.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

KTTFQRLVPS SPQRKYKNIM EDSKILSDWT NSNKQKMKYD FSCELYRMST YSTFPTGVPI 60
SERSLARAGF YYTGVNDKVK CFCCGLMLDN WKQGDNAIEK HKQLYPSCSF IQNLASVTSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACTACCT TCCAAAGACT TGTCCCAAGT TCCCCTCAAC GAAAATATAA GAATATAATG 60
GAAGATAGCA AGATCTTGTC AGATTGGACA AACAGCAACA AACAAAAAAT GAAATACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:0070266--P:necroptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	85.95	0.00e+00	1061.00
IUUC-Atr-002499	Amborella trichopoda	44.64	3.00e-12	65.90
IUUC-Apl-003549	Anas platyrhynchos	71.15	0.00e+00	857.00
IUUC-Aca-004515	Anolis carolinensis	68.70	0.00e+00	790.00
IUUC-Aly-006460	Arabidopsis lyrata	37.04	2.00e-09	56.20
IUUC-Acl-008330	Aspergillus clavatus	30.11	2.00e-14	74.30
IUUC-Afl-008648	Aspergillus flavus	30.86	2.00e-15	77.80
IUUC-Ani-009424	Aspergillus nidulans	29.71	6.00e-14	73.20
IUUC-Ang-009667	Aspergillus niger	29.88	3.00e-12	67.40
IUUC-Ame-011877	Astyanax mexicanus	54.20	0.00e+00	642.00
IUUC-Bta-012450	Bos taurus	85.41	0.00e+00	940.00
IUUC-Cja-018895	Callithrix jacchus	87.42	0.00e+00	1023.00
IUUC-Cfa-020419	Canis familiaris	86.11	0.00e+00	1044.00
IUUC-Cpo-022048	Cavia porcellus	85.30	0.00e+00	1018.00
IUUC-Cho-024277	Choloepus hoffmanni	84.33	0.00e+00	984.00
IUUC-Cin-025521	Ciona intestinalis	30.20	3.00e-76	279.00
IUUC-Dre-028647	Danio rerio	54.04	0.00e+00	632.00
IUUC-Dor-030796	Dipodomys ordii	72.57	1.00e-95	343.00
IUUC-Eca-033393	Equus caballus	89.52	0.00e+00	1050.00
IUUC-Eeu-035114	Erinaceus europaeus	80.48	0.00e+00	956.00
IUUC-Fca-036034	Felis catus	84.65	0.00e+00	1014.00
IUUC-Fal-037656	Ficedula albicollis	70.08	0.00e+00	848.00
IUUC-Fso-038452	Fusarium solani	30.65	4.00e-13	70.10
IUUC-Gga-040601	Gallus gallus	70.73	0.00e+00	862.00
IUUC-Ggo-044857	Gorilla gorilla	87.72	0.00e+00	1034.00
IUUC-Hsa-045769	Homo sapiens	88.05	0.00e+00	1038.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	86.41	0.00e+00	1041.00
IUUC-Lch-050259	Latimeria chalumnae	60.94	0.00e+00	720.00
IUUC-Mga-059947	Meleagris gallopavo	70.73	0.00e+00	862.00
IUUC-Mvi-060388	Microbotryum violaceum	25.13	7.00e-07	48.90
IUUC-Mdo-062352	Monodelphis domestica	77.01	0.00e+00	923.00
IUUC-Mmu-064340	Mus musculus	81.73	0.00e+00	979.00
IUUC-Mpu-065890	Mustela putorius furo	86.19	0.00e+00	959.00
IUUC-Mlu-068077	Myotis lucifugus	88.26	0.00e+00	1058.00
IUUC-Nfi-068591	Neosartorya fischeri	30.49	1.00e-13	72.40
IUUC-Nle-070081	Nomascus leucogenys	86.91	0.00e+00	1033.00
IUUC-Opr-070561	Ochotona princeps	81.07	0.00e+00	963.00
IUUC-Ont-071776	Oreochromis niloticus	52.74	1.00e-178	619.00
IUUC-Oan-073604	Ornithorhynchus anatinus	75.53	0.00e+00	896.00
IUUC-Ocu-073963	Oryctolagus cuniculus	85.86	0.00e+00	1004.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	4.00e-07	49.30
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.00
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Oga-087976	Otolemur garnettii	88.05	0.00e+00	1048.00
IUUC-Oar-090097	Ovis aries	85.90	0.00e+00	1055.00
IUUC-Ptr-091137	Pan troglodytes	87.88	0.00e+00	1037.00
IUUC-Pan-092673	Papio anubis	88.69	0.00e+00	1046.00
IUUC-Pma-094277	Petromyzon marinus	36.59	8.00e-109	387.00
IUUC-Ppa-095167	Physcomitrella patens	42.86	2.00e-11	63.50
IUUC-Pab-098734	Pongo abelii	89.50	0.00e+00	1023.00
IUUC-Pop-098944	Populus trichocarpa	42.59	4.00e-10	58.50
IUUC-Pca-100708	Procavia capensis	75.85	6.00e-178	616.00
IUUC-Pva-102788	Pteropus vampyrus	88.05	0.00e+00	1033.00
IUUC-Rno-105026	Rattus norvegicus	79.97	0.00e+00	935.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	34.42	3.00e-16	80.90
IUUC-Stu-112233	Solanum tuberosum	45.83	5.00e-09	55.10
IUUC-Ssc-115804	Sus scrofa	83.88	0.00e+00	998.00
IUUC-Tgu-116931	Taeniopygia guttata	69.59	0.00e+00	855.00
IUUC-Tru-117620	Takifugu rubripes	52.13	4.00e-176	611.00
IUUC-Tni-119683	Tetraodon nigroviridis	52.42	1.00e-174	605.00
IUUC-Tbe-127523	Tupaia belangeri	86.59	0.00e+00	1050.00
IUUC-Ttr-128954	Tursiops truncatus	85.65	0.00e+00	1010.00
IUUC-Vpa-130441	Vicugna pacos	87.24	0.00e+00	1041.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence