iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090097

Ensembl Protein ID

ENSOARP00000006949.1

UniProt Accession

W5P941; W5P941_SHEEP

Genbank Protein ID

ENSOARP00000006949

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01030406

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000006491.1	ENSOART00000007056.1	ENSOARP00000006949.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.62	0.00e+00	1085.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MHKTTSQRLV LDPSYRKIKS VMEDSTVLSN WTSGNKQKMT YDFSCELYRM STYSTFPTGV 60
PVSERSLARA GFYYTGVNDK VKCFCCGLML DNWKQGDNPI EKHKQLYPSC SFIQNLVSVT 120

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Nucleotide Sequence
(Fasta)

ATGCACAAAA CTACCTCCCA AAGACTTGTC CTGGATCCCT CGTATCGAAA AATTAAGAGT 60
GTGATGGAAG ATAGCACAGT CTTGTCAAAT TGGACAAGTG GCAACAAACA AAAAATGACA 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:0070266--P:necroptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

KEGG

oas:101119930

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	87.22	0.00e+00	1086.00
IUUC-Atr-002499	Amborella trichopoda	44.64	4.00e-12	65.50
IUUC-Apl-003549	Anas platyrhynchos	69.12	0.00e+00	835.00
IUUC-Aca-004515	Anolis carolinensis	66.89	0.00e+00	793.00
IUUC-Aly-006460	Arabidopsis lyrata	32.39	1.00e-09	57.00
IUUC-Ath-007365	Arabidopsis thaliana	43.48	7.00e-08	55.50
IUUC-Ame-011877	Astyanax mexicanus	55.05	0.00e+00	646.00
IUUC-Bta-012450	Bos taurus	95.68	0.00e+00	1053.00
IUUC-Bol-015478	Brassica oleracea	34.45	4.00e-09	59.70
IUUC-Bra-017001	Brassica rapa	35.29	2.00e-09	60.80
IUUC-Cel-018418	Caenorhabditis elegans	40.00	2.00e-08	53.50
IUUC-Cja-018895	Callithrix jacchus	87.84	0.00e+00	1048.00
IUUC-Cfa-020419	Canis familiaris	88.30	0.00e+00	1088.00
IUUC-Cpo-022048	Cavia porcellus	86.68	0.00e+00	1064.00
IUUC-Cho-024277	Choloepus hoffmanni	84.94	0.00e+00	1011.00
IUUC-Cin-025521	Ciona intestinalis	30.61	6.00e-76	278.00
IUUC-Csv-026182	Ciona savignyi	30.72	4.00e-67	249.00
IUUC-Dre-028647	Danio rerio	55.05	0.00e+00	637.00
IUUC-Dno-029509	Dasypus novemcinctus	81.55	0.00e+00	955.00
IUUC-Dor-030796	Dipodomys ordii	70.34	2.00e-93	336.00
IUUC-Eca-033393	Equus caballus	93.37	0.00e+00	1097.00
IUUC-Eeu-035114	Erinaceus europaeus	83.81	0.00e+00	984.00
IUUC-Fca-036034	Felis catus	87.50	0.00e+00	1056.00
IUUC-Fal-037656	Ficedula albicollis	68.40	0.00e+00	830.00
IUUC-Fox-037889	Fusarium oxysporum	30.46	7.00e-15	76.30
IUUC-Fso-038452	Fusarium solani	31.40	4.00e-14	73.60
IUUC-Gmo-038477	Gadus morhua	54.49	5.00e-176	610.00
IUUC-Gga-040601	Gallus gallus	69.38	0.00e+00	847.00
IUUC-Gac-041467	Gasterosteus aculeatus	55.18	7.00e-177	613.00
IUUC-Ggo-044857	Gorilla gorilla	88.30	0.00e+00	1063.00
IUUC-Hsa-045769	Homo sapiens	88.62	0.00e+00	1066.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	86.89	0.00e+00	1072.00
IUUC-Lch-050259	Latimeria chalumnae	60.26	0.00e+00	716.00
IUUC-Loc-052169	Lepisosteus oculatus	54.02	4.00e-167	581.00
IUUC-Laf-053449	Loxodonta africana	85.10	0.00e+00	1025.00
IUUC-Mtr-058211	Medicago truncatula	34.62	3.00e-09	59.70
IUUC-Mga-059947	Meleagris gallopavo	69.48	0.00e+00	849.00
IUUC-Mvi-060388	Microbotryum violaceum	25.50	2.00e-08	54.70
IUUC-Mdo-062352	Monodelphis domestica	75.76	0.00e+00	904.00
IUUC-Mmu-064340	Mus musculus	80.35	0.00e+00	973.00
IUUC-Mac-065489	Musa acuminata	36.73	3.00e-08	52.40
IUUC-Mpu-065890	Mustela putorius furo	87.30	0.00e+00	979.00
IUUC-Mlu-068077	Myotis lucifugus	89.44	0.00e+00	1085.00
IUUC-Nle-070081	Nomascus leucogenys	88.46	0.00e+00	1065.00
IUUC-Opr-070561	Ochotona princeps	81.09	0.00e+00	962.00
IUUC-Ont-071776	Oreochromis niloticus	53.81	2.00e-180	625.00
IUUC-Oan-073604	Ornithorhynchus anatinus	74.75	0.00e+00	877.00
IUUC-Ocu-073963	Oryctolagus cuniculus	87.73	0.00e+00	1023.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	4.00e-07	49.30
IUUC-Olo-080871	Oryza longistaminata	39.58	2.00e-06	48.10
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.00
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Ola-086446	Oryzias latipes	52.39	8.00e-172	597.00
IUUC-Oga-087976	Otolemur garnettii	88.78	0.00e+00	1075.00
IUUC-Ptr-091137	Pan troglodytes	88.78	0.00e+00	1067.00
IUUC-Pan-092673	Papio anubis	89.90	0.00e+00	1080.00
IUUC-Ppa-095167	Physcomitrella patens	42.86	2.00e-11	63.20
IUUC-Pfo-096790	Poecilia formosa	53.15	1.00e-174	606.00
IUUC-Pab-098734	Pongo abelii	89.72	0.00e+00	1041.00
IUUC-Pop-098944	Populus trichocarpa	42.59	5.00e-10	58.50
IUUC-Pca-100708	Procavia capensis	70.56	8.00e-171	593.00
IUUC-Pva-102788	Pteropus vampyrus	90.54	0.00e+00	1087.00
IUUC-Rno-105026	Rattus norvegicus	78.77	0.00e+00	936.00
IUUC-Sha-107229	Sarcophilus harrisii	69.81	0.00e+00	836.00
IUUC-Stu-112233	Solanum tuberosum	45.83	6.00e-09	54.70
IUUC-Ssc-115804	Sus scrofa	88.94	0.00e+00	1070.00
IUUC-Tgu-116931	Taeniopygia guttata	69.06	0.00e+00	842.00
IUUC-Tru-117620	Takifugu rubripes	54.75	3.00e-176	612.00
IUUC-Tni-119683	Tetraodon nigroviridis	53.69	2.00e-174	605.00
IUUC-Tre-121884	Trichoderma reesei	31.65	3.00e-12	67.40
IUUC-Tvi-122552	Trichoderma virens	31.65	1.00e-12	68.60
IUUC-Tbe-127523	Tupaia belangeri	88.14	0.00e+00	1082.00
IUUC-Ttr-128954	Tursiops truncatus	89.26	0.00e+00	1075.00
IUUC-Vpa-130441	Vicugna pacos	89.57	0.00e+00	1080.00
IUUC-Xtr-132031	Xenopus tropicalis	57.80	0.00e+00	653.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence