iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125438

Ensembl Protein ID

TRIAE_CS42_3AL_TGACv1_194150_AA0627510.2

UniProt Accession

A0A1D5V6S9; A0A1D5V6S9_WHEAT

Protein Name

Katanin p80 WD40 repeat-containing subunit B1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_3AL_TGACv1_194150_AA0627510	TRIAE_CS42_3AL_TGACv1_194150_AA0627510.1	TRIAE_CS42_3AL_TGACv1_194150_AA0627510.1
TRIAE_CS42_3AL_TGACv1_194150_AA0627510	TRIAE_CS42_3AL_TGACv1_194150_AA0627510.2	TRIAE_CS42_3AL_TGACv1_194150_AA0627510.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.00e-37	126.1	142	180
UBD/Beta-Prp	5.00e-65	222.3	10	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH + + +++f +d + +v+G+ D+ +kvWDl+ g+ll+
   Q: 142  GHRGAIKSIRFtPDgRWIVTGGEDNIVKVWDLTAGKLLH 180
           8***********9999*******************9986 PP

UBD/Beta-Prp

   S: 87   vhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvs 154
           ++ + +h+++v+sl++ + s+ ++++G++dr +++w + +++ l   lsgh+++v  v+++  + l+ +
   Q: 10   FQEFVAHDAEVRSLAIGKkSSRVFITGGSDRNVNLWAIGKQTPLL-SLSGHTSSVEAVEFDTAEVLVLA 77
           667789************666************************.*********************** PP
   S: 155  GslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           Gs ++ ++lWdl+ +k++r ltg h +s + ++f++ g++++sgs d+++k+wd++++ c++t++gh+ 
   Q: 78   GSSNGSIKLWDLEEAKVVRSLTG-HRSSCTAVEFHPFGEFFASGSSDTDLKIWDIKKKGCLHTYKGHRG 145
           **********************9.********************************************* PP
   S: 224  nvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
            +ks+rf+p++ ++v+g++D+ +++Wdl+ g+ll+ ++ h
   Q: 146  AIKSIRFTPDGRWIVTGGEDNIVKVWDLTAGKLLHDFKFH 185
           ***********************************99866 PP

Organism

Triticum aestivum

Functional Description
(View)

May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.

Protein Sequence
(Fasta)

MDPEKRGYKF QEFVAHDAEV RSLAIGKKSS RVFITGGSDR NVNLWAIGKQ TPLLSLSGHT 60
SSVEAVEFDT AEVLVLAGSS NGSIKLWDLE EAKVVRSLTG HRSSCTAVEF HPFGEFFASG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTTTGGT ACAAAAAAGA AAAGAAACGA GACCAAAAGC GAAGCCAAGG GGAAGGGGCA 60
GGAGGACCCA GGAGAGAGAA AGGACGACAA AAACTCCACT CTCCCACCCA CCCACGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0051013--P:microtubule severing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002899	Amborella trichopoda	45.55	0.00e+00	657.00
IUUC-Ath-006624	Arabidopsis thaliana	71.43	2.00e-148	520.00
IUUC-Bol-015355	Brassica oleracea	70.50	1.00e-146	514.00
IUUC-Hvu-047729	Hordeum vulgare	95.63	0.00e+00	1196.00
IUUC-Mtr-057706	Medicago truncatula	48.47	1.00e-147	518.00
IUUC-Mac-065245	Musa acuminata	54.69	0.00e+00	636.00
IUUC-Ncr-068688	Neurospora crassa	30.94	2.00e-27	118.00
IUUC-Pop-100006	Populus trichocarpa	49.92	3.00e-161	563.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence