iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pyt-104713

Ensembl Protein ID

EDU48353

UniProt Accession

B2W6J5; B2W6J5_PYRTR

Genbank Protein ID

EDU48353.1

Protein Name

E3 ubiquitin-protein ligase HUWE1

Genbank Nucleotide ID

DS231619

Gene Name

PTRG_05433

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTRG_05433	EDU48353	EDU48353

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.70e-118	394.5	3596	3928

Active Site

Position(s)	Description	Evidence
3897	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
           +++k+ +l ++f gEeg+d+gGvtre+++ +s++++n+d+ lf+  ++d++t++pn+ s + npehl +F+f+Gr++gkal++gr+ld+++s+++yk++
   Q: 3596 DEMKYgKLSIRFHGEEGVDAGGVTREWFQSISRQMFNADYALFVPVASDRTTFHPNRLSSI-NPEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKQI 3693
           567755899***************************************************9.89*********************************** PP
   S: 101  lgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfne 199
           +gk++sl+d+e++d e+yksl+++ +n   +i+++ ++ tfsv+ e +ge+++++L+++G+nipVt++Nk+eYv+l++e+rl+  ++eq+e+f +Gf++
   Q: 3694 MGKQVSLKDMETLDLEYYKSLEWMIHN---EITDI-ITETFSVEVEAFGEMQTVDLIENGRNIPVTEDNKHEYVRLITEHRLTGAVHEQLENFLKGFHD 3788
           *************************99...89998.999************************************************************ PP
   S: 200  viplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.da 293
           ++p el+s+F+e+elelli+G ++i+v+d+k++t+y++ yt+ sp+iqwFw++++ f++ee++++LqFvTg+s++Pl+Gf+el+     ++f i++ ++
   Q: 3789 IVPAELVSIFSEQELELLISGLPDINVDDWKNNTEYHN-YTAASPQIQWFWRAVRTFEKEEQAKLLQFVTGTSKVPLNGFKELEgmngFSKFNIHRdYG 3886
           ************************************66.*********************************************999966677777699 PP
   S: 294  sddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           s+drlPss+TCfn+L+LPeY+++e l++ L +A++ + + F+
   Q: 3887 SKDRLPSSHTCFNQLDLPEYETYEDLRKALYTAMTAGgEYFG 3928
           99********************************99877776 PP

Organism

Pyrenophora triticirepentis

Protein Sequence
(Fasta)

MKIKKQATSR HESTLSSMIA DFVKATESIP LFQLPAHLAS FPRHWPFPRG DAYHWIPALN 60
RFDHILELFN KEYALVDGPQ TQPFQRRLLL KGDVEEGSPS SNQTTTDAVL DTLHVSKDGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCACGCCG GCTCTATAAC CCAGGCAGCT CAGTTGTACC TGAGCCTTCC CGGGACTTTG 60
CAACTTTCGC TTCTGTTTGA CTCAAGTGAC AACCTAAATA CATCATCACG ACCCCGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	31.21	1.00e-118	421.00
IUUC-Aml-001684	Ailuropoda melanoleuca	52.41	2.00e-133	470.00
IUUC-Atr-003044	Amborella trichopoda	37.14	4.00e-134	472.00
IUUC-Apl-003729	Anas platyrhynchos	50.14	4.00e-98	349.00
IUUC-Aca-005263	Anolis carolinensis	52.87	2.00e-134	474.00
IUUC-Aly-006157	Arabidopsis lyrata	39.23	5.00e-136	479.00
IUUC-Ath-007472	Arabidopsis thaliana	38.35	2.00e-128	453.00
IUUC-Ago-008005	Ashbya gossypii	55.89	0.00e+00	725.00
IUUC-Acl-008254	Aspergillus clavatus	61.01	0.00e+00	1289.00
IUUC-Afl-008712	Aspergillus flavus	61.63	0.00e+00	1333.00
IUUC-Afu-009022	Aspergillus fumigatus	60.66	0.00e+00	1307.00
IUUC-Ani-009412	Aspergillus nidulans	41.71	0.00e+00	1667.00
IUUC-Ang-009771	Aspergillus niger	42.71	0.00e+00	1738.00
IUUC-Aor-010186	Aspergillus oryzae	59.93	0.00e+00	1307.00
IUUC-Ate-010253	Aspergillus terreus	59.81	0.00e+00	1320.00
IUUC-Ame-011067	Astyanax mexicanus	51.25	3.00e-132	466.00
IUUC-Bgr-012043	Blumeria graminis	39.58	0.00e+00	1492.00
IUUC-Bta-012813	Bos taurus	52.41	3.00e-133	470.00
IUUC-Bci-013995	Botrytis cinerea	57.96	0.00e+00	1226.00
IUUC-Bdi-014884	Brachypodium distachyon	34.45	5.00e-139	488.00
IUUC-Bol-016533	Brassica oleracea	53.45	3.00e-89	319.00
IUUC-Bra-016726	Brassica rapa	39.35	2.00e-136	480.00
IUUC-Cel-018179	Caenorhabditis elegans	49.18	1.00e-125	444.00
IUUC-Cja-018741	Callithrix jacchus	52.29	2.00e-132	466.00
IUUC-Cfa-020083	Canis familiaris	52.41	3.00e-133	470.00
IUUC-Cpo-021923	Cavia porcellus	43.18	7.00e-96	345.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	48.71	6.00e-124	435.00
IUUC-Csa-023853	Chlorocebus sabaeus	52.41	2.00e-133	470.00
IUUC-Cho-024718	Choloepus hoffmanni	55.71	1.00e-121	431.00
IUUC-Cin-025627	Ciona intestinalis	51.53	5.00e-131	462.00
IUUC-Csv-025872	Ciona savignyi	51.88	2.00e-128	450.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	35.43	0.00e+00	1207.00
IUUC-Cne-027095	Cryptococcus neoformans	35.94	0.00e+00	644.00
IUUC-Cme-027267	Cyanidioschyzon merolae	49.64	6.00e-117	414.00
IUUC-Dre-028525	Danio rerio	50.61	8.00e-120	425.00
IUUC-Dno-029680	Dasypus novemcinctus	52.41	2.00e-133	470.00
IUUC-Dor-030902	Dipodomys ordii	47.00	2.00e-111	397.00
IUUC-Dse-031197	Dothistroma septosporum	38.83	0.00e+00	1410.00
IUUC-Dme-032122	Drosophila melanogaster	52.36	3.00e-131	463.00
IUUC-Ete-032966	Echinops telfairi	41.19	4.00e-96	344.00
IUUC-Eca-033915	Equus caballus	51.38	7.00e-131	462.00
IUUC-Eeu-034963	Erinaceus europaeus	52.06	3.00e-131	463.00
IUUC-Fca-035824	Felis catus	52.41	2.00e-133	470.00
IUUC-Fal-036687	Ficedula albicollis	39.60	8.00e-95	340.00
IUUC-Fox-037756	Fusarium oxysporum	56.04	0.00e+00	1236.00
IUUC-Fso-038464	Fusarium solani	55.31	0.00e+00	1214.00
IUUC-Gmo-039073	Gadus morhua	51.24	3.00e-132	466.00
IUUC-Ggr-039946	Gaeumannomyces graminis	56.05	0.00e+00	1191.00
IUUC-Gga-040309	Gallus gallus	56.21	7.00e-104	368.00
IUUC-Gac-042430	Gasterosteus aculeatus	51.24	3.00e-132	466.00
IUUC-Gma-044216	Glycine max	32.75	7.00e-150	525.00
IUUC-Ggo-044465	Gorilla gorilla	40.73	2.00e-95	342.00
IUUC-Hsa-046879	Homo sapiens	52.41	2.00e-133	470.00
IUUC-Hvu-047697	Hordeum vulgare	32.33	6.00e-139	488.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	52.41	2.00e-133	469.00
IUUC-Kpa-049228	Komagataella pastoris	58.49	0.00e+00	746.00
IUUC-Lch-050252	Latimeria chalumnae	52.06	6.00e-132	465.00
IUUC-Lpe-051550	Leersia perrieri	32.42	9.00e-140	491.00
IUUC-Loc-052472	Lepisosteus oculatus	52.08	4.00e-133	469.00
IUUC-Lma-053159	Leptosphaeria maculans	78.35	0.00e+00	3440.00
IUUC-Laf-054154	Loxodonta africana	52.41	2.00e-133	470.00
IUUC-Mcc-055085	Macaca mulatta	52.41	3.00e-133	469.00
IUUC-Mor-057201	Magnaporthe oryzae	56.14	0.00e+00	1190.00
IUUC-Mpo-057597	Magnaporthe poae	69.06	0.00e+00	942.00
IUUC-Mtr-057633	Medicago truncatula	33.06	3.00e-152	532.00
IUUC-Mla-058888	Melampsora laricipopulina	54.55	2.00e-136	477.00
IUUC-Mga-059935	Meleagris gallopavo	40.13	6.00e-95	340.00
IUUC-Mvi-060320	Microbotryum violaceum	45.03	0.00e+00	737.00
IUUC-Mmr-060820	Microcebus murinus	52.41	2.00e-133	470.00
IUUC-Mdo-062930	Monodelphis domestica	52.64	4.00e-134	473.00
IUUC-Mmu-063601	Mus musculus	52.41	2.00e-133	470.00
IUUC-Mac-065229	Musa acuminata	33.61	9.00e-152	531.00
IUUC-Mpu-066653	Mustela putorius furo	52.41	2.00e-133	470.00
IUUC-Mlu-067418	Myotis lucifugus	52.41	2.00e-133	470.00
IUUC-Nfi-068278	Neosartorya fischeri	60.09	0.00e+00	1312.00
IUUC-Ncr-068813	Neurospora crassa	34.05	0.00e+00	1123.00
IUUC-Nle-069418	Nomascus leucogenys	52.41	2.00e-133	470.00
IUUC-Ont-071300	Oreochromis niloticus	51.24	6.00e-132	465.00
IUUC-Oan-073046	Ornithorhynchus anatinus	52.63	3.00e-133	469.00
IUUC-Ocu-074178	Oryctolagus cuniculus	52.41	1.00e-133	471.00
IUUC-Oba-075757	Oryza barthii	32.91	2.00e-144	507.00
IUUC-Obr-076553	Oryza brachyantha	32.77	6.00e-141	495.00
IUUC-Ogl-077520	Oryza glaberrima	32.91	9.00e-145	508.00
IUUC-Ogu-078278	Oryza glumaepatula	32.79	9.00e-142	498.00
IUUC-Oin-079767	Oryza indica	32.91	4.00e-145	509.00
IUUC-Olo-080380	Oryza longistaminata	32.68	4.00e-140	492.00
IUUC-Ome-081925	Oryza meridionalis	32.80	3.00e-143	502.00
IUUC-Oni-082619	Oryza nivara	32.97	7.00e-145	508.00
IUUC-Opu-083684	Oryza punctata	32.80	6.00e-142	498.00
IUUC-Oru-084501	Oryza rufipogon	32.91	4.00e-145	509.00
IUUC-Osa-086251	Oryza sativa	35.41	2.00e-136	478.00
IUUC-Ola-086777	Oryzias latipes	39.82	6.00e-96	343.00
IUUC-Olu-087813	Ostreococcus lucimarinus	46.68	1.00e-112	397.00
IUUC-Oga-088903	Otolemur garnettii	52.41	2.00e-133	470.00
IUUC-Oar-090210	Ovis aries	52.41	3.00e-133	469.00
IUUC-Ptr-090529	Pan troglodytes	40.96	3.00e-95	341.00
IUUC-Pan-092368	Papio anubis	52.12	2.00e-121	430.00
IUUC-Psi-093969	Pelodiscus sinensis	40.58	3.00e-96	344.00
IUUC-Pno-094871	Phaeosphaeria nodorum	71.97	0.00e+00	3240.00
IUUC-Ppa-095834	Physcomitrella patens	35.40	5.00e-136	479.00
IUUC-Pfo-096232	Poecilia formosa	51.24	2.00e-132	467.00
IUUC-Pab-098583	Pongo abelii	52.41	3.00e-133	469.00
IUUC-Pop-099468	Populus trichocarpa	32.80	4.00e-150	525.00
IUUC-Pca-100310	Procavia capensis	56.85	1.00e-84	308.00
IUUC-Ppe-101641	Prunus persica	32.61	2.00e-149	523.00
IUUC-Pva-102116	Pteropus vampyrus	49.66	8.00e-121	428.00
IUUC-Pgr-103465	Puccinia graminis	46.46	3.00e-174	606.00
IUUC-Ptt-103813	Puccinia triticina	40.21	0.00e+00	724.00
IUUC-Pte-104018	Pyrenophora teres	94.73	0.00e+00	4292.00
IUUC-Rno-105153	Rattus norvegicus	40.96	1.00e-95	343.00
IUUC-Sce-106449	Saccharomyces cerevisiae	52.53	0.00e+00	694.00
IUUC-Sha-106961	Sarcophilus harrisii	52.64	6.00e-134	472.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	45.26	0.00e+00	862.00
IUUC-Spo-108024	Schizosaccharomyces pombe	44.36	0.00e+00	843.00
IUUC-Smo-109428	Selaginella moellendorffii	35.72	1.00e-136	480.00
IUUC-Sit-110598	Setaria italica	33.53	1.00e-141	498.00
IUUC-Sly-111706	Solanum lycopersicum	39.56	2.00e-139	490.00
IUUC-Stu-112894	Solanum tuberosum	30.28	2.00e-53	202.00
IUUC-Sar-113291	Sorex araneus	53.12	8.00e-129	455.00
IUUC-Sbi-114042	Sorghum bicolor	33.56	4.00e-146	512.00
IUUC-Sre-114958	Sporisorium reilianum	55.53	2.00e-175	607.00
IUUC-Ssc-115754	Sus scrofa	52.41	3.00e-133	470.00
IUUC-Tgu-117225	Taeniopygia guttata	39.82	6.00e-95	340.00
IUUC-Tru-118570	Takifugu rubripes	51.24	2.00e-132	466.00
IUUC-Tsy-119407	Tarsius syrichta	43.44	5.00e-91	327.00
IUUC-Tni-120836	Tetraodon nigroviridis	49.66	1.00e-126	447.00
IUUC-Tca-121479	Theobroma cacao	33.72	4.00e-150	525.00
IUUC-Tre-121909	Trichoderma reesei	36.40	0.00e+00	1229.00
IUUC-Tvi-122370	Trichoderma virens	35.38	0.00e+00	1183.00
IUUC-Tae-125214	Triticum aestivum	32.65	1.00e-135	476.00
IUUC-Tur-126774	Triticum urartu	32.20	8.00e-52	196.00
IUUC-Tme-127172	Tuber melanosporum	37.98	0.00e+00	1428.00
IUUC-Ttr-129253	Tursiops truncatus	52.41	5.00e-133	469.00
IUUC-Uma-129355	Ustilago maydis	57.20	2.00e-176	610.00
IUUC-Vda-129886	Verticillium dahliae	53.44	0.00e+00	1154.00
IUUC-Vpa-130708	Vicugna pacos	52.41	6.00e-133	469.00
IUUC-Vvi-131078	Vitis vinifera	44.05	2.00e-136	480.00
IUUC-Xtr-132123	Xenopus tropicalis	49.66	4.00e-124	439.00
IUUC-Xma-133869	Xiphophorus maculatus	51.24	1.00e-132	467.00
IUUC-Yli-134657	Yarrowia lipolytica	45.71	0.00e+00	942.00
IUUC-Zma-135581	Zea mays	32.77	3.00e-139	489.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence