iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	14747994

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity).

Protein Sequence
(Fasta)

MNQSDSSLMD LPLEIHLSLL EYVPNELRAV NKYFYVLHNH SYKEKSLAWI AEDNYIWAVV 60
KHSLCLYVKS LDPLRQHARE IIQETKEPGF NVPLCMTKYI ADSWYIVYNA LQYPGKIINM 120

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Nucleotide Sequence
(Fasta)

ATGAATCAGA GCGATAGCAG CTTGATGGAT TTACCACTGG AGATACATTT ATCATTACTA 60
GAGTACGTGC CTAATGAACT TCGTGCTGTC AATAAATACT TCTACGTTTT GCATAACCAC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0030674--F:protein binding, bridging
GO:0071406--P:cellular response to methylmercury
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

sce:YLR224W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007812	Ashbya gossypii	28.57	5.00e-04	36.60
IUUC-Afl-008680	Aspergillus flavus	25.00	5.50e-01	27.70
IUUC-Ani-009362	Aspergillus nidulans	34.15	1.00e-01	30.40
IUUC-Aor-009880	Aspergillus oryzae	24.17	5.80e-01	27.70
IUUC-Ate-010311	Aspergillus terreus	36.84	2.30e-02	29.60
IUUC-Ame-011788	Astyanax mexicanus	27.27	9.00e-03	33.10
IUUC-Cel-018341	Caenorhabditis elegans	26.67	3.90e-02	30.80
IUUC-Cgl-026478	Colletotrichum gloeosporioides	31.03	7.30e-02	30.00
IUUC-Kpa-049361	Komagataella pastoris	37.04	1.00e-06	45.80
IUUC-Lch-050651	Latimeria chalumnae	29.58	9.00e-03	33.10
IUUC-Mpo-057477	Magnaporthe poae	36.59	1.70e+00	26.20
IUUC-Mla-059109	Melampsora laricipopulina	27.94	1.50e-02	30.00
IUUC-Mac-065665	Musa acuminata	32.08	1.10e-02	33.50
IUUC-Nfi-068297	Neosartorya fischeri	30.91	2.20e-01	29.30
IUUC-Ncr-068666	Neurospora crassa	39.22	5.00e-03	32.30
IUUC-Opr-071226	Ochotona princeps	29.49	9.60e-02	30.00
IUUC-Ogl-076927	Oryza glaberrima	32.56	7.70e-02	29.60
IUUC-Ppa-095344	Physcomitrella patens	40.54	1.50e-01	29.60
IUUC-Pop-098884	Populus trichocarpa	26.92	3.90e-02	30.80
IUUC-Pca-100231	Procavia capensis	32.79	3.90e-02	30.80
IUUC-Ppe-101718	Prunus persica	29.85	1.30e-02	33.10
IUUC-Pte-104141	Pyrenophora teres	21.85	5.00e-02	30.00
IUUC-Rno-105240	Rattus norvegicus	28.92	5.00e-02	30.00
IUUC-Smo-109185	Selaginella moellendorffii	33.90	4.70e-02	30.80
IUUC-Sbi-113985	Sorghum bicolor	33.33	1.60e-02	31.60
IUUC-Ssc-115366	Sus scrofa	37.04	1.20e+00	26.20
IUUC-Tsy-119162	Tarsius syrichta	40.00	1.50e+00	25.00
IUUC-Tca-121332	Theobroma cacao	46.15	4.40e-01	27.70
IUUC-Tvi-122556	Trichoderma virens	30.77	1.00e-04	38.90
IUUC-Tae-123977	Triticum aestivum	30.56	5.00e-03	33.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence