iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068555

Ensembl Protein ID

CADNFIAP00002395

UniProt Accession

A1DCU5; DDI1_NEOFI

Genbank Protein ID

EAW19655.1

Protein Name

DNA damage-inducible protein 1

Genbank Nucleotide ID

DS027695

Gene Name

NFIA_027290; ddi1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00002467	CADNFIAT00002467	CADNFIAP00002395

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	8.60e-07	28.0	370	401
ULD/UDP/UBQ/UBQ_Other	7.50e-08	31.3	1	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraannnleaAv 35
           +d +++++e GF+reea++aL aan++l+ A+
   Q: 370  QDSIAKITELGFTREEAVRALDAANGDLDGAI 401
           789**************************998 PP

ULD/UDP/UBQ/UBQ_Other

   S: 21   dtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekk 73
           +tV  LK  +e++++ip + qrL+y +++L  d +tL + g+ +g+ + + +++
   Q: 1    MTVELLKAIVESETSIPTNNQRLVYNNQLLgNDAQTLEQIGIGEGDMLGVHVTM 54
           69999****************************************988777766 PP

Organism

Neosartorya fischeri

Functional Description
(View)

Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity).

Protein Sequence
(Fasta)

MTVELLKAIV ESETSIPTNN QRLVYNNQLL GNDAQTLEQI GIGEGDMLGV HVTMRSPQAP 60
ARSIGGGPSA AAQQNLQRRQ PMTPDPETIR LHILGDPRVR EAVRRQNPEL ADAANDAQRF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGTCG AGCTTCTCAA GGCTATCGTT GAGAGCGAAA CATCCATACC CACAAATAAT 60
CAGCGCCTTG TATATAACAA CCAACTACTT GGAAATGATG CGCAGACTTT GGAGCAGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR033322--DDI1
IPR019103--Peptidase_aspartic_DDI1-type
IPR021109--Peptidase_aspartic_dom
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF09668--Asp_protease
PF00627--UBA
PF00240--ubiquitin

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004190--F:aspartic-type endopeptidase activity
GO:0015031--P:protein transport

KEGG

nfi:NFIA_027290

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000989	Aegilops tauschii	36.59	7.00e-71	259.00
IUUC-Aml-001440	Ailuropoda melanoleuca	41.72	3.00e-62	230.00
IUUC-Atr-002722	Amborella trichopoda	37.90	2.00e-65	241.00
IUUC-Apl-003902	Anas platyrhynchos	53.73	2.00e-52	197.00
IUUC-Aca-004811	Anolis carolinensis	52.17	8.00e-60	222.00
IUUC-Aly-006104	Arabidopsis lyrata	33.61	1.00e-17	81.30
IUUC-Ath-007673	Arabidopsis thaliana	39.13	3.00e-75	273.00
IUUC-Ago-007981	Ashbya gossypii	38.31	3.00e-59	220.00
IUUC-Acl-008073	Aspergillus clavatus	91.85	0.00e+00	654.00
IUUC-Afl-008728	Aspergillus flavus	86.91	0.00e+00	672.00
IUUC-Afu-008934	Aspergillus fumigatus	99.26	0.00e+00	731.00
IUUC-Ani-009436	Aspergillus nidulans	76.56	4.00e-175	605.00
IUUC-Ang-009596	Aspergillus niger	85.80	1.00e-134	470.00
IUUC-Aor-009968	Aspergillus oryzae	86.91	0.00e+00	673.00
IUUC-Ate-010376	Aspergillus terreus	85.23	2.00e-175	607.00
IUUC-Ame-011570	Astyanax mexicanus	54.59	1.00e-64	238.00
IUUC-Bgr-012020	Blumeria graminis	50.49	2.00e-102	363.00
IUUC-Bta-012334	Bos taurus	41.92	2.00e-63	234.00
IUUC-Bci-013907	Botrytis cinerea	53.53	1.00e-107	381.00
IUUC-Bdi-014595	Brachypodium distachyon	37.53	5.00e-73	266.00
IUUC-Bol-015258	Brassica oleracea	38.29	6.00e-72	262.00
IUUC-Bra-016740	Brassica rapa	38.52	1.00e-70	258.00
IUUC-Cel-018415	Caenorhabditis elegans	39.29	2.00e-30	124.00
IUUC-Cja-018968	Callithrix jacchus	41.02	7.00e-61	226.00
IUUC-Cfa-020530	Canis familiaris	42.01	4.00e-62	230.00
IUUC-Cpo-022103	Cavia porcellus	52.19	4.00e-51	193.00
IUUC-Cre-022841	Chlamydomonas reinhardtii	37.80	1.00e-50	192.00
IUUC-Csa-023591	Chlorocebus sabaeus	41.62	6.00e-62	231.00
IUUC-Cho-024777	Choloepus hoffmanni	31.38	6.00e-34	136.00
IUUC-Cin-025396	Ciona intestinalis	34.78	3.00e-25	106.00
IUUC-Csv-026270	Ciona savignyi	37.16	2.00e-64	237.00
IUUC-Cgl-026570	Colletotrichum gloeosporioides	53.77	1.00e-85	308.00
IUUC-Cne-026974	Cryptococcus neoformans	42.07	2.00e-80	291.00
IUUC-Cme-027324	Cyanidioschyzon merolae	44.85	2.00e-37	147.00
IUUC-Dre-028030	Danio rerio	40.69	4.00e-62	230.00
IUUC-Dno-029264	Dasypus novemcinctus	41.79	1.00e-62	231.00
IUUC-Dor-030621	Dipodomys ordii	50.79	1.00e-12	65.90
IUUC-Dse-031180	Dothistroma septosporum	34.80	2.00e-23	101.00
IUUC-Dme-032067	Drosophila melanogaster	33.04	3.00e-61	227.00
IUUC-Ete-032664	Echinops telfairi	40.91	2.00e-46	177.00
IUUC-Eca-034133	Equus caballus	38.97	4.00e-42	163.00
IUUC-Eeu-035148	Erinaceus europaeus	42.23	3.00e-46	177.00
IUUC-Fca-035376	Felis catus	41.84	1.00e-61	228.00
IUUC-Fal-037210	Ficedula albicollis	23.39	3.00e-07	47.40
IUUC-Fox-037786	Fusarium oxysporum	47.52	1.00e-95	341.00
IUUC-Gmo-039324	Gadus morhua	44.20	9.00e-63	232.00
IUUC-Ggr-039750	Gaeumannomyces graminis	47.48	6.00e-91	326.00
IUUC-Gga-040917	Gallus gallus	59.81	1.00e-31	127.00
IUUC-Gac-041785	Gasterosteus aculeatus	53.85	5.00e-65	239.00
IUUC-Gma-043134	Glycine max	36.76	9.00e-67	245.00
IUUC-Ggo-044472	Gorilla gorilla	41.35	8.00e-49	185.00
IUUC-Hsa-046783	Homo sapiens	41.32	1.00e-62	231.00
IUUC-Hvu-047222	Hordeum vulgare	37.07	6.00e-69	252.00
IUUC-Itr-048836	Ictidomys tridecemlineatus	51.74	6.00e-59	219.00
IUUC-Kpa-049208	Komagataella pastoris	35.52	5.00e-61	226.00
IUUC-Lch-049953	Latimeria chalumnae	53.48	4.00e-59	221.00
IUUC-Lpe-050925	Leersia perrieri	36.34	1.00e-64	238.00
IUUC-Loc-052009	Lepisosteus oculatus	38.69	1.00e-62	232.00
IUUC-Lma-053305	Leptosphaeria maculans	48.58	7.00e-81	292.00
IUUC-Laf-054347	Loxodonta africana	41.59	1.00e-55	208.00
IUUC-Mcc-054796	Macaca mulatta	41.92	2.00e-62	232.00
IUUC-Meu-055944	Macropus eugenii	34.94	2.00e-43	168.00
IUUC-Mpo-057402	Magnaporthe poae	47.10	4.00e-93	333.00
IUUC-Mtr-058181	Medicago truncatula	31.25	1.00e-04	38.10
IUUC-Mla-058983	Melampsora laricipopulina	38.42	8.00e-22	95.10
IUUC-Mga-059910	Meleagris gallopavo	41.54	2.00e-57	214.00
IUUC-Mvi-060225	Microbotryum violaceum	57.26	5.00e-76	276.00
IUUC-Mmr-061679	Microcebus murinus	42.34	2.00e-53	201.00
IUUC-Mdo-062992	Monodelphis domestica	41.14	7.00e-63	232.00
IUUC-Mmu-063187	Mus musculus	41.92	2.00e-62	231.00
IUUC-Mac-064640	Musa acuminata	36.67	4.00e-68	249.00
IUUC-Mpu-066770	Mustela putorius furo	44.48	3.00e-52	197.00
IUUC-Mlu-067804	Myotis lucifugus	43.44	4.00e-60	223.00
IUUC-Ncr-068839	Neurospora crassa	49.77	2.00e-102	363.00
IUUC-Nle-069089	Nomascus leucogenys	41.92	2.00e-62	232.00
IUUC-Opr-070199	Ochotona princeps	40.47	2.00e-56	211.00
IUUC-Ont-072300	Oreochromis niloticus	43.90	9.00e-66	242.00
IUUC-Oan-073421	Ornithorhynchus anatinus	52.17	1.00e-59	221.00
IUUC-Ocu-074510	Oryctolagus cuniculus	41.40	6.00e-54	202.00
IUUC-Oba-075183	Oryza barthii	37.96	3.00e-70	256.00
IUUC-Obr-076044	Oryza brachyantha	38.14	3.00e-70	256.00
IUUC-Ogl-077284	Oryza glaberrima	37.71	2.00e-67	248.00
IUUC-Ogu-078171	Oryza glumaepatula	37.71	2.00e-67	247.00
IUUC-Oin-079871	Oryza indica	37.47	8.00e-70	255.00
IUUC-Olo-080579	Oryza longistaminata	37.71	9.00e-71	258.00
IUUC-Ome-081972	Oryza meridionalis	37.71	5.00e-71	259.00
IUUC-Oni-083027	Oryza nivara	37.71	2.00e-67	248.00
IUUC-Opu-083491	Oryza punctata	37.56	5.00e-67	246.00
IUUC-Oru-084589	Oryza rufipogon	37.71	2.00e-67	248.00
IUUC-Osa-085703	Oryza sativa	37.71	2.00e-67	248.00
IUUC-Ola-086911	Oryzias latipes	49.19	4.00e-26	109.00
IUUC-Olu-087654	Ostreococcus lucimarinus	41.64	7.00e-59	219.00
IUUC-Oga-089146	Otolemur garnettii	40.29	3.00e-43	167.00
IUUC-Oar-089924	Ovis aries	41.92	2.00e-63	234.00
IUUC-Ptr-090938	Pan troglodytes	41.32	1.00e-62	231.00
IUUC-Pan-091767	Papio anubis	41.32	2.00e-62	231.00
IUUC-Psi-093426	Pelodiscus sinensis	40.12	3.00e-60	224.00
IUUC-Pno-094977	Phaeosphaeria nodorum	42.99	6.00e-89	319.00
IUUC-Ppa-095744	Physcomitrella patens	34.94	6.00e-62	229.00
IUUC-Pfo-097404	Poecilia formosa	53.04	1.00e-58	218.00
IUUC-Pab-098128	Pongo abelii	41.32	1.00e-62	231.00
IUUC-Pop-099053	Populus trichocarpa	36.45	3.00e-65	240.00
IUUC-Pca-100554	Procavia capensis	40.00	3.00e-47	180.00
IUUC-Ppe-101690	Prunus persica	36.03	1.00e-65	242.00
IUUC-Pva-102638	Pteropus vampyrus	33.33	1.00e-37	148.00
IUUC-Pgr-103310	Puccinia graminis	69.57	2.00e-13	66.60
IUUC-Ptt-103798	Puccinia triticina	57.52	7.00e-71	259.00
IUUC-Pte-104408	Pyrenophora teres	50.30	5.00e-88	316.00
IUUC-Pyt-104420	Pyrenophora triticirepentis	44.06	3.00e-90	323.00
IUUC-Rno-105333	Rattus norvegicus	41.92	4.00e-62	231.00
IUUC-Sce-106167	Saccharomyces cerevisiae	32.86	4.00e-57	213.00
IUUC-Sha-107599	Sarcophilus harrisii	52.17	1.00e-59	221.00
IUUC-Sja-107968	Schizosaccharomyces japonicus	45.81	9.00e-58	215.00
IUUC-Spo-108130	Schizosaccharomyces pombe	44.91	3.00e-72	263.00
IUUC-Ssl-108671	Sclerotinia sclerotiorum	54.07	5.00e-110	389.00
IUUC-Sit-109819	Setaria italica	36.67	2.00e-71	261.00
IUUC-Sly-110983	Solanum lycopersicum	38.39	7.00e-67	245.00
IUUC-Stu-112218	Solanum tuberosum	37.01	2.00e-68	251.00
IUUC-Sar-113702	Sorex araneus	25.98	1.00e-06	44.30
IUUC-Sbi-114118	Sorghum bicolor	36.83	1.00e-69	255.00
IUUC-Sre-115084	Sporisorium reilianum	46.69	3.00e-66	244.00
IUUC-Ssc-115545	Sus scrofa	43.11	1.00e-62	231.00
IUUC-Tgu-117353	Taeniopygia guttata	41.14	2.00e-58	218.00
IUUC-Tru-117838	Takifugu rubripes	54.78	3.00e-65	240.00
IUUC-Tsy-118783	Tarsius syrichta	52.73	5.00e-41	159.00
IUUC-Tni-120287	Tetraodon nigroviridis	43.73	7.00e-68	249.00
IUUC-Tca-121513	Theobroma cacao	36.03	4.00e-63	233.00
IUUC-Tvi-122402	Trichoderma virens	48.37	1.00e-26	112.00
IUUC-Tae-125471	Triticum aestivum	37.41	1.00e-71	261.00
IUUC-Tur-126159	Triticum urartu	37.16	6.00e-64	236.00
IUUC-Tme-127088	Tuber melanosporum	50.97	3.00e-110	390.00
IUUC-Tbe-127948	Tupaia belangeri	39.31	1.00e-51	194.00
IUUC-Ttr-128560	Tursiops truncatus	41.62	4.00e-63	233.00
IUUC-Uma-129478	Ustilago maydis	55.79	9.00e-62	229.00
IUUC-Vda-129758	Verticillium dahliae	47.73	2.00e-80	290.00
IUUC-Vpa-130132	Vicugna pacos	61.07	3.00e-49	187.00
IUUC-Vvi-131006	Vitis vinifera	34.80	3.00e-61	227.00
IUUC-Xtr-132758	Xenopus tropicalis	50.87	1.00e-58	218.00
IUUC-Xma-133125	Xiphophorus maculatus	52.81	2.00e-57	214.00
IUUC-Yli-134530	Yarrowia lipolytica	34.06	4.00e-61	226.00
IUUC-Zma-135856	Zea mays	35.59	8.00e-68	248.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence