iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001426

Ensembl Protein ID

ENSAMEP00000007571.1

UniProt Accession

G1LKV1; G1LKV1_AILME

Genbank Protein ID

ENSAMEP00000007571

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01018339

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000007168.1	ENSAMET00000007889.1	ENSAMEP00000007571.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	92.25	0.00e+00	737.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

SGIMDRSKEN CIAGPLKTTV GLGDGPKRVL VTQQIPSQNP LSANSGQAQR VLCPSNSSQR 60
VPPQAQKLVS SHKPVQNLKQ KQLQATSVPR PVSRPLNNTQ KNEQASSSAP GNNSEKELAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGCATCA TGGACAGATC TAAAGAAAAC TGCATTGCAG GGCCTCTTAA GGTAAATTGA 60
ATATGTAATC TCGATCACAT TTATAAAATC CAATGGAGAT TGGTTTTATA TCTGGAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.03	3.00e-103	367.00
IUUC-Atr-002453	Amborella trichopoda	63.54	2.00e-106	378.00
IUUC-Apl-003626	Anas platyrhynchos	70.95	1.00e-154	538.00
IUUC-Aca-004602	Anolis carolinensis	66.75	2.00e-147	514.00
IUUC-Aly-005878	Arabidopsis lyrata	65.17	2.00e-104	371.00
IUUC-Ath-007117	Arabidopsis thaliana	65.92	7.00e-105	373.00
IUUC-Acl-008199	Aspergillus clavatus	57.30	1.00e-86	313.00
IUUC-Afl-008419	Aspergillus flavus	52.27	9.00e-87	313.00
IUUC-Afu-008751	Aspergillus fumigatus	52.12	1.00e-87	316.00
IUUC-Ani-009181	Aspergillus nidulans	52.61	1.00e-90	326.00
IUUC-Ang-009787	Aspergillus niger	51.79	1.00e-87	316.00
IUUC-Aor-009980	Aspergillus oryzae	52.27	9.00e-87	313.00
IUUC-Ate-010286	Aspergillus terreus	52.24	1.00e-86	313.00
IUUC-Ame-010849	Astyanax mexicanus	58.48	7.00e-128	450.00
IUUC-Bgr-012110	Blumeria graminis	60.31	3.00e-87	315.00
IUUC-Bta-013474	Bos taurus	90.44	0.00e+00	722.00
IUUC-Bci-013756	Botrytis cinerea	61.15	2.00e-93	335.00
IUUC-Bdi-014257	Brachypodium distachyon	63.73	1.00e-104	372.00
IUUC-Bol-016310	Brassica oleracea	62.41	2.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	63.60	2.00e-103	368.00
IUUC-Cel-018157	Caenorhabditis elegans	63.26	7.00e-102	363.00
IUUC-Cja-019282	Callithrix jacchus	90.70	0.00e+00	706.00
IUUC-Cfa-020162	Canis familiaris	95.90	0.00e+00	783.00
IUUC-Cpo-021764	Cavia porcellus	84.32	0.00e+00	649.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	67.42	9.00e-107	379.00
IUUC-Csa-023694	Chlorocebus sabaeus	90.70	0.00e+00	658.00
IUUC-Cho-024350	Choloepus hoffmanni	97.45	1.00e-113	402.00
IUUC-Cin-025542	Ciona intestinalis	73.75	1.00e-117	416.00
IUUC-Csv-025873	Ciona savignyi	68.53	2.00e-118	418.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	50.65	1.00e-80	293.00
IUUC-Cne-026928	Cryptococcus neoformans	61.87	3.00e-95	342.00
IUUC-Cme-027336	Cyanidioschyzon merolae	73.00	2.00e-118	419.00
IUUC-Dre-028198	Danio rerio	62.03	1.00e-129	456.00
IUUC-Dno-029928	Dasypus novemcinctus	88.89	0.00e+00	670.00
IUUC-Dor-030238	Dipodomys ordii	79.33	9.00e-180	622.00
IUUC-Dse-031266	Dothistroma septosporum	60.46	4.00e-92	331.00
IUUC-Dme-032007	Drosophila melanogaster	61.69	1.00e-99	356.00
IUUC-Ete-032911	Echinops telfairi	69.29	9.00e-138	483.00
IUUC-Eca-033749	Equus caballus	94.57	0.00e+00	754.00
IUUC-Eeu-035170	Erinaceus europaeus	89.43	0.00e+00	711.00
IUUC-Fca-035498	Felis catus	95.71	0.00e+00	738.00
IUUC-Fal-037397	Ficedula albicollis	69.98	9.00e-149	519.00
IUUC-Fox-037747	Fusarium oxysporum	59.16	7.00e-90	323.00
IUUC-Fso-038429	Fusarium solani	55.56	8.00e-89	320.00
IUUC-Gmo-039378	Gadus morhua	60.32	8.00e-125	439.00
IUUC-Ggr-039939	Gaeumannomyces graminis	60.52	3.00e-94	338.00
IUUC-Gga-040187	Gallus gallus	71.74	3.00e-152	531.00
IUUC-Gac-042223	Gasterosteus aculeatus	62.08	6.00e-131	460.00
IUUC-Gma-042870	Glycine max	66.17	3.00e-98	351.00
IUUC-Ggo-045617	Gorilla gorilla	91.99	0.00e+00	736.00
IUUC-Hsa-046968	Homo sapiens	92.25	0.00e+00	737.00
IUUC-Hvu-047072	Hordeum vulgare	55.17	3.00e-80	291.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	78.04	2.00e-175	608.00
IUUC-Kpa-049093	Komagataella pastoris	56.70	1.00e-77	283.00
IUUC-Lch-050346	Latimeria chalumnae	69.54	1.00e-146	512.00
IUUC-Lpe-051466	Leersia perrieri	67.30	6.00e-105	373.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	6.00e-89	320.00
IUUC-Laf-053422	Loxodonta africana	89.15	0.00e+00	709.00
IUUC-Mcc-055245	Macaca mulatta	90.70	0.00e+00	657.00
IUUC-Mor-056952	Magnaporthe oryzae	58.78	2.00e-90	325.00
IUUC-Mpo-057605	Magnaporthe poae	59.71	5.00e-95	340.00
IUUC-Mtr-057726	Medicago truncatula	66.29	2.00e-104	371.00
IUUC-Mla-059174	Melampsora laricipopulina	63.71	5.00e-99	354.00
IUUC-Mga-059562	Meleagris gallopavo	61.96	1.00e-117	416.00
IUUC-Mvi-060305	Microbotryum violaceum	61.98	5.00e-94	338.00
IUUC-Mmr-061588	Microcebus murinus	88.60	0.00e+00	715.00
IUUC-Mdo-061914	Monodelphis domestica	79.34	7.00e-179	619.00
IUUC-Mmu-063288	Mus musculus	84.83	0.00e+00	659.00
IUUC-Mac-064969	Musa acuminata	64.44	3.00e-105	374.00
IUUC-Mpu-066855	Mustela putorius furo	96.38	0.00e+00	774.00
IUUC-Mlu-068046	Myotis lucifugus	90.77	0.00e+00	728.00
IUUC-Nfi-068527	Neosartorya fischeri	52.12	8.00e-87	313.00
IUUC-Ncr-068678	Neurospora crassa	60.84	2.00e-92	332.00
IUUC-Nle-069848	Nomascus leucogenys	91.73	0.00e+00	733.00
IUUC-Opr-070589	Ochotona princeps	82.38	0.00e+00	629.00
IUUC-Ont-071733	Oreochromis niloticus	62.67	3.00e-124	438.00
IUUC-Oan-073399	Ornithorhynchus anatinus	90.61	7.00e-151	526.00
IUUC-Ocu-074063	Oryctolagus cuniculus	87.56	0.00e+00	701.00
IUUC-Oba-075264	Oryza barthii	64.18	2.00e-104	371.00
IUUC-Obr-076048	Oryza brachyantha	66.04	1.00e-103	369.00
IUUC-Ogl-077637	Oryza glaberrima	66.92	8.00e-104	369.00
IUUC-Ogu-078830	Oryza glumaepatula	64.18	8.00e-105	372.00
IUUC-Oin-079150	Oryza indica	64.18	9.00e-105	372.00
IUUC-Olo-080398	Oryza longistaminata	57.68	2.00e-82	298.00
IUUC-Ome-081544	Oryza meridionalis	55.47	1.00e-89	322.00
IUUC-Oni-082250	Oryza nivara	64.18	9.00e-105	372.00
IUUC-Opu-083638	Oryza punctata	64.08	1.00e-104	372.00
IUUC-Oru-084981	Oryza rufipogon	64.18	7.00e-105	373.00
IUUC-Osa-085961	Oryza sativa	64.18	7.00e-105	373.00
IUUC-Olu-087880	Ostreococcus lucimarinus	70.11	3.00e-111	394.00
IUUC-Oga-088891	Otolemur garnettii	87.92	0.00e+00	709.00
IUUC-Oar-090021	Ovis aries	90.23	0.00e+00	702.00
IUUC-Ptr-091458	Pan troglodytes	92.51	0.00e+00	738.00
IUUC-Pan-092546	Papio anubis	90.18	0.00e+00	655.00
IUUC-Psi-093280	Pelodiscus sinensis	75.13	9.00e-165	572.00
IUUC-Pma-094298	Petromyzon marinus	77.86	9.00e-121	426.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.40	7.00e-89	320.00
IUUC-Ppa-095855	Physcomitrella patens	63.12	3.00e-107	381.00
IUUC-Pfo-096428	Poecilia formosa	62.15	3.00e-128	451.00
IUUC-Pab-098696	Pongo abelii	91.24	0.00e+00	715.00
IUUC-Pop-099405	Populus trichocarpa	61.49	1.00e-104	372.00
IUUC-Pca-100740	Procavia capensis	82.69	0.00e+00	658.00
IUUC-Ppe-101854	Prunus persica	66.17	5.00e-105	373.00
IUUC-Pva-103212	Pteropus vampyrus	91.21	0.00e+00	728.00
IUUC-Pgr-103474	Puccinia graminis	63.64	5.00e-99	354.00
IUUC-Ptt-103933	Puccinia triticina	49.81	1.00e-62	233.00
IUUC-Pte-104089	Pyrenophora teres	48.18	1.00e-89	323.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	48.18	1.00e-89	323.00
IUUC-Rno-105057	Rattus norvegicus	85.27	0.00e+00	663.00
IUUC-Sha-107137	Sarcophilus harrisii	81.47	0.00e+00	639.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	56.90	9.00e-100	356.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.85	2.00e-102	365.00
IUUC-Smo-109288	Selaginella moellendorffii	67.55	3.00e-107	381.00
IUUC-Sit-110246	Setaria italica	65.33	3.00e-104	371.00
IUUC-Sly-111379	Solanum lycopersicum	65.20	2.00e-105	375.00
IUUC-Stu-112777	Solanum tuberosum	65.91	3.00e-104	371.00
IUUC-Sbi-114325	Sorghum bicolor	64.96	3.00e-104	370.00
IUUC-Sre-115203	Sporisorium reilianum	59.55	8.00e-81	294.00
IUUC-Ssc-115361	Sus scrofa	91.47	0.00e+00	728.00
IUUC-Tgu-116967	Taeniopygia guttata	73.26	4.00e-150	523.00
IUUC-Tru-117570	Takifugu rubripes	63.05	2.00e-133	468.00
IUUC-Tsy-119280	Tarsius syrichta	66.15	4.00e-133	467.00
IUUC-Tni-120721	Tetraodon nigroviridis	64.72	9.00e-134	469.00
IUUC-Tca-121494	Theobroma cacao	65.79	5.00e-104	370.00
IUUC-Tre-121869	Trichoderma reesei	57.14	8.00e-94	337.00
IUUC-Tvi-122510	Trichoderma virens	61.22	2.00e-91	329.00
IUUC-Tae-123071	Triticum aestivum	63.03	3.00e-103	367.00
IUUC-Tur-126240	Triticum urartu	63.03	8.00e-103	366.00
IUUC-Tme-126921	Tuber melanosporum	63.32	6.00e-96	343.00
IUUC-Tbe-127872	Tupaia belangeri	83.69	2.00e-180	625.00
IUUC-Ttr-129134	Tursiops truncatus	91.47	0.00e+00	703.00
IUUC-Uma-129412	Ustilago maydis	58.65	1.00e-79	290.00
IUUC-Vda-130003	Verticillium dahliae	49.47	9.00e-92	330.00
IUUC-Vvi-131272	Vitis vinifera	62.24	2.00e-105	375.00
IUUC-Xtr-132019	Xenopus tropicalis	65.76	4.00e-149	521.00
IUUC-Xma-134203	Xiphophorus maculatus	61.46	7.00e-133	466.00
IUUC-Yli-134503	Yarrowia lipolytica	54.23	4.00e-86	311.00
IUUC-Zma-135232	Zea mays	65.20	4.00e-104	370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence