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Tag Content
UUCD2 ID IUUC-Mcc-055740
UUCD1 version UUC-MaM-00618
Ensembl Protein ID ENSMMUP00000046343.1
UniProt Accession G7NRH1; G7NRH1_MACMU
Genbank Protein ID AFE65713.1; AFH28816.1; AFI38440.1; EHH30749.1
Protein Name Lysine-specific demethylase 5C; Lysine-specific demethylase 5C isoform 1
Genbank Nucleotide ID JSUE03045588; JU472012; JV048369; CM001273
Gene Name KDM5C; EGK_20523
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000020553.3 ENSMMUT00000064448.1 ENSMMUP00000046343.1
ENSMMUG00000020553.3 ENSMMUT00000072753.1 ENSMMUP00000051741.1
ENSMMUG00000020553.3 ENSMMUT00000059616.1 ENSMMUP00000049144.1
ENSMMUG00000020553.3 ENSMMUT00000048011.2 ENSMMUP00000041052.2
ENSMMUG00000020553.3 ENSMMUT00000028923.3 ENSMMUP00000027068.3
ENSMMUG00000020553.3 ENSMMUT00000048012.2 ENSMMUP00000041053.2
ENSMMUG00000020553.3 ENSMMUT00000048010.2 ENSMMUP00000041051.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 5.80e-14 53.1 326 372
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vC +C +g+ed+ +l+ C+ C++++H  Cl ++  +e p+   w CpkC 
   Q: 326  VCRMCSRGDEDD-KLLLCDGCDDNYHIFCLLPP-LPEIPKGV-WRCPKCV 372
           8*********88.6*******************.*******8.******6 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MEPGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 60
DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERRIL DLYSLSKIVV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055740|E3,PHD|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCACCGCCGG TCCATCCGGA AAGAGGATCC GGCAAACTAA TTACAATCTT GTTCCTCCGC 60
CGTTGCAATG AACTATTTTC TCTCAATCGG GGGTGGTACT TTTGAGTAAC CCCTTCCGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055740|E3,PHD|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2
SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0003677--F:DNA binding
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0008168--F:methyltransferase activity
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated
KEGG mcc:106992262
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001327 Ailuropoda melanoleuca 97.61 0.00e+00 2669.00
IUUC-Aca-004712 Anolis carolinensis 79.94 0.00e+00 2013.00
IUUC-Afl-008625 Aspergillus flavus 30.32 2.00e-112 401.00
IUUC-Afu-008796 Aspergillus fumigatus 31.52 4.00e-116 413.00
IUUC-Aor-010155 Aspergillus oryzae 30.32 2.00e-112 401.00
IUUC-Bgr-012241 Blumeria graminis 29.61 2.00e-111 398.00
IUUC-Bta-013099 Bos taurus 96.07 0.00e+00 2613.00
IUUC-Bci-013992 Botrytis cinerea 30.51 1.00e-107 385.00
IUUC-Cja-018723 Callithrix jacchus 94.91 0.00e+00 2607.00
IUUC-Cfa-020954 Canis familiaris 97.98 0.00e+00 2605.00
IUUC-Cpo-021718 Cavia porcellus 97.96 0.00e+00 1370.00
IUUC-Csa-023946 Chlorocebus sabaeus 99.44 0.00e+00 2654.00
IUUC-Dre-028238 Danio rerio 63.39 0.00e+00 1866.00
IUUC-Dno-029435 Dasypus novemcinctus 94.61 0.00e+00 2615.00
IUUC-Dor-030226 Dipodomys ordii 90.68 0.00e+00 1805.00
IUUC-Dse-031479 Dothistroma septosporum 29.94 2.00e-119 425.00
IUUC-Eca-033834 Equus caballus 96.78 0.00e+00 2694.00
IUUC-Eeu-034692 Erinaceus europaeus 95.04 0.00e+00 2022.00
IUUC-Fca-035766 Felis catus 94.69 0.00e+00 2515.00
IUUC-Fox-037694 Fusarium oxysporum 32.40 9.00e-101 362.00
IUUC-Fso-038127 Fusarium solani 30.76 2.00e-116 414.00
IUUC-Gac-041825 Gasterosteus aculeatus 64.35 0.00e+00 1788.00
IUUC-Ggo-045492 Gorilla gorilla 99.36 0.00e+00 2751.00
IUUC-Hsa-046737 Homo sapiens 99.29 0.00e+00 2733.00
IUUC-Itr-048348 Ictidomys tridecemlineatus 97.61 0.00e+00 2757.00
IUUC-Lch-050517 Latimeria chalumnae 75.14 0.00e+00 2102.00
IUUC-Laf-054098 Loxodonta africana 88.85 0.00e+00 2375.00
IUUC-Meu-056643 Macropus eugenii 84.92 0.00e+00 2282.00
IUUC-Mtr-058113 Medicago truncatula 32.79 1.00e-97 352.00
IUUC-Mmr-061032 Microcebus murinus 98.38 0.00e+00 2638.00
IUUC-Mdo-062754 Monodelphis domestica 81.39 0.00e+00 2202.00
IUUC-Mmu-063943 Mus musculus 95.04 0.00e+00 2676.00
IUUC-Mpu-066800 Mustela putorius furo 96.84 0.00e+00 2669.00
IUUC-Mlu-067109 Myotis lucifugus 96.51 0.00e+00 2643.00
IUUC-Nfi-068430 Neosartorya fischeri 31.43 1.00e-113 405.00
IUUC-Ncr-068763 Neurospora crassa 28.54 4.00e-142 500.00
IUUC-Nle-069569 Nomascus leucogenys 99.42 0.00e+00 2619.00
IUUC-Ont-072274 Oreochromis niloticus 65.92 0.00e+00 1840.00
IUUC-Oan-073160 Ornithorhynchus anatinus 86.35 0.00e+00 2271.00
IUUC-Ocu-074440 Oryctolagus cuniculus 97.68 0.00e+00 2659.00
IUUC-Oin-079273 Oryza indica 37.84 1.00e-13 69.30
IUUC-Ola-087059 Oryzias latipes 66.05 0.00e+00 1873.00
IUUC-Oga-088191 Otolemur garnettii 97.34 0.00e+00 2697.00
IUUC-Oar-090027 Ovis aries 96.13 0.00e+00 2613.00
IUUC-Pan-091829 Papio anubis 99.68 0.00e+00 2751.00
IUUC-Pma-094137 Petromyzon marinus 52.18 0.00e+00 1379.00
IUUC-Pno-094879 Phaeosphaeria nodorum 29.79 2.00e-114 407.00
IUUC-Pfo-096645 Poecilia formosa 65.51 0.00e+00 1800.00
IUUC-Pab-097582 Pongo abelii 95.97 0.00e+00 2388.00
IUUC-Pca-100446 Procavia capensis 93.29 0.00e+00 2603.00
IUUC-Ppe-101504 Prunus persica 32.56 1.00e-103 372.00
IUUC-Pva-102553 Pteropus vampyrus 94.39 0.00e+00 1641.00
IUUC-Rno-105359 Rattus norvegicus 80.11 0.00e+00 2334.00
IUUC-Sha-106769 Sarcophilus harrisii 88.37 0.00e+00 2134.00
IUUC-Ssl-108489 Sclerotinia sclerotiorum 30.81 4.00e-119 423.00
IUUC-Sre-115161 Sporisorium reilianum 30.51 1.00e-133 472.00
IUUC-Ssc-116354 Sus scrofa 97.81 0.00e+00 2735.00
IUUC-Tru-117667 Takifugu rubripes 65.43 0.00e+00 1660.00
IUUC-Tni-119920 Tetraodon nigroviridis 64.55 0.00e+00 1793.00
IUUC-Tca-121478 Theobroma cacao 32.40 2.00e-106 381.00
IUUC-Tbe-128040 Tupaia belangeri 99.46 0.00e+00 1087.00
IUUC-Ttr-128979 Tursiops truncatus 97.49 0.00e+00 2685.00
IUUC-Vpa-130433 Vicugna pacos 99.47 0.00e+00 1811.00
IUUC-Vvi-131071 Vitis vinifera 32.27 4.00e-86 313.00
IUUC-Xtr-132324 Xenopus tropicalis 68.39 0.00e+00 1908.00
IUUC-Xma-134315 Xiphophorus maculatus 64.81 0.00e+00 1847.00
Created Date 25-Jun-2017

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