iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121660

Ensembl Protein ID

EOY13683

UniProt Accession

A0A061F9Z2; A0A061F9Z2_THECC

Genbank Protein ID

EOY13683.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase, putative isoform 2

Genbank Nucleotide ID

CM001885

Gene Name

TCM_032323

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_032323	EOY13682	EOY13682
TCM_032323	EOY13683	EOY13683

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-58	198.6	74	572

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflafl 99
           Gl+NlgN C++N +LQ+L++++ ++++l +  +k kl+  + ++++ +l+ +l+ l+eel    +++ a sp+++++al+ + ++f+ ++qqDa+E + +l
   Q: 74   GLQNLGNNCFLNVILQALASCSYFQSFLQKiLDKCKLSPVEGQDENLPLTITLTALLEELGmaGERRVALSPHKVMRALALYIQNFDLTSQQDAEEAFLHL 174
           9*************************999976666666666688999*************886888889******************************** PP
   S: 100  ldqleeelkk.....eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp.....gkeetkkeslqdc 190
           l +l+ee++      +++      ++++++  +++++++++++ ++     F+g + s ++c++c +++   +  +  slp+      g++ ++  +l+dc
   Q: 175  LTSLREEFSDiylpsQSTLADAFVSQTSRILIPQKEDQSEQERWQQHFLGPFDGIIGSILTCQSCSSQQICLDFQFFHSLPLLpvlygGSTIMAGCTLEDC 275
           ********77666422222222233334445566699999999999999********************888887777888775667777777777***** PP
   S: 191  Lesftkeeelegenkyycekck.............................................kkqeaekklklkklPevLilhLkRfsfseeqksr 246
           L++f+ +e++e+   yyc++c                                              + + + k+l++ ++P++L++hL+R s +e  +  
   Q: 276  LRQFVMAEQIEN---YYCSHCWhiaaikylsstganemeierlkrcsaqdscdcrsflclqklpwsnNFSCTLKQLSIARCPKILCIHLQRASINEF-GEL 372
           **********96...*******77777777777777777777766666666555555555555555444449*********************9998.777 PP
   S: 247  ekinkkvefpleLdlspfcts..............................................................peekqke........... 274
           +k++ +++fpl Ldlspf+ts                                                                    e           
   Q: 373  IKLQGHISFPLILDLSPFMTSeveikncggvqkgqvklqnqkpspclnlinlqfetifnhiskpmgevsseilaandfqctshG-----Esfpgksnlsqt 468
           9********************777777777777776666666666666666666666666666665555555555555555550.....055555555555 PP
   S: 275  .............................kkkYeLiavvvHsGslssGHYvayvkn...............ekgkWllfdDskVtevkeeevleetgstaY 331
                                        +k Y+L++vv H G +++GHY++y                   + +W++++Ds+V  v+e++vl    ++a 
   Q: 469  dgcskalntdmheqhgdkvsltsklppseTKLYQLVSVVEHFGRVGGGHYTVYRIMraksdeadsdeysepATMQWFCISDSQVCRVSEKDVLA---AEAS 566
           666666666666667777777778888879***********************9987777777776666655677*******************...**** PP
   S: 332  vlfYkr 337
           +lfY+r
   Q: 567  LLFYER 572
           ****98 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MMEMERDTSI RAIIRNWKHG CRALLHMRWA SAFGFHISVV GLVGVVGFVL AIIRDGKVGE 60
KRKKDLEKLC LVPGLQNLGN NCFLNVILQA LASCSYFQSF LQKILDKCKL SPVEGQDENL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAACCCA AAACCCCAAA GTCTCCGATT TGCTTATTGG TTCGCCCCTG GTGCAGTTTC 60
TTTTTACCTT CTTCATTTAG TAAGTTCCTC TTTATTAAAC TTTCCTTCAC CAATAAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	42.72	1.00e-59	223.00
IUUC-Aml-001733	Ailuropoda melanoleuca	24.30	8.00e-24	104.00
IUUC-Atr-002510	Amborella trichopoda	43.90	1.00e-103	369.00
IUUC-Apl-003645	Anas platyrhynchos	27.19	1.00e-13	69.30
IUUC-Aly-005754	Arabidopsis lyrata	55.56	2.00e-102	365.00
IUUC-Ath-007622	Arabidopsis thaliana	50.63	3.00e-104	371.00
IUUC-Ago-007761	Ashbya gossypii	25.19	2.00e-07	50.10
IUUC-Acl-008136	Aspergillus clavatus	22.84	3.00e-10	59.30
IUUC-Afl-008729	Aspergillus flavus	22.18	8.00e-14	71.60
IUUC-Aor-009965	Aspergillus oryzae	24.32	8.00e-17	81.30
IUUC-Ate-010591	Aspergillus terreus	25.07	1.00e-14	74.30
IUUC-Ame-010896	Astyanax mexicanus	27.19	3.00e-32	132.00
IUUC-Bgr-012133	Blumeria graminis	25.66	1.00e-09	57.80
IUUC-Bta-012321	Bos taurus	25.05	1.00e-28	120.00
IUUC-Bdi-014795	Brachypodium distachyon	40.90	7.00e-62	230.00
IUUC-Bol-015637	Brassica oleracea	52.10	9.00e-97	346.00
IUUC-Bra-016801	Brassica rapa	53.37	2.00e-97	348.00
IUUC-Cja-018826	Callithrix jacchus	24.62	3.00e-28	119.00
IUUC-Cfa-021206	Canis familiaris	25.56	2.00e-27	116.00
IUUC-Cpo-021343	Cavia porcellus	24.86	5.00e-27	115.00
IUUC-Csa-023419	Chlorocebus sabaeus	24.63	5.00e-28	118.00
IUUC-Cho-024475	Choloepus hoffmanni	24.35	5.00e-12	65.10
IUUC-Cne-027061	Cryptococcus neoformans	22.49	1.00e-11	64.70
IUUC-Dre-027563	Danio rerio	27.87	9.00e-33	134.00
IUUC-Dno-029929	Dasypus novemcinctus	25.56	6.00e-28	117.00
IUUC-Dor-030166	Dipodomys ordii	23.35	2.00e-22	99.80
IUUC-Ete-032634	Echinops telfairi	24.34	7.00e-17	81.30
IUUC-Eca-033968	Equus caballus	24.29	7.00e-26	110.00
IUUC-Fca-036525	Felis catus	25.79	8.00e-28	117.00
IUUC-Fal-036606	Ficedula albicollis	27.87	1.00e-18	86.30
IUUC-Gmo-038726	Gadus morhua	25.28	5.00e-27	114.00
IUUC-Gga-040718	Gallus gallus	26.15	6.00e-21	94.40
IUUC-Gac-042645	Gasterosteus aculeatus	28.06	2.00e-19	90.10
IUUC-Gma-042890	Glycine max	54.47	3.00e-142	497.00
IUUC-Ggo-045021	Gorilla gorilla	24.63	3.00e-28	119.00
IUUC-Hsa-045832	Homo sapiens	24.63	3.00e-28	119.00
IUUC-Hvu-047422	Hordeum vulgare	48.18	3.00e-28	115.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	23.92	1.00e-23	103.00
IUUC-Lch-050662	Latimeria chalumnae	29.19	2.00e-24	106.00
IUUC-Lpe-051078	Leersia perrieri	39.92	1.00e-92	332.00
IUUC-Loc-052611	Lepisosteus oculatus	25.66	1.00e-27	117.00
IUUC-Lma-053048	Leptosphaeria maculans	25.07	4.00e-11	62.80
IUUC-Laf-053752	Loxodonta africana	26.82	1.00e-20	93.60
IUUC-Mcc-054892	Macaca mulatta	24.63	3.00e-28	119.00
IUUC-Mor-057143	Magnaporthe oryzae	22.37	4.00e-11	62.80
IUUC-Mtr-057976	Medicago truncatula	50.68	3.00e-131	461.00
IUUC-Mla-058970	Melampsora laricipopulina	23.22	7.00e-13	68.20
IUUC-Mga-059543	Meleagris gallopavo	26.31	7.00e-27	114.00
IUUC-Mmr-061534	Microcebus murinus	25.23	1.00e-27	117.00
IUUC-Mmu-063673	Mus musculus	26.39	2.00e-19	90.10
IUUC-Mac-065451	Musa acuminata	48.69	3.00e-46	177.00
IUUC-Mpu-066328	Mustela putorius furo	25.75	8.00e-28	117.00
IUUC-Mlu-067938	Myotis lucifugus	25.23	1.00e-27	116.00
IUUC-Ncr-068741	Neurospora crassa	22.40	2.00e-11	63.90
IUUC-Nle-069426	Nomascus leucogenys	23.52	2.00e-21	95.90
IUUC-Opr-070796	Ochotona princeps	23.17	1.00e-12	67.00
IUUC-Ont-072248	Oreochromis niloticus	26.18	2.00e-26	112.00
IUUC-Oan-072916	Ornithorhynchus anatinus	25.80	9.00e-27	114.00
IUUC-Oba-075765	Oryza barthii	39.96	2.00e-92	332.00
IUUC-Obr-076005	Oryza brachyantha	42.23	2.00e-104	372.00
IUUC-Ogl-077916	Oryza glaberrima	41.65	2.00e-100	358.00
IUUC-Ogu-078263	Oryza glumaepatula	40.12	8.00e-93	333.00
IUUC-Oin-080096	Oryza indica	40.39	2.00e-73	269.00
IUUC-Olo-080702	Oryza longistaminata	36.99	7.00e-43	168.00
IUUC-Ome-081928	Oryza meridionalis	40.62	4.00e-95	341.00
IUUC-Oni-082424	Oryza nivara	40.15	7.00e-93	333.00
IUUC-Opu-083371	Oryza punctata	41.06	1.00e-94	340.00
IUUC-Oru-085117	Oryza rufipogon	40.15	7.00e-93	333.00
IUUC-Ola-087429	Oryzias latipes	26.60	2.00e-26	112.00
IUUC-Oga-087981	Otolemur garnettii	25.46	3.00e-27	115.00
IUUC-Oar-089927	Ovis aries	25.05	1.00e-28	120.00
IUUC-Ptr-090878	Pan troglodytes	24.63	3.00e-28	119.00
IUUC-Pan-092698	Papio anubis	24.63	3.00e-28	119.00
IUUC-Psi-093451	Pelodiscus sinensis	26.69	5.00e-28	118.00
IUUC-Pno-094855	Phaeosphaeria nodorum	39.47	2.00e-08	52.40
IUUC-Ppa-096015	Physcomitrella patens	35.00	3.00e-47	182.00
IUUC-Pfo-096096	Poecilia formosa	25.84	1.00e-26	113.00
IUUC-Pab-098676	Pongo abelii	24.81	1.00e-26	113.00
IUUC-Pop-099432	Populus trichocarpa	61.94	6.00e-78	283.00
IUUC-Pca-100418	Procavia capensis	27.24	3.00e-12	65.50
IUUC-Ppe-101898	Prunus persica	55.59	2.00e-162	565.00
IUUC-Pva-103018	Pteropus vampyrus	27.00	3.00e-18	85.50
IUUC-Pgr-103423	Puccinia graminis	23.64	3.00e-09	57.00
IUUC-Ptt-103779	Puccinia triticina	22.88	1.00e-09	57.80
IUUC-Pte-104330	Pyrenophora teres	23.55	5.00e-11	62.00
IUUC-Pyt-104518	Pyrenophora triticirepentis	25.00	3.00e-12	66.20
IUUC-Rno-105708	Rattus norvegicus	25.81	1.00e-18	87.00
IUUC-Sha-106971	Sarcophilus harrisii	25.55	6.00e-28	117.00
IUUC-Smo-109086	Selaginella moellendorffii	37.76	2.00e-26	112.00
IUUC-Sit-110442	Setaria italica	41.62	5.00e-93	333.00
IUUC-Sly-110928	Solanum lycopersicum	49.55	6.00e-109	386.00
IUUC-Stu-112223	Solanum tuberosum	49.65	1.00e-104	372.00
IUUC-Sbi-114645	Sorghum bicolor	52.30	7.00e-42	163.00
IUUC-Ssc-116397	Sus scrofa	25.00	2.00e-28	119.00
IUUC-Tgu-117446	Taeniopygia guttata	27.50	3.00e-29	122.00
IUUC-Tru-118268	Takifugu rubripes	27.82	2.00e-28	119.00
IUUC-Tni-119735	Tetraodon nigroviridis	26.79	8.00e-22	97.40
IUUC-Tre-121937	Trichoderma reesei	23.27	6.00e-10	58.50
IUUC-Tvi-122428	Trichoderma virens	23.63	2.00e-11	63.50
IUUC-Tae-125203	Triticum aestivum	41.52	1.00e-95	343.00
IUUC-Tur-126458	Triticum urartu	49.39	7.00e-82	296.00
IUUC-Ttr-129273	Tursiops truncatus	25.33	1.00e-27	116.00
IUUC-Vda-129789	Verticillium dahliae	22.82	1.00e-09	57.80
IUUC-Vvi-131177	Vitis vinifera	59.07	3.00e-154	537.00
IUUC-Xtr-132374	Xenopus tropicalis	27.10	2.00e-32	133.00
IUUC-Xma-133267	Xiphophorus maculatus	26.55	2.00e-29	123.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence