iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007787

Ensembl Protein ID

AAS54257

UniProt Accession

Q751E0; Q751E0_ASHGO

Genbank Protein ID

AAS54257.1

Protein Name

AGL234Wp

Genbank Nucleotide ID

AE016820

Gene Name

AGOS_AGL234W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AGL234W	AAS54257	AAS54257

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.50e-49	159.3	392	428
UBD/Beta-Prp	2.80e-105	349.7	274	614

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH+ ++++l++ +  + lvsGs+D t+++WDlrtg +
   Q: 392  GHEQDIYSLDYfPAgDKLVSGSGDRTVRIWDLRTGQC 428
           8*********7755599******************98 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae...................................vtavkfspdgkilvtgseD 73
           +h+sv++cv fs+d+++latg+ ++t++v++v+tg ll++ls+++ +                                   +++v+fspdgk+l+tg+eD
   Q: 274  DHSSVVCCVRFSNDGEYLATGC-NKTTQVYKVSTGELLARLSDDSVAgvnneastgpanngtadnggensatiqpasssdlyIRSVCFSPDGKYLATGAED 373
           79********************.**********************999***************************************************** PP
   S: 74   rtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           ++i++wdl t k+++tl+ghe++++sl+++p gdklvsGs drt+r+wdl+tgqc+  tls++dgv++++v+++dg+++++GslDrtvr+Wd++tg+l+++
   Q: 374  KLIRIWDLTTKKILMTLQGHEQDIYSLDYFPAGDKLVSGSGDRTVRIWDLRTGQCSL-TLSIEDGVTTVAVSPGDGKYIAAGSLDRTVRVWDSETGFLVER 473
           *********************************************************.******************************************* PP
   S: 175  l.......tgghtdsvyslsfdsngkelvsgsldgtvklwdlq.......tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
           l       t gh+dsvys+ f+++g+ ++sgsld++vklwdl+       + +c +t++gh+d+v+sv+++++de+++sgs+D+ + +Wd+ sg++l +lq
   Q: 474  LdsenelsT-GHKDSVYSVVFTRDGQGVISGSLDRSVKLWDLRglngqksHATCEVTYTGHKDFVLSVATTQDDEYILSGSKDRGVLFWDTASGNPLLMLQ 573
           *******55.5****************************************************************************************** PP
   S: 262  lhnssvisvav.....lsfgdnvlvlgsedskvniwklkkn 297
           +h++svisvav     l+++  v+++gs+d+k++iwk++k+
   Q: 574  GHRNSVISVAVvngfpLGPDVGVFATGSGDCKARIWKYTKK 614
           **************999*********************986 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MSSSVSASQA KVNELLEAIR QEFQSVSQEA TSYRLQNQKD YDFKINQQLA EMQQIRNTVY 60
ELELTHRKMK DAYEEEIQRL KVELEQRDRQ LSQYAQGTAV PLAAPAASVV TASPAPAVGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAAGTT CGGTGAGCGC GTCGCAGGCG AAGGTTAACG AGTTGCTGGA GGCAATTCGG 60
CAGGAGTTCC AGAGCGTATC GCAGGAGGCG ACCAGCTACC GACTTCAGAA CCAGAAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR013890--Tscrpt_rep_Tup1_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08581--Tup_N
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0017053--C:transcriptional repressor complex
GO:0080025--F:phosphatidylinositol-3,5-bisphosphate binding
GO:0001191--F:transcriptional repressor activity, RNA polymerase II transcription factor binding
GO:0043486--P:histone exchange
GO:0035955--P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter
GO:0001198--P:negative regulation of mating-type specific transcription from RNA polymerase II promoter
GO:0000433--P:negative regulation of transcription from RNA polymerase II promoter by glucose
GO:0007070--P:negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle
GO:0016584--P:nucleosome positioning
GO:2000531--P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter
GO:2000217--P:regulation of invasive growth in response to glucose limitation
GO:2001020--P:regulation of response to DNA damage stimulus

KEGG

ago:AGOS_AGL234W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008112	Aspergillus clavatus	50.60	1.00e-102	364.00
IUUC-Afl-008410	Aspergillus flavus	50.00	8.00e-102	362.00
IUUC-Afu-008822	Aspergillus fumigatus	50.60	3.00e-101	360.00
IUUC-Ani-009447	Aspergillus nidulans	50.99	1.00e-103	368.00
IUUC-Ang-009633	Aspergillus niger	50.61	2.00e-102	363.00
IUUC-Aor-010122	Aspergillus oryzae	50.12	9.00e-102	362.00
IUUC-Ate-010265	Aspergillus terreus	50.24	4.00e-102	362.00
IUUC-Bgr-012206	Blumeria graminis	51.15	1.00e-108	385.00
IUUC-Bci-013662	Botrytis cinerea	53.79	8.00e-115	405.00
IUUC-Cre-022578	Chlamydomonas reinhardtii	32.85	3.00e-41	159.00
IUUC-Cgl-026593	Colletotrichum gloeosporioides	54.62	5.00e-116	408.00
IUUC-Cne-026944	Cryptococcus neoformans	48.29	2.00e-104	370.00
IUUC-Dse-031198	Dothistroma septosporum	50.39	8.00e-112	395.00
IUUC-Fox-037829	Fusarium oxysporum	52.56	3.00e-113	400.00
IUUC-Fso-038383	Fusarium solani	53.21	1.00e-115	408.00
IUUC-Ggr-039887	Gaeumannomyces graminis	54.69	2.00e-119	421.00
IUUC-Kpa-049111	Komagataella pastoris	66.58	1.00e-147	514.00
IUUC-Lma-053115	Leptosphaeria maculans	50.26	7.00e-105	372.00
IUUC-Mor-057042	Magnaporthe oryzae	52.99	4.00e-116	409.00
IUUC-Mpo-057414	Magnaporthe poae	54.69	1.00e-119	421.00
IUUC-Mla-058997	Melampsora laricipopulina	45.93	8.00e-95	339.00
IUUC-Mvi-060368	Microbotryum violaceum	36.25	3.00e-94	337.00
IUUC-Nfi-068326	Neosartorya fischeri	50.48	5.00e-103	366.00
IUUC-Ncr-068753	Neurospora crassa	54.01	1.00e-115	408.00
IUUC-Pno-095046	Phaeosphaeria nodorum	49.28	8.00e-92	328.00
IUUC-Pgr-103412	Puccinia graminis	44.03	8.00e-92	328.00
IUUC-Ptt-103788	Puccinia triticina	37.36	4.00e-69	253.00
IUUC-Pte-104272	Pyrenophora teres	51.55	7.00e-109	385.00
IUUC-Pyt-104514	Pyrenophora triticirepentis	51.55	7.00e-109	385.00
IUUC-Sce-106164	Saccharomyces cerevisiae	74.36	0.00e+00	652.00
IUUC-Sja-107987	Schizosaccharomyces japonicus	37.30	1.00e-107	381.00
IUUC-Spo-108357	Schizosaccharomyces pombe	49.32	4.00e-102	363.00
IUUC-Sre-115049	Sporisorium reilianum	46.87	1.00e-97	348.00
IUUC-Tre-121975	Trichoderma reesei	54.45	9.00e-116	408.00
IUUC-Tvi-122338	Trichoderma virens	53.75	5.00e-117	412.00
IUUC-Tme-127064	Tuber melanosporum	43.78	1.00e-131	461.00
IUUC-Uma-129593	Ustilago maydis	47.13	9.00e-99	352.00
IUUC-Vda-129718	Verticillium dahliae	54.45	1.00e-110	391.00
IUUC-Yli-134621	Yarrowia lipolytica	58.38	2.00e-127	447.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence