iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116186

Ensembl Protein ID

ENSSSCP00000025209.1

UniProt Accession

I3LM88; I3LM88_PIG

Genbank Protein ID

ENSSSCP00000025209

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU915669

Gene Name

HLTF

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000025293.1	ENSSSCT00000023239.1	ENSSSCP00000025209.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.50e-07	29.5	762	803

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiCl+++   p+++ C Hvf++ C+ q      ++++++++CPlCr
   Q: 762  CAICLDSLTV-PVITHCAHVFCKPCIcQV----IQNEQPHAKCPLCR 803
           ********88.999************444....599**********8 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSWMFKRDPV WKYLQTVQYG VHGNFPRLSY PTFFPRFEFQ DIIPPDDFLT SDEELDSVLF 60
GTLRGHVVGL RYYTGVVNNN EMVALQREPN NPYDKNAIKV NNVNGNQVGH LKKDLAAALA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGCCAGTC ACAAAGCGTC ACTTGTCTCT CAGATTGTTG CTGGAAGGGG TCGGCGTCGA 60
CGTCTGACTA GGCTCCCGGC GTCTCACCTT TCTGGAGTGC GCTCTTGCTC GCGGCTCTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR030065--HLTF
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN
SM00184--RING

Gene Ontology

GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003723--F:RNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006301--P:postreplication repair
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	38.63	2.00e-108	387.00
IUUC-Aml-001237	Ailuropoda melanoleuca	97.03	0.00e+00	1929.00
IUUC-Atr-003058	Amborella trichopoda	37.73	1.00e-105	377.00
IUUC-Apl-003679	Anas platyrhynchos	30.59	1.00e-35	145.00
IUUC-Aca-004994	Anolis carolinensis	66.63	0.00e+00	1232.00
IUUC-Aly-005898	Arabidopsis lyrata	42.41	2.00e-116	413.00
IUUC-Ath-007559	Arabidopsis thaliana	42.41	1.00e-117	417.00
IUUC-Ago-007997	Ashbya gossypii	34.30	7.00e-78	285.00
IUUC-Acl-008022	Aspergillus clavatus	30.03	7.00e-77	282.00
IUUC-Afl-008697	Aspergillus flavus	35.60	2.00e-84	306.00
IUUC-Afu-008767	Aspergillus fumigatus	34.17	1.00e-82	301.00
IUUC-Ani-009435	Aspergillus nidulans	34.37	8.00e-82	298.00
IUUC-Ang-009874	Aspergillus niger	33.68	7.00e-81	294.00
IUUC-Aor-010130	Aspergillus oryzae	36.66	8.00e-85	308.00
IUUC-Ate-010582	Aspergillus terreus	33.33	6.00e-77	282.00
IUUC-Ame-011743	Astyanax mexicanus	59.82	0.00e+00	640.00
IUUC-Bgr-012253	Blumeria graminis	32.33	9.00e-81	295.00
IUUC-Bta-013391	Bos taurus	94.76	0.00e+00	1915.00
IUUC-Bci-013741	Botrytis cinerea	38.93	5.00e-45	176.00
IUUC-Bdi-014267	Brachypodium distachyon	39.89	2.00e-114	406.00
IUUC-Bol-016075	Brassica oleracea	42.05	2.00e-119	423.00
IUUC-Bra-017057	Brassica rapa	42.49	5.00e-119	421.00
IUUC-Cja-019685	Callithrix jacchus	93.47	0.00e+00	1951.00
IUUC-Cfa-020485	Canis familiaris	95.55	0.00e+00	1896.00
IUUC-Cpo-021361	Cavia porcellus	88.28	0.00e+00	1053.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	29.40	4.00e-63	236.00
IUUC-Csa-023894	Chlorocebus sabaeus	93.97	0.00e+00	1902.00
IUUC-Cho-024891	Choloepus hoffmanni	79.65	0.00e+00	749.00
IUUC-Csv-026168	Ciona savignyi	29.90	7.00e-31	129.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	34.34	2.00e-87	317.00
IUUC-Cne-026829	Cryptococcus neoformans	36.41	5.00e-90	325.00
IUUC-Cme-027110	Cyanidioschyzon merolae	33.80	3.00e-89	323.00
IUUC-Dre-027867	Danio rerio	62.36	0.00e+00	701.00
IUUC-Dno-029517	Dasypus novemcinctus	93.67	0.00e+00	1841.00
IUUC-Dor-030590	Dipodomys ordii	86.17	0.00e+00	733.00
IUUC-Dse-031471	Dothistroma septosporum	30.39	4.00e-77	283.00
IUUC-Dme-031815	Drosophila melanogaster	30.74	9.00e-53	202.00
IUUC-Ete-032421	Echinops telfairi	75.88	0.00e+00	995.00
IUUC-Eca-034058	Equus caballus	94.85	0.00e+00	1866.00
IUUC-Eeu-034597	Erinaceus europaeus	77.45	0.00e+00	1447.00
IUUC-Fca-035390	Felis catus	96.14	0.00e+00	1885.00
IUUC-Fal-037486	Ficedula albicollis	32.01	9.00e-38	152.00
IUUC-Fox-038039	Fusarium oxysporum	33.83	5.00e-90	325.00
IUUC-Fso-038179	Fusarium solani	33.79	1.00e-87	318.00
IUUC-Gmo-038544	Gadus morhua	54.45	0.00e+00	652.00
IUUC-Ggr-039735	Gaeumannomyces graminis	31.67	5.00e-73	269.00
IUUC-Gga-040472	Gallus gallus	32.57	3.00e-38	154.00
IUUC-Gac-042401	Gasterosteus aculeatus	57.29	0.00e+00	679.00
IUUC-Gma-044315	Glycine max	37.73	1.00e-99	357.00
IUUC-Ggo-045628	Gorilla gorilla	93.29	0.00e+00	1879.00
IUUC-Hsa-045930	Homo sapiens	93.47	0.00e+00	1894.00
IUUC-Hvu-047747	Hordeum vulgare	38.26	1.00e-108	387.00
IUUC-Itr-048493	Ictidomys tridecemlineatus	93.30	0.00e+00	1889.00
IUUC-Kpa-049087	Komagataella pastoris	33.68	2.00e-82	300.00
IUUC-Lch-050617	Latimeria chalumnae	60.91	0.00e+00	1111.00
IUUC-Lpe-051724	Leersia perrieri	42.01	1.00e-118	420.00
IUUC-Loc-052785	Lepisosteus oculatus	64.77	0.00e+00	754.00
IUUC-Lma-052956	Leptosphaeria maculans	30.45	4.00e-77	283.00
IUUC-Laf-054309	Loxodonta africana	91.18	0.00e+00	1744.00
IUUC-Mcc-055493	Macaca mulatta	93.29	0.00e+00	1880.00
IUUC-Meu-056270	Macropus eugenii	77.97	0.00e+00	935.00
IUUC-Mor-056943	Magnaporthe oryzae	35.89	1.00e-89	324.00
IUUC-Mpo-057407	Magnaporthe poae	32.06	1.00e-78	288.00
IUUC-Mtr-058172	Medicago truncatula	41.63	1.00e-112	400.00
IUUC-Mla-059170	Melampsora laricipopulina	32.51	2.00e-74	273.00
IUUC-Mga-059553	Meleagris gallopavo	31.91	8.00e-38	152.00
IUUC-Mvi-060365	Microbotryum violaceum	33.39	7.00e-83	301.00
IUUC-Mmr-061043	Microcebus murinus	91.49	0.00e+00	1761.00
IUUC-Mdo-062919	Monodelphis domestica	81.29	0.00e+00	1514.00
IUUC-Mmu-064338	Mus musculus	83.58	0.00e+00	1675.00
IUUC-Mac-065666	Musa acuminata	35.30	9.00e-87	315.00
IUUC-Mpu-066781	Mustela putorius furo	95.94	0.00e+00	1903.00
IUUC-Mlu-068076	Myotis lucifugus	93.38	0.00e+00	1835.00
IUUC-Nfi-068386	Neosartorya fischeri	33.99	6.00e-81	295.00
IUUC-Ncr-068858	Neurospora crassa	36.67	2.00e-87	317.00
IUUC-Nle-069947	Nomascus leucogenys	93.77	0.00e+00	1901.00
IUUC-Opr-070388	Ochotona princeps	87.16	0.00e+00	1178.00
IUUC-Ont-071782	Oreochromis niloticus	60.89	0.00e+00	669.00
IUUC-Oan-073331	Ornithorhynchus anatinus	80.90	0.00e+00	1366.00
IUUC-Ocu-074705	Oryctolagus cuniculus	93.08	0.00e+00	1805.00
IUUC-Oba-075881	Oryza barthii	41.71	7.00e-116	411.00
IUUC-Obr-076344	Oryza brachyantha	41.11	1.00e-111	396.00
IUUC-Ogl-076957	Oryza glaberrima	41.71	7.00e-116	411.00
IUUC-Ogu-078648	Oryza glumaepatula	41.04	1.00e-110	394.00
IUUC-Oin-079449	Oryza indica	41.15	3.00e-111	395.00
IUUC-Olo-080721	Oryza longistaminata	40.97	2.00e-111	395.00
IUUC-Ome-081579	Oryza meridionalis	40.77	1.00e-111	397.00
IUUC-Oni-083054	Oryza nivara	41.15	3.00e-111	395.00
IUUC-Opu-083706	Oryza punctata	41.25	6.00e-112	398.00
IUUC-Oru-085259	Oryza rufipogon	41.15	3.00e-111	395.00
IUUC-Osa-085568	Oryza sativa	41.41	3.00e-98	352.00
IUUC-Ola-086830	Oryzias latipes	54.86	5.00e-179	621.00
IUUC-Olu-087669	Ostreococcus lucimarinus	28.57	5.00e-57	216.00
IUUC-Oga-088120	Otolemur garnettii	86.61	0.00e+00	1642.00
IUUC-Oar-089293	Ovis aries	94.96	0.00e+00	1934.00
IUUC-Ptr-091418	Pan troglodytes	93.47	0.00e+00	1897.00
IUUC-Pan-092579	Papio anubis	93.59	0.00e+00	1445.00
IUUC-Psi-093626	Pelodiscus sinensis	71.32	0.00e+00	1211.00
IUUC-Pno-094841	Phaeosphaeria nodorum	38.46	9.00e-86	311.00
IUUC-Ppa-095291	Physcomitrella patens	46.52	8.00e-141	494.00
IUUC-Pfo-096540	Poecilia formosa	56.48	0.00e+00	659.00
IUUC-Pab-098010	Pongo abelii	93.67	0.00e+00	1897.00
IUUC-Pop-099320	Populus trichocarpa	36.55	6.00e-106	378.00
IUUC-Pca-100648	Procavia capensis	78.83	0.00e+00	1501.00
IUUC-Ppe-102077	Prunus persica	42.28	2.00e-98	353.00
IUUC-Pva-102896	Pteropus vampyrus	91.42	0.00e+00	907.00
IUUC-Pgr-103403	Puccinia graminis	31.52	1.00e-73	271.00
IUUC-Ptt-103966	Puccinia triticina	32.11	8.00e-73	268.00
IUUC-Pte-104242	Pyrenophora teres	31.84	2.00e-79	290.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	31.34	2.00e-78	287.00
IUUC-Rno-106130	Rattus norvegicus	83.88	0.00e+00	1673.00
IUUC-Sce-106159	Saccharomyces cerevisiae	31.79	1.00e-78	287.00
IUUC-Sha-107221	Sarcophilus harrisii	82.28	0.00e+00	1541.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	35.15	3.00e-88	320.00
IUUC-Spo-108305	Schizosaccharomyces pombe	30.64	4.00e-80	292.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	34.35	2.00e-85	310.00
IUUC-Smo-109629	Selaginella moellendorffii	43.72	2.00e-128	452.00
IUUC-Sit-109770	Setaria italica	41.77	8.00e-115	407.00
IUUC-Sly-111908	Solanum lycopersicum	37.86	2.00e-106	380.00
IUUC-Stu-112600	Solanum tuberosum	37.84	2.00e-106	380.00
IUUC-Sar-113719	Sorex araneus	93.16	0.00e+00	1723.00
IUUC-Sbi-114616	Sorghum bicolor	36.48	2.00e-103	370.00
IUUC-Sre-114938	Sporisorium reilianum	28.83	7.00e-74	272.00
IUUC-Tru-117768	Takifugu rubripes	51.97	0.00e+00	919.00
IUUC-Tsy-118957	Tarsius syrichta	85.87	0.00e+00	1675.00
IUUC-Tni-120618	Tetraodon nigroviridis	52.67	0.00e+00	963.00
IUUC-Tca-121146	Theobroma cacao	37.63	4.00e-108	385.00
IUUC-Tre-121896	Trichoderma reesei	34.62	7.00e-95	342.00
IUUC-Tvi-122597	Trichoderma virens	33.89	3.00e-90	326.00
IUUC-Tae-123773	Triticum aestivum	41.54	7.00e-106	378.00
IUUC-Tur-125999	Triticum urartu	38.63	3.00e-108	386.00
IUUC-Tme-126953	Tuber melanosporum	33.75	3.00e-87	316.00
IUUC-Tbe-127612	Tupaia belangeri	84.93	0.00e+00	835.00
IUUC-Ttr-128243	Tursiops truncatus	91.69	0.00e+00	1421.00
IUUC-Uma-129441	Ustilago maydis	29.00	2.00e-74	274.00
IUUC-Vda-129933	Verticillium dahliae	36.82	9.00e-81	295.00
IUUC-Vpa-130672	Vicugna pacos	96.18	0.00e+00	1774.00
IUUC-Vvi-131204	Vitis vinifera	42.65	1.00e-120	427.00
IUUC-Xtr-132730	Xenopus tropicalis	61.68	0.00e+00	1229.00
IUUC-Xma-133384	Xiphophorus maculatus	52.33	0.00e+00	951.00
IUUC-Yli-134350	Yarrowia lipolytica	32.11	8.00e-75	275.00
IUUC-Zma-134966	Zea mays	42.99	2.00e-122	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence