iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074539

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02034345

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010937.3	ENSOCUT00000010933.3	ENSOCUP00000009408.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	5.80e-16	58.1	153	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ ++LqhLCRlaI++c+g+     i++LPLP +LkdYL+++++q
   Q: 153  TKPLYTSAPPLQHLCRLAINKCTGT-----IWGLPLPTRLKDYLEEYKFQ 197
           678999*******************.....8***************9886 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MTLRCLEPSG NGAEGTRSQW GTTGPPEEPS PEAARLAKAL RELSQTGWYW GSMTVNEAKE 60
KLKEAPERTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCTCTCTG GCTGAGCGCG TCTGTGGGCG ACTGTGGCAT CTGTCCGCTG GAACCTGGCG 60
ACACGGAACC AGCAGTGCGC CACCCCCTCC TCTTTTGTCA CCGCTTCGGA CCCGCAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	95.94	5.00e-105	372.00
IUUC-Apl-003484	Anas platyrhynchos	78.29	3.00e-70	256.00
IUUC-Aca-004253	Anolis carolinensis	69.94	3.00e-69	254.00
IUUC-Aly-006377	Arabidopsis lyrata	31.82	4.70e-01	29.30
IUUC-Ath-007106	Arabidopsis thaliana	33.90	2.70e-01	29.60
IUUC-Ame-011267	Astyanax mexicanus	61.18	8.00e-58	216.00
IUUC-Bta-013183	Bos taurus	94.42	1.00e-98	351.00
IUUC-Bra-017915	Brassica rapa	32.20	5.20e-01	28.50
IUUC-Cja-018862	Callithrix jacchus	94.92	3.00e-99	353.00
IUUC-Cfa-020226	Canis familiaris	94.97	9.00e-98	348.00
IUUC-Cpo-022414	Cavia porcellus	94.42	1.00e-101	361.00
IUUC-Csa-023758	Chlorocebus sabaeus	94.42	4.00e-102	363.00
IUUC-Cho-024471	Choloepus hoffmanni	83.87	4.00e-70	256.00
IUUC-Dre-028288	Danio rerio	56.54	8.00e-62	229.00
IUUC-Dno-029036	Dasypus novemcinctus	94.42	5.00e-104	369.00
IUUC-Dor-030447	Dipodomys ordii	97.33	2.00e-85	306.00
IUUC-Ete-033023	Echinops telfairi	92.89	6.00e-108	382.00
IUUC-Fca-036469	Felis catus	95.94	7.00e-100	355.00
IUUC-Fal-036642	Ficedula albicollis	73.29	2.00e-69	254.00
IUUC-Gmo-039331	Gadus morhua	52.38	2.00e-34	137.00
IUUC-Gga-040809	Gallus gallus	75.32	2.00e-70	257.00
IUUC-Gac-041398	Gasterosteus aculeatus	59.88	2.00e-58	218.00
IUUC-Ggo-045341	Gorilla gorilla	95.43	2.00e-99	353.00
IUUC-Hsa-046557	Homo sapiens	94.92	1.00e-110	391.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	79.71	6.00e-90	323.00
IUUC-Lch-050160	Latimeria chalumnae	61.74	3.00e-49	187.00
IUUC-Loc-051825	Lepisosteus oculatus	61.90	4.00e-59	220.00
IUUC-Laf-053560	Loxodonta africana	94.42	8.00e-98	348.00
IUUC-Mcc-055890	Macaca mulatta	94.42	3.00e-98	350.00
IUUC-Meu-056218	Macropus eugenii	79.70	7.00e-94	335.00
IUUC-Mga-059755	Meleagris gallopavo	77.48	8.00e-69	252.00
IUUC-Mmr-061387	Microcebus murinus	95.94	2.00e-103	367.00
IUUC-Mdo-062383	Monodelphis domestica	82.23	3.00e-95	340.00
IUUC-Mmu-063443	Mus musculus	95.43	2.00e-102	364.00
IUUC-Mpu-066459	Mustela putorius furo	95.43	2.00e-99	354.00
IUUC-Mlu-068040	Myotis lucifugus	95.94	5.00e-106	376.00
IUUC-Nle-069016	Nomascus leucogenys	90.36	2.00e-96	344.00
IUUC-Opr-071087	Ochotona princeps	89.85	3.00e-103	367.00
IUUC-Ont-072340	Oreochromis niloticus	57.37	8.00e-59	219.00
IUUC-Oan-073443	Ornithorhynchus anatinus	77.16	7.00e-87	312.00
IUUC-Ogu-078951	Oryza glumaepatula	27.03	3.60e-02	32.70
IUUC-Oin-079476	Oryza indica	27.03	3.00e-02	33.10
IUUC-Oni-082613	Oryza nivara	27.03	3.00e-02	33.10
IUUC-Oru-085265	Oryza rufipogon	27.03	3.10e-02	33.10
IUUC-Ola-087004	Oryzias latipes	59.62	2.00e-53	201.00
IUUC-Oga-088438	Otolemur garnettii	94.92	1.00e-102	364.00
IUUC-Oar-089932	Ovis aries	94.42	3.00e-98	350.00
IUUC-Ptr-091037	Pan troglodytes	95.43	2.00e-99	353.00
IUUC-Pan-092767	Papio anubis	94.42	2.00e-98	350.00
IUUC-Psi-093099	Pelodiscus sinensis	75.32	2.00e-71	260.00
IUUC-Pma-094671	Petromyzon marinus	45.40	2.00e-35	142.00
IUUC-Pfo-097073	Poecilia formosa	48.95	7.00e-53	199.00
IUUC-Pab-098319	Pongo abelii	94.92	1.00e-104	371.00
IUUC-Pca-101117	Procavia capensis	93.40	1.00e-98	351.00
IUUC-Pva-102117	Pteropus vampyrus	94.42	6.00e-97	346.00
IUUC-Rno-105913	Rattus norvegicus	93.94	3.00e-101	360.00
IUUC-Sha-106500	Sarcophilus harrisii	81.73	6.00e-94	336.00
IUUC-Ssc-115252	Sus scrofa	96.45	2.00e-104	370.00
IUUC-Tgu-117524	Taeniopygia guttata	75.32	9.00e-69	251.00
IUUC-Tsy-119335	Tarsius syrichta	92.67	2.00e-82	296.00
IUUC-Tni-120263	Tetraodon nigroviridis	52.94	5.00e-54	203.00
IUUC-Tca-121866	Theobroma cacao	38.10	1.40e-01	30.40
IUUC-Tbe-127915	Tupaia belangeri	94.42	5.00e-96	343.00
IUUC-Ttr-128372	Tursiops truncatus	95.94	7.00e-104	369.00
IUUC-Vpa-130422	Vicugna pacos	98.67	1.00e-86	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence