iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003404

Ensembl Protein ID

ENSAPLP00000011188.1

UniProt Accession

U3IVB5; U3IVB5_ANAPL

Genbank Protein ID

ENSAPLP00000011188

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01001157

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011375.1	ENSAPLT00000011911.1	ENSAPLP00000011188.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.60e-09	35.9	260	298
UBD/Alpha-Helix/CUE	1.30e-11	43.9	375	416

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 260  CAICWDSMQS-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 298
           ********99.9*****************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 375  QLNAMAHQIQEMFPQVPYHLVLQDL-QLTRSVEITTDNILEGR 416
           5889*********************.***************95 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LVLWVLVNTA CCFLMLVAKL IQYVVFGPLR VSERQHLKDK FWNFIFYKFI FIFGVLNVQT 60
VEEVVMWCLW FSGLVFLHLM VQLCKDRFEY LSFSPTTPMS SHIRVLTLLI AMLMSCCGLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGTGCTTT GGGTAGGTCG ACAGTTAATT GCAAATTTCT TCGTCACATC TGACAAGCAG 60
TTTTCCAGGC CCGCATGTTC GGCTCCTTAC TGCTTTGCTT TAAAGCAGGC TCCCAGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	26.52	8.00e-24	104.00
IUUC-Aml-001300	Ailuropoda melanoleuca	86.93	0.00e+00	951.00
IUUC-Atr-002892	Amborella trichopoda	29.36	4.00e-33	135.00
IUUC-Aca-004559	Anolis carolinensis	88.49	0.00e+00	909.00
IUUC-Aly-005440	Arabidopsis lyrata	29.13	7.00e-32	131.00
IUUC-Ath-006702	Arabidopsis thaliana	31.80	8.00e-36	144.00
IUUC-Ago-007894	Ashbya gossypii	26.63	3.00e-12	66.60
IUUC-Ani-009133	Aspergillus nidulans	21.92	5.00e-15	75.90
IUUC-Ang-009612	Aspergillus niger	24.15	3.00e-16	80.10
IUUC-Ame-011640	Astyanax mexicanus	76.28	0.00e+00	775.00
IUUC-Bta-012980	Bos taurus	87.99	0.00e+00	978.00
IUUC-Bci-013675	Botrytis cinerea	29.94	2.00e-11	63.90
IUUC-Bdi-015070	Brachypodium distachyon	34.38	7.00e-35	141.00
IUUC-Bol-015593	Brassica oleracea	31.23	1.00e-35	144.00
IUUC-Bra-017516	Brassica rapa	31.93	4.00e-36	145.00
IUUC-Cel-018598	Caenorhabditis elegans	24.11	2.00e-30	126.00
IUUC-Cja-019577	Callithrix jacchus	88.08	0.00e+00	991.00
IUUC-Cfa-020793	Canis familiaris	87.50	0.00e+00	962.00
IUUC-Cpo-022387	Cavia porcellus	88.43	0.00e+00	955.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	26.20	8.00e-25	107.00
IUUC-Csa-023168	Chlorocebus sabaeus	88.08	0.00e+00	991.00
IUUC-Cho-024433	Choloepus hoffmanni	90.31	0.00e+00	808.00
IUUC-Cin-025215	Ciona intestinalis	49.62	3.00e-141	494.00
IUUC-Csv-026133	Ciona savignyi	48.95	6.00e-131	460.00
IUUC-Cne-027002	Cryptococcus neoformans	27.52	1.00e-25	110.00
IUUC-Cme-027285	Cyanidioschyzon merolae	29.66	1.00e-22	101.00
IUUC-Dre-027594	Danio rerio	75.39	0.00e+00	732.00
IUUC-Dno-029407	Dasypus novemcinctus	89.07	0.00e+00	957.00
IUUC-Dor-030961	Dipodomys ordii	88.35	0.00e+00	970.00
IUUC-Ete-032962	Echinops telfairi	80.82	0.00e+00	809.00
IUUC-Eca-033683	Equus caballus	85.97	0.00e+00	939.00
IUUC-Eeu-034515	Erinaceus europaeus	92.59	1.00e-74	273.00
IUUC-Fca-035398	Felis catus	90.39	0.00e+00	940.00
IUUC-Fal-036758	Ficedula albicollis	86.52	0.00e+00	937.00
IUUC-Fox-037902	Fusarium oxysporum	29.24	2.00e-15	77.40
IUUC-Fso-038418	Fusarium solani	29.80	4.00e-14	73.20
IUUC-Gmo-039014	Gadus morhua	73.45	0.00e+00	726.00
IUUC-Ggr-040076	Gaeumannomyces graminis	30.41	1.00e-13	71.60
IUUC-Gga-040575	Gallus gallus	95.55	0.00e+00	1064.00
IUUC-Gac-041414	Gasterosteus aculeatus	72.90	0.00e+00	712.00
IUUC-Gma-044123	Glycine max	27.63	2.00e-32	133.00
IUUC-Hsa-046272	Homo sapiens	88.08	0.00e+00	992.00
IUUC-Hvu-047279	Hordeum vulgare	30.74	1.00e-35	143.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	88.08	0.00e+00	952.00
IUUC-Lch-050491	Latimeria chalumnae	81.71	0.00e+00	835.00
IUUC-Loc-052758	Lepisosteus oculatus	80.27	0.00e+00	802.00
IUUC-Lma-052997	Leptosphaeria maculans	24.73	2.00e-15	77.40
IUUC-Laf-053452	Loxodonta africana	88.71	0.00e+00	966.00
IUUC-Mcc-055820	Macaca mulatta	88.32	0.00e+00	966.00
IUUC-Meu-056726	Macropus eugenii	84.96	0.00e+00	749.00
IUUC-Mor-057082	Magnaporthe oryzae	30.19	1.00e-13	71.20
IUUC-Mpo-057573	Magnaporthe poae	31.45	1.00e-14	74.30
IUUC-Mtr-058601	Medicago truncatula	27.96	1.00e-32	134.00
IUUC-Mla-059168	Melampsora laricipopulina	25.85	3.00e-25	110.00
IUUC-Mga-059937	Meleagris gallopavo	95.16	0.00e+00	1015.00
IUUC-Mmr-060730	Microcebus murinus	89.15	0.00e+00	962.00
IUUC-Mdo-062771	Monodelphis domestica	89.30	0.00e+00	981.00
IUUC-Mmu-064219	Mus musculus	88.01	0.00e+00	980.00
IUUC-Mac-064789	Musa acuminata	27.63	2.00e-33	136.00
IUUC-Mpu-066796	Mustela putorius furo	87.96	0.00e+00	957.00
IUUC-Mlu-068189	Myotis lucifugus	85.77	0.00e+00	927.00
IUUC-Ncr-068742	Neurospora crassa	29.88	4.00e-14	73.20
IUUC-Nle-069239	Nomascus leucogenys	88.08	0.00e+00	991.00
IUUC-Opr-070702	Ochotona princeps	80.07	3.00e-129	455.00
IUUC-Ont-072033	Oreochromis niloticus	74.40	0.00e+00	773.00
IUUC-Oan-073717	Ornithorhynchus anatinus	83.53	0.00e+00	858.00
IUUC-Ocu-074145	Oryctolagus cuniculus	88.61	0.00e+00	991.00
IUUC-Oba-075221	Oryza barthii	28.52	2.00e-33	136.00
IUUC-Obr-076914	Oryza brachyantha	29.43	6.00e-35	141.00
IUUC-Ogl-077929	Oryza glaberrima	51.16	1.00e-11	62.40
IUUC-Ogu-078124	Oryza glumaepatula	28.52	2.00e-33	136.00
IUUC-Oin-080013	Oryza indica	28.86	4.00e-32	132.00
IUUC-Olo-080247	Oryza longistaminata	28.71	1.00e-29	123.00
IUUC-Ome-081769	Oryza meridionalis	29.05	1.00e-34	140.00
IUUC-Oni-082946	Oryza nivara	28.52	2.00e-33	136.00
IUUC-Opu-083268	Oryza punctata	27.24	4.00e-22	99.40
IUUC-Oru-085114	Oryza rufipogon	28.52	2.00e-33	136.00
IUUC-Osa-085829	Oryza sativa	29.05	3.00e-34	139.00
IUUC-Ola-087152	Oryzias latipes	73.06	0.00e+00	751.00
IUUC-Olu-087894	Ostreococcus lucimarinus	29.17	1.00e-26	113.00
IUUC-Oga-088486	Otolemur garnettii	88.63	0.00e+00	959.00
IUUC-Oar-089310	Ovis aries	87.99	0.00e+00	978.00
IUUC-Ptr-090649	Pan troglodytes	88.35	0.00e+00	986.00
IUUC-Pan-091692	Papio anubis	83.63	0.00e+00	927.00
IUUC-Psi-093064	Pelodiscus sinensis	95.73	0.00e+00	785.00
IUUC-Pma-094763	Petromyzon marinus	78.28	9.00e-99	352.00
IUUC-Ppa-095969	Physcomitrella patens	29.31	7.00e-40	158.00
IUUC-Pfo-096810	Poecilia formosa	73.43	0.00e+00	756.00
IUUC-Pab-097859	Pongo abelii	88.50	0.00e+00	969.00
IUUC-Pop-099576	Populus trichocarpa	27.06	3.00e-28	119.00
IUUC-Pca-100344	Procavia capensis	87.77	0.00e+00	934.00
IUUC-Ppe-101829	Prunus persica	28.19	9.00e-35	140.00
IUUC-Pva-103114	Pteropus vampyrus	60.32	1.00e-166	579.00
IUUC-Pgr-103286	Puccinia graminis	24.24	2.00e-21	97.80
IUUC-Ptt-103919	Puccinia triticina	24.01	9.00e-20	91.30
IUUC-Pte-104372	Pyrenophora teres	24.87	1.00e-17	84.70
IUUC-Pyt-104456	Pyrenophora triticirepentis	24.06	2.00e-15	77.80
IUUC-Rno-105880	Rattus norvegicus	86.14	0.00e+00	953.00
IUUC-Sce-106348	Saccharomyces cerevisiae	32.00	7.00e-09	55.10
IUUC-Sha-107015	Sarcophilus harrisii	91.05	0.00e+00	956.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	22.53	4.00e-18	85.90
IUUC-Spo-108308	Schizosaccharomyces pombe	22.77	1.00e-19	90.90
IUUC-Ssl-108558	Sclerotinia sclerotiorum	30.57	2.00e-11	64.30
IUUC-Smo-109664	Selaginella moellendorffii	30.09	6.00e-33	135.00
IUUC-Sit-110091	Setaria italica	32.90	3.00e-34	139.00
IUUC-Sly-111819	Solanum lycopersicum	30.25	2.00e-34	139.00
IUUC-Stu-112048	Solanum tuberosum	26.95	2.00e-29	123.00
IUUC-Sar-113397	Sorex araneus	94.07	0.00e+00	736.00
IUUC-Sbi-114192	Sorghum bicolor	28.11	2.00e-35	142.00
IUUC-Sre-115212	Sporisorium reilianum	25.65	9.00e-21	95.10
IUUC-Ssc-115988	Sus scrofa	80.90	1.00e-130	458.00
IUUC-Tgu-116717	Taeniopygia guttata	95.02	0.00e+00	991.00
IUUC-Tru-117805	Takifugu rubripes	72.16	0.00e+00	781.00
IUUC-Tsy-119442	Tarsius syrichta	82.26	0.00e+00	878.00
IUUC-Tni-119777	Tetraodon nigroviridis	70.76	2.00e-177	615.00
IUUC-Tca-121462	Theobroma cacao	28.52	1.00e-32	134.00
IUUC-Tre-122204	Trichoderma reesei	31.25	2.00e-13	70.90
IUUC-Tvi-122550	Trichoderma virens	30.56	2.00e-13	71.20
IUUC-Tae-125239	Triticum aestivum	29.81	1.00e-36	147.00
IUUC-Tur-126538	Triticum urartu	26.89	1.00e-23	104.00
IUUC-Tme-127197	Tuber melanosporum	28.52	5.00e-21	96.30
IUUC-Tbe-127322	Tupaia belangeri	64.16	7.00e-106	377.00
IUUC-Ttr-128181	Tursiops truncatus	87.81	0.00e+00	979.00
IUUC-Vda-129968	Verticillium dahliae	33.11	3.00e-14	73.60
IUUC-Vpa-130483	Vicugna pacos	82.38	0.00e+00	636.00
IUUC-Vvi-130944	Vitis vinifera	28.96	8.00e-32	131.00
IUUC-Xtr-132614	Xenopus tropicalis	80.53	0.00e+00	779.00
IUUC-Xma-133943	Xiphophorus maculatus	73.47	0.00e+00	754.00
IUUC-Yli-134552	Yarrowia lipolytica	36.25	7.00e-11	61.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence