iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015941

Ensembl Protein ID

Bo4g045520.1

UniProt Accession

A0A0D3BSN6; A0A0D3BSN6_BRAOL

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo4g045520	Bo4g045520.1	Bo4g045520.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.60e-77	261.3	200	994

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgyeqqDaqEf 95
           Gl NlgNtC++NSvLQ L+++  lr+ l++ + +++         g+l++sl+klf+e        +++++p +++ +l+++a++f+gy+q+D++E+
   Q: 200  GLVNLGNTCFFNSVLQNLLSLDRLRDRLFK-EDQSCG--------GPLVSSLKKLFTEAAseaGFFNSVINPWDFFGTLCSKAPQFRGYQQHDSHEL 287
           9*****************************.666665........69************866566678***************************** PP
   S: 96   laflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke....... 185
           l++lld+l+ e         ++++         ++ + +++++++l++ +F+g+++s+i clec+++s+ +epfldlslpvp+k++t  +       
   Q: 288  LRCLLDGLSIEE--------MSLR---------KKHDGDESEKPTLVDSVFGGEVSSTISCLECGHSSKVYEPFLDLSLPVPSKKQTLSQeersklt 367
           *********988........2232.........2447789999***************************************9998876699***** PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 368  pptkvfknvedskdssepvstmtfdnnqvpeiivtqkemeevgsfwcesfgievshnetdlvsqggvsdnddgsakqkdkeaitqcskdtassgide 464
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 465  aqvwgyplaneelpllvvdsqvmnmpykgdiyyddktvaegkgekqacpivrqtfesstetlmpdndgsakpdkeamqcsketasseideaqvwgyp 561
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 562  dighsfssakpcadeevpllvadsqvlcmpykddktvaedkgetsssyvsghhdqqtvdyvdfswffeepdvafddktvrecedevssslmsshhgk 658
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 659  tvdyvdlnepgvscnaktikeregevssslasshhgqtvdyvdssgcfdkadvscndktvrkcegeapssfvsshhgkkienadyywfsvepeiskg 755
           ************************************************************************************************* PP
   S: 186  ....................................slqdcLesftkeeelegenkyycekck.................................. 212
                                               s+++cL++ftk+e l ++n+++ce+c                                   
   Q: 756  pvfgpptiaevceagfmgvssnsdaevvlddldspvSVESCLAMFTKPEILSEDNAWHCENCStnklqrlrekrelvgsgwvydtifnqsftdfknw 852
           **************************************************************97766666666666666666666666666666666 PP
   S: 213  ...............kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke.kkkYeLiavvvHsGslssG 293
                           ++ a k++ ++k P+vL++hLkRfs  +++++ +k+  +v f++ +dl  ++  ++++++e +  Y L + v HsG+++ G
   Q: 853  dtiyddeavdseevvVRSAAIKRVLVNKAPPVLTIHLKRFSQ-NARGRLSKLRGHVAFNEFIDLGLYMDMESRQDEEdQPVYMLAGLVEHSGTMGRG 948
           6555555555554444444*********************65.5669999*********99****9888766665554889**************** PP
   S: 294  HYvayvknekgk......WllfdDskVtevkeeevleetgstaYvlfYk 336
           HYvay++ ++++      W++ +D  V++v+ eevl+   s+aY+lfY+
   Q: 949  HYVAYIRGDDKErrdssvWYRASDYFVRQVSFEEVLR---SEAYILFYQ 994
           *******97777788999*******************...********8 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MGKQLKKGRA PPGGNQFSKK VAKQSAETVM EQRSCVHFDK CVDLNKLLKK MKACERIKCR 60
DCKEGVDMKR RSEGEVSSFS CDAAKRAVWL CLECGRYCCG GVGLPTEPQS HVMRHIKMTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAGC AGTTAAAGAA AGGTCGAGCT CCTCCAGGTG GGAATCAGTT CTCCAAGAAG 60
GTAGCTAAGC AAAGCGCGGA GACAGTGATG GAACAAAGAT CTTGTGTGCA TTTTGATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001931	Ailuropoda melanoleuca	29.12	9.00e-35	141.00
IUUC-Apl-004145	Anas platyrhynchos	30.36	1.00e-37	151.00
IUUC-Ath-006732	Arabidopsis thaliana	46.06	1.00e-157	550.00
IUUC-Bta-013362	Bos taurus	29.69	2.00e-35	144.00
IUUC-Bra-016751	Brassica rapa	73.58	0.00e+00	1044.00
IUUC-Cja-019177	Callithrix jacchus	29.45	9.00e-35	142.00
IUUC-Cfa-020051	Canis familiaris	30.02	6.00e-35	142.00
IUUC-Cpo-021886	Cavia porcellus	30.38	2.00e-37	150.00
IUUC-Csa-024103	Chlorocebus sabaeus	29.69	8.00e-36	145.00
IUUC-Cho-024315	Choloepus hoffmanni	42.34	3.00e-17	83.60
IUUC-Dre-028106	Danio rerio	28.86	6.00e-32	132.00
IUUC-Dno-029409	Dasypus novemcinctus	29.95	9.00e-36	145.00
IUUC-Dor-030438	Dipodomys ordii	34.58	1.00e-21	98.60
IUUC-Eca-033479	Equus caballus	29.95	1.00e-35	144.00
IUUC-Fca-036320	Felis catus	29.29	6.00e-35	142.00
IUUC-Fal-037029	Ficedula albicollis	30.42	8.00e-36	145.00
IUUC-Gmo-039228	Gadus morhua	30.89	1.00e-31	131.00
IUUC-Gga-040527	Gallus gallus	30.12	2.00e-36	147.00
IUUC-Gac-042406	Gasterosteus aculeatus	32.49	7.00e-30	125.00
IUUC-Ggo-045598	Gorilla gorilla	29.22	3.00e-34	140.00
IUUC-Hsa-046598	Homo sapiens	29.45	8.00e-35	142.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	29.52	6.00e-38	152.00
IUUC-Lpe-050703	Leersia perrieri	42.21	2.00e-50	194.00
IUUC-Loc-051814	Lepisosteus oculatus	30.61	2.00e-31	131.00
IUUC-Laf-053732	Loxodonta africana	29.74	3.00e-35	143.00
IUUC-Mcc-054661	Macaca mulatta	29.45	2.00e-35	144.00
IUUC-Meu-055967	Macropus eugenii	28.22	5.00e-26	112.00
IUUC-Mga-059551	Meleagris gallopavo	30.00	2.00e-37	150.00
IUUC-Mmr-061747	Microcebus murinus	30.23	4.00e-34	139.00
IUUC-Mdo-062220	Monodelphis domestica	28.92	8.00e-36	145.00
IUUC-Mmu-063582	Mus musculus	31.12	1.00e-38	154.00
IUUC-Mpu-066339	Mustela putorius furo	28.88	6.00e-35	142.00
IUUC-Mlu-067511	Myotis lucifugus	29.95	1.00e-34	141.00
IUUC-Nle-069252	Nomascus leucogenys	29.69	2.00e-35	144.00
IUUC-Opr-070969	Ochotona princeps	29.97	4.00e-34	139.00
IUUC-Ont-071786	Oreochromis niloticus	28.81	4.00e-33	136.00
IUUC-Ocu-074704	Oryctolagus cuniculus	30.23	8.00e-35	142.00
IUUC-Oba-075094	Oryza barthii	42.86	9.00e-52	198.00
IUUC-Ogl-077739	Oryza glaberrima	42.86	5.00e-52	199.00
IUUC-Ogu-078851	Oryza glumaepatula	42.86	8.00e-52	199.00
IUUC-Oin-079402	Oryza indica	42.86	8.00e-52	199.00
IUUC-Olo-080431	Oryza longistaminata	42.86	6.00e-52	199.00
IUUC-Ome-081580	Oryza meridionalis	42.48	4.00e-52	199.00
IUUC-Oni-082644	Oryza nivara	42.86	8.00e-52	199.00
IUUC-Opu-083452	Oryza punctata	41.83	8.00e-52	199.00
IUUC-Osa-085858	Oryza sativa	42.86	8.00e-52	199.00
IUUC-Ola-087238	Oryzias latipes	30.95	9.00e-34	138.00
IUUC-Oga-088713	Otolemur garnettii	29.45	1.00e-34	141.00
IUUC-Oar-089887	Ovis aries	29.45	3.00e-35	143.00
IUUC-Ptr-091670	Pan troglodytes	29.22	3.00e-34	140.00
IUUC-Pan-092293	Papio anubis	29.45	2.00e-35	144.00
IUUC-Psi-093101	Pelodiscus sinensis	28.54	1.00e-33	138.00
IUUC-Pab-098539	Pongo abelii	31.63	3.00e-31	130.00
IUUC-Pca-100610	Procavia capensis	30.87	7.00e-24	105.00
IUUC-Rno-105237	Rattus norvegicus	30.00	6.00e-37	149.00
IUUC-Sha-106889	Sarcophilus harrisii	30.79	1.00e-33	137.00
IUUC-Sar-113530	Sorex araneus	29.45	2.00e-34	140.00
IUUC-Ssc-116091	Sus scrofa	29.72	7.00e-35	142.00
IUUC-Tgu-117478	Taeniopygia guttata	30.26	3.00e-35	143.00
IUUC-Tru-118640	Takifugu rubripes	32.06	4.00e-35	143.00
IUUC-Tsy-118869	Tarsius syrichta	30.69	5.00e-27	116.00
IUUC-Tur-126788	Triticum urartu	39.47	6.00e-46	179.00
IUUC-Tbe-128041	Tupaia belangeri	36.15	1.00e-24	108.00
IUUC-Ttr-128271	Tursiops truncatus	30.36	5.00e-36	145.00
IUUC-Vpa-130674	Vicugna pacos	29.45	1.00e-34	141.00
IUUC-Xtr-131869	Xenopus tropicalis	30.55	1.00e-35	144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence