iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129748

Ensembl Protein ID

EGY17948

UniProt Accession

G2WSN4; G2WSN4_VERDV

Genbank Protein ID

EGY17948.1

Protein Name

Ubiquitin-protein ligase E3C

Genbank Nucleotide ID

DS572696

Gene Name

VDAG_01630

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_01630	EGY17948	EGY17948

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.80e-74	249.6	720	1092

Active Site

Position(s)	Description	Evidence
1060	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp....................ehlklFeflGrl 77
           +lk+ ++++f +     E+g+d gGv++efl   +++++ ++     + en+++ ++pnp  +   +                       + +eflGrl
   Q: 720  SLKEPVQIQFIDsfgdvEAGIDGGGVAKEFLLSAINQVFMNQSDDRYFVENSQKLWYPNPIIFD--KfreetekmglpeaekkdiltGLSQRYEFLGRL 816
           6788899999999999***************999999987775544567778888888887663..345788999999999999999999********* PP
   S: 78   lgkalqdgrlldlplsksfyklllgk........klsledleevdpelykslkeikenaesdieelgldltfs.vseei....lgetkeeeLkpgGeni 163
           +gk+++++ l+d++++ +f+ +            + +++dl ++d+ ly+ l  +k++  +++e l+ld+t++ +  +     + + + +eL+pg  ++
   Q: 817  VGKCMYEDILIDVNFAGFFLLKWAASgltgeesyRGNVNDLRDLDAGLYQGLVHLKNLPADEVESLSLDFTVDdQ-ISAdgetVRSLT-TELIPGRGST 913
           ********************99977767777777799*********************99999999999988841.322344244444.45******** PP
   S: 164  pVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky.....kggytedspaiqwFwevleef 256
           pVt++N+  Y++ ++ +rl  + ++q+ af +G++ +i +++ls+F++ el+ l+ G+ +ei+++dl+++t+y      g+  e++p+iq Fw+v+++f
   Q: 914  PVTKDNRLLYISYMARHRLVVQPAQQTMAFLRGLRAIIAPTWLSMFNQTELQRLVGGDsSEISIDDLRANTNYsglyvIGDDGEEHPTIQLFWKVVRGF 1012
           *************************************************************************76666445579*************** PP
   S: 257  sseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           ++ +r+++L++vT+++r+Pl Gf +l+p lf ir+ ++d +rlPs++TC+n+LkLP+Y+ +e+l++kL +Ai++++gF+ls
   Q: 1013 TDAQRRDLLKYVTSTPRAPLLGFGSLNP-LFSIRDGGTDeARLPSASTCVNLLKLPRYTDEETLRRKLVLAISSGAGFDLS 1092
           ***************************5.6*****66666**************************************985 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MHSTFTGNSR RTRNVNLSGQ NQNPFANVWS PSASSGASKT VSNAQAERQQ RQLERDRLKA 60
ARNIQRTWRS HHVRRQCRDV WRQAFDDIYR VDTPNTAVQR VHTALPLLLA AFQRNRPDDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACCAGAGG AGCTCCCATT TGGAGAGTGC CCCGCCACGA TCCCAGACTT TCGAATAGCT 60
ATCCTTTGGT TGCCCGAGAC TCGCTGAAGT TGGCATGTCT GTCCAAGTCA ATCTCCTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

vda:VDAG_01630

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.63	3.00e-71	262.00
IUUC-Aml-001355	Ailuropoda melanoleuca	34.56	4.00e-82	298.00
IUUC-Atr-003017	Amborella trichopoda	33.50	6.00e-74	271.00
IUUC-Apl-003731	Anas platyrhynchos	38.60	7.00e-82	297.00
IUUC-Aca-005248	Anolis carolinensis	38.38	3.00e-81	295.00
IUUC-Aly-005794	Arabidopsis lyrata	36.30	8.00e-72	263.00
IUUC-Ath-007269	Arabidopsis thaliana	36.74	2.00e-74	272.00
IUUC-Ago-007748	Ashbya gossypii	38.24	2.00e-76	279.00
IUUC-Acl-008158	Aspergillus clavatus	45.56	2.00e-177	615.00
IUUC-Afl-008398	Aspergillus flavus	46.42	0.00e+00	632.00
IUUC-Afu-008937	Aspergillus fumigatus	46.24	0.00e+00	639.00
IUUC-Ani-009252	Aspergillus nidulans	47.74	0.00e+00	666.00
IUUC-Ang-009773	Aspergillus niger	45.27	0.00e+00	631.00
IUUC-Aor-009940	Aspergillus oryzae	46.42	0.00e+00	632.00
IUUC-Ate-010395	Aspergillus terreus	47.32	0.00e+00	637.00
IUUC-Ame-010769	Astyanax mexicanus	35.93	5.00e-58	217.00
IUUC-Bgr-012269	Blumeria graminis	58.91	2.00e-146	510.00
IUUC-Bta-012841	Bos taurus	34.74	4.00e-84	304.00
IUUC-Bci-013743	Botrytis cinerea	46.81	0.00e+00	718.00
IUUC-Bdi-014502	Brachypodium distachyon	36.42	6.00e-72	264.00
IUUC-Bol-015093	Brassica oleracea	36.13	5.00e-74	271.00
IUUC-Bra-016722	Brassica rapa	35.91	9.00e-74	270.00
IUUC-Cel-018447	Caenorhabditis elegans	31.82	3.00e-51	195.00
IUUC-Cja-019743	Callithrix jacchus	34.28	5.00e-82	297.00
IUUC-Cfa-021031	Canis familiaris	34.56	1.00e-82	300.00
IUUC-Cpo-022401	Cavia porcellus	34.56	2.00e-82	299.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	34.61	1.00e-57	215.00
IUUC-Csa-024107	Chlorocebus sabaeus	34.74	4.00e-84	304.00
IUUC-Cho-024750	Choloepus hoffmanni	40.32	2.00e-72	266.00
IUUC-Cin-025750	Ciona intestinalis	30.37	2.00e-56	212.00
IUUC-Csv-026016	Ciona savignyi	33.06	7.00e-63	234.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	60.31	0.00e+00	992.00
IUUC-Cne-026841	Cryptococcus neoformans	35.88	9.00e-84	303.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.04	2.00e-76	278.00
IUUC-Dre-028196	Danio rerio	38.24	6.00e-79	287.00
IUUC-Dno-029024	Dasypus novemcinctus	34.56	6.00e-83	300.00
IUUC-Dor-030938	Dipodomys ordii	35.71	8.00e-61	227.00
IUUC-Dse-031416	Dothistroma septosporum	45.98	0.00e+00	641.00
IUUC-Dme-031946	Drosophila melanogaster	38.02	2.00e-73	269.00
IUUC-Ete-033041	Echinops telfairi	31.78	2.00e-41	162.00
IUUC-Eca-033828	Equus caballus	34.74	8.00e-84	303.00
IUUC-Eeu-035201	Erinaceus europaeus	32.06	1.00e-40	159.00
IUUC-Fca-035907	Felis catus	34.74	1.00e-82	299.00
IUUC-Fal-037389	Ficedula albicollis	38.60	2.00e-81	295.00
IUUC-Fox-037788	Fusarium oxysporum	53.07	0.00e+00	833.00
IUUC-Fso-038088	Fusarium solani	52.42	0.00e+00	781.00
IUUC-Gmo-039412	Gadus morhua	33.54	6.00e-63	234.00
IUUC-Ggr-039941	Gaeumannomyces graminis	51.32	0.00e+00	767.00
IUUC-Gga-040310	Gallus gallus	38.38	4.00e-81	295.00
IUUC-Gac-042088	Gasterosteus aculeatus	33.54	7.00e-64	237.00
IUUC-Gma-042728	Glycine max	37.91	4.00e-73	268.00
IUUC-Ggo-045031	Gorilla gorilla	34.56	1.00e-83	303.00
IUUC-Hsa-045880	Homo sapiens	34.56	1.00e-83	303.00
IUUC-Hvu-047102	Hordeum vulgare	36.63	6.00e-71	261.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	35.48	6.00e-61	226.00
IUUC-Kpa-049307	Komagataella pastoris	30.43	5.00e-70	257.00
IUUC-Lch-050664	Latimeria chalumnae	33.82	1.00e-63	236.00
IUUC-Lpe-050755	Leersia perrieri	36.62	5.00e-71	261.00
IUUC-Loc-052218	Lepisosteus oculatus	32.99	4.00e-78	284.00
IUUC-Lma-053096	Leptosphaeria maculans	45.11	0.00e+00	651.00
IUUC-Laf-053902	Loxodonta africana	33.19	3.00e-63	235.00
IUUC-Mcc-055127	Macaca mulatta	34.56	1.00e-83	303.00
IUUC-Meu-056527	Macropus eugenii	39.23	5.00e-51	194.00
IUUC-Mor-057021	Magnaporthe oryzae	49.58	0.00e+00	743.00
IUUC-Mpo-057570	Magnaporthe poae	51.08	0.00e+00	737.00
IUUC-Mtr-057671	Medicago truncatula	37.15	2.00e-73	269.00
IUUC-Mla-059124	Melampsora laricipopulina	40.37	2.00e-91	327.00
IUUC-Mga-059581	Meleagris gallopavo	38.60	2.00e-81	295.00
IUUC-Mvi-060445	Microbotryum violaceum	35.98	3.00e-108	384.00
IUUC-Mmr-061360	Microcebus murinus	34.74	1.00e-83	302.00
IUUC-Mdo-062194	Monodelphis domestica	38.82	2.00e-81	296.00
IUUC-Mmu-064189	Mus musculus	34.39	1.00e-82	299.00
IUUC-Mac-064989	Musa acuminata	37.26	6.00e-73	267.00
IUUC-Mpu-066439	Mustela putorius furo	34.74	3.00e-83	301.00
IUUC-Mlu-068228	Myotis lucifugus	34.74	5.00e-83	301.00
IUUC-Nfi-068280	Neosartorya fischeri	46.95	0.00e+00	635.00
IUUC-Ncr-068869	Neurospora crassa	48.83	0.00e+00	749.00
IUUC-Nle-069687	Nomascus leucogenys	34.27	1.00e-83	302.00
IUUC-Opr-070554	Ochotona princeps	33.19	9.00e-63	233.00
IUUC-Ont-071836	Oreochromis niloticus	33.33	2.00e-80	292.00
IUUC-Oan-072800	Ornithorhynchus anatinus	38.60	6.00e-82	297.00
IUUC-Ocu-074587	Oryctolagus cuniculus	34.74	2.00e-83	302.00
IUUC-Oba-075006	Oryza barthii	37.45	9.00e-71	260.00
IUUC-Obr-076320	Oryza brachyantha	37.26	6.00e-73	267.00
IUUC-Ogl-077093	Oryza glaberrima	36.83	4.00e-72	265.00
IUUC-Ogu-078947	Oryza glumaepatula	37.45	8.00e-71	260.00
IUUC-Oin-080058	Oryza indica	36.83	5.00e-72	264.00
IUUC-Olo-080742	Oryza longistaminata	36.83	6.00e-72	264.00
IUUC-Ome-081741	Oryza meridionalis	36.28	2.00e-66	245.00
IUUC-Oni-082385	Oryza nivara	37.45	9.00e-71	260.00
IUUC-Opu-083529	Oryza punctata	37.04	2.00e-72	265.00
IUUC-Oru-085128	Oryza rufipogon	34.60	6.00e-62	231.00
IUUC-Osa-085557	Oryza sativa	36.83	1.00e-71	262.00
IUUC-Ola-087209	Oryzias latipes	37.42	4.00e-79	288.00
IUUC-Olu-087699	Ostreococcus lucimarinus	36.63	5.00e-57	213.00
IUUC-Oga-088776	Otolemur garnettii	34.56	9.00e-83	300.00
IUUC-Oar-089441	Ovis aries	34.74	3.00e-84	305.00
IUUC-Ptr-091273	Pan troglodytes	34.56	1.00e-83	303.00
IUUC-Pan-091981	Papio anubis	34.56	1.00e-83	302.00
IUUC-Psi-093251	Pelodiscus sinensis	32.35	5.00e-52	197.00
IUUC-Pma-094738	Petromyzon marinus	38.82	1.00e-78	286.00
IUUC-Pno-095132	Phaeosphaeria nodorum	43.35	8.00e-163	565.00
IUUC-Ppa-095682	Physcomitrella patens	37.01	4.00e-73	268.00
IUUC-Pfo-097511	Poecilia formosa	33.51	7.00e-81	293.00
IUUC-Pab-098634	Pongo abelii	31.58	1.00e-68	253.00
IUUC-Pop-098928	Populus trichocarpa	37.09	2.00e-62	233.00
IUUC-Pca-100987	Procavia capensis	38.22	7.00e-75	273.00
IUUC-Ppe-101281	Prunus persica	35.78	1.00e-70	259.00
IUUC-Pva-103034	Pteropus vampyrus	32.11	2.00e-69	255.00
IUUC-Pgr-103513	Puccinia graminis	37.89	3.00e-99	354.00
IUUC-Ptt-103967	Puccinia triticina	39.61	2.00e-88	318.00
IUUC-Pte-104105	Pyrenophora teres	45.82	0.00e+00	671.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	46.27	0.00e+00	668.00
IUUC-Rno-106028	Rattus norvegicus	30.08	2.00e-46	179.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.44	7.00e-81	293.00
IUUC-Sha-107108	Sarcophilus harrisii	36.18	4.00e-72	264.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	30.16	9.00e-89	320.00
IUUC-Spo-108097	Schizosaccharomyces pombe	37.04	8.00e-93	333.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	47.22	0.00e+00	718.00
IUUC-Smo-109007	Selaginella moellendorffii	37.45	3.00e-73	268.00
IUUC-Sit-110457	Setaria italica	36.88	1.00e-63	236.00
IUUC-Sly-111362	Solanum lycopersicum	38.15	2.00e-69	255.00
IUUC-Sar-113687	Sorex araneus	31.31	4.00e-35	141.00
IUUC-Sbi-114433	Sorghum bicolor	32.72	1.00e-71	263.00
IUUC-Sre-115038	Sporisorium reilianum	42.74	2.00e-92	332.00
IUUC-Ssc-116103	Sus scrofa	33.61	4.00e-63	234.00
IUUC-Tgu-116729	Taeniopygia guttata	38.60	7.00e-82	297.00
IUUC-Tru-118068	Takifugu rubripes	37.86	2.00e-78	286.00
IUUC-Tsy-118942	Tarsius syrichta	44.85	7.00e-60	224.00
IUUC-Tni-120732	Tetraodon nigroviridis	37.86	8.00e-74	270.00
IUUC-Tca-121770	Theobroma cacao	36.23	3.00e-72	265.00
IUUC-Tre-121892	Trichoderma reesei	53.18	0.00e+00	840.00
IUUC-Tvi-122354	Trichoderma virens	54.31	0.00e+00	842.00
IUUC-Tae-125466	Triticum aestivum	37.09	2.00e-68	252.00
IUUC-Tur-126086	Triticum urartu	36.63	3.00e-71	262.00
IUUC-Tme-127102	Tuber melanosporum	42.96	2.00e-167	581.00
IUUC-Tbe-127351	Tupaia belangeri	36.09	2.00e-61	228.00
IUUC-Ttr-129061	Tursiops truncatus	37.99	1.00e-74	273.00
IUUC-Uma-129343	Ustilago maydis	36.16	2.00e-104	372.00
IUUC-Vvi-131234	Vitis vinifera	36.74	4.00e-64	238.00
IUUC-Xtr-132094	Xenopus tropicalis	37.50	9.00e-79	286.00
IUUC-Xma-133923	Xiphophorus maculatus	33.51	7.00e-81	293.00
IUUC-Yli-134496	Yarrowia lipolytica	37.07	2.00e-88	318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence