iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059698

UUCD1 version

UUC-MeG-00451

Ensembl Protein ID

ENSMGAP00000010334.2

UniProt Accession

G1NC88; G1NC88_MELGA

Protein Name

Uncharacterized protein

Gene Name

UBR2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000009946.2	ENSMGAT00000011187.2	ENSMGAP00000010334.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.20e-39	134.1	200	275
E3 activity/RING/RING	2.00e-09	37.6	1082	1187
E3 activity/N-recognin/UBR-box	1.90e-31	108.1	71	141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++Gd+++c++ak++i++n++++++ pLkV+v
   Q: 200  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCDQAKSVIVRNTSRQTK-PLKVQV 275
           9*********************************************************************.****98 PP

E3 activity/RING/RING

   S: 1    CaiCledf............................................kdgplvlpCgHvfhadClqkw.............. 29
           C++C+e+                                             ++g+++++CgH++ha+C+q++              
   Q: 1082 CILCQEEQevkvdsramvlaafiqrstvlsknrnriipdpekhdplfmhpdlSCGTHTGSCGHIMHAHCWQRYfdavqakeqrrqqr 1168
           888855554444433333333333333333333333333333222333333355899****************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + +++++++ef+CPlC
   Q: 1169 lrvHTSYDVENGEFLCPLC 1187
           ******************* PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  ++H++H+y++++sggggfCdCGdteAw++g++C+k++
   Q: 71   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHREHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHE 141
           68******************************************************************996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

KWLQANELQK EVYQHLAYYV PKIYCRGPNP APQREDMLAQ HVLLGPMEWY LCGEDPAFGF 60
PKLEQANKPS HLCGRVFKVG EPTYSCRDCA VDPTCVLCME CFLGSIHREH RYRMTTSGGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATGGCTGC AAGCAAATGA GCTTCAGAAG GAAGTATACC AGCATCTGGC CTACTATGTA 60
CCAAAAATTT ACTGCAGGGG TCCTAACCCT GCCCCACAGA GAGAAGACAT GCTGGCACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000785--C:chromatin
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	27.32	4.00e-21	97.80
IUUC-Aml-001876	Ailuropoda melanoleuca	79.21	0.00e+00	2561.00
IUUC-Atr-002501	Amborella trichopoda	29.72	3.00e-28	121.00
IUUC-Apl-003828	Anas platyrhynchos	97.22	0.00e+00	3348.00
IUUC-Aca-005189	Anolis carolinensis	88.03	0.00e+00	3095.00
IUUC-Aly-005901	Arabidopsis lyrata	31.46	1.00e-25	113.00
IUUC-Ath-007148	Arabidopsis thaliana	30.05	2.00e-24	108.00
IUUC-Ago-007946	Ashbya gossypii	22.23	2.00e-27	119.00
IUUC-Acl-008055	Aspergillus clavatus	25.71	2.00e-34	141.00
IUUC-Afl-008479	Aspergillus flavus	23.58	1.00e-46	182.00
IUUC-Afu-008929	Aspergillus fumigatus	24.11	2.00e-53	205.00
IUUC-Ani-009334	Aspergillus nidulans	24.52	6.00e-50	193.00
IUUC-Ang-009550	Aspergillus niger	24.16	1.00e-47	186.00
IUUC-Aor-010124	Aspergillus oryzae	23.58	1.00e-46	182.00
IUUC-Ame-011917	Astyanax mexicanus	75.49	0.00e+00	2517.00
IUUC-Bta-012768	Bos taurus	87.29	0.00e+00	3026.00
IUUC-Bdi-014635	Brachypodium distachyon	25.71	2.00e-29	125.00
IUUC-Bol-015669	Brassica oleracea	30.39	6.00e-30	127.00
IUUC-Bra-017776	Brassica rapa	30.14	2.00e-29	125.00
IUUC-Cel-018476	Caenorhabditis elegans	30.82	8.00e-81	296.00
IUUC-Cja-019797	Callithrix jacchus	88.07	0.00e+00	2417.00
IUUC-Cfa-020950	Canis familiaris	89.25	0.00e+00	3080.00
IUUC-Cpo-022385	Cavia porcellus	87.51	0.00e+00	3050.00
IUUC-Csa-024082	Chlorocebus sabaeus	89.08	0.00e+00	3077.00
IUUC-Cho-025029	Choloepus hoffmanni	81.22	0.00e+00	2003.00
IUUC-Cin-025148	Ciona intestinalis	36.24	6.00e-140	491.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	23.99	7.00e-58	219.00
IUUC-Cne-026823	Cryptococcus neoformans	22.88	1.00e-36	149.00
IUUC-Dre-028343	Danio rerio	74.58	0.00e+00	2537.00
IUUC-Dno-030002	Dasypus novemcinctus	86.41	0.00e+00	1843.00
IUUC-Dor-030207	Dipodomys ordii	75.67	0.00e+00	1508.00
IUUC-Dse-031531	Dothistroma septosporum	25.20	1.00e-56	216.00
IUUC-Ete-033162	Echinops telfairi	81.61	0.00e+00	1332.00
IUUC-Eca-033454	Equus caballus	87.93	0.00e+00	3046.00
IUUC-Eeu-034783	Erinaceus europaeus	72.92	0.00e+00	1430.00
IUUC-Fca-036588	Felis catus	88.63	0.00e+00	3056.00
IUUC-Fal-036919	Ficedula albicollis	94.55	0.00e+00	3246.00
IUUC-Fox-037984	Fusarium oxysporum	25.27	3.00e-40	161.00
IUUC-Fso-038463	Fusarium solani	24.58	3.00e-46	181.00
IUUC-Gmo-039698	Gadus morhua	71.84	0.00e+00	1655.00
IUUC-Ggr-040070	Gaeumannomyces graminis	24.44	3.00e-46	181.00
IUUC-Gga-041123	Gallus gallus	98.90	0.00e+00	3407.00
IUUC-Gac-042622	Gasterosteus aculeatus	68.51	0.00e+00	2246.00
IUUC-Ggo-045583	Gorilla gorilla	87.53	0.00e+00	3043.00
IUUC-Hsa-046343	Homo sapiens	89.42	0.00e+00	3088.00
IUUC-Hvu-047626	Hordeum vulgare	28.98	5.00e-27	116.00
IUUC-Kpa-049088	Komagataella pastoris	21.80	2.00e-47	185.00
IUUC-Lch-049649	Latimeria chalumnae	77.77	0.00e+00	2640.00
IUUC-Loc-052818	Lepisosteus oculatus	76.63	0.00e+00	2650.00
IUUC-Lma-053059	Leptosphaeria maculans	23.07	2.00e-49	191.00
IUUC-Laf-054142	Loxodonta africana	88.39	0.00e+00	3062.00
IUUC-Mcc-055677	Macaca mulatta	88.84	0.00e+00	3063.00
IUUC-Meu-056204	Macropus eugenii	67.93	0.00e+00	733.00
IUUC-Mor-057051	Magnaporthe oryzae	23.94	1.00e-44	175.00
IUUC-Mpo-057372	Magnaporthe poae	26.37	4.00e-48	187.00
IUUC-Mtr-058538	Medicago truncatula	30.04	2.00e-27	118.00
IUUC-Mla-058963	Melampsora laricipopulina	24.68	1.00e-54	209.00
IUUC-Mvi-060535	Microbotryum violaceum	24.66	5.00e-50	193.00
IUUC-Mmr-060901	Microcebus murinus	86.36	0.00e+00	2981.00
IUUC-Mdo-062014	Monodelphis domestica	90.81	0.00e+00	3157.00
IUUC-Mmu-063699	Mus musculus	85.26	0.00e+00	2952.00
IUUC-Mpu-066153	Mustela putorius furo	89.08	0.00e+00	3075.00
IUUC-Mlu-068151	Myotis lucifugus	87.75	0.00e+00	3019.00
IUUC-Nfi-068403	Neosartorya fischeri	23.56	6.00e-51	196.00
IUUC-Ncr-068864	Neurospora crassa	23.29	4.00e-44	174.00
IUUC-Nle-069529	Nomascus leucogenys	89.13	0.00e+00	3080.00
IUUC-Opr-071107	Ochotona princeps	80.58	0.00e+00	1242.00
IUUC-Ont-072189	Oreochromis niloticus	67.33	0.00e+00	2194.00
IUUC-Oan-072893	Ornithorhynchus anatinus	89.42	0.00e+00	3093.00
IUUC-Ocu-074082	Oryctolagus cuniculus	87.15	0.00e+00	3014.00
IUUC-Ola-087460	Oryzias latipes	65.67	0.00e+00	2173.00
IUUC-Olu-087832	Ostreococcus lucimarinus	28.33	1.60e-02	34.70
IUUC-Oga-088432	Otolemur garnettii	88.73	0.00e+00	3089.00
IUUC-Oar-090206	Ovis aries	86.37	0.00e+00	3010.00
IUUC-Ptr-091180	Pan troglodytes	87.80	0.00e+00	3043.00
IUUC-Pan-092375	Papio anubis	89.02	0.00e+00	3077.00
IUUC-Psi-093049	Pelodiscus sinensis	92.14	0.00e+00	3164.00
IUUC-Pno-094877	Phaeosphaeria nodorum	22.47	2.00e-43	171.00
IUUC-Pfo-096524	Poecilia formosa	64.82	0.00e+00	2078.00
IUUC-Pab-097989	Pongo abelii	87.46	0.00e+00	2998.00
IUUC-Pop-099184	Populus trichocarpa	31.48	4.00e-11	62.00
IUUC-Pca-100207	Procavia capensis	74.91	0.00e+00	1171.00
IUUC-Ppe-101802	Prunus persica	28.52	9.00e-26	113.00
IUUC-Pgr-103372	Puccinia graminis	24.38	1.00e-50	196.00
IUUC-Ptt-103878	Puccinia triticina	24.15	3.00e-47	184.00
IUUC-Rno-105567	Rattus norvegicus	84.00	0.00e+00	2878.00
IUUC-Sce-106272	Saccharomyces cerevisiae	21.04	2.00e-26	115.00
IUUC-Sha-106980	Sarcophilus harrisii	90.38	0.00e+00	3061.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	23.92	6.00e-50	193.00
IUUC-Spo-108183	Schizosaccharomyces pombe	24.95	8.00e-53	202.00
IUUC-Smo-108719	Selaginella moellendorffii	31.54	2.00e-29	125.00
IUUC-Sly-111286	Solanum lycopersicum	30.25	2.00e-26	115.00
IUUC-Sar-113332	Sorex araneus	81.00	0.00e+00	2041.00
IUUC-Sbi-114577	Sorghum bicolor	27.17	5.00e-29	124.00
IUUC-Ssc-115525	Sus scrofa	88.74	0.00e+00	2362.00
IUUC-Tgu-116943	Taeniopygia guttata	96.99	0.00e+00	3352.00
IUUC-Tru-117673	Takifugu rubripes	66.53	0.00e+00	2205.00
IUUC-Tsy-119032	Tarsius syrichta	88.06	0.00e+00	1741.00
IUUC-Tni-119987	Tetraodon nigroviridis	67.22	0.00e+00	2180.00
IUUC-Tca-121077	Theobroma cacao	32.70	2.00e-26	115.00
IUUC-Tre-122137	Trichoderma reesei	24.30	3.00e-60	228.00
IUUC-Tvi-122272	Trichoderma virens	23.25	9.00e-56	213.00
IUUC-Tur-126562	Triticum urartu	28.21	3.00e-27	117.00
IUUC-Tme-127156	Tuber melanosporum	23.98	2.00e-52	202.00
IUUC-Tbe-128103	Tupaia belangeri	81.64	0.00e+00	1162.00
IUUC-Ttr-128253	Tursiops truncatus	82.72	0.00e+00	2818.00
IUUC-Vda-129778	Verticillium dahliae	24.23	4.00e-49	190.00
IUUC-Vpa-130540	Vicugna pacos	84.22	0.00e+00	2754.00
IUUC-Xtr-132690	Xenopus tropicalis	82.97	0.00e+00	2897.00
IUUC-Xma-133748	Xiphophorus maculatus	65.26	0.00e+00	2029.00
IUUC-Yli-134662	Yarrowia lipolytica	25.23	9.00e-33	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence