iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050107

Ensembl Protein ID

ENSLACP00000012174.1

UniProt Accession

H3ARA3; H3ARA3_LATCH

Genbank Protein ID

ENSLACP00000012174

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01114209

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010714.1	ENSLACT00000012266.1	ENSLACP00000012174.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-117	392.4	289	934
ULD/UDP/UBQ/UBQ_Other	7.50e-07	29.2	151	216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++e++n +np ++ ge+++s+++l++++w+++ ++v+pr+++++++++a++fsgy+
   Q: 289  CGLSNLGNTCFMNSAVQCLSNTPPLTEYFLNdKYEEEMNYDNPLGMRGEIARSYAELIKQMWSGRYSYVTPRAFKTQVGRFAPQFSGYQ 377
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c++c +vs++++pf++l
   Q: 378  QQDSQELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHIKRNDSIIVDIFHGLFKSTLVCPKCFKVSVTFDPFCYL 464
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 465  TLPLPMKKERTLEvflvrmdpltkpmqykvivpkignildlcaalrtlsgistdrmivtdiynhrfhrifsmdenlssimerddiyvfe 553
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 554  vavnrteetdqvvipvylrekhrqtayshhsgstlfgqpflitvprnisedklynhlllrmcryvktcteseeveetlhcckdnningn 642
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 643  spngvheegspsemetdeqddesihdqelfsenensqsedsvggdnssengicsdntckgqnflgykkrlftfqfnnlgntdfsyikdd 731
           ***************************************************************************************** PP
   S: 186  ........................................................slqdcLesftkeeelegenkyycekckkkqeae 218
                                                                   +l+dc+e ft++e+l  e+ +yc++ck++q+a+
   Q: 732  trqirfddrhlrldersylaldwdpevkkryfddnaaedfekhesveykpqkkafvKLKDCIELFTTKEKLGAEDPWYCPNCKQHQQAT 820
           ***************************************************************************************** PP
   S: 219  kklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk. 305
           kkl+l++lP+vL++hLkRfs+s+  ++r k+++ v fp++ Ld+s+f+++p+ +   + +Y+Liav +H+G++++GHY+a++kn+++  
   Q: 821  KKLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVVFPITdLDMSEFLINPNAG---PSRYNLIAVSNHYGGMGGGHYTAFAKNKDDTk 904
           *******************9977..6999*********************9988...89*************************76656 PP
   S: 306  WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           W++fdDs+V++ +e+++++   + aYvlfY+r+
   Q: 905  WYNFDDSSVSSASEDQIVS---KAAYVLFYQRQ 934
           *******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekks 74
           +++++dt+  + ++++k++ ip + + rL++k      ++L ++d t++d gl++g+++++++k++
   Q: 151  RFSKADTIDSIEKEMRKLFTIPdEKETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNE 216
           4899******************999*****998875544569********************9986 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAEGGAAELE TQRTEIAALL KTPLRRGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGEQNV 60
YPGPVDNSGL LKDDDPQSLK EHLIDELDYI LVPIEGWNKL ISWYALTESQ EPIARKVVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAATGCTG CGGGATCTGA TTGGGGAAGA TGGCGGAGGG AGGAGCGGCT GAGCTGGAGA 60
CCCAGCGAAC AGAGATCGCT GCACTGTTAA AAACTCCGCT CAGGAGAGGG GACACCTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001852	Ailuropoda melanoleuca	86.18	0.00e+00	1695.00
IUUC-Atr-002955	Amborella trichopoda	40.99	9.00e-125	441.00
IUUC-Apl-003249	Anas platyrhynchos	87.09	0.00e+00	1614.00
IUUC-Aca-004261	Anolis carolinensis	85.96	0.00e+00	1623.00
IUUC-Aly-005644	Arabidopsis lyrata	36.25	8.00e-138	484.00
IUUC-Ath-007560	Arabidopsis thaliana	36.47	2.00e-146	513.00
IUUC-Acl-008284	Aspergillus clavatus	33.82	9.00e-57	216.00
IUUC-Afl-008507	Aspergillus flavus	34.79	1.00e-56	215.00
IUUC-Afu-008878	Aspergillus fumigatus	32.23	2.00e-58	222.00
IUUC-Ang-009562	Aspergillus niger	34.44	2.00e-56	215.00
IUUC-Aor-009949	Aspergillus oryzae	34.58	7.00e-56	212.00
IUUC-Ame-010757	Astyanax mexicanus	80.22	0.00e+00	1297.00
IUUC-Bta-013128	Bos taurus	83.83	0.00e+00	1673.00
IUUC-Bdi-014013	Brachypodium distachyon	35.68	4.00e-148	518.00
IUUC-Bol-015570	Brassica oleracea	37.88	2.00e-153	536.00
IUUC-Bra-016885	Brassica rapa	36.32	6.00e-153	535.00
IUUC-Cel-018257	Caenorhabditis elegans	31.99	4.00e-90	326.00
IUUC-Cja-019222	Callithrix jacchus	86.37	0.00e+00	1699.00
IUUC-Cfa-020035	Canis familiaris	86.18	0.00e+00	1696.00
IUUC-Cpo-022071	Cavia porcellus	86.66	0.00e+00	1626.00
IUUC-Csa-023882	Chlorocebus sabaeus	86.67	0.00e+00	1704.00
IUUC-Cho-024875	Choloepus hoffmanni	80.45	0.00e+00	805.00
IUUC-Cin-025292	Ciona intestinalis	43.71	0.00e+00	743.00
IUUC-Csv-026109	Ciona savignyi	42.74	0.00e+00	692.00
IUUC-Cne-026852	Cryptococcus neoformans	39.89	8.00e-73	269.00
IUUC-Dno-029025	Dasypus novemcinctus	82.00	0.00e+00	1606.00
IUUC-Dor-030956	Dipodomys ordii	79.70	0.00e+00	1459.00
IUUC-Dse-031432	Dothistroma septosporum	33.75	8.00e-58	219.00
IUUC-Eca-034340	Equus caballus	86.78	0.00e+00	1652.00
IUUC-Eeu-034488	Erinaceus europaeus	78.50	0.00e+00	1137.00
IUUC-Fca-035552	Felis catus	83.62	0.00e+00	1664.00
IUUC-Fal-036618	Ficedula albicollis	87.20	0.00e+00	1611.00
IUUC-Fox-037986	Fusarium oxysporum	30.14	3.00e-66	247.00
IUUC-Fso-038291	Fusarium solani	30.05	9.00e-67	249.00
IUUC-Gga-041146	Gallus gallus	86.47	0.00e+00	1659.00
IUUC-Gac-041679	Gasterosteus aculeatus	78.95	0.00e+00	1484.00
IUUC-Gma-043077	Glycine max	36.30	6.00e-154	538.00
IUUC-Ggo-045002	Gorilla gorilla	86.90	0.00e+00	1651.00
IUUC-Hsa-046052	Homo sapiens	86.67	0.00e+00	1705.00
IUUC-Hvu-047108	Hordeum vulgare	38.81	3.00e-122	432.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	84.26	0.00e+00	1676.00
IUUC-Kpa-049332	Komagataella pastoris	31.74	3.00e-69	256.00
IUUC-Lpe-050892	Leersia perrieri	33.20	6.00e-127	448.00
IUUC-Loc-052105	Lepisosteus oculatus	83.18	0.00e+00	1545.00
IUUC-Lma-052981	Leptosphaeria maculans	33.40	5.00e-66	247.00
IUUC-Laf-053645	Loxodonta africana	86.18	0.00e+00	1696.00
IUUC-Mcc-055586	Macaca mulatta	86.67	0.00e+00	1705.00
IUUC-Meu-056764	Macropus eugenii	80.48	0.00e+00	924.00
IUUC-Mor-056985	Magnaporthe oryzae	41.07	3.00e-60	228.00
IUUC-Mtr-058138	Medicago truncatula	36.68	6.00e-157	548.00
IUUC-Mla-058848	Melampsora laricipopulina	31.88	3.00e-75	277.00
IUUC-Mga-060162	Meleagris gallopavo	86.67	0.00e+00	1662.00
IUUC-Mvi-060324	Microbotryum violaceum	39.64	8.00e-73	269.00
IUUC-Mmr-061105	Microcebus murinus	86.67	0.00e+00	1705.00
IUUC-Mdo-062107	Monodelphis domestica	86.98	0.00e+00	1698.00
IUUC-Mmu-063662	Mus musculus	85.55	0.00e+00	1681.00
IUUC-Mac-065239	Musa acuminata	34.34	1.00e-132	467.00
IUUC-Mpu-065868	Mustela putorius furo	84.45	0.00e+00	1687.00
IUUC-Mlu-068000	Myotis lucifugus	81.72	0.00e+00	1514.00
IUUC-Nfi-068330	Neosartorya fischeri	32.56	5.00e-58	220.00
IUUC-Nle-069874	Nomascus leucogenys	87.05	0.00e+00	1686.00
IUUC-Opr-071212	Ochotona princeps	82.62	0.00e+00	1593.00
IUUC-Ont-071834	Oreochromis niloticus	80.74	0.00e+00	1480.00
IUUC-Ocu-074573	Oryctolagus cuniculus	86.88	0.00e+00	1708.00
IUUC-Oba-075427	Oryza barthii	34.03	7.00e-130	457.00
IUUC-Obr-076416	Oryza brachyantha	39.81	2.00e-121	429.00
IUUC-Ogl-077583	Oryza glaberrima	38.44	4.00e-124	439.00
IUUC-Ogu-078422	Oryza glumaepatula	34.03	4.00e-130	458.00
IUUC-Oin-079300	Oryza indica	38.59	5.00e-125	442.00
IUUC-Olo-080315	Oryza longistaminata	35.78	5.00e-142	498.00
IUUC-Ome-081271	Oryza meridionalis	36.00	4.00e-146	511.00
IUUC-Oni-082834	Oryza nivara	34.13	1.00e-130	460.00
IUUC-Opu-083691	Oryza punctata	35.02	5.00e-143	501.00
IUUC-Oru-084820	Oryza rufipogon	34.03	4.00e-130	458.00
IUUC-Osa-086139	Oryza sativa	35.77	1.00e-145	510.00
IUUC-Ola-086553	Oryzias latipes	57.92	0.00e+00	1098.00
IUUC-Olu-087717	Ostreococcus lucimarinus	48.76	2.00e-84	306.00
IUUC-Oga-089022	Otolemur garnettii	83.93	0.00e+00	1670.00
IUUC-Oar-089767	Ovis aries	85.86	0.00e+00	1692.00
IUUC-Ptr-091319	Pan troglodytes	84.44	0.00e+00	1683.00
IUUC-Pan-091968	Papio anubis	86.67	0.00e+00	1704.00
IUUC-Psi-093849	Pelodiscus sinensis	86.36	0.00e+00	1627.00
IUUC-Pma-094533	Petromyzon marinus	59.45	0.00e+00	1104.00
IUUC-Pno-094890	Phaeosphaeria nodorum	31.58	1.00e-58	222.00
IUUC-Pfo-097110	Poecilia formosa	79.75	0.00e+00	1485.00
IUUC-Pab-098664	Pongo abelii	86.67	0.00e+00	1704.00
IUUC-Pop-099801	Populus trichocarpa	36.29	5.00e-150	525.00
IUUC-Pca-100359	Procavia capensis	70.18	0.00e+00	1172.00
IUUC-Ppe-101587	Prunus persica	37.50	5.00e-149	521.00
IUUC-Pva-102394	Pteropus vampyrus	84.74	0.00e+00	1658.00
IUUC-Pgr-103546	Puccinia graminis	29.45	2.00e-69	258.00
IUUC-Pte-104102	Pyrenophora teres	31.99	5.00e-57	217.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	38.22	1.00e-57	219.00
IUUC-Rno-105383	Rattus norvegicus	83.93	0.00e+00	1667.00
IUUC-Sce-106170	Saccharomyces cerevisiae	38.04	9.00e-63	235.00
IUUC-Sha-107393	Sarcophilus harrisii	86.88	0.00e+00	1702.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	33.89	4.00e-81	296.00
IUUC-Spo-108291	Schizosaccharomyces pombe	44.24	4.00e-73	270.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	28.89	5.00e-12	66.20
IUUC-Sit-109948	Setaria italica	36.64	7.00e-141	494.00
IUUC-Sly-111746	Solanum lycopersicum	36.84	2.00e-152	533.00
IUUC-Stu-112671	Solanum tuberosum	36.31	1.00e-150	526.00
IUUC-Sar-113498	Sorex araneus	86.06	0.00e+00	1691.00
IUUC-Sbi-114874	Sorghum bicolor	36.96	1.00e-143	503.00
IUUC-Sre-115130	Sporisorium reilianum	41.84	2.00e-77	284.00
IUUC-Ssc-115285	Sus scrofa	86.38	0.00e+00	1697.00
IUUC-Tgu-116529	Taeniopygia guttata	86.98	0.00e+00	1671.00
IUUC-Tru-118298	Takifugu rubripes	77.59	0.00e+00	1496.00
IUUC-Tsy-119117	Tarsius syrichta	78.17	0.00e+00	1027.00
IUUC-Tni-120093	Tetraodon nigroviridis	76.29	0.00e+00	1416.00
IUUC-Tca-121001	Theobroma cacao	36.05	1.00e-152	533.00
IUUC-Tre-121888	Trichoderma reesei	34.26	4.00e-62	233.00
IUUC-Tae-125295	Triticum aestivum	35.67	1.00e-148	520.00
IUUC-Tur-126149	Triticum urartu	37.46	1.00e-105	377.00
IUUC-Tbe-127672	Tupaia belangeri	78.96	0.00e+00	1118.00
IUUC-Vpa-130469	Vicugna pacos	86.57	0.00e+00	1635.00
IUUC-Vvi-131010	Vitis vinifera	38.00	3.00e-148	519.00
IUUC-Xtr-132729	Xenopus tropicalis	79.86	0.00e+00	1585.00
IUUC-Xma-133550	Xiphophorus maculatus	79.64	0.00e+00	1479.00
IUUC-Yli-134392	Yarrowia lipolytica	38.69	3.00e-64	240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence