iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008228

Ensembl Protein ID

CADACLAP00003810

UniProt Accession

A1CKR9; A1CKR9_ASPCL

Genbank Protein ID

EAW09743.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

DS027056

Gene Name

ACLA_039580

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00003890	CADACLAT00003890	CADACLAP00003810

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-49	167.1	47	636

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp....................kepkgellkslqklfeelw..kskkkavsp 70
           +Gl+N  N C++NSvLQ+L+ + +lr +l +  ++++l+  +                       ++g+++++l++++  l      kk ++ 
   Q: 47   VGLSNPANDCFINSVLQALAGLGDLRVYLIReLHRRELDGPEIynalpeasdmprgmrpdrlvGLQQGTITRALKEMLDRLNerPIYKKTITN 139
           6******************************6444444433336666667777777777777777777*************977677889999 PP
   S: 71   rellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde................. 129
           +++++al+ + ++  + +qqDaqEfl+++ ++l +e +                                                       
   Q: 140  QAFIQALEYAFRSRISRNQQDAQEFLQIVAERLCDEYHAglkarqraqglldveapA------------------Vsgsedsvqenpaaevev 214
           9*******99999889*****************999966554444443333332220..................134444566667777788 PP
   S: 130  ............aeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyyce 209
                         + k k+ ++     F+gql+sqi c+ c+ ++   + +f+ l+l+vp+k++t   +l++c++   k+e +++   + c+
   Q: 215  riddgsenglpaIIDTKLKELDNEPGFPFEGQLESQIECQFCHYQYrPNQTSFVNLTLQVPQKSST---TLSSCFDGLLKTEYIDD---FRCD 301
           888888888988677788888899999*******************9999**************99...***************97...**** PP
   S: 210  kck......................................................kkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           +c+                                                       k++  + ++++ +P+ + +hL+R  f++  +s++k
   Q: 302  RCRlqhalevkmvdlsksrstqergrlekeiqqiqhaiatdpeilpegvelppaelaPKRKIARHMRITVFPKLIAIHLSRSIFDR--SSSTK 392
           ***99**********9999999999999999999999999999999999999999998888*********************9988..5889* PP
   S: 249  inkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn........................................ 301
           +  kv+fp++L l   +++        + ++L+a+v+H+Gs++sGHY ++ +n                                        
   Q: 393  NAAKVSFPERLPLGGILNQ--------QWFKLLAIVCHKGSHNSGHYESFRRNhlyppfatpdvfssyaqsrvtsvnpstapsprltargtse 477
           **************88877........89**************************************************************** PP
   S: 302  ............................................................................................. 301
                                                                                                        
   Q: 478  telspisiststsspslsgtsisspvlsrspstkdssqqlnppsppsarpgtsssrrsfqslrsksssskqtlsppgsesqspasdsgnwsks 570
           ********************************************************************************************* PP
   S: 302  ................................ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
                                           ++++W++++D+k++e+k ++vl ++ ++ Y+lfY+
   Q: 571  aprpsfvserstlktsmeastlsssrlrrrkkTNDRWWRISDEKIKECKTSDVLGMQ-KEVYLLFYE 636
           *************99999999999999987655666*******************65.9*******8 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MQEKSTTIAA YAAGASLAAV ALFYVFGPNY TIDGDESNDS NRKKSIVGLS NPANDCFINS 60
VLQALAGLGD LRVYLIRELH RRELDGPEIY NALPEASDMP RGMRPDRLVG LQQGTITRAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGAGA AGTCGACCAC CATCGCCGCC TATGCGGCCG GCGCATCTCT CGCCGCCGTG 60
GCGCTCTTCT ACGTCTTCGG ACCGAACTAC ACCATTGACG GCGACGAGTC GAACGACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

act:ACLA_039580

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007955	Ashbya gossypii	26.68	5.00e-24	104.00
IUUC-Afl-008530	Aspergillus flavus	80.84	0.00e+00	771.00
IUUC-Afu-008943	Aspergillus fumigatus	83.20	0.00e+00	959.00
IUUC-Ang-009829	Aspergillus niger	70.35	0.00e+00	799.00
IUUC-Aor-009934	Aspergillus oryzae	81.15	0.00e+00	736.00
IUUC-Ate-010439	Aspergillus terreus	80.12	0.00e+00	773.00
IUUC-Bgr-012072	Blumeria graminis	76.92	2.00e-15	75.50
IUUC-Bci-013641	Botrytis cinerea	52.41	3.00e-129	454.00
IUUC-Cgl-026463	Colletotrichum gloeosporioides	52.64	9.00e-121	425.00
IUUC-Dse-031517	Dothistroma septosporum	49.90	6.00e-117	412.00
IUUC-Fox-037837	Fusarium oxysporum	45.16	1.00e-143	501.00
IUUC-Fso-038234	Fusarium solani	49.80	2.00e-126	444.00
IUUC-Ggr-039945	Gaeumannomyces graminis	59.90	1.00e-71	262.00
IUUC-Lma-053197	Leptosphaeria maculans	52.66	4.00e-106	376.00
IUUC-Mor-057061	Magnaporthe oryzae	53.04	1.00e-125	442.00
IUUC-Mpo-057549	Magnaporthe poae	58.21	3.00e-69	254.00
IUUC-Nfi-068557	Neosartorya fischeri	84.21	0.00e+00	956.00
IUUC-Ncr-068961	Neurospora crassa	49.49	2.00e-113	400.00
IUUC-Pno-094802	Phaeosphaeria nodorum	56.26	7.00e-135	472.00
IUUC-Pte-104416	Pyrenophora teres	53.65	7.00e-137	479.00
IUUC-Pyt-104503	Pyrenophora triticirepentis	50.86	5.00e-154	536.00
IUUC-Sce-106365	Saccharomyces cerevisiae	26.04	2.00e-21	95.10
IUUC-Tre-121937	Trichoderma reesei	45.18	6.00e-130	456.00
IUUC-Tvi-122428	Trichoderma virens	48.88	8.00e-117	412.00
IUUC-Tme-126993	Tuber melanosporum	48.58	5.00e-100	356.00
IUUC-Vda-129757	Verticillium dahliae	49.17	2.00e-117	414.00
IUUC-Yli-134426	Yarrowia lipolytica	31.80	4.00e-38	151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence