iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134556

Ensembl Protein ID

CAG84095

UniProt Accession

Q6CGP9; PFS2_YARLI

Genbank Protein ID

CAG84095.1

Protein Name

Polyadenylation factor subunit 2

Genbank Nucleotide ID

CR382127

Gene Name

PFS2; YALI0A17424g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_A17424g	CAG84095	CAG84095

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-31	104.7	228	259
UBD/Beta-Prp	9.40e-48	161.3	146	346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           H +s++ laf  sd+ +v+GsdDg +k+WD++
   Q: 228  HRESIRELAFapSDHKFVTGSDDGLLKIWDFH 259
           999********77799**************75 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvs 111
           +++++ +++pd++ l+tgs++g  ++w+  t ++ + ++ he++v+++k+s++g++l++g   +++k w +s ++  ++ k+h +s++ l+f ps++k+v+
   Q: 146  HPVYSATWTPDGRRLLTGSMSGEFTLWNGMTFNFESIMQAHESGVRSLKYSHSGEWLLSGDHEGNVKFWQPSLNCVNVIDKAHRESIRELAFAPSDHKFVT 246
           57788999******************************************************************999999********************* PP
   S: 112  GshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlq 210
           Gs+d  +++wd ++ +  e++l+gh   v +v +h++  l+vsGs+D+ ++lWd +++k + t+ g  ++ v +++f+++g  + l++g +d+t ++ dl+
   Q: 247  GSDDGLLKIWDFHESSNAESVLKGHGWDVKSVDWHSELGLIVSGSKDNLIKLWDPRSAKNVNTFHG-FKNTVMKTTFQPTGtkRLLAAGCRDRTCRILDLR 346
           ************************************99***************************9.**************9888999999*******998 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

Protein Sequence
(Fasta)

MSSDSGPLHR RTIPISVHIF SGFFYAPFYA PQLTQFIVTI TMYSTYQRPA GYQPRQQPQG 60
EEDRRPAHRR TVDHGSAFGK WHLDRLSGRT IQPANMRSEQ SYIVDLLPPS AYTNINGSLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCATCCG ATTCTGGGCC TCTCCATCGC CGTACCATTC CAATATCTGT TCACATTTTC 60
TCAGGATTTT TTTATGCACC GTTTTATGCA CCACAACTTA CTCAGTTCAT TGTCACGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0000790--C:nuclear chromatin
GO:0007059--P:chromosome segregation
GO:0006379--P:mRNA cleavage
GO:0006378--P:mRNA polyadenylation
GO:0098789--P:pre-mRNA cleavage required for polyadenylation

KEGG

yli:YALI0A17424g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	38.73	4.00e-77	280.00
IUUC-Aml-001363	Ailuropoda melanoleuca	37.19	2.00e-86	312.00
IUUC-Atr-003030	Amborella trichopoda	37.56	8.00e-78	282.00
IUUC-Apl-003409	Anas platyrhynchos	35.80	1.00e-84	306.00
IUUC-Aca-004694	Anolis carolinensis	37.27	4.00e-86	311.00
IUUC-Aly-006063	Arabidopsis lyrata	39.66	8.00e-79	285.00
IUUC-Ath-006583	Arabidopsis thaliana	41.75	7.00e-79	286.00
IUUC-Ago-007805	Ashbya gossypii	41.16	2.00e-99	353.00
IUUC-Acl-008075	Aspergillus clavatus	42.33	4.00e-91	327.00
IUUC-Afl-008582	Aspergillus flavus	41.44	2.00e-90	324.00
IUUC-Afu-008817	Aspergillus fumigatus	40.22	1.00e-77	281.00
IUUC-Ani-009391	Aspergillus nidulans	37.42	8.00e-82	295.00
IUUC-Ang-009750	Aspergillus niger	41.92	2.00e-75	273.00
IUUC-Aor-010085	Aspergillus oryzae	39.78	3.00e-92	330.00
IUUC-Ate-010397	Aspergillus terreus	40.32	3.00e-90	323.00
IUUC-Ame-010741	Astyanax mexicanus	41.00	3.00e-60	224.00
IUUC-Bgr-012169	Blumeria graminis	46.08	3.00e-95	340.00
IUUC-Bta-013265	Bos taurus	37.27	4.00e-86	311.00
IUUC-Bci-013762	Botrytis cinerea	45.32	8.00e-101	358.00
IUUC-Bdi-014849	Brachypodium distachyon	39.91	9.00e-82	296.00
IUUC-Bol-015325	Brassica oleracea	39.28	2.00e-79	288.00
IUUC-Bra-017064	Brassica rapa	40.15	3.00e-80	290.00
IUUC-Cel-018378	Caenorhabditis elegans	38.05	1.00e-77	282.00
IUUC-Cja-019547	Callithrix jacchus	37.27	3.00e-86	311.00
IUUC-Cfa-020031	Canis familiaris	37.27	3.00e-86	311.00
IUUC-Cpo-021554	Cavia porcellus	39.76	1.00e-83	303.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	33.33	1.00e-50	191.00
IUUC-Csa-023146	Chlorocebus sabaeus	37.27	2.00e-86	312.00
IUUC-Cho-024679	Choloepus hoffmanni	34.94	2.00e-76	278.00
IUUC-Cin-025415	Ciona intestinalis	39.69	1.00e-77	282.00
IUUC-Csv-026003	Ciona savignyi	41.18	1.00e-77	281.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	46.95	5.00e-101	359.00
IUUC-Cne-026983	Cryptococcus neoformans	38.75	7.00e-77	279.00
IUUC-Cme-027147	Cyanidioschyzon merolae	40.24	8.00e-83	298.00
IUUC-Dre-028545	Danio rerio	36.23	1.00e-84	306.00
IUUC-Dno-029677	Dasypus novemcinctus	37.27	2.00e-86	312.00
IUUC-Dse-031371	Dothistroma septosporum	41.40	6.00e-88	316.00
IUUC-Dme-031663	Drosophila melanogaster	40.64	3.00e-88	317.00
IUUC-Ete-032511	Echinops telfairi	32.30	2.00e-64	239.00
IUUC-Eca-034152	Equus caballus	37.27	3.00e-86	311.00
IUUC-Eeu-034560	Erinaceus europaeus	30.20	2.00e-25	109.00
IUUC-Fca-035820	Felis catus	37.06	4.00e-86	311.00
IUUC-Fox-037958	Fusarium oxysporum	44.63	9.00e-103	365.00
IUUC-Fso-038162	Fusarium solani	43.97	2.00e-102	364.00
IUUC-Gmo-039708	Gadus morhua	35.46	2.00e-85	308.00
IUUC-Ggr-040031	Gaeumannomyces graminis	41.53	6.00e-92	329.00
IUUC-Gga-040963	Gallus gallus	35.93	3.00e-86	311.00
IUUC-Gac-041541	Gasterosteus aculeatus	35.54	7.00e-84	303.00
IUUC-Gma-044352	Glycine max	39.37	6.00e-82	296.00
IUUC-Ggo-045564	Gorilla gorilla	37.27	3.00e-86	311.00
IUUC-Hsa-045833	Homo sapiens	37.27	2.00e-86	311.00
IUUC-Hvu-047848	Hordeum vulgare	39.40	1.00e-58	218.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	37.27	3.00e-86	311.00
IUUC-Kpa-049308	Komagataella pastoris	47.25	7.00e-114	401.00
IUUC-Lch-050525	Latimeria chalumnae	35.07	4.00e-84	304.00
IUUC-Lpe-051364	Leersia perrieri	36.62	3.00e-69	254.00
IUUC-Loc-052696	Lepisosteus oculatus	35.36	1.00e-84	306.00
IUUC-Lma-052951	Leptosphaeria maculans	45.57	1.00e-100	358.00
IUUC-Laf-053653	Loxodonta africana	37.27	8.00e-86	310.00
IUUC-Mcc-055797	Macaca mulatta	37.27	3.00e-86	311.00
IUUC-Meu-056331	Macropus eugenii	37.15	3.00e-70	258.00
IUUC-Mor-057168	Magnaporthe oryzae	42.47	7.00e-95	339.00
IUUC-Mpo-057510	Magnaporthe poae	48.57	1.00e-66	244.00
IUUC-Mtr-058032	Medicago truncatula	40.19	2.00e-83	301.00
IUUC-Mla-058852	Melampsora laricipopulina	38.22	2.00e-89	321.00
IUUC-Mga-059311	Meleagris gallopavo	37.27	4.00e-86	311.00
IUUC-Mvi-060544	Microbotryum violaceum	41.48	2.00e-88	317.00
IUUC-Mmr-061143	Microcebus murinus	37.27	3.00e-86	311.00
IUUC-Mdo-061977	Monodelphis domestica	37.27	4.00e-86	311.00
IUUC-Mmu-063922	Mus musculus	37.27	3.00e-86	311.00
IUUC-Mac-064961	Musa acuminata	39.86	2.00e-83	301.00
IUUC-Mpu-066079	Mustela putorius furo	41.14	6.00e-81	294.00
IUUC-Mlu-067247	Myotis lucifugus	37.27	1.00e-86	313.00
IUUC-Nfi-068255	Neosartorya fischeri	41.96	1.00e-86	311.00
IUUC-Ncr-068909	Neurospora crassa	46.98	4.00e-102	363.00
IUUC-Nle-068994	Nomascus leucogenys	37.27	2.00e-86	312.00
IUUC-Opr-071079	Ochotona princeps	37.06	2.00e-85	309.00
IUUC-Ont-071971	Oreochromis niloticus	35.08	1.00e-83	303.00
IUUC-Oan-073135	Ornithorhynchus anatinus	40.10	2.00e-82	299.00
IUUC-Ocu-073982	Oryctolagus cuniculus	37.27	3.00e-86	311.00
IUUC-Oba-075297	Oryza barthii	36.62	1.00e-71	262.00
IUUC-Obr-076641	Oryza brachyantha	40.38	1.00e-83	301.00
IUUC-Ogl-077539	Oryza glaberrima	39.74	3.00e-60	223.00
IUUC-Ogu-078807	Oryza glumaepatula	36.62	1.00e-71	262.00
IUUC-Oin-079229	Oryza indica	40.38	7.00e-84	303.00
IUUC-Olo-080371	Oryza longistaminata	36.62	1.00e-71	262.00
IUUC-Ome-081149	Oryza meridionalis	36.62	4.00e-71	260.00
IUUC-Oni-082970	Oryza nivara	36.62	1.00e-71	262.00
IUUC-Opu-083415	Oryza punctata	35.60	2.00e-69	254.00
IUUC-Oru-085236	Oryza rufipogon	36.62	1.00e-71	261.00
IUUC-Ola-087421	Oryzias latipes	35.08	7.00e-86	309.00
IUUC-Olu-087821	Ostreococcus lucimarinus	37.44	2.00e-74	270.00
IUUC-Oga-088132	Otolemur garnettii	37.27	3.00e-86	311.00
IUUC-Oar-089513	Ovis aries	37.27	4.00e-86	311.00
IUUC-Ptr-090717	Pan troglodytes	37.27	3.00e-86	311.00
IUUC-Pan-092108	Papio anubis	37.27	3.00e-86	311.00
IUUC-Psi-093892	Pelodiscus sinensis	37.27	4.00e-86	311.00
IUUC-Pma-094561	Petromyzon marinus	39.06	8.00e-84	303.00
IUUC-Pno-094943	Phaeosphaeria nodorum	43.68	2.00e-102	363.00
IUUC-Ppa-095359	Physcomitrella patens	40.24	4.00e-85	306.00
IUUC-Pfo-096516	Poecilia formosa	36.78	1.00e-83	302.00
IUUC-Pab-097759	Pongo abelii	37.27	3.00e-86	311.00
IUUC-Pop-099553	Populus trichocarpa	40.00	2.00e-83	301.00
IUUC-Ppe-101957	Prunus persica	40.38	1.00e-83	301.00
IUUC-Pva-102918	Pteropus vampyrus	37.27	3.00e-86	311.00
IUUC-Pgr-103594	Puccinia graminis	37.73	6.00e-88	316.00
IUUC-Ptt-103879	Puccinia triticina	43.60	1.00e-77	281.00
IUUC-Pte-104419	Pyrenophora teres	44.06	4.00e-102	363.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	45.61	1.00e-100	358.00
IUUC-Rno-105838	Rattus norvegicus	37.27	4.00e-86	311.00
IUUC-Sce-106331	Saccharomyces cerevisiae	40.77	1.00e-91	328.00
IUUC-Sha-107435	Sarcophilus harrisii	37.11	6.00e-86	310.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	43.15	4.00e-101	359.00
IUUC-Spo-108163	Schizosaccharomyces pombe	42.36	1.00e-96	344.00
IUUC-Smo-108972	Selaginella moellendorffii	41.37	2.00e-88	317.00
IUUC-Sit-109729	Setaria italica	40.14	7.00e-83	299.00
IUUC-Sly-111679	Solanum lycopersicum	41.29	3.00e-83	300.00
IUUC-Sar-113157	Sorex araneus	37.19	2.00e-86	311.00
IUUC-Sbi-114853	Sorghum bicolor	39.44	2.00e-80	291.00
IUUC-Sre-115085	Sporisorium reilianum	35.39	9.00e-83	299.00
IUUC-Ssc-116286	Sus scrofa	37.19	2.00e-85	308.00
IUUC-Tgu-117219	Taeniopygia guttata	35.93	7.00e-86	310.00
IUUC-Tru-117550	Takifugu rubripes	35.43	7.00e-86	309.00
IUUC-Tsy-119294	Tarsius syrichta	37.27	1.00e-86	312.00
IUUC-Tni-120561	Tetraodon nigroviridis	35.93	3.00e-86	311.00
IUUC-Tca-121347	Theobroma cacao	38.26	1.00e-82	298.00
IUUC-Tre-122018	Trichoderma reesei	46.33	2.00e-102	364.00
IUUC-Tvi-122413	Trichoderma virens	46.33	6.00e-103	365.00
IUUC-Tae-123191	Triticum aestivum	39.91	3.00e-82	297.00
IUUC-Tme-127077	Tuber melanosporum	47.22	1.00e-114	405.00
IUUC-Tbe-127744	Tupaia belangeri	33.90	1.00e-41	164.00
IUUC-Ttr-128777	Tursiops truncatus	33.98	7.00e-63	234.00
IUUC-Uma-129568	Ustilago maydis	36.06	4.00e-79	286.00
IUUC-Vda-129834	Verticillium dahliae	44.37	8.00e-103	365.00
IUUC-Vvi-131360	Vitis vinifera	39.91	8.00e-83	299.00
IUUC-Xtr-132630	Xenopus tropicalis	37.68	5.00e-85	307.00
IUUC-Xma-133665	Xiphophorus maculatus	36.65	5.00e-85	307.00
IUUC-Zma-135787	Zea mays	39.91	5.00e-82	296.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence