iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssl-108553

Ensembl Protein ID

EDN96618

UniProt Accession

A7E8B6; SLA1_SCLS1

Genbank Protein ID

EDN96618.1

Protein Name

Actin cytoskeleton-regulatory complex protein sla1

Genbank Nucleotide ID

CH476622

Gene Name

sla1; SS1G_01544

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SS1G_01544	EDN96618	EDN96618

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-40	134.3	7	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk.....elegkrGlfPenFvekl 62
             + ydy ++ ++eLt+k+Gd+++v+ +++++ +W+k++k     +  +  Gl+P+n+++++
   Q: 7    YSAVYDYVPAGEGELTIKEGDILYVL-EKSTEDDWWKAKKkasaeDEDEPVGLIPNNYIQEA 67
           6799**********************.999********9999998778889********986 PP

Organism

Sclerotinia sclerotiorum

Functional Description
(View)

Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).

Protein Sequence
(Fasta)

MGFLGVYSAV YDYVPAGEGE LTIKEGDILY VLEKSTEDDW WKAKKKASAE DEDEPVGLIP 60
NNYIQEAAPS GKARALYDYT RQTDEELSFT EDAQLEVFDT SDPDWILVGF EGEYGFVPAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTTTCT TGGGTGTTTA TTCTGCAGTA TACGATTACG TGCCGGCAGG TGAGGGAGAG 60
CTCACTATTA AAGAAGGGGA TATCCTCTAC GTGCTAGAGA AGAGCACGGA AGACGATTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0254--Endocytosis
KW-0967--Endosome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR013182--DUF1720
IPR013761--SAM/pointed
IPR001452--SH3_domain
IPR007131--SHD1
IPR029922--Sla1

PROSITE

PS50002--SH3

Pfam

PF08226--DUF1720
PF00018--SH3_1
PF14604--SH3_9
PF03983--SHD1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0007015--P:actin filament organization
GO:0006897--P:endocytosis

KEGG

ssl:SS1G_01544

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007979	Ashbya gossypii	33.97	1.00e-44	173.00
IUUC-Acl-008300	Aspergillus clavatus	55.84	1.00e-165	575.00
IUUC-Afl-008694	Aspergillus flavus	51.50	2.00e-145	508.00
IUUC-Afu-008881	Aspergillus fumigatus	57.44	1.00e-170	592.00
IUUC-Ani-009274	Aspergillus nidulans	54.79	4.00e-145	506.00
IUUC-Ang-009534	Aspergillus niger	55.59	1.00e-170	591.00
IUUC-Aor-010097	Aspergillus oryzae	58.70	6.00e-161	559.00
IUUC-Ate-010495	Aspergillus terreus	59.57	1.00e-150	525.00
IUUC-Bgr-012294	Blumeria graminis	49.01	0.00e+00	924.00
IUUC-Bci-013990	Botrytis cinerea	82.45	0.00e+00	1428.00
IUUC-Cel-018144	Caenorhabditis elegans	28.26	2.00e-12	64.70
IUUC-Cgl-026697	Colletotrichum gloeosporioides	61.84	0.00e+00	672.00
IUUC-Cne-026842	Cryptococcus neoformans	39.15	2.00e-45	175.00
IUUC-Dse-031496	Dothistroma septosporum	51.34	0.00e+00	690.00
IUUC-Dme-031846	Drosophila melanogaster	32.12	4.00e-12	63.90
IUUC-Fox-037778	Fusarium oxysporum	28.30	4.00e-12	64.70
IUUC-Fso-038358	Fusarium solani	60.22	0.00e+00	670.00
IUUC-Ggr-040032	Gaeumannomyces graminis	56.59	3.00e-161	560.00
IUUC-Kpa-049118	Komagataella pastoris	34.98	1.00e-76	279.00
IUUC-Loc-051874	Lepisosteus oculatus	28.03	7.00e-15	73.90
IUUC-Lma-053236	Leptosphaeria maculans	57.54	6.00e-147	512.00
IUUC-Mor-056954	Magnaporthe oryzae	50.20	0.00e+00	753.00
IUUC-Mpo-057576	Magnaporthe poae	58.08	4.00e-172	597.00
IUUC-Mla-059035	Melampsora laricipopulina	35.43	5.00e-39	154.00
IUUC-Mvi-060454	Microbotryum violaceum	32.77	4.00e-34	138.00
IUUC-Nfi-068406	Neosartorya fischeri	57.97	4.00e-172	596.00
IUUC-Ncr-068902	Neurospora crassa	53.35	0.00e+00	777.00
IUUC-Oba-075752	Oryza barthii	33.33	4.00e-04	39.70
IUUC-Pno-094774	Phaeosphaeria nodorum	47.80	0.00e+00	637.00
IUUC-Pgr-103396	Puccinia graminis	35.31	7.00e-41	160.00
IUUC-Ptt-103751	Puccinia triticina	35.71	1.00e-43	169.00
IUUC-Pte-104349	Pyrenophora teres	51.63	4.00e-138	483.00
IUUC-Pyt-104695	Pyrenophora triticirepentis	49.83	0.00e+00	632.00
IUUC-Sce-106372	Saccharomyces cerevisiae	38.82	3.00e-32	132.00
IUUC-Sja-107962	Schizosaccharomyces japonicus	28.44	8.00e-51	194.00
IUUC-Spo-108375	Schizosaccharomyces pombe	31.23	3.00e-34	139.00
IUUC-Sre-115072	Sporisorium reilianum	44.76	4.00e-27	115.00
IUUC-Tre-121912	Trichoderma reesei	57.95	4.00e-173	599.00
IUUC-Tvi-122336	Trichoderma virens	57.89	6.00e-172	596.00
IUUC-Tme-127017	Tuber melanosporum	40.50	2.00e-90	324.00
IUUC-Uma-129502	Ustilago maydis	43.05	5.00e-27	114.00
IUUC-Vda-129879	Verticillium dahliae	56.95	0.00e+00	808.00
IUUC-Yli-134528	Yarrowia lipolytica	51.18	1.00e-51	196.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence