iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073040

Ensembl Protein ID

ENSOANP00000016941.1

UniProt Accession

F6T986; F6T986_ORNAN

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000010683.2	ENSOANT00000016944.1	ENSOANP00000016941.1
ENSOANG00000010683.2	ENSOANT00000016946.1	ENSOANP00000016943.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-12	47.6	60	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +lyd++a nd +L+++kG++++++    q ++W+ +++  +g++G +P n+v++++
   Q: 60   VALYDFDALNDRDLQMRKGEKLQIL---IQTGDWWLAKSLVTGREGYIPGNYVARVD 113
           58***********************...9*************************997 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MGAVSSKKQA KVKEKNLWSA PKADQVPPRN QTPPPLPPSV SDAPPSRPPY QGESEEIFAV 60
ALYDFDALND RDLQMRKGEK LQILIQTGDW WLAKSLVTGR EGYIPGNYVA RVDTLEVEKW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGCGG TGAGCAGTAA GAAGCAGGCC AAGGTCAAAG AGAAGAACCT CTGGAGTGCC 60
CCAAAGGCGG ACCAGGTCCC CCCTCGGAAT CAGACACCCC CTCCGCTGCC ACCTTCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0050853--P:B cell receptor signaling pathway
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0032024--P:positive regulation of insulin secretion
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bgr-012089	Blumeria graminis	42.86	1.00e-08	53.90
IUUC-Ete-032602	Echinops telfairi	63.97	5.00e-87	313.00
IUUC-Mla-059035	Melampsora laricipopulina	35.48	4.00e-09	57.00
IUUC-Oba-075752	Oryza barthii	36.96	1.40e-02	36.20
IUUC-Tre-122063	Trichoderma reesei	38.75	8.00e-09	53.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence