iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047649

Ensembl Protein ID

MLOC_51259.2

UniProt Accession

M0WGK2; M0WGK2_HORVV

Protein Name

Katanin p80 WD40 repeat-containing subunit B1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_51259	MLOC_51259.1	MLOC_51259.1
MLOC_51259	MLOC_51259.2	MLOC_51259.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-36	123.1	143	181
UBD/Beta-Prp	2.90e-57	195.2	16	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt +v++++f +d + +vsG+ D  +k+WDl+ g+ll+
   Q: 143  GHTRGVNAIRFtPDgRWVVSGGEDSAVKIWDLTAGKLLH 181
           8***********99999******************9987 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           +h s ++c+k+  + +++l+tg++d+++ +w + +++ ++sl gh+++v +v f++++ + + g+  +t+k+wdl+ +k+v+tl+gh ++ +s++f+
   Q: 16   AHASNVNCLKIgRKTSRVLVTGGEDHKVNLWAIGKPNSISSLPGHTSAVESVAFDSTEVFVAAGAASGTVKLWDLEESKIVRTLTGHRSNCMSVDFH 112
           68889999***999********************************************9999*********************************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsl 200
           p g++++sGs d  +++wd++ + c++ t +gh++ vn +++ pdg+ +vsG+ D++v++Wdl  gkll+++++ h++++++++f++  + l++gs 
   Q: 113  PFGEFFASGSLDTNLKIWDIRRKGCIH-TYKGHTRGVNAIRFTPDGRWVVSGGEDSAVKIWDLTAGKLLHEFKS-HEGQIQCIDFHPHEFLLATGSA 207
           ***************************.*********************************************9.********************** PP
   S: 201  dgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav 272
           d+tvk+wdl+t e + +     + v+s+ f p++  l++g  ++s++++  +   +  t+    s+++   v
   Q: 208  DKTVKFWDLETFELIGSTGPEMTGVRSMTFNPDGRSLLCG-LHESLKVFSWEPIRCHDTVDVGWSRLSDLNV 278
           *******************************999999999.5888888766666666666666655555555 PP

Organism

Hordeum vulgare

Functional Description
(View)

May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.

Protein Sequence
(Fasta)

MTTNTKRAYK LQEFVAHASN VNCLKIGRKT SRVLVTGGED HKVNLWAIGK PNSISSLPGH 60
TSAVESVAFD STEVFVAAGA ASGTVKLWDL EESKIVRTLT GHRSNCMSVD FHPFGEFFAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAGATCCG GGGGCGGCGG CGCGATCTGG GCGTGGCATG AGATTGGGGC TGGCGGCGCG 60
GCGGTGAGGC GAGGCGAGGC GCGGCGCCCG GCGGCATGAC GACCAACACC AAGCGCGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0051013--P:microtubule severing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	83.11	0.00e+00	1566.00
IUUC-Aml-002187	Ailuropoda melanoleuca	52.60	5.00e-101	360.00
IUUC-Apl-003305	Anas platyrhynchos	50.85	5.00e-100	357.00
IUUC-Aca-004635	Anolis carolinensis	49.35	9.00e-92	330.00
IUUC-Aly-005711	Arabidopsis lyrata	64.34	0.00e+00	627.00
IUUC-Ath-007606	Arabidopsis thaliana	63.10	0.00e+00	626.00
IUUC-Acl-008307	Aspergillus clavatus	31.66	2.00e-29	122.00
IUUC-Bgr-012225	Blumeria graminis	30.00	3.00e-29	121.00
IUUC-Bta-012527	Bos taurus	53.25	3.00e-104	371.00
IUUC-Bdi-014652	Brachypodium distachyon	86.90	0.00e+00	1612.00
IUUC-Bol-016374	Brassica oleracea	59.09	4.00e-178	617.00
IUUC-Bra-017390	Brassica rapa	76.00	1.00e-176	612.00
IUUC-Cja-019706	Callithrix jacchus	53.25	8.00e-104	369.00
IUUC-Cfa-020139	Canis familiaris	45.88	5.00e-97	347.00
IUUC-Cpo-021710	Cavia porcellus	52.92	4.00e-104	370.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	44.95	8.00e-83	300.00
IUUC-Csa-023546	Chlorocebus sabaeus	53.29	4.00e-100	357.00
IUUC-Cin-025156	Ciona intestinalis	46.51	1.00e-87	316.00
IUUC-Csv-025962	Ciona savignyi	48.65	2.00e-87	313.00
IUUC-Dre-028215	Danio rerio	50.47	7.00e-103	366.00
IUUC-Dno-029314	Dasypus novemcinctus	53.57	8.00e-104	369.00
IUUC-Dor-030482	Dipodomys ordii	53.25	1.00e-104	372.00
IUUC-Dme-032188	Drosophila melanogaster	36.58	5.00e-59	221.00
IUUC-Eca-034143	Equus caballus	53.18	5.00e-101	360.00
IUUC-Fca-035924	Felis catus	53.57	2.00e-104	371.00
IUUC-Fal-037387	Ficedula albicollis	51.49	6.00e-103	366.00
IUUC-Gmo-038692	Gadus morhua	48.80	1.00e-102	365.00
IUUC-Gga-040597	Gallus gallus	51.84	1.00e-102	365.00
IUUC-Gac-042004	Gasterosteus aculeatus	51.32	2.00e-98	351.00
IUUC-Ggo-044761	Gorilla gorilla	53.25	8.00e-104	369.00
IUUC-Hsa-045698	Homo sapiens	51.06	3.00e-104	370.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	53.25	2.00e-104	371.00
IUUC-Lch-049674	Latimeria chalumnae	44.80	8.00e-106	376.00
IUUC-Lpe-051554	Leersia perrieri	78.53	0.00e+00	1481.00
IUUC-Loc-052623	Lepisosteus oculatus	51.94	2.00e-100	358.00
IUUC-Laf-054587	Loxodonta africana	53.25	4.00e-104	370.00
IUUC-Mcc-055851	Macaca mulatta	53.25	8.00e-104	369.00
IUUC-Meu-056704	Macropus eugenii	53.85	2.00e-104	372.00
IUUC-Mpo-057381	Magnaporthe poae	32.81	7.00e-27	114.00
IUUC-Mtr-058053	Medicago truncatula	73.39	0.00e+00	665.00
IUUC-Mga-059608	Meleagris gallopavo	50.00	2.00e-99	355.00
IUUC-Mmr-061154	Microcebus murinus	53.25	5.00e-104	370.00
IUUC-Mdo-062365	Monodelphis domestica	53.85	8.00e-104	369.00
IUUC-Mmu-063754	Mus musculus	53.51	4.00e-104	370.00
IUUC-Mac-064439	Musa acuminata	48.28	0.00e+00	713.00
IUUC-Mpu-066245	Mustela putorius furo	53.90	1.00e-104	372.00
IUUC-Mlu-067692	Myotis lucifugus	53.36	4.00e-103	367.00
IUUC-Nle-070051	Nomascus leucogenys	52.92	8.00e-103	366.00
IUUC-Opr-070855	Ochotona princeps	53.51	3.00e-104	371.00
IUUC-Ont-071883	Oreochromis niloticus	50.50	2.00e-98	352.00
IUUC-Oan-073293	Ornithorhynchus anatinus	54.09	4.00e-101	360.00
IUUC-Ocu-074644	Oryctolagus cuniculus	53.25	2.00e-104	371.00
IUUC-Oba-075448	Oryza barthii	62.92	0.00e+00	1046.00
IUUC-Obr-076385	Oryza brachyantha	79.94	0.00e+00	1460.00
IUUC-Ogl-077427	Oryza glaberrima	79.75	0.00e+00	1476.00
IUUC-Ogu-078428	Oryza glumaepatula	56.26	0.00e+00	871.00
IUUC-Oin-079811	Oryza indica	78.64	0.00e+00	1464.00
IUUC-Olo-080245	Oryza longistaminata	75.81	0.00e+00	1385.00
IUUC-Ome-081239	Oryza meridionalis	76.82	0.00e+00	1365.00
IUUC-Oni-082640	Oryza nivara	62.92	0.00e+00	1046.00
IUUC-Opu-083748	Oryza punctata	74.60	0.00e+00	1353.00
IUUC-Oru-084609	Oryza rufipogon	62.92	0.00e+00	1046.00
IUUC-Osa-085988	Oryza sativa	74.76	0.00e+00	1350.00
IUUC-Ola-087483	Oryzias latipes	49.33	2.00e-94	338.00
IUUC-Oga-087964	Otolemur garnettii	53.51	4.00e-104	370.00
IUUC-Oar-089483	Ovis aries	52.92	4.00e-102	364.00
IUUC-Ptr-091387	Pan troglodytes	51.06	3.00e-104	371.00
IUUC-Pan-092623	Papio anubis	53.25	8.00e-104	369.00
IUUC-Psi-093830	Pelodiscus sinensis	50.97	2.00e-98	352.00
IUUC-Ppa-095379	Physcomitrella patens	78.64	5.00e-154	536.00
IUUC-Pfo-096755	Poecilia formosa	50.66	2.00e-98	352.00
IUUC-Pab-097564	Pongo abelii	53.25	2.00e-103	368.00
IUUC-Pop-099149	Populus trichocarpa	64.43	0.00e+00	664.00
IUUC-Pca-100357	Procavia capensis	57.35	2.00e-76	278.00
IUUC-Ppe-101237	Prunus persica	74.95	0.00e+00	689.00
IUUC-Pva-102397	Pteropus vampyrus	49.03	2.00e-91	328.00
IUUC-Rno-105349	Rattus norvegicus	53.51	3.00e-104	371.00
IUUC-Smo-109379	Selaginella moellendorffii	78.33	1.00e-155	542.00
IUUC-Sit-110360	Setaria italica	80.56	0.00e+00	1466.00
IUUC-Sly-111307	Solanum lycopersicum	70.26	0.00e+00	654.00
IUUC-Stu-112462	Solanum tuberosum	68.43	0.00e+00	626.00
IUUC-Sar-112953	Sorex araneus	45.61	2.00e-58	219.00
IUUC-Ssc-115949	Sus scrofa	47.37	6.00e-49	187.00
IUUC-Tgu-117461	Taeniopygia guttata	51.49	2.00e-103	369.00
IUUC-Tru-117865	Takifugu rubripes	48.67	7.00e-92	330.00
IUUC-Tsy-119036	Tarsius syrichta	59.50	3.00e-40	158.00
IUUC-Tni-120903	Tetraodon nigroviridis	48.84	7.00e-92	330.00
IUUC-Tca-121185	Theobroma cacao	53.08	0.00e+00	904.00
IUUC-Tae-125307	Triticum aestivum	96.65	0.00e+00	1819.00
IUUC-Tur-126411	Triticum urartu	83.52	0.00e+00	1529.00
IUUC-Ttr-128172	Tursiops truncatus	53.25	2.00e-104	372.00
IUUC-Vvi-131489	Vitis vinifera	72.98	0.00e+00	686.00
IUUC-Xtr-132915	Xenopus tropicalis	52.65	6.00e-101	360.00
IUUC-Xma-134133	Xiphophorus maculatus	50.00	4.00e-96	344.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence