iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108104

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2 15; E2 ubiquitin-conjugating enzyme 15; Ubiquitin carrier protein 15; Ubiquitin-protein ligase 15

Genbank Nucleotide ID

CU329671

Gene Name

ubc15; SPBC1105.09

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC1105.09	SPBC1105.09.1	SPBC1105.09.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.20e-50	166.7	10	157

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...... 87
           l+k+lke++k+pp+g+s+++vd++ ++ewev+i+Gpedt Yegg+F+++++fp+dYP+ PPk+kf+t+i+hPnv++nG+vC+sil+      
   Q: 10   LRKQLKEIQKNPPQGFSVGLVDDKSIFEWEVMIIGPEDTLYEGGFFHATLSFPQDYPLMPPKMKFTTEIWHPNVHPNGEVCISILHppgddk 101
           6899*********************************************************************************8888999 PP
   S: 88   .....eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
                  e+W p++s e++l+s++s+l++pn esp+n +aa+++++n++e+kk+vr
   Q: 102  ygyedAGERWLPVHSPETILISVISMLSSPNDESPANIDAAKEFRENPQEFKKRVR 157
           9999999***********************************************98 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Catalyzes the covalent attachment of ubiquitin to other proteins. Has a role in the formation of chromatin structures that influence the localization of transcriptional silencing factors.

Protein Sequence
(Fasta)

MPSSASEQLL RKQLKEIQKN PPQGFSVGLV DDKSIFEWEV MIIGPEDTLY EGGFFHATLS 60
FPQDYPLMPP KMKFTTEIWH PNVHPNGEVC ISILHPPGDD KYGYEDAGER WLPVHSPETI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGAAATT TGAAAATTGT AATCTTAACC AAAATGTTTA CTTAGAGTAA ATTAAATTTA 60
TGTTTTCTAC GTTAAAAGCT TTATTATATG TTACATAAAT AATACAAAAA AGGAATATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0061186--P:negative regulation of chromatin silencing at silent mating-type cassette
GO:0031939--P:negative regulation of chromatin silencing at telomere
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

spo:SPBC1105.09

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	51.11	1.00e-41	160.00
IUUC-Aml-001379	Ailuropoda melanoleuca	67.83	2.00e-57	212.00
IUUC-Atr-003150	Amborella trichopoda	68.61	8.00e-44	167.00
IUUC-Apl-003579	Anas platyrhynchos	68.57	2.00e-57	212.00
IUUC-Aca-005146	Anolis carolinensis	70.68	3.00e-56	208.00
IUUC-Aly-005673	Arabidopsis lyrata	68.24	4.00e-49	185.00
IUUC-Ath-007644	Arabidopsis thaliana	68.24	4.00e-49	185.00
IUUC-Acl-008329	Aspergillus clavatus	62.58	1.00e-52	196.00
IUUC-Afl-008660	Aspergillus flavus	62.58	1.00e-53	199.00
IUUC-Afu-008841	Aspergillus fumigatus	68.46	1.00e-49	186.00
IUUC-Ani-009165	Aspergillus nidulans	60.65	3.00e-50	188.00
IUUC-Ang-009536	Aspergillus niger	63.23	1.00e-53	199.00
IUUC-Aor-009951	Aspergillus oryzae	61.76	7.00e-54	201.00
IUUC-Ate-010276	Aspergillus terreus	63.23	1.00e-53	199.00
IUUC-Ame-010634	Astyanax mexicanus	70.54	3.00e-56	212.00
IUUC-Bta-013324	Bos taurus	70.99	2.00e-55	206.00
IUUC-Bdi-014838	Brachypodium distachyon	65.66	1.00e-52	196.00
IUUC-Bol-016503	Brassica oleracea	67.11	6.00e-49	184.00
IUUC-Bra-017324	Brassica rapa	63.40	1.00e-47	179.00
IUUC-Cel-018162	Caenorhabditis elegans	67.35	6.00e-57	210.00
IUUC-Cja-018734	Callithrix jacchus	70.68	2.00e-56	209.00
IUUC-Cfa-020846	Canis familiaris	70.68	2.00e-56	209.00
IUUC-Cpo-022207	Cavia porcellus	69.63	3.00e-56	208.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	67.07	2.00e-55	205.00
IUUC-Csa-024193	Chlorocebus sabaeus	70.99	2.00e-55	206.00
IUUC-Cin-025131	Ciona intestinalis	62.84	2.00e-56	209.00
IUUC-Csv-026074	Ciona savignyi	65.79	2.00e-56	209.00
IUUC-Cne-026796	Cryptococcus neoformans	60.27	3.00e-44	169.00
IUUC-Cme-027321	Cyanidioschyzon merolae	60.98	3.00e-47	179.00
IUUC-Dre-028286	Danio rerio	66.06	4.00e-60	221.00
IUUC-Dno-029479	Dasypus novemcinctus	70.99	2.00e-55	206.00
IUUC-Dor-030686	Dipodomys ordii	51.39	1.00e-42	163.00
IUUC-Dse-031230	Dothistroma septosporum	62.33	2.00e-48	182.00
IUUC-Dme-032132	Drosophila melanogaster	72.73	6.00e-57	211.00
IUUC-Ete-032885	Echinops telfairi	70.99	2.00e-55	206.00
IUUC-Eca-034057	Equus caballus	70.68	3.00e-56	208.00
IUUC-Eeu-035128	Erinaceus europaeus	50.00	8.00e-34	134.00
IUUC-Fca-035835	Felis catus	70.68	3.00e-56	208.00
IUUC-Fal-036778	Ficedula albicollis	70.99	2.00e-55	206.00
IUUC-Gmo-039504	Gadus morhua	67.88	3.00e-61	224.00
IUUC-Gga-040950	Gallus gallus	70.99	2.00e-55	206.00
IUUC-Gac-042210	Gasterosteus aculeatus	68.24	4.00e-62	228.00
IUUC-Gma-044131	Glycine max	66.45	6.00e-43	164.00
IUUC-Ggo-044826	Gorilla gorilla	70.99	2.00e-55	206.00
IUUC-Hsa-046638	Homo sapiens	70.99	2.00e-55	206.00
IUUC-Hvu-047065	Hordeum vulgare	64.71	1.00e-48	184.00
IUUC-Lch-049915	Latimeria chalumnae	66.67	1.00e-60	223.00
IUUC-Lpe-051124	Leersia perrieri	66.22	6.00e-48	181.00
IUUC-Loc-052018	Lepisosteus oculatus	67.27	1.00e-60	223.00
IUUC-Lma-053320	Leptosphaeria maculans	62.50	1.00e-50	190.00
IUUC-Laf-053491	Loxodonta africana	70.99	2.00e-55	206.00
IUUC-Mcc-055624	Macaca mulatta	69.40	3.00e-56	208.00
IUUC-Meu-056870	Macropus eugenii	68.94	3.00e-50	188.00
IUUC-Mtr-058406	Medicago truncatula	65.79	1.00e-48	183.00
IUUC-Mla-059165	Melampsora laricipopulina	64.07	2.00e-59	219.00
IUUC-Mga-060005	Meleagris gallopavo	70.68	3.00e-56	208.00
IUUC-Mvi-060318	Microbotryum violaceum	62.42	1.00e-48	183.00
IUUC-Mmr-061442	Microcebus murinus	70.99	2.00e-55	206.00
IUUC-Mdo-062364	Monodelphis domestica	66.89	1.00e-58	216.00
IUUC-Mmu-064163	Mus musculus	70.99	2.00e-55	206.00
IUUC-Mac-065294	Musa acuminata	65.36	1.00e-49	187.00
IUUC-Mpu-066561	Mustela putorius furo	68.57	1.00e-57	213.00
IUUC-Mlu-067331	Myotis lucifugus	70.99	2.00e-55	206.00
IUUC-Nfi-068431	Neosartorya fischeri	68.46	1.00e-49	186.00
IUUC-Ncr-068668	Neurospora crassa	56.76	1.00e-44	170.00
IUUC-Opr-070958	Ochotona princeps	70.45	1.00e-55	206.00
IUUC-Ont-072627	Oreochromis niloticus	70.75	3.00e-62	228.00
IUUC-Ocu-074321	Oryctolagus cuniculus	69.85	2.00e-56	209.00
IUUC-Oba-075915	Oryza barthii	67.57	4.00e-54	201.00
IUUC-Obr-076863	Oryza brachyantha	67.57	7.00e-48	181.00
IUUC-Ogl-076981	Oryza glaberrima	67.57	4.00e-54	201.00
IUUC-Ogu-078183	Oryza glumaepatula	67.57	4.00e-54	201.00
IUUC-Oin-079755	Oryza indica	67.57	4.00e-54	201.00
IUUC-Olo-080576	Oryza longistaminata	67.57	4.00e-54	201.00
IUUC-Ome-081190	Oryza meridionalis	63.69	1.00e-51	193.00
IUUC-Oni-083010	Oryza nivara	67.57	4.00e-54	201.00
IUUC-Opu-083784	Oryza punctata	66.22	1.00e-47	180.00
IUUC-Oru-084817	Oryza rufipogon	67.57	4.00e-54	201.00
IUUC-Osa-085291	Oryza sativa	67.57	4.00e-54	201.00
IUUC-Ola-087228	Oryzias latipes	68.48	2.00e-61	225.00
IUUC-Olu-087887	Ostreococcus lucimarinus	66.43	1.00e-56	210.00
IUUC-Oga-088473	Otolemur garnettii	69.06	9.00e-58	213.00
IUUC-Oar-090047	Ovis aries	70.68	3.00e-56	208.00
IUUC-Ptr-091331	Pan troglodytes	70.45	1.00e-55	206.00
IUUC-Pan-092230	Papio anubis	70.99	2.00e-55	206.00
IUUC-Psi-093996	Pelodiscus sinensis	70.68	4.00e-56	208.00
IUUC-Pno-094811	Phaeosphaeria nodorum	62.05	1.00e-51	193.00
IUUC-Ppa-095611	Physcomitrella patens	67.11	2.00e-60	222.00
IUUC-Pfo-096425	Poecilia formosa	68.48	6.00e-62	228.00
IUUC-Pab-098727	Pongo abelii	70.99	2.00e-55	206.00
IUUC-Pop-099881	Populus trichocarpa	65.87	7.00e-56	207.00
IUUC-Pca-100369	Procavia capensis	71.09	2.00e-52	196.00
IUUC-Ppe-101778	Prunus persica	65.79	2.00e-48	182.00
IUUC-Pva-103074	Pteropus vampyrus	70.99	2.00e-55	206.00
IUUC-Pgr-103274	Puccinia graminis	62.31	5.00e-52	194.00
IUUC-Pyt-104551	Pyrenophora triticirepentis	63.12	2.00e-50	189.00
IUUC-Rno-104929	Rattus norvegicus	70.99	2.00e-55	206.00
IUUC-Sha-106753	Sarcophilus harrisii	66.89	1.00e-58	216.00
IUUC-Sja-107917	Schizosaccharomyces japonicus	89.34	1.00e-64	236.00
IUUC-Smo-109401	Selaginella moellendorffii	67.13	9.00e-49	183.00
IUUC-Sit-110012	Setaria italica	58.56	7.00e-50	187.00
IUUC-Sly-111843	Solanum lycopersicum	64.46	4.00e-50	188.00
IUUC-Stu-112865	Solanum tuberosum	67.15	2.00e-48	182.00
IUUC-Sar-112992	Sorex araneus	50.35	5.00e-37	145.00
IUUC-Sbi-113787	Sorghum bicolor	64.24	1.00e-52	196.00
IUUC-Sre-114933	Sporisorium reilianum	64.63	2.00e-49	186.00
IUUC-Ssc-115912	Sus scrofa	70.37	2.00e-56	209.00
IUUC-Tgu-116635	Taeniopygia guttata	70.68	3.00e-56	208.00
IUUC-Tru-118534	Takifugu rubripes	67.88	2.00e-61	225.00
IUUC-Tsy-119168	Tarsius syrichta	70.99	2.00e-55	206.00
IUUC-Tni-119748	Tetraodon nigroviridis	67.27	5.00e-61	224.00
IUUC-Tca-121649	Theobroma cacao	64.18	1.00e-44	169.00
IUUC-Tae-123772	Triticum aestivum	65.06	8.00e-54	200.00
IUUC-Tur-126873	Triticum urartu	64.90	2.00e-53	200.00
IUUC-Tme-126974	Tuber melanosporum	63.80	7.00e-46	174.00
IUUC-Tbe-127917	Tupaia belangeri	70.45	1.00e-55	206.00
IUUC-Ttr-128609	Tursiops truncatus	70.99	3.00e-55	206.00
IUUC-Uma-129506	Ustilago maydis	65.31	4.00e-50	188.00
IUUC-Vpa-130208	Vicugna pacos	70.45	6.00e-56	208.00
IUUC-Vvi-131730	Vitis vinifera	67.79	2.00e-48	182.00
IUUC-Xtr-131942	Xenopus tropicalis	70.99	2.00e-55	206.00
IUUC-Xma-134052	Xiphophorus maculatus	68.48	1.00e-61	226.00
IUUC-Zma-135764	Zea mays	65.36	5.00e-49	184.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence