iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-087981

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03070100

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000007436.2	ENSOGAT00000007442.2	ENSOGAP00000006656.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.70e-71	239.7	69	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ ++++++  p++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPAFIKWLEEFTTQYTRDQKEHPPQQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 157
           9*****************************7777778888889999*************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e+++e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQSEitpkqitcrtRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 244
           *******************9..668888889998888888888999999999999********************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl k+P++L++hL+R s+
   Q: 245  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKIPQCLCIHLQRLSW 330
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts........peekqke.............................................. 274
           s++ + + k +++v+f++ L ++ +  +              +                                              
   Q: 331  SSH-GTPLKRHEHVQFNEFLIMDIYKYHllghkpnqH-----Npklkenpgpvlepqdgpappkpvpnhpgapktqifmngacspsllp 413
           998.8888*********88666644433345554440.....24455566666666666666777777777777777777777777777 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                              ++ ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 414  plpasvpfplpvvpdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSNQWLWVSDDTVRKASLQEVLS---SSAYLLFY 499
           77777777777777777779999***********************9999888888999*******************...******** PP
   S: 336  kr 337
           +r
   Q: 500  ER 501
           98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MLSSRAEAAM TAADRAIQRF LRTGAAVRYK VMKNWGVLGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFIKWLEEFT TQYTRDQKEH PPQQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAGCT CCCGGGCCGA GGCGGCCATG ACCGCGGCCG ACAGGGCCAT TCAGCGCTTC 60
TTGCGGACCG GGGCAGCCGT CAGGTGAGCC TGGGGGGGCG GGGCGGCCGA GAAGGCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	28.38	1.00e-15	77.40
IUUC-Aml-001733	Ailuropoda melanoleuca	92.69	0.00e+00	861.00
IUUC-Atr-002510	Amborella trichopoda	24.28	5.00e-21	95.90
IUUC-Apl-003645	Anas platyrhynchos	71.84	5.00e-106	376.00
IUUC-Aca-004583	Anolis carolinensis	68.42	1.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	25.42	4.00e-24	105.00
IUUC-Ath-007622	Arabidopsis thaliana	26.96	2.00e-24	107.00
IUUC-Ani-009286	Aspergillus nidulans	20.28	8.00e-11	62.40
IUUC-Ame-010896	Astyanax mexicanus	61.68	3.00e-153	534.00
IUUC-Bta-012321	Bos taurus	91.49	0.00e+00	854.00
IUUC-Bci-013641	Botrytis cinerea	23.24	2.00e-11	64.70
IUUC-Bdi-014795	Brachypodium distachyon	27.27	5.00e-18	85.50
IUUC-Bol-015637	Brassica oleracea	25.99	5.00e-23	102.00
IUUC-Bra-016801	Brassica rapa	25.37	7.00e-25	108.00
IUUC-Cel-018308	Caenorhabditis elegans	27.47	5.00e-36	145.00
IUUC-Cja-018826	Callithrix jacchus	94.98	0.00e+00	929.00
IUUC-Cfa-021206	Canis familiaris	90.96	0.00e+00	873.00
IUUC-Cpo-021343	Cavia porcellus	92.02	0.00e+00	856.00
IUUC-Csa-023419	Chlorocebus sabaeus	94.97	0.00e+00	928.00
IUUC-Cho-024475	Choloepus hoffmanni	88.36	2.00e-136	479.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.63	3.00e-12	67.00
IUUC-Cne-027061	Cryptococcus neoformans	24.62	3.00e-09	57.00
IUUC-Dre-027563	Danio rerio	58.47	7.00e-158	550.00
IUUC-Dno-029929	Dasypus novemcinctus	91.88	0.00e+00	894.00
IUUC-Dor-030166	Dipodomys ordii	82.98	0.00e+00	744.00
IUUC-Dse-031517	Dothistroma septosporum	22.39	6.00e-11	62.80
IUUC-Dme-031627	Drosophila melanogaster	32.76	1.00e-30	127.00
IUUC-Ete-032634	Echinops telfairi	79.73	0.00e+00	684.00
IUUC-Eca-033968	Equus caballus	92.65	0.00e+00	838.00
IUUC-Eeu-035279	Erinaceus europaeus	81.10	3.00e-58	219.00
IUUC-Fca-036525	Felis catus	93.04	0.00e+00	893.00
IUUC-Fal-036606	Ficedula albicollis	74.80	5.00e-158	550.00
IUUC-Fox-037837	Fusarium oxysporum	23.87	4.00e-13	69.70
IUUC-Gmo-038726	Gadus morhua	55.38	2.00e-142	499.00
IUUC-Gga-040718	Gallus gallus	75.19	3.00e-162	564.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.49	3.00e-151	528.00
IUUC-Gma-042890	Glycine max	25.42	5.00e-28	119.00
IUUC-Ggo-045021	Gorilla gorilla	94.97	0.00e+00	927.00
IUUC-Hsa-045832	Homo sapiens	94.97	0.00e+00	927.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	94.08	0.00e+00	855.00
IUUC-Lch-050662	Latimeria chalumnae	69.49	1.00e-179	622.00
IUUC-Lpe-051078	Leersia perrieri	26.21	4.00e-30	125.00
IUUC-Loc-052611	Lepisosteus oculatus	65.75	2.00e-178	618.00
IUUC-Lma-053048	Leptosphaeria maculans	20.24	2.00e-15	77.80
IUUC-Laf-053752	Loxodonta africana	92.24	0.00e+00	837.00
IUUC-Mcc-054892	Macaca mulatta	95.36	0.00e+00	932.00
IUUC-Meu-056673	Macropus eugenii	74.67	4.00e-164	570.00
IUUC-Mtr-057976	Medicago truncatula	26.35	7.00e-35	142.00
IUUC-Mga-059543	Meleagris gallopavo	76.82	0.00e+00	664.00
IUUC-Mmr-061534	Microcebus murinus	95.74	0.00e+00	903.00
IUUC-Mdo-062140	Monodelphis domestica	70.36	6.00e-168	583.00
IUUC-Mmu-063673	Mus musculus	89.17	0.00e+00	834.00
IUUC-Mpu-066328	Mustela putorius furo	92.26	0.00e+00	853.00
IUUC-Mlu-067938	Myotis lucifugus	93.02	0.00e+00	920.00
IUUC-Nle-069426	Nomascus leucogenys	93.67	0.00e+00	826.00
IUUC-Opr-070796	Ochotona princeps	84.44	7.00e-120	424.00
IUUC-Ont-072248	Oreochromis niloticus	58.07	2.00e-156	545.00
IUUC-Oan-072916	Ornithorhynchus anatinus	80.51	0.00e+00	766.00
IUUC-Ocu-074459	Oryctolagus cuniculus	87.69	0.00e+00	662.00
IUUC-Oba-075765	Oryza barthii	25.14	1.00e-28	121.00
IUUC-Obr-076005	Oryza brachyantha	26.17	2.00e-31	130.00
IUUC-Ogl-077916	Oryza glaberrima	25.89	1.00e-31	130.00
IUUC-Ogu-078263	Oryza glumaepatula	25.37	1.00e-29	124.00
IUUC-Oin-080096	Oryza indica	25.84	7.00e-23	101.00
IUUC-Ome-081928	Oryza meridionalis	25.56	9.00e-30	124.00
IUUC-Oni-082424	Oryza nivara	25.51	2.00e-29	123.00
IUUC-Oru-085117	Oryza rufipogon	25.51	2.00e-29	123.00
IUUC-Ola-087429	Oryzias latipes	56.08	1.00e-146	512.00
IUUC-Oar-089927	Ovis aries	90.91	0.00e+00	848.00
IUUC-Ptr-090878	Pan troglodytes	94.97	0.00e+00	927.00
IUUC-Pan-092698	Papio anubis	95.36	0.00e+00	932.00
IUUC-Psi-093451	Pelodiscus sinensis	77.24	0.00e+00	717.00
IUUC-Pno-094802	Phaeosphaeria nodorum	22.37	6.00e-10	58.90
IUUC-Pfo-096096	Poecilia formosa	58.00	9.00e-155	540.00
IUUC-Pab-098676	Pongo abelii	93.99	0.00e+00	915.00
IUUC-Pca-100418	Procavia capensis	95.79	2.00e-129	455.00
IUUC-Ppe-101898	Prunus persica	24.37	1.00e-24	107.00
IUUC-Pva-103018	Pteropus vampyrus	90.52	0.00e+00	867.00
IUUC-Pgr-103423	Puccinia graminis	26.80	4.00e-10	60.50
IUUC-Pte-104330	Pyrenophora teres	21.55	3.00e-15	77.00
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.05	2.00e-16	81.30
IUUC-Rno-105708	Rattus norvegicus	87.81	0.00e+00	825.00
IUUC-Sha-106971	Sarcophilus harrisii	80.11	0.00e+00	781.00
IUUC-Sit-110442	Setaria italica	26.14	4.00e-27	115.00
IUUC-Sly-110928	Solanum lycopersicum	23.50	4.00e-15	75.90
IUUC-Ssc-116397	Sus scrofa	90.91	0.00e+00	847.00
IUUC-Tgu-117446	Taeniopygia guttata	70.35	0.00e+00	642.00
IUUC-Tru-118268	Takifugu rubripes	56.60	2.00e-141	495.00
IUUC-Tsy-119484	Tarsius syrichta	92.06	6.00e-51	195.00
IUUC-Tni-119735	Tetraodon nigroviridis	53.55	2.00e-120	425.00
IUUC-Tca-121660	Theobroma cacao	25.23	9.00e-29	121.00
IUUC-Tvi-122428	Trichoderma virens	22.98	5.00e-15	75.90
IUUC-Tae-125383	Triticum aestivum	27.98	4.00e-29	122.00
IUUC-Tur-126458	Triticum urartu	26.36	1.00e-23	104.00
IUUC-Tme-126993	Tuber melanosporum	27.80	6.00e-12	65.90
IUUC-Tbe-127740	Tupaia belangeri	87.23	0.00e+00	791.00
IUUC-Ttr-129273	Tursiops truncatus	90.33	0.00e+00	845.00
IUUC-Vda-129789	Verticillium dahliae	22.84	1.00e-08	55.50
IUUC-Vvi-131177	Vitis vinifera	25.91	3.00e-27	116.00
IUUC-Xtr-132374	Xenopus tropicalis	65.34	1.00e-172	599.00
IUUC-Xma-133267	Xiphophorus maculatus	60.48	1.00e-156	545.00
IUUC-Zma-135796	Zea mays	26.01	6.00e-18	85.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence